Human skeletal myotubes display a cell-autonomous circadian clock implicated in basal myokine secretion

Molecular Metabolism

Volumn 4, Issue 11, 2015, Pages 834-845

  Perrin, Laurent ^a   Loizides Mangold, Ursula ^a   Skarupelova, Svetlana ^a   Pulimeno, Pamela ^a   Chanon, Stephanie ^b   Robert, Maud ^c   Bouzakri, Karim ^a   Modoux, Christine ^d   Roux Lombard, Pascale ^d   Vidal, Hubert ^b   Lefai, Etienne ^b   Dibner, Charna ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b UNIVERSITÉ LYON 1   (France)

^c EDOUARD HERRIOT HOSPITAL   (France)

^d GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Circadian bioluminescence recording; Circadian clock; Human skeletal myotube; Interleukin 6; Myokine

Indexed keywords

COLONY STIMULATING FACTOR 1; CRYPTOCHROME; CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 8; LENTIVIRUS VECTOR; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; MYOKINE; NUCLEAR RECEPTOR NR1D1; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR ARNTL; TRANSCRIPTION FACTOR CLOCK; UNCLASSIFIED DRUG; VASCULOTROPIN;

ADULT; AGED; ARTICLE; BIOLOGICAL MODEL; BIOLUMINESCENCE; BMAL1 GENE; CELL AUTONOMOUS CIRCADIAN CLOCK; CIRCADIAN RHYTHM; CONTROLLED STUDY; CRY1 GENE; CYTOKINE RELEASE; DOWN REGULATION; FEMALE; GENE DELIVERY SYSTEM; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MIDDLE AGED; MOLECULAR DYNAMICS; MUSCLE CELL; MYOTUBE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; REV ERB ALPHA GENE; SKELETAL MYOTUBE; VALIDATION PROCESS; VERY ELDERLY; YOUNG ADULT;

EID: 84945463226     PISSN: None     EISSN: 22128778     Source Type: Journal    
DOI: 10.1016/j.molmet.2015.07.009     Document Type: Article

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