High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant

Oncotarget

Volumn 6, Issue 31, 2015, Pages 30472-30486

  Farnie, Gillian ^a   Sotgia, Federica ^a,b   Lisanti, Michael P ^a,b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Cancer stem cells; Mitochondria; Mitotracker; Tumor metabolism

Indexed keywords

ALDEHYDE DEHYDROGENASE; PACLITAXEL; ANTINEOPLASTIC AGENT; CD24 ANTIGEN; CD24 PROTEIN, HUMAN; CELL ADHESION MOLECULE; EPITHELIAL CELL ADHESION MOLECULE; TUMOR ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; BREAST CELL; CANCER STEM CELL; CANCER STEM LIKE CELL; CANCER TISSUE; CELL FRACTIONATION; CELL POPULATION; CELL SIZE; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DRUG RESISTANCE; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; METASTASIS; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NONHUMAN; PHENOTYPE; TUMOR XENOGRAFT; ANIMAL; BREAST TUMOR; CANCER TRANSPLANTATION; DRUG EFFECTS; FEMALE; GENETICS; MCF-7 CELL LINE; METABOLISM; MULTICELLULAR SPHEROID; NONOBESE DIABETIC MOUSE; PATHOLOGY; PHYSIOLOGY; SCID MOUSE; TUMOR CELL CULTURE; XENOGRAFT;

ALDEHYDE DEHYDROGENASE; ANIMALS; ANTIGENS, CD24; ANTIGENS, NEOPLASM; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; CELL ADHESION MOLECULES; COMET ASSAY; DNA DAMAGE; DRUG RESISTANCE, NEOPLASM; EPITHELIAL CELL ADHESION MOLECULE; FEMALE; FLOW CYTOMETRY; HUMANS; MCF-7 CELLS; MICE; MICE, INBRED NOD; MICE, SCID; MITOCHONDRIA; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; PACLITAXEL; SPHEROIDS, CELLULAR; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 84945543398     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5401     Document Type: Article

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