Focal adhesion kinase and wnt signaling regulate human ductal carcinoma in situ stem cell activity and response to radiotherapy

Stem Cells

Volumn 33, Issue 2, 2015, Pages 327-341

  Williams, Kathryn E ^a,b   Bundred, Nigel J ^a   Landberg, Göran ^c   Clarke, Robert B ^b   Farnie, Gillian ^b  

^a WYTHENSHAWE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Breast; Cancer stem cells; Focal adhesion kinase; Radiotherapy; Spheres; Wnt

Indexed keywords

BETA CATENIN; FOCAL ADHESION KINASE; MATRIGEL; PF 562271; SMALL INTERFERING RNA; FOCAL ADHESION KINASE 1; PTK2 PROTEIN, HUMAN; TUMOR PROTEIN; WNT3A PROTEIN; WNT3A PROTEIN, HUMAN;

ARTICLE; CANCER CELL LINE; CANCER DIAGNOSIS; CANCER GROWTH; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STEM CELL; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INTRADUCTAL CARCINOMA; MAJOR CLINICAL STUDY; WNT SIGNALING PATHWAY; ANIMAL; ANTAGONISTS AND INHIBITORS; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; METABOLISM; MOUSE; NUDE MOUSE; PATHOLOGY; RADIATION DOSE; RADIATION RESPONSE; TUMOR CELL LINE;

ANIMALS; BETA CATENIN; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CELL LINE, TUMOR; FEMALE; FOCAL ADHESION KINASE 1; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; MICE, NUDE; NEOPLASM PROTEINS; NEOPLASTIC STEM CELLS; RADIATION TOLERANCE; RNA, SMALL INTERFERING; WNT SIGNALING PATHWAY; WNT3A PROTEIN;

EID: 84921662176     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1843     Document Type: Article

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