Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors

Journal of Medicinal Chemistry

Volumn 54, Issue 14, 2011, Pages 5165-5173

  Gaspar, Alexandra ^a,b   Silva, Tiago ^a   Yáñez, Matilde ^b   Vina, Dolores ^b   Orallo, Franscisco ^b   Ortuso, Francesco ^b   Uriarte, Eugenio ^b   Alcaro, Stefano ^c   Borges, Fernanda ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^c UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4 PYRONE DERIVATIVE; AMINE OXIDASE (FLAVIN CONTAINING); AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; CHROMONE 3 CARBOXAMIDE; CHROMONE DERIVATIVE; ISATIN; MONOAMINE OXIDASE B INHIBITOR; MONOAMINE OXIDASE INHIBITOR; N (3,4 DIHYDROXYPHENYL) 4 OXO 4H 1 BENZOPYRAN 2 CARBOXAMIDE; N (3,4 DIHYDROXYPHENYL) 4 OXO 4H 1 BENZOPYRAN 3 CARBOXAMIDE; N (4 NITROPHENYL) 4 OXO 4H 1 BENZOPYRAN 2 CARBOXAMIDE; N (4 NITROPHENYL) 4 OXO 4H 1 BENZOPYRAN 3 CARBOXAMIDE; N CYCLOHEXYL 4 OXO 4H 1 BENZOPYRAN 2 CARBOXAMIDE; N CYCLOHEXYL 4 OXO 4H 1 BENZOPYRAN 3 CARBOXAMIDE; N PROPYL 4 OXO 4H 1 BENZOPYRAN 2 CARBOXAMIDE; N PROPYL 4 OXO 4H 1 BENZOPYRAN 3 CARBOXAMIDE; SELEGILINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; HUMAN; IC 50; ISOMER; NONHUMAN; SOLVATION; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

AMIDES; CHROMONES; HUMANS; ISOENZYMES; MODELS, MOLECULAR; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; WATER;

EID: 79960651250     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm2004267     Document Type: Article

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