Monoamine oxidase inhibition and molecular modeling studies of piperidyl-thienyl and 2-pyrazoline derivatives of chalcones

Medicinal Chemistry

Volumn 11, Issue 5, 2015, Pages 497-505

  Zaib, Sumera ^a   Rizvi, Syed Umar Farooq ^b   Aslam, Sana ^b,c   Ahmad, Matloob ^d   Al Rashida, Mariya ^e   Iqbal, Jamshed ^a  

^a COMSATS Institute of Information Technology ^*  (Pakistan)

^b UNIVERSITY OF THE PUNJAB   (Pakistan)

^c GOVERNMENT COLLEGE WOMEN UNIVERSITY   (Pakistan)

^d GOVERNMENT COLLEGE UNIVERSITY   (Pakistan)

^e FORMAN CHRISTIAN COLLEGE A CHARTERED UNIVERSITY   (Pakistan)

Author keywords

Antidepressant activity; Molecular docking; Monoamine oxidase; Piperidyl thienyl derivatives; Quinolyl thienyl chalcones

Indexed keywords

2 PYRAZOLINE DERIVATIVE; AMINE OXIDASE (FLAVIN CONTAINING); AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; CHALCONE DERIVATIVE; CLORGYLINE; MONOAMINE OXIDASE INHIBITOR; PIPERIDYL THIENYL DERIVATIVE; SELEGILINE; UNCLASSIFIED DRUG; PIPERIDINE DERIVATIVE; THIAZOLE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME INHIBITION; MOLECULAR MODEL; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; ENZYME ACTIVATION; HUMAN; IC50; RABBIT; SYNTHESIS;

ANIMALS; BINDING SITES; CHALCONES; ENZYME ACTIVATION; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MONOAMINE OXIDASE INHIBITORS; PIPERIDINES; RABBITS; THIAZOLES;

EID: 84937133930     PISSN: 15734064     EISSN: 18756638     Source Type: Journal    
DOI: 10.2174/1573406410666141229101130     Document Type: Article

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