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Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 22, 2015, Pages 5270-5276

Monoamine oxidase inhibitory activities of heterocyclic chalcones

(4) Minders, Corné a Petzer, Jacobus P a Petzer, Anél a Lourens, Anna C U a

a NORTH WEST UNIVERSITY (South Africa)

Author keywords

Chalcone; Competitive; Inhibition; Monoamine oxidase (MAO); Reversible

Indexed keywords

CHALCONE DERIVATIVE; FURAN; HETEROCYCLIC COMPOUND; HYDROGEN PEROXIDE; MONOAMINE OXIDASE A INHIBITOR; MONOAMINE OXIDASE B INHIBITOR; MONOAMINE OXIDASE INHIBITOR; THIOPHENE; 1-(1H-PYRROL-2-YL)-3-(4-(TRIFLUOROMETHYL)PHENYL)PROP-2-EN-1-ONE; 3-(3-BROMO-4-FLUOROPHENYL)-1-(5-METHYLTHIOPHEN-2-YL)PROP-2-EN-1-ONE; AMINE OXIDASE (FLAVIN CONTAINING); ANTIPARKINSON AGENT; FLUORINATED HYDROCARBON; KYNURAMINE; MONOAMINE OXIDASE A, HUMAN; PYRROLE DERIVATIVE; THIOPHENE DERIVATIVE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG POTENCY; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC50; IMMUNOGENICITY; OXIDATIVE STRESS; PARKINSON DISEASE; PROTON NUCLEAR MAGNETIC RESONANCE; SPECTROFLUOROMETRY; STRUCTURE ACTIVITY RELATION; HELA CELL LINE; HUMAN; KINETICS; METABOLISM; SYNTHESIS;

ANTIPARKINSON AGENTS; CHALCONES; HELA CELLS; HUMANS; HYDROCARBONS, FLUORINATED; KINETICS; KYNURAMINE; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

EID: 84945907748 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2015.09.049 Document Type: Article

Times cited : (64)

References (49)

1
- 0043132076
- A.A. Baumeister, M.F. Hawkins, and S.M. Uzelac J. Hist. Neurosci. 12 2003 207
- (2003) J. Hist. Neurosci. , vol.12 , pp. 207
- Baumeister, A.A.¹ Hawkins, M.F.² Uzelac, S.M.³

2
- 69949161473
- C. Lanni, S. Govoni, A. Lucchelli, and C. Boselli Cell. Mol. Life Sci. 66 2009 2985
- (2009) Cell. Mol. Life Sci. , vol.66 , pp. 2985
- Lanni, C.¹ Govoni, S.² Lucchelli, A.³ Boselli, C.⁴

3
- 66949117423
- C.W. Olanow, M.B. Stern, and K. Sethi Neurology 72 2009 S1
- (2009) Neurology , vol.72 , pp. S1
- Olanow, C.W.¹ Stern, M.B.² Sethi, K.³

4
- 30444437749
- M.B. Youdim, and Y.S. Bakhle Br. J. Pharmacol. 147 2006 S287
- (2006) Br. J. Pharmacol. , vol.147 , pp. S287
- Youdim, M.B.¹ Bakhle, Y.S.²

5
- 33645307953
- M.B. Youdim, D. Edmondson, and K.F. Tipton Nat. Rev. Neurosci. 7 2006 295
- (2006) Nat. Rev. Neurosci. , vol.7 , pp. 295
- Youdim, M.B.¹ Edmondson, D.² Tipton, K.F.³

6
- 84902545188
- J.P. Finberg Pharmacol. Ther. 143 2014 133
- (2014) Pharmacol. Ther. , vol.143 , pp. 133
- Finberg, J.P.¹

7
- 0036231440
- I. Shoulson, D. Oakes, S. Fahn, A. Lang, J.W. Langston, P. LeWitt, C.W. Olanow, J.B. Penney, C. Tanner, K. Kieburtz, A. Rudolph Parkinson Study Group Ann. Neurol. 51 2002 604
- (2002) Ann. Neurol. , vol.51 , pp. 604
- Shoulson, I.¹ Oakes, D.² Fahn, S.³ Lang, A.⁴ Langston, J.W.⁵ LeWitt, P.⁶ Olanow, C.W.⁷ Penney, J.B.⁸ Tanner, C.⁹ Kieburtz, K.¹⁰ Rudolph, A.¹¹

8
- 36849055017
- H.H. Fernandez, and J.J. Chen Pharmacotherapy 27 2007 174S
- (2007) Pharmacotherapy , vol.27 , pp. 174S
- Fernandez, H.H.¹ Chen, J.J.²

9
- 0031596702
- J.P. Finberg, J. Wang, K. Bankiewicz, J. Harvey-White, I.J. Kopin, and D.S. Goldstein J. Neural Transm. Suppl. 52 1998 279
- (1998) J. Neural Transm. Suppl. , vol.52 , pp. 279
- Finberg, J.P.¹ Wang, J.² Bankiewicz, K.³ Harvey-White, J.⁴ Kopin, I.J.⁵ Goldstein, D.S.⁶

10
- 84893021427
- D.E. Edmondson Curr. Pharm. Des. 20 2014 155
- (2014) Curr. Pharm. Des. , vol.20 , pp. 155
- Edmondson, D.E.¹

11
- 0030768730
- J.S. Fowler, N.D. Volkow, G.J. Wang, J. Logan, N. Pappas, C. Shea, and R. MacGregor Neurobiol. Aging 18 1997 431
- (1997) Neurobiol. Aging , vol.18 , pp. 431
- Fowler, J.S.¹ Volkow, N.D.² Wang, G.J.³ Logan, J.⁴ Pappas, N.⁵ Shea, C.⁶ MacGregor, R.⁷

12
- 0037377592
- A. Maurel, C. Hernandez, O. Kunduzova, G. Bompart, C. Cambon, A. Parini, and B. Francés Am. J. Physiol. Heart Circ. Physiol. 284 2003 H1460
- (2003) Am. J. Physiol. Heart Circ. Physiol. , vol.284 , pp. H1460
- Maurel, A.¹ Hernandez, C.² Kunduzova, O.³ Bompart, G.⁴ Cambon, C.⁵ Parini, A.⁶ Francés, B.⁷

13
- 84901850631
- N. Kaludercic, J. Mialet-Perez, N. Paolocci, A. Parini, and F. Di Lisa J. Mol. Cell. Cardiol. 73 2014 34
- (2014) J. Mol. Cell. Cardiol. , vol.73 , pp. 34
- Kaludercic, N.¹ Mialet-Perez, J.² Paolocci, N.³ Parini, A.⁴ Di Lisa, F.⁵

14
- 65649087484
- F. Chimenti, R. Fioravanti, A. Bolasco, P. Chimenti, D. Secci, F. Rossi, M. Yáñez, F. Orallo, F. Ortuso, and S. Alcaro J. Med. Chem. 52 2009 2818
- (2009) J. Med. Chem. , vol.52 , pp. 2818
- Chimenti, F.¹ Fioravanti, R.² Bolasco, A.³ Chimenti, P.⁴ Secci, D.⁵ Rossi, F.⁶ Yáñez, M.⁷ Orallo, F.⁸ Ortuso, F.⁹ Alcaro, S.¹⁰

15
- 0023103019
- S. Tanaka, Y. Kuwai, and M. Tabata Planta Med. 53 1987 5
- (1987) Planta Med. , vol.53 , pp. 5
- Tanaka, S.¹ Kuwai, Y.² Tabata, M.³

16
- 4344678677
- H. Haraguchi, Y. Tanaka, A. Kabbash, T. Fujioka, T. Ishizu, and A. Yagi Phytochemistry 65 2004 2255
- (2004) Phytochemistry , vol.65 , pp. 2255
- Haraguchi, H.¹ Tanaka, Y.² Kabbash, A.³ Fujioka, T.⁴ Ishizu, T.⁵ Yagi, A.⁶

17
- 0033775140
- X. Pan, L.D. Kong, Y. Zhang, C.H. Cheng, and R.X. Tan Acta Pharmacol. Sin. 21 2000 949
- (2000) Acta Pharmacol. Sin. , vol.21 , pp. 949
- Pan, X.¹ Kong, L.D.² Zhang, Y.³ Cheng, C.H.⁴ Tan, R.X.⁵

18
- 0035960063
- G.Y. Gao, D.J. Li, and W.M. Keungm J. Med. Chem. 44 2001 3320
- (2001) J. Med. Chem. , vol.44 , pp. 3320
- Gao, G.Y.¹ Li, D.J.² Keungm, W.M.³

19
- 84929310167
- N. Morales-Camilo, C.O. Salas, C. Sanhueza, C. Espinosa-Bustos, S. Sepúlveda-Boza, M. Reyes-Parada, F. Gonzalez-Nilo, M. Caroli-Rezende, and A. Fierro Chem. Biol. Drug Des. 85 2015 685
- (2015) Chem. Biol. Drug Des. , vol.85 , pp. 685
- Morales-Camilo, N.¹ Salas, C.O.² Sanhueza, C.³ Espinosa-Bustos, C.⁴ Sepúlveda-Boza, S.⁵ Reyes-Parada, M.⁶ Gonzalez-Nilo, F.⁷ Caroli-Rezende, M.⁸ Fierro, A.⁹

20
- 84937955455
- B. Mathew, G.E. Mathew, G. Uçar, I. Baysal, J. Suresh, J.K. Vilapurathu, A. Prakasan, J.K. Suresh, and A. Thomas Bioorg. Chem. 62 2015 22
- (2015) Bioorg. Chem. , vol.62 , pp. 22
- Mathew, B.¹ Mathew, G.E.² Uçar, G.³ Baysal, I.⁴ Suresh, J.⁵ Vilapurathu, J.K.⁶ Prakasan, A.⁷ Suresh, J.K.⁸ Thomas, A.⁹

21
- 20144367578
- M.L. Go, X. Wu, and X.L. Liu Curr. Med. Chem. 12 2005 481
- (2005) Curr. Med. Chem. , vol.12 , pp. 481
- Go, M.L.¹ Wu, X.² Liu, X.L.³

22
- 0032724393
- J.R. Dimmock, D.W. Elias, M.A. Beazely, and N.M. Kandepu Curr. Med. Chem. 6 1999 1125
- (1999) Curr. Med. Chem. , vol.6 , pp. 1125
- Dimmock, J.R.¹ Elias, D.W.² Beazely, M.A.³ Kandepu, N.M.⁴

23
- 75149195318
- F. Chimenti, R. Fioravanti, A. Bolasco, P. Chimenti, D. Secci, F. Rossi, M. Yáñez, F. Orallo, F. Ortuso, S. Alcaro, R. Cirilli, R. Ferretti, and M.L. Sanna Bioorg. Med. Chem. 18 2010 1273
- (2010) Bioorg. Med. Chem. , vol.18 , pp. 1273
- Chimenti, F.¹ Fioravanti, R.² Bolasco, A.³ Chimenti, P.⁴ Secci, D.⁵ Rossi, F.⁶ Yáñez, M.⁷ Orallo, F.⁸ Ortuso, F.⁹ Alcaro, S.¹⁰ Cirilli, R.¹¹ Ferretti, R.¹² Sanna, M.L.¹³

24
- 73549097080
- F. Chimenti, S. Carradori, D. Secci, A. Bolasco, B. Bizzarri, P. Chimenti, A. Granese, M. Yáñez, and F. Orallo Eur. J. Med. Chem. 45 2010 800
- (2010) Eur. J. Med. Chem. , vol.45 , pp. 800
- Chimenti, F.¹ Carradori, S.² Secci, D.³ Bolasco, A.⁴ Bizzarri, B.⁵ Chimenti, P.⁶ Granese, A.⁷ Yáñez, M.⁸ Orallo, F.⁹

25
- 33846930800
- F. Chimenti, R. Fioravanti, A. Bolasco, F. Manna, P. Chimenti, D. Secci, O. Befani, P. Turini, F. Ortuso, and S. Alcaro J. Med. Chem. 50 2007 425
- (2007) J. Med. Chem. , vol.50 , pp. 425
- Chimenti, F.¹ Fioravanti, R.² Bolasco, A.³ Manna, F.⁴ Chimenti, P.⁵ Secci, D.⁶ Befani, O.⁷ Turini, P.⁸ Ortuso, F.⁹ Alcaro, S.¹⁰

26
- 28544443174
- F. Chimenti, E. Maccioni, D. Secci, A. Bolasco, P. Chimenti, A. Granese, O. Befani, P. Turini, S. Alcaro, F. Ortuso, R. Cirilli, F. La Torre, M.C. Cardia, and S. Distinto J. Med. Chem. 48 2005 7113
- (2005) J. Med. Chem. , vol.48 , pp. 7113
- Chimenti, F.¹ Maccioni, E.² Secci, D.³ Bolasco, A.⁴ Chimenti, P.⁵ Granese, A.⁶ Befani, O.⁷ Turini, P.⁸ Alcaro, S.⁹ Ortuso, F.¹⁰ Cirilli, R.¹¹ La Torre, F.¹² Cardia, M.C.¹³ Distinto, S.¹⁴

27
- 33645314648
- F. Chimenti, A. Bolasco, F. Manna, D. Secci, P. Chimenti, A. Granese, O. Befanim, P. Turini, S. Alcaro, and F. Ortuso Chem. Biol. Drug Des. 67 2006 206
- (2006) Chem. Biol. Drug Des. , vol.67 , pp. 206
- Chimenti, F.¹ Bolasco, A.² Manna, F.³ Secci, D.⁴ Chimenti, P.⁵ Granese, A.⁶ Befanim, O.⁷ Turini, P.⁸ Alcaro, S.⁹ Ortuso, F.¹⁰

28
- 58549107997
- N. Gökhan-Kelekçi, S. Koyunoʇlu, S. Yabanoʇlu, K. Yelekçi, O. Ozgen, G. Uçar, K. Erol, E. Kendi, and A. Yeşilada Bioorg. Med. Chem. 17 2009 675
- (2009) Bioorg. Med. Chem. , vol.17 , pp. 675
- Gökhan-Kelekçi, N.¹ Koyunoʇlu, S.² Yabanoʇlu, S.³ Yelekçi, K.⁴ Ozgen, O.⁵ Uçar, G.⁶ Erol, K.⁷ Kendi, E.⁸ Yeşilada, A.⁹

29
- 84874905503
- D. Secci, S. Carradori, A. Bolasco, B. Bizzarri, M. D'Ascenzio, and E. Maccioni Curr. Top. Med. Chem. 12 2012 2240
- (2012) Curr. Top. Med. Chem. , vol.12 , pp. 2240
- Secci, D.¹ Carradori, S.² Bolasco, A.³ Bizzarri, B.⁴ D'Ascenzio, M.⁵ Maccioni, E.⁶

30
- 84899736062
- B. Mathew, J. Suresh, S. Anbazhagan, and G.E. Mathew Cent. Nerv. Syst. Agents Med. Chem. 13 2013 195
- (2013) Cent. Nerv. Syst. Agents Med. Chem. , vol.13 , pp. 195
- Mathew, B.¹ Suresh, J.² Anbazhagan, S.³ Mathew, G.E.⁴

31
- 84881374009
- S.J. Robinson, J.P. Petzer, A. Petzer, J.J. Bergh, and A.C. Lourens Bioorg. Med. Chem. Lett. 23 2013 4985
- (2013) Bioorg. Med. Chem. Lett. , vol.23 , pp. 4985
- Robinson, S.J.¹ Petzer, J.P.² Petzer, A.³ Bergh, J.J.⁴ Lourens, A.C.⁵

32
- 84937133930
- S. Zaib, S.U. Farooq Rizvi, S. Aslam, M. Ahmad, M. Al-Rashida, and J. Iqbal Med. Chem. 11 2015 497
- (2015) Med. Chem. , vol.11 , pp. 497
- Zaib, S.¹ Farooq Rizvi, S.U.² Aslam, S.³ Ahmad, M.⁴ Al-Rashida, M.⁵ Iqbal, J.⁶

33
- 84938585218
- S. Zaib, S.U. Rizvi, S. Aslam, M. Ahmad, S.M. Ali Abid, M. Al-Rashida, and J. Iqbal Med. Chem. 11 2015 580
- (2015) Med. Chem. , vol.11 , pp. 580
- Zaib, S.¹ Rizvi, S.U.² Aslam, S.³ Ahmad, M.⁴ Ali Abid, S.M.⁵ Al-Rashida, M.⁶ Iqbal, J.⁷

34
- 0023797315
- M. Da Prada, G. Zürcher, I. Wüthrich, and W.E. Haefely J. Neural Transm. Suppl. 26 1988 31
- (1988) J. Neural Transm. Suppl. , vol.26 , pp. 31
- Da Prada, M.¹ Zürcher, G.² Wüthrich, I.³ Haefely, W.E.⁴

35
- 84864856634
- D.A. Flockhart J. Clin. Psychiatry 73 2012 17
- (2012) J. Clin. Psychiatry , vol.73 , pp. 17
- Flockhart, D.A.¹

36
- 0037361293
- U. Bonnet CNS Drug Rev. 9 2003 97
- (2003) CNS Drug Rev. , vol.9 , pp. 97
- Bonnet, U.¹

37
- 0026475165
- J.C. Provost, C. Funck-Brentano, V. Rovei, J. D'Estanque, D. Ego, and P. Jaillon Clin. Pharmacol. Ther. 52 1992 384
- (1992) Clin. Pharmacol. Ther. , vol.52 , pp. 384
- Provost, J.C.¹ Funck-Brentano, C.² Rovei, V.³ D'Estanque, J.⁴ Ego, D.⁵ Jaillon, P.⁶

38
- 84861828694
- C.U. Pae, J.A. Bodkin, K.B. Portland, M.E. Thase, and A.A. Patkar J. Clin. Psychiatry 73 2012 661
- (2012) J. Clin. Psychiatry , vol.73 , pp. 661
- Pae, C.U.¹ Bodkin, J.A.² Portland, K.B.³ Thase, M.E.⁴ Patkar, A.A.⁵

39
- 80053465129
- J.P. Finberg, and K. Gillman Int. Rev. Neurobiol. 100 2011 169
- (2011) Int. Rev. Neurobiol. , vol.100 , pp. 169
- Finberg, J.P.¹ Gillman, K.²

40
- 38949190283
- G. Cocconcelli, E. Diodato, A. Caricasole, G. Gaviraghi, E. Genesio, C. Ghiron, L. Magnoni, E. Pecchioli, P.V. Plazzi, and G.C. Terstappen Bioorg. Med. Chem. 16 2008 2043
- (2008) Bioorg. Med. Chem. , vol.16 , pp. 2043
- Cocconcelli, G.¹ Diodato, E.² Caricasole, A.³ Gaviraghi, G.⁴ Genesio, E.⁵ Ghiron, C.⁶ Magnoni, L.⁷ Pecchioli, E.⁸ Plazzi, P.V.⁹ Terstappen, G.C.¹⁰

41
- 25844509359
- L. Novaroli, M. Reist, E. Favre, A. Carotti, M. Catto, and P.A. Carrupt Bioorg. Med. Chem. 13 2005 6212
- (2005) Bioorg. Med. Chem. , vol.13 , pp. 6212
- Novaroli, L.¹ Reist, M.² Favre, E.³ Carotti, A.⁴ Catto, M.⁵ Carrupt, P.A.⁶

42
- 84928489545
- S. Mostert, A. Petzer, and J.P. Petzer ChemMedChem 10 2015 862
- (2015) ChemMedChem , vol.10 , pp. 862
- Mostert, S.¹ Petzer, A.² Petzer, J.P.³

43
- 84885040174
- A. Petzer, A. Pienaar, and J.P. Petzer Drug Res. (Stuttg) 63 2013 462
- (2013) Drug Res. (Stuttg) , vol.63 , pp. 462
- Petzer, A.¹ Pienaar, A.² Petzer, J.P.³

44
- 79960651250
- A. Gaspar, T. Silva, M. Yáñez, D. Vina, F. Orallo, F. Ortuso, E. Uriarte, S. Alcaro, and F. Borges J. Med. Chem. 54 2011 5165
- (2011) J. Med. Chem. , vol.54 , pp. 5165
- Gaspar, A.¹ Silva, T.² Yáñez, M.³ Vina, D.⁴ Orallo, F.⁵ Ortuso, F.⁶ Uriarte, E.⁷ Alcaro, S.⁸ Borges, F.⁹

45
- 78651257725
- A. Gaspar, J. Reis, A. Fonseca, N. Milhazes, D. Viña, E. Uriarte, and F. Borges Bioorg. Med. Chem. Lett. 21 2011 707
- (2011) Bioorg. Med. Chem. Lett. , vol.21 , pp. 707
- Gaspar, A.¹ Reis, J.² Fonseca, A.³ Milhazes, N.⁴ Viña, D.⁵ Uriarte, E.⁶ Borges, F.⁷

46
- 0028928880
- M.J. Krueger, F. Mazouz, R.R. Ramsay, R. Milcent, and T.P. Singer Biochem. Biophys. Res. Commun. 206 1995 556
- (1995) Biochem. Biophys. Res. Commun. , vol.206 , pp. 556
- Krueger, M.J.¹ Mazouz, F.² Ramsay, R.R.³ Milcent, R.⁴ Singer, T.P.⁵

47
- 0027175990
- F. Mazouz, S. Gueddari, C. Burstein, D. Mansuy, and R. Milcent J. Med. Chem. 36 1993 1157
- (1993) J. Med. Chem. , vol.36 , pp. 1157
- Mazouz, F.¹ Gueddari, S.² Burstein, C.³ Mansuy, D.⁴ Milcent, R.⁵

48
- 0021061819
- T. Mosmann J. Immunol. Methods 65 1983 55
- (1983) J. Immunol. Methods , vol.65 , pp. 55
- Mosmann, T.¹

49
- 84908407321
- A. Delport, B.H. Harvey, A. Petzer, and J.P. Petzer Life Sci. 117 2014 56
- (2014) Life Sci. , vol.117 , pp. 56
- Delport, A.¹ Harvey, B.H.² Petzer, A.³ Petzer, J.P.⁴

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