메뉴 건너뛰기




Volumn 5, Issue 12, 2014, Pages 4305-4319

Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation

Author keywords

Cancer stem cells; Glucose; Metabolism; Ovarian cancer; Warburg effect

Indexed keywords

6 PHOSPHOFRUCTOKINASE; CITRATE SYNTHASE; CITRININ; CYTOKERATIN 7; DEOXYGLUCOSE; DOXORUBICIN; FATTY ACID; GLUCOSE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUCOSE TRANSPORTER 1; HERMES ANTIGEN; HEXOKINASE; HEXOKINASE ISOENZYME; ISOCITRATE DEHYDROGENASE; METFORMIN; MONOCARBOXYLATE TRANSPORTER 4; OLIGOMYCIN; PENTOSE PHOSPHATE; PRASTERONE; PYRUVATE DEHYDROGENASE; PYRUVATE KINASE; REACTIVE OXYGEN METABOLITE; RIBULOSE PHOSPHATE; ROTENONE; STEM CELL FACTOR RECEPTOR; TRICARBOXYLIC ACID; UNCLASSIFIED DRUG;

EID: 84905118703     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2010     Document Type: Article
Times cited : (234)

References (46)
  • 1
    • 79955398591 scopus 로고    scopus 로고
    • Otto Warburg's contributions to current concepts of cancer metabolism
    • Koppenol WH, Bounds PL and Dang CV. Otto Warburg's contributions to current concepts of cancer metabolism. Nat Rev Cancer. 2011; 11(5):325-337.
    • (2011) Nat Rev Cancer , vol.11 , Issue.5 , pp. 325-337
    • Koppenol, W.H.1    Bounds, P.L.2    Dang, C.V.3
  • 2
    • 84858608410 scopus 로고    scopus 로고
    • Cancer stem cells: impact, heterogeneity, and uncertainty
    • Magee JA, Piskounova E and Morrison SJ. Cancer stem cells: impact, heterogeneity, and uncertainty. Cancer Cell. 2012; 21(3):283-296.
    • (2012) Cancer Cell , vol.21 , Issue.3 , pp. 283-296
    • Magee, J.A.1    Piskounova, E.2    Morrison, S.J.3
  • 5
    • 79952370202 scopus 로고    scopus 로고
    • The cancer stem cell: premises, promises and challenges
    • Clevers H. The cancer stem cell: premises, promises and challenges. Nat Med. 2011; 17(3):313-319.
    • (2011) Nat Med , vol.17 , Issue.3 , pp. 313-319
    • Clevers, H.1
  • 7
    • 84875419233 scopus 로고    scopus 로고
    • Meeting the challenge of ascites in ovarian cancer: new avenues for therapy and research
    • Kipps E, Tan DS and Kaye SB. Meeting the challenge of ascites in ovarian cancer: new avenues for therapy and research. Nat Rev Cancer. 2013; 13(4):273-282.
    • (2013) Nat Rev Cancer , vol.13 , Issue.4 , pp. 273-282
    • Kipps, E.1    Tan, D.S.2    Kaye, S.B.3
  • 8
    • 84874462054 scopus 로고    scopus 로고
    • Cancer metabolism: key players in metabolic reprogramming
    • Soga T. Cancer metabolism: key players in metabolic reprogramming. Cancer Sci. 2013; 104(3):275-281.
    • (2013) Cancer Sci , vol.104 , Issue.3 , pp. 275-281
    • Soga, T.1
  • 9
    • 84858604270 scopus 로고    scopus 로고
    • Metabolic reprogramming: a cancer hallmark even warburg did not anticipate
    • Ward PS and Thompson CB. Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer Cell. 2012; 21(3):297-308.
    • (2012) Cancer Cell , vol.21 , Issue.3 , pp. 297-308
    • Ward, P.S.1    Thompson, C.B.2
  • 11
    • 17144403478 scopus 로고    scopus 로고
    • Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer
    • Bapat SA, Mali AM, Koppikar CB and Kurrey NK. Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer. Cancer Res. 2005; 65(8):3025-3029.
    • (2005) Cancer Res , vol.65 , Issue.8 , pp. 3025-3029
    • Bapat, S.A.1    Mali, A.M.2    Koppikar, C.B.3    Kurrey, N.K.4
  • 13
    • 70349859809 scopus 로고    scopus 로고
    • Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells
    • Kurrey NK, Jalgaonkar SP, Joglekar AV, Ghanate AD, Chaskar PD, Doiphode RY and Bapat SA. Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells. Stem Cells. 2009; 27(9):2059-2068.
    • (2009) Stem Cells , vol.27 , Issue.9 , pp. 2059-2068
    • Kurrey, N.K.1    Jalgaonkar, S.P.2    Joglekar, A.V.3    Ghanate, A.D.4    Chaskar, P.D.5    Doiphode, R.Y.6    Bapat, S.A.7
  • 15
    • 65949112714 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis
    • Huang EH, Hynes MJ, Zhang T, Ginestier C, Dontu G, Appelman H, Fields JZ, Wicha MS and Boman BM. Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res. 2009; 69(8):3382-3389.
    • (2009) Cancer Res , vol.69 , Issue.8 , pp. 3382-3389
    • Huang, E.H.1    Hynes, M.J.2    Zhang, T.3    Ginestier, C.4    Dontu, G.5    Appelman, H.6    Fields, J.Z.7    Wicha, M.S.8    Boman, B.M.9
  • 16
    • 61449178983 scopus 로고    scopus 로고
    • An essential role for the Glut1 PDZ-binding motif in growth factor regulation of Glut1 degradation and trafficking
    • Wieman HL, Horn SR, Jacobs SR, Altman BJ, Kornbluth S and Rathmell JC. An essential role for the Glut1 PDZ-binding motif in growth factor regulation of Glut1 degradation and trafficking. Biochem J. 2009; 418(2):345-367.
    • (2009) Biochem J , vol.418 , Issue.2 , pp. 345-367
    • Wieman, H.L.1    Horn, S.R.2    Jacobs, S.R.3    Altman, B.J.4    Kornbluth, S.5    Rathmell, J.C.6
  • 19
    • 79955601028 scopus 로고    scopus 로고
    • Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells
    • Pike LS, Smift AL, Croteau NJ, Ferrick DA and Wu M. Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells. Biochim Biophys Acta. 2011; 1807(6):726-734.
    • (2011) Biochim Biophys Acta , vol.1807 , Issue.6 , pp. 726-734
    • Pike, L.S.1    Smift, A.L.2    Croteau, N.J.3    Ferrick, D.A.4    Wu, M.5
  • 21
    • 84874889081 scopus 로고    scopus 로고
    • PKM2, a Central Point of Regulation in Cancer Metabolism
    • Wong N, De Melo J and Tang D. PKM2, a Central Point of Regulation in Cancer Metabolism. Int J Cell Biol. 2013; 2013:242513.
    • (2013) Int J Cell Biol. , vol.2013 , pp. 242513
    • Wong, N.1    De Melo, J.2    Tang, D.3
  • 22
    • 78549233413 scopus 로고    scopus 로고
    • Turning on a fuel switch of cancer: hnRNP proteins regulate alternative splicing of pyruvate kinase mRNA
    • Chen M, Zhang J and Manley JL. Turning on a fuel switch of cancer: hnRNP proteins regulate alternative splicing of pyruvate kinase mRNA. Cancer Res. 2010; 70(22):8977-8980.
    • (2010) Cancer Res , vol.70 , Issue.22 , pp. 8977-8980
    • Chen, M.1    Zhang, J.2    Manley, J.L.3
  • 23
    • 5444224643 scopus 로고    scopus 로고
    • Efficacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues
    • Pendergrass W, Wolf N and Poot M. Efficacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues. Cytometry A. 2004; 61(2):162-169.
    • (2004) Cytometry A , vol.61 , Issue.2 , pp. 162-169
    • Pendergrass, W.1    Wolf, N.2    Poot, M.3
  • 25
    • 0034176843 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts
    • Nicholls DG and Ward MW. Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts. Trends Neurosci. 2000; 23(4):166-174.
    • (2000) Trends Neurosci , vol.23 , Issue.4 , pp. 166-174
    • Nicholls, D.G.1    Ward, M.W.2
  • 26
    • 0034614420 scopus 로고    scopus 로고
    • Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I
    • El-Mir MY, Nogueira V, Fontaine E, Avéret N, Rigoulet M and Leverve X. Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I. J Biol Chem. 2000; 275(1):223-228.
    • (2000) J Biol Chem , vol.275 , Issue.1 , pp. 223-228
    • El-Mir, M.Y.1    Nogueira, V.2    Fontaine, E.3    Avéret, N.4    Rigoulet, M.5    Leverve, X.6
  • 32
    • 80053925452 scopus 로고    scopus 로고
    • Not so lonely at the top for cancer stem cells
    • Zeuner A and De Maria R. Not so lonely at the top for cancer stem cells. Cell Stem Cell. 2011; 9(4):289-290.
    • (2011) Cell Stem Cell , vol.9 , Issue.4 , pp. 289-290
    • Zeuner, A.1    De Maria, R.2
  • 33
    • 85039611684 scopus 로고    scopus 로고
    • M(o)TOR of pseudo-hypoxic state in aging: rapamycin to the rescue
    • Leontieva OV and Blagosklonny MV. (2014). M(o)TOR of pseudo-hypoxic state in aging: rapamycin to the rescue.
    • (2014)
    • Leontieva, O.V.1    Blagosklonny, M.V.2
  • 34
    • 84897973068 scopus 로고    scopus 로고
    • Gerometabolites: the pseudohypoxic aging side of cancer oncometabolites
    • Menendez JA, Alarcon T and Joven J. Gerometabolites: the pseudohypoxic aging side of cancer oncometabolites. Cell Cycle. 2014; 13(5):699-709.
    • (2014) Cell Cycle , vol.13 , Issue.5 , pp. 699-709
    • Menendez, J.A.1    Alarcon, T.2    Joven, J.3
  • 37
    • 84867140008 scopus 로고    scopus 로고
    • Emerging roles of PKM2 in cell metabolism and cancer progression
    • Luo W and Semenza GL. Emerging roles of PKM2 in cell metabolism and cancer progression. Trends Endocrinol Metab. 2012; 23(11):560-566.
    • (2012) Trends Endocrinol Metab , vol.23 , Issue.11 , pp. 560-566
    • Luo, W.1    Semenza, G.L.2
  • 40
    • 80052627393 scopus 로고    scopus 로고
    • Mitochondrial permeability transition in Ca(2+)-dependent apoptosis and necrosis
    • Rasola A and Bernardi P. Mitochondrial permeability transition in Ca(2+)-dependent apoptosis and necrosis. Cell Calcium. 2011; 50(3):222-233.
    • (2011) Cell Calcium , vol.50 , Issue.3 , pp. 222-233
    • Rasola, A.1    Bernardi, P.2
  • 42
    • 84857450316 scopus 로고    scopus 로고
    • Metabolic effects of anti-angiogenic therapy in tumors
    • Zulato E, Curtarello M, Nardo G and Indraccolo S. Metabolic effects of anti-angiogenic therapy in tumors. Biochimie. 2012; 94(4):925-931.
    • (2012) Biochimie , vol.94 , Issue.4 , pp. 925-931
    • Zulato, E.1    Curtarello, M.2    Nardo, G.3    Indraccolo, S.4
  • 43
    • 70350225829 scopus 로고    scopus 로고
    • The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
    • Heddleston JM, Li Z, McLendon RE, Hjelmeland AB and Rich JN. The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. Cell Cycle. 2009; 8(20):3274-3284.
    • (2009) Cell Cycle , vol.8 , Issue.20 , pp. 3274-3284
    • Heddleston, J.M.1    Li, Z.2    McLendon, R.E.3    Hjelmeland, A.B.4    Rich, J.N.5
  • 45
    • 77955868246 scopus 로고    scopus 로고
    • Redox regulation of T-cell turnover by the p13 protein of human T-cell leukemia virus type 1: distinct effects in primary versus transformed cells
    • Silic-Benussi M, Cavallari I, Vajente N, Vidali S, Chieco-Bianchi L, Di Lisa F, Saggioro D, D'Agostino DM and Ciminale V. Redox regulation of T-cell turnover by the p13 protein of human T-cell leukemia virus type 1: distinct effects in primary versus transformed cells. Blood. 2010; 116(1):54-62.
    • (2010) Blood , vol.116 , Issue.1 , pp. 54-62
    • Silic-Benussi, M.1    Cavallari, I.2    Vajente, N.3    Vidali, S.4    Chieco-Bianchi, L.5    Di Lisa, F.6    Saggioro, D.7    D'Agostino, D.M.8    Ciminale, V.9
  • 46
    • 0035969097 scopus 로고    scopus 로고
    • Transcriptional regulation in acute promyelocytic leukemia
    • Lin RJ, Sternsdorf T, Tini M and Evans RM. Transcriptional regulation in acute promyelocytic leukemia. Oncogene. 2001; 20(49):7204-7215.
    • (2001) Oncogene , vol.20 , Issue.49 , pp. 7204-7215
    • Lin, R.J.1    Sternsdorf, T.2    Tini, M.3    Evans, R.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.