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Volumn 21, Issue , 2015, Pages S25-S31

Detection and clinical significance of circulating tumor cells in colorectal cancer—20 years of progress

Author keywords

[No Author keywords available]

Indexed keywords

ACHAETESCUTE COMPLEX HOMOLOG 2; BMI1 PROTEIN; CELL MARKER; EPITHELIAL CELL ADHESION MOLECULE; OLFACTOMEDIN 4; PROTEIN LGR5; UNCLASSIFIED DRUG; ASCL2 PROTEIN, HUMAN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BIOLOGICAL MARKER; G PROTEIN COUPLED RECEPTOR; GRANULOCYTE COLONY STIMULATING FACTOR; LGR5 PROTEIN, HUMAN; OLFM4 PROTEIN, HUMAN;

EID: 84945948733     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.2119/molmed.2015.00149     Document Type: Article
Times cited : (126)

References (67)
  • 3
    • 63049102497 scopus 로고    scopus 로고
    • Parallel progression of primary tumours and metastases
    • Klein C. (2009) Parallel progression of primary tumours and metastases. Nat. Rev. Cancer. 9:302-312.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 302-312
    • Klein, C.1
  • 4
    • 0029411670 scopus 로고
    • Detection of circulating tumor cells in colorectal cancer by immunobead-PCR is a sensitive prognostic marker for relapse of disease
    • Hardingham JE, et al. (1995) Detection of circulating tumor cells in colorectal cancer by immunobead-PCR is a sensitive prognostic marker for relapse of disease. Mol. Med. 1:789-794.
    • (1995) Mol. Med , vol.1 , pp. 789-794
    • Hardingham, J.E.1
  • 5
    • 0034797164 scopus 로고    scopus 로고
    • Detection and clinical significance of occult tumour cells in colorectal cancer
    • Tsavellas G, Patel H, Allen-Mersh TG. (2001) Detection and clinical significance of occult tumour cells in colorectal cancer. Br. J. Surg. 88:1307-1320.
    • (2001) Br. J. Surg , vol.88 , pp. 1307-1320
    • Tsavellas, G.1    Patel, H.2    Allen-Mersh, T.G.3
  • 6
    • 0034688316 scopus 로고    scopus 로고
    • Molecular detection of blood-borne epithelial cells in colorectal cancer patients and in patients with benign bowel disease
    • Hardingham JE, et al. (2000) Molecular detection of blood-borne epithelial cells in colorectal cancer patients and in patients with benign bowel disease. Int. J. Cancer 89:8-13.
    • (2000) Int. J. Cancer , vol.89 , pp. 8-13
    • Hardingham, J.E.1
  • 7
    • 53249084205 scopus 로고    scopus 로고
    • Quantitative RT-PCR detection of colorectal tumor cells in peripheral blood-a systematic review
    • Sergeant G, Penninckx F, Topal B. (2008) Quantitative RT-PCR detection of colorectal tumor cells in peripheral blood-a systematic review. J. Surg. Res. 150:144-152.
    • (2008) J. Surg. Res , vol.150 , pp. 144-152
    • Sergeant, G.1    Penninckx, F.2    Topal, B.3
  • 8
    • 84881542996 scopus 로고    scopus 로고
    • Circulating tumor cells in colorectal cancer patients
    • Torino F, et al. (2013) Circulating tumor cells in colorectal cancer patients. Cancer Treat. Rev. 39:759-772.
    • (2013) Cancer Treat. Rev , vol.39 , pp. 759-772
    • Torino, F.1
  • 9
    • 84889040481 scopus 로고    scopus 로고
    • Technologies for detection of circulating tumor cells: Facts and vision
    • Alix-Panabieres C, Pantel K. (2014) Technologies for detection of circulating tumor cells: facts and vision. Lab Chip. 14:57-62.
    • (2014) Lab Chip , vol.14 , pp. 57-62
    • Alix-Panabieres, C.1    Pantel, K.2
  • 10
    • 84876257938 scopus 로고    scopus 로고
    • Shift to earlier stage at diagnosis as a consequence of the National Bowel Cancer Screening Program
    • Cole SR, et al. (2013) Shift to earlier stage at diagnosis as a consequence of the National Bowel Cancer Screening Program. Med. J. Aust. 198:327-330.
    • (2013) Med. J. Aust , vol.198 , pp. 327-330
    • Cole, S.R.1
  • 11
    • 84929193398 scopus 로고    scopus 로고
    • Colorectal cancer treatment and survival: The experience of major public hospitals in South Australia over three decades
    • Roder D, et al. (2015) Colorectal cancer treatment and survival: the experience of major public hospitals in South Australia over three decades. Asian Pac. J. Cancer Prev. 16:2431-2440.
    • (2015) Asian Pac. J. Cancer Prev , vol.16 , pp. 2431-2440
    • Roder, D.1
  • 12
    • 84870041469 scopus 로고    scopus 로고
    • Long-term outcomes of the australasian randomized clinical trial comparing laparoscopic and conventional open surgical treatments for colon cancer: The Australasian Laparoscopic Colon Cancer Study trial
    • Bagshaw PF, et al. (2012) Long-term outcomes of the australasian randomized clinical trial comparing laparoscopic and conventional open surgical treatments for colon cancer: the Australasian Laparoscopic Colon Cancer Study trial. Ann. Surg. 256:915-919.
    • (2012) Ann. Surg , vol.256 , pp. 915-919
    • Bagshaw, P.F.1
  • 13
    • 31544468441 scopus 로고    scopus 로고
    • Identification of early-stage colorectal cancer patients at risk of relapse postresection by immunobead reverse transcription-PCR analysis of peritoneal lavage fluid for malignant cells
    • Lloyd JM, et al. (2006) Identification of early-stage colorectal cancer patients at risk of relapse postresection by immunobead reverse transcription-PCR analysis of peritoneal lavage fluid for malignant cells. Clin. Cancer Res. 12:417-423.
    • (2006) Clin. Cancer Res , vol.12 , pp. 417-423
    • Lloyd, J.M.1
  • 14
    • 36849064682 scopus 로고    scopus 로고
    • Adjuvant chemotherapy versus observation in patients with colorectal cancer: A randomised study
    • Gray R, et al. (2007) Adjuvant chemotherapy versus observation in patients with colorectal cancer: a randomised study. Lancet. 370:2020-2029.
    • (2007) Lancet , vol.370 , pp. 2020-2029
    • Gray, R.1
  • 15
    • 42649100970 scopus 로고    scopus 로고
    • Detection, clinical relevance and specific biological properties of disseminating tumour cells
    • Pantel K, Brakenhoff RH, Brandt B. (2008) Detection, clinical relevance and specific biological properties of disseminating tumour cells. Nat. Rev. Cancer. 8:329-340.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 329-340
    • Pantel, K.1    Brakenhoff, R.H.2    Brandt, B.3
  • 16
    • 0027239995 scopus 로고
    • Immunobead-PCR: A technique for the detection of circulating tumor cells using immunomagnetic beads and the polymerase chain reaction
    • Hardingham JE, et al. (1993) Immunobead-PCR: a technique for the detection of circulating tumor cells using immunomagnetic beads and the polymerase chain reaction. Cancer Res. 53:3455-3458.
    • (1993) Cancer Res , vol.53 , pp. 3455-3458
    • Hardingham, J.E.1
  • 17
    • 4143094988 scopus 로고    scopus 로고
    • Circulating tumor cells, disease progression, and survival in metastatic breast cancer
    • Cristofanilli M, et al. (2004) Circulating tumor cells, disease progression, and survival in metastatic breast cancer. New Engl. J. Med. 351:781-791.
    • (2004) New Engl. J. Med , vol.351 , pp. 781-791
    • Cristofanilli, M.1
  • 18
    • 33847402612 scopus 로고    scopus 로고
    • Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: A validation study of the CellSearch system
    • Riethdorf S, et al. (2007) Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch system. Clin. Cancer Res. 13:920-928.
    • (2007) Clin. Cancer Res , vol.13 , pp. 920-928
    • Riethdorf, S.1
  • 19
    • 49249130844 scopus 로고    scopus 로고
    • Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer
    • Cohen SJ, et al. (2008) Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer. J. Clin. Oncol. 26:3213-3221.
    • (2008) J. Clin. Oncol , vol.26 , pp. 3213-3221
    • Cohen, S.J.1
  • 20
    • 58149165081 scopus 로고    scopus 로고
    • Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer
    • de Bono JS, et al. (2008) Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer. Clin. Cancer Res. 14:6302-6309.
    • (2008) Clin. Cancer Res , vol.14 , pp. 6302-6309
    • de Bono, J.S.1
  • 21
    • 77950458280 scopus 로고    scopus 로고
    • Meta-analysis shows that detection of circulating tumor cells indicates poor prognosis in patients with colorectal cancer
    • Rahbari NN, et al. (2010) Meta-analysis shows that detection of circulating tumor cells indicates poor prognosis in patients with colorectal cancer. Gastroenterology. 138:1714-1726.e1713.
    • (2010) Gastroenterology , vol.138
    • Rahbari, N.N.1
  • 22
    • 84878828739 scopus 로고    scopus 로고
    • Circulating tumor cells and prognosis of patients with resectable colorectal liver metastases or widespread metastatic colorectal cancer: A meta-analysis
    • Groot Koerkamp B, Rahbari N, Büchler M, Koch M, Weitz J. (2013) Circulating tumor cells and prognosis of patients with resectable colorectal liver metastases or widespread metastatic colorectal cancer: a meta-analysis. Ann. Surg. Oncol. 20:2156-2165.
    • (2013) Ann. Surg. Oncol , vol.20 , pp. 2156-2165
    • Groot Koerkamp, B.1    Rahbari, N.2    Büchler, M.3    Koch, M.4    Weitz, J.5
  • 23
    • 84860660477 scopus 로고    scopus 로고
    • Circulating epithelial cells in patients with benign colon diseases
    • Pantel K, et al. (2012) Circulating epithelial cells in patients with benign colon diseases. Clin. Chem. 58:936-940.
    • (2012) Clin. Chem , vol.58 , pp. 936-940
    • Pantel, K.1
  • 24
    • 84921636121 scopus 로고    scopus 로고
    • Circulating tumor cell enumeration by the CellSearch system: The clinician's guide to breast cancer treatment? Cancer Treat
    • Beije N, Jager A, Sleijfer S. (2015) Circulating tumor cell enumeration by the CellSearch system: the clinician's guide to breast cancer treatment? Cancer Treat. Rev. 41:144-150.
    • (2015) Rev , vol.41 , pp. 144-150
    • Beije, N.1    Jager, A.2    Sleijfer, S.3
  • 25
    • 84875211452 scopus 로고    scopus 로고
    • Circulating tumor cells as a surrogate marker for determining clinical outcome to mFOLFOX chemotherapy in patients with stage III colon cancer
    • Lu CY, et al. (2013) Circulating tumor cells as a surrogate marker for determining clinical outcome to mFOLFOX chemotherapy in patients with stage III colon cancer. Br. J. Cancer. 108:791-797.
    • (2013) Br. J. Cancer , vol.108 , pp. 791-797
    • Lu, C.Y.1
  • 26
    • 84929507812 scopus 로고    scopus 로고
    • Circulating tumor cell enumeration in a phase II trial of a four-drug regimen in advanced colorectal cancer
    • Krebs MG, et al. (2015) Circulating tumor cell enumeration in a phase II trial of a four-drug regimen in advanced colorectal cancer. Clin. Colorectal Cancer. 14:115-122.
    • (2015) Clin. Colorectal Cancer , vol.14 , pp. 115-122
    • Krebs, M.G.1
  • 27
    • 84928211139 scopus 로고    scopus 로고
    • Circulating tumour cells and outcome in non-metastatic colorectal cancer: A prospective study
    • Bork U, et al. (2015) Circulating tumour cells and outcome in non-metastatic colorectal cancer: a prospective study. Br. J. Cancer. 112:1306-1313.
    • (2015) Br. J. Cancer , vol.112 , pp. 1306-1313
    • Bork, U.1
  • 28
    • 34347353063 scopus 로고    scopus 로고
    • Circulating tumor cells (CTC) detection: Clinical impact and future directions
    • Paterlini-Brechot P, Benali NL. (2007) Circulating tumor cells (CTC) detection: clinical impact and future directions. Cancer Lett. 253:180-204.
    • (2007) Cancer Lett , vol.253 , pp. 180-204
    • Paterlini-Brechot, P.1    Benali, N.L.2
  • 29
    • 79952770095 scopus 로고    scopus 로고
    • Circulating tumour cells: Their utility in cancer management and predicting outcomes
    • Krebs MG, Hou JM, Ward TH, Blackhall FH, Dive C. (2010) Circulating tumour cells: their utility in cancer management and predicting outcomes. Ther. Adv. Med. Oncol. 2:351-365.
    • (2010) Ther. Adv. Med. Oncol , vol.2 , pp. 351-365
    • Krebs, M.G.1    Hou, J.M.2    Ward, T.H.3    Blackhall, F.H.4    Dive, C.5
  • 30
    • 77952419985 scopus 로고    scopus 로고
    • Circulating tumour cells early predict progression-free and overall survival in advanced colorectal cancer patients treated with chemotherapy and targeted agents
    • Tol J, et al. (2010) Circulating tumour cells early predict progression-free and overall survival in advanced colorectal cancer patients treated with chemotherapy and targeted agents. Ann. Oncol. 21:1006-1012.
    • (2010) Ann. Oncol , vol.21 , pp. 1006-1012
    • Tol, J.1
  • 31
    • 24644451986 scopus 로고    scopus 로고
    • Expression of epithelial cell adhesion molecule in carcinoma cells present in blood and primary and metastatic tumors
    • Rao CG, et al. (2005) Expression of epithelial cell adhesion molecule in carcinoma cells present in blood and primary and metastatic tumors. Int. J. Oncol. 27:49-57.
    • (2005) Int. J. Oncol , vol.27 , pp. 49-57
    • Rao, C.G.1
  • 32
    • 79954496657 scopus 로고    scopus 로고
    • Comparison of three distinct methods for the detection of circulating tumor cells in colorectal cancer patients
    • Gervasoni A, et al. (2011) Comparison of three distinct methods for the detection of circulating tumor cells in colorectal cancer patients. Oncol. Rep. 25:1669-1703.
    • (2011) Oncol. Rep , vol.25 , pp. 1669-1703
    • Gervasoni, A.1
  • 33
    • 84905174495 scopus 로고    scopus 로고
    • Circulating tumour cells: The evolving concept and the inadequacy of their enrichment by EpCAM-based methodology for basic and clinical cancer research
    • Grover PK, Cummins AG, Price TJ, Roberts-Thomson IC, Hardingham JE. (2014) Circulating tumour cells: the evolving concept and the inadequacy of their enrichment by EpCAM-based methodology for basic and clinical cancer research. Ann. Oncol. 25:1506-1516.
    • (2014) Ann. Oncol , vol.25 , pp. 1506-1516
    • Grover, P.K.1    Cummins, A.G.2    Price, T.J.3    Roberts-Thomson, I.C.4    Hardingham, J.E.5
  • 34
    • 12444278131 scopus 로고    scopus 로고
    • Rare expression of epithelial cell adhesion molecule on residual micrometastatic breast cancer cells after adjuvant chemotherapy
    • Thurm H, et al. (2003) Rare expression of epithelial cell adhesion molecule on residual micrometastatic breast cancer cells after adjuvant chemotherapy. Clin. Cancer Res. 9:2598-2604.
    • (2003) Clin. Cancer Res , vol.9 , pp. 2598-2604
    • Thurm, H.1
  • 35
    • 84860999602 scopus 로고    scopus 로고
    • Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition
    • Gorges T, et al. (2012) Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition. BMC Cancer. 12:178.
    • (2012) BMC Cancer , vol.12 , pp. 178
    • Gorges, T.1
  • 36
    • 81255205399 scopus 로고    scopus 로고
    • Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis
    • Labelle M, Begum S, Hynes RO. (2011) Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis. Cancer Cell. 20:576-590.
    • (2011) Cancer Cell , vol.20 , pp. 576-590
    • Labelle, M.1    Begum, S.2    Hynes, R.O.3
  • 37
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • Polyak K, Weinberg RA. (2009) Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat. Rev. Cancer. 9:265-273.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 38
    • 84867985453 scopus 로고    scopus 로고
    • Plasticity of disseminating cancer cells in patients with epithelial malignancies
    • Bednarz-Knoll N, Alix-Panabières C, Pantel K. (2012) Plasticity of disseminating cancer cells in patients with epithelial malignancies. Cancer Metastasis Rev. 31:673-687.
    • (2012) Cancer Metastasis Rev , vol.31 , pp. 673-687
    • Bednarz-Knoll, N.1    Alix-Panabières, C.2    Pantel, K.3
  • 39
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, et al. (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell. 133:704-715.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1
  • 40
    • 84929645752 scopus 로고    scopus 로고
    • EMT, CTCs and CSCs in tumor relapse and drug-resistance
    • Mitra A, Mishra L, Li S. (2015) EMT, CTCs and CSCs in tumor relapse and drug-resistance. Oncotarget. 6:10697-10711.
    • (2015) Oncotarget , vol.6 , pp. 10697-10711
    • Mitra, A.1    Mishra, L.2    Li, S.3
  • 41
    • 79955016306 scopus 로고    scopus 로고
    • Circulating tumor cells: Not all detected cells are bad and not all bad cells are detected
    • Wicha MS, Hayes DF. (2011) Circulating tumor cells: not all detected cells are bad and not all bad cells are detected. J. Clin. Oncol. 29:1508-1511.
    • (2011) J. Clin. Oncol , vol.29 , pp. 1508-1511
    • Wicha, M.S.1    Hayes, D.F.2
  • 43
    • 84925484852 scopus 로고    scopus 로고
    • Circulating tumor cells: Who is the killer?
    • Paterlini-Bréchot P. (2014) Circulating tumor cells: who is the killer? Cancer Microenviron. 7:161-176.
    • (2014) Cancer Microenviron , vol.7 , pp. 161-176
    • Paterlini-Bréchot, P.1
  • 44
    • 77956641496 scopus 로고    scopus 로고
    • A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer
    • Pang R, et al. (2010) A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer. Cell Stem Cell. 6:603-615.
    • (2010) Cell Stem Cell , vol.6 , pp. 603-615
    • Pang, R.1
  • 45
    • 79955030814 scopus 로고    scopus 로고
    • Clinical significance of circulating tumor cells, including cancer stem-like cells, in peripheral blood for recurrence and prognosis in patients with Dukes' stage B and C colorectal cancer
    • Iinuma H, et al. (2011) Clinical significance of circulating tumor cells, including cancer stem-like cells, in peripheral blood for recurrence and prognosis in patients with Dukes' stage B and C colorectal cancer. J. Clin. Oncol. 29:1547-1555.
    • (2011) J. Clin. Oncol , vol.29 , pp. 1547-1555
    • Iinuma, H.1
  • 46
    • 84860162754 scopus 로고    scopus 로고
    • Evaluation of the adenocarcinoma-associated gene AGR2 and the intestinal stem cell marker LGR5 as biomarkers in colorectal cancer
    • Valladares-Ayerbes M, et al. (2012) Evaluation of the adenocarcinoma-associated gene AGR2 and the intestinal stem cell marker LGR5 as biomarkers in colorectal cancer. Int. J. Mol. Sci. 13:4367-4387.
    • (2012) Int. J. Mol. Sci , vol.13 , pp. 4367-4387
    • Valladares-Ayerbes, M.1
  • 47
    • 84926349188 scopus 로고    scopus 로고
    • LGR5, a relevant marker of cancer stem cells, indicates a poor prognosis in colorectal cancer patients: A meta-analysis
    • Han Y, et al. (2015) LGR5, a relevant marker of cancer stem cells, indicates a poor prognosis in colorectal cancer patients: a meta-analysis. Clin. Res. Hepatol. Gastroenterol. 39:267-273.
    • (2015) Clin. Res. Hepatol. Gastroenterol , vol.39 , pp. 267-273
    • Han, Y.1
  • 48
    • 0037222688 scopus 로고    scopus 로고
    • VEGFR-3 and CD133 identify a population of CD34+ lymphatic/vascular endothelial precursor cells
    • Salven P, Mustjoki S, Alitalo R, Alitalo K, Rafii S. (2002) VEGFR-3 and CD133 identify a population of CD34+ lymphatic/vascular endothelial precursor cells. Blood. 101:168-172.
    • (2002) Blood , vol.101 , pp. 168-172
    • Salven, P.1    Mustjoki, S.2    Alitalo, R.3    Alitalo, K.4    Rafii, S.5
  • 49
    • 84904707313 scopus 로고    scopus 로고
    • Stem cells marked by the R-spondin receptor LGR5
    • Koo B-K, Clevers H. (2014) Stem cells marked by the R-spondin receptor LGR5. Gastroenterology. 147:289-302.
    • (2014) Gastroenterology , vol.147 , pp. 289-302
    • Koo, B.-K.1    Clevers, H.2
  • 50
    • 79952202070 scopus 로고    scopus 로고
    • Stem cell marker olfactomedin 4: Critical appraisal of its characteristics and role in tumorigenesis
    • Grover PK, Hardingham JE, Cummins AG. (2010) Stem cell marker olfactomedin 4: critical appraisal of its characteristics and role in tumorigenesis. Cancer Metastasis Rev. 29:761-775.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 761-775
    • Grover, P.K.1    Hardingham, J.E.2    Cummins, A.G.3
  • 51
    • 67649240439 scopus 로고    scopus 로고
    • OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells
    • van der Flier LG, Haegebarth A, Stange DE, van de Wetering M, Clevers H. (2009) OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells. Gastroenterology. 137:15-17.
    • (2009) Gastroenterology , vol.137 , pp. 15-17
    • van der Flier, L.G.1    Haegebarth, A.2    Stange, D.E.3    van de Wetering, M.4    Clevers, H.5
  • 52
    • 35548974423 scopus 로고    scopus 로고
    • Identification of stem cells in small intestine and colon by marker gene Lgr5
    • Barker N, et al. (2007) Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature. 449:1003-1007.
    • (2007) Nature , vol.449 , pp. 1003-1007
    • Barker, N.1
  • 53
    • 80054857419 scopus 로고    scopus 로고
    • Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium
    • Sato T, et al. (2011) Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. Gastroenterology. 141:1762-1772.
    • (2011) Gastroenterology , vol.141 , pp. 1762-1772
    • Sato, T.1
  • 54
    • 84875999237 scopus 로고    scopus 로고
    • Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis
    • Yokobori T, et al. (2013) Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis. Cancer Res. 73:2059-2069.
    • (2013) Cancer Res , vol.73 , pp. 2059-2069
    • Yokobori, T.1
  • 55
    • 79954987871 scopus 로고    scopus 로고
    • Colon cancer stem cells: Implications in carcinogenesis
    • Sanders MA, Majumdar APN. (2011) Colon cancer stem cells: implications in carcinogenesis. Front. Biosci. 16:1651-1662.
    • (2011) Front. Biosci , vol.16 , pp. 1651-1662
    • Sanders, M.A.1    Majumdar, A.P.N.2
  • 56
    • 84883178190 scopus 로고    scopus 로고
    • Isolation and phenotypic characterization of colorectal cancer stem cells with organ-specific metastatic potential
    • Gao W, et al. (2013) Isolation and phenotypic characterization of colorectal cancer stem cells with organ-specific metastatic potential. Gastroenterology. 145:636-646.e5.
    • (2013) Gastroenterology , vol.145
    • Gao, W.1
  • 57
    • 84899726033 scopus 로고    scopus 로고
    • Evaluation of cancer stem cell markers CD133, CD44, CD24: Association with AKT isoforms and radiation resistance in colon cancer cells
    • Sahlberg SH, Spiegelberg D, Glimelius B, Stenerlöw B, Nestor M. (2014) Evaluation of cancer stem cell markers CD133, CD44, CD24: association with AKT isoforms and radiation resistance in colon cancer cells. PLoS One. 9:e94621.
    • (2014) PLoS One , vol.9
    • Sahlberg, S.H.1    Spiegelberg, D.2    Glimelius, B.3    Stenerlöw, B.4    Nestor, M.5
  • 58
    • 84920078382 scopus 로고    scopus 로고
    • Methods for detecting circulating cancer stem cells (CCSCs) as a novel approach for diagnosis of colon cancer relapse/ metastasis
    • Kantara C, et al. (2015) Methods for detecting circulating cancer stem cells (CCSCs) as a novel approach for diagnosis of colon cancer relapse/ metastasis. Lab. Invest. 95:100-112.
    • (2015) Lab. Invest , vol.95 , pp. 100-112
    • Kantara, C.1
  • 59
    • 84891880112 scopus 로고    scopus 로고
    • Circulating tumor cells: Advances in isolation and analysis, and challenges for clinical applications
    • Harouaka R, Kang Z, Zheng S, Cao L. (2014) Circulating tumor cells: advances in isolation and analysis, and challenges for clinical applications. Pharmacol. Ther. 141:209-221.
    • (2014) Pharmacol. Ther , vol.141 , pp. 209-221
    • Harouaka, R.1    Kang, Z.2    Zheng, S.3    Cao, L.4
  • 60
    • 84906731563 scopus 로고    scopus 로고
    • Challenges in circulating tumour cell research
    • Alix-Panabieres C, Pantel K. (2014) Challenges in circulating tumour cell research. Nat. Rev. Cancer. 14:623-631.
    • (2014) Nat. Rev. Cancer , vol.14 , pp. 623-631
    • Alix-Panabieres, C.1    Pantel, K.2
  • 61
    • 84929359321 scopus 로고    scopus 로고
    • Benchtop technologies for circulating tumor cells separation based on biophysical properties
    • Low WS, Wan Abas WA. (2015) Benchtop technologies for circulating tumor cells separation based on biophysical properties. Biomed Res. Int. 2015:239362.
    • (2015) Biomed Res. Int , vol.2015 , pp. 239362
    • Low, W.S.1    Wan Abas, W.A.2
  • 62
    • 84883597308 scopus 로고    scopus 로고
    • Nanostructured substrates for isolation of circulating tumor cells
    • Wang L, Asghar W, Demirci U, Wan Y. (2013) Nanostructured substrates for isolation of circulating tumor cells. Nano Today. 8:347-387.
    • (2013) Nano Today , vol.8 , pp. 347-387
    • Wang, L.1    Asghar, W.2    Demirci, U.3    Wan, Y.4
  • 63
    • 84872833958 scopus 로고    scopus 로고
    • Nanoroughened surfaces for efficient capture of circulating tumor cells without using capture antibodies
    • Chen W, et al. (2013) Nanoroughened surfaces for efficient capture of circulating tumor cells without using capture antibodies. ACS Nano. 7:566-575.
    • (2013) ACS Nano , vol.7 , pp. 566-575
    • Chen, W.1
  • 64
    • 84917706893 scopus 로고    scopus 로고
    • Nanostructured polystyrene well plates allow unbiased high-throughput characterization of circulating tumor cells
    • Wan Y, et al. (2014) Nanostructured polystyrene well plates allow unbiased high-throughput characterization of circulating tumor cells. ACS Appl. Mater. Interfaces. 6:20828-20836.
    • (2014) ACS Appl. Mater. Interfaces , vol.6 , pp. 20828-20836
    • Wan, Y.1
  • 65
    • 84863938828 scopus 로고    scopus 로고
    • High-throughput singlemicroparticle imaging flow analyzer
    • Goda K, et al. (2012) High-throughput singlemicroparticle imaging flow analyzer. Proc. Natl. Acad. Sci. U. S. A. 109:11630-11635.
    • (2012) Proc. Natl. Acad. Sci. U. S. A , vol.109 , pp. 11630-11635
    • Goda, K.1
  • 66
    • 84988602764 scopus 로고    scopus 로고
    • Quantitative characterization of androgen receptor protein expression and cellular localization in circulating tumor cells from patients with metastatic castration-resistant prostate cancer
    • Reyes EE, et al. (2014) Quantitative characterization of androgen receptor protein expression and cellular localization in circulating tumor cells from patients with metastatic castration-resistant prostate cancer. J. Transl. Med. 12:313.
    • (2014) J. Transl. Med , vol.12 , pp. 313
    • Reyes, E.E.1
  • 67
    • 84889061556 scopus 로고    scopus 로고
    • Slanted spiral microfluidics for the ultra-fast, label-free isolation of circulating tumor cells
    • Warkiani ME, et al. (2014) Slanted spiral microfluidics for the ultra-fast, label-free isolation of circulating tumor cells. Lab Chip. 14:128-137.
    • (2014) Lab Chip , vol.14 , pp. 128-137
    • Warkiani, M.E.1


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