MiR-21 modulates the immunoregulatory function of bone marrow mesenchymal stem cells through the PTEN/Akt/TGF-β1 pathway

Stem Cells

Volumn 33, Issue 11, 2015, Pages 3281-3290

  Wu, Tingting ^a   Liu, Yi ^a   Fan, Zhipeng ^a   Xu, Junji ^a   Jin, Luyuan ^a   Gao, Zhenhua ^a   Wu, Zhifang ^a   Hu, Lei ^a   Wang, Jinsong ^a   Zhang, Chunmei ^a   Chen, Wanjun ^b   Wang, Songlin ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

Immunoregulation; Mesenchymal stem cells; miR 21; PTEN; Transforming growth factor 1

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA 21; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1; MICRORNA; MIRN21 MICRORNA, MOUSE; PTEN PROTEIN, MOUSE;

ADOPTIVE TRANSFER; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; EXPERIMENTAL COLITIS; HUMAN; HUMAN CELL; IMMUNOREGULATION; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; NORMAL HUMAN; PROTEIN EXPRESSION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BONE MARROW CELL; C57BL MOUSE; CELL CULTURE; KNOCKOUT MOUSE; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; BONE MARROW CELLS; CELLS, CULTURED; HUMANS; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRORNAS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84945475205     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2081     Document Type: Article

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