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Volumn 306, Issue 7, 2014, Pages

Effect of IL-6 on the insulin sensitivity in patients with type 2 diabetes

Author keywords

Biopsy; Clamp technique; Humans; Inflammation; Insulin resistance; Interleukin 6; Metabolism; Muscle; Signal transducer and activator of transcription 3; Skeletal

Indexed keywords

CARBON DIOXIDE; GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; HYDROCORTISONE; INTERLEUKIN 6; NEUTRAL INSULIN; PLACEBO; RECOMBINANT INTERLEUKIN 6; STABLE ISOTOPE; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3;

EID: 84900546488     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00571.2013     Document Type: Article
Times cited : (37)

References (42)
  • 1
    • 33751501694 scopus 로고    scopus 로고
    • Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle
    • Al-Khalili L, Bouzakri K, Glund S, Lonnqvist F, Koistinen HA, Krook A. Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle. Mol Endocrinol 20: 3364-3375, 2006.
    • (2006) Mol Endocrinol , vol.20 , pp. 3364-3375
    • Al-Khalili, L.1    Bouzakri, K.2    Glund, S.3    Lonnqvist, F.4    Koistinen, H.A.5    Krook, A.6
  • 2
    • 57749093663 scopus 로고    scopus 로고
    • Sick fat, metabolic disease, atherosclerosis
    • Bays HE. "Sick fat, " metabolic disease, atherosclerosis. Am J Med 122: S26-S37, 2009.
    • (2009) Am J Med , vol.122
    • Bays, H.E.1
  • 3
    • 0001213072 scopus 로고
    • Muscle electrolytes in man determined by neutron activation analysis on needle biopsy specimens
    • Bergstrom J. Muscle electrolytes in man determined by neutron activation analysis on needle biopsy specimens. SJCLA 0036-5513 1962.
    • (1962) SJCLA , pp. 0036-5513
    • Bergstrom, J.1
  • 6
    • 84866278132 scopus 로고    scopus 로고
    • Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic beta-cell line and mouse islets
    • da Silva KM, Bittencourt A, Homem de Bittencourt PI Jr, McClenaghan NH, Flatt PR, Murphy C, Newsholme P. Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic beta-cell line and mouse islets. J Endocrinol 214: 301-311, 2012.
    • (2012) J Endocrinol , vol.214 , pp. 301-311
    • da Silva, K.M.1    Bittencourt, A.2    de Bittencourt Homem Jr., P.I.3    McClenaghan, N.H.4    Flatt, P.R.5    Murphy, C.6    Newsholme, P.7
  • 8
    • 3042721664 scopus 로고    scopus 로고
    • Interleukin-6 is a novel factor mediating glucose homeostasis during skeletal muscle contraction
    • Febbraio MA, Hiscock N, Sacchetti M, Fischer CP, Pedersen BK. Interleukin-6 is a novel factor mediating glucose homeostasis during skeletal muscle contraction. Diabetes 53: 1643-1648, 2004.
    • (2004) Diabetes , vol.53 , pp. 1643-1648
    • Febbraio, M.A.1    Hiscock, N.2    Sacchetti, M.3    Fischer, C.P.4    Pedersen, B.K.5
  • 9
    • 33947529793 scopus 로고    scopus 로고
    • Interleukin-6 in acute exercise and training: What is the biological relevance?
    • Fischer CP. Interleukin-6 in acute exercise and training: what is the biological relevance? Exerc Immunol Rev 12: 6-33, 2006.
    • (2006) Exerc Immunol Rev , vol.12 , pp. 6-33
    • Fischer, C.P.1
  • 15
    • 84872375286 scopus 로고    scopus 로고
    • Interleukin-6 promotes myogenic differentiation of mouse skeletal muscle cells: Role of the STAT3 pathway
    • Hoene M, Runge H, Haring HU, Schleicher ED, Weigert C. Interleukin-6 promotes myogenic differentiation of mouse skeletal muscle cells: role of the STAT3 pathway. Am J Physiol Cell Physiol 304: C128-C136, 2013.
    • (2013) Am J Physiol Cell Physiol , vol.304
    • Hoene, M.1    Runge, H.2    Haring, H.U.3    Schleicher, E.D.4    Weigert, C.5
  • 17
    • 0021211623 scopus 로고
    • The heterogeneity of gastric inhibitory polypeptide in porcine and human gastrointestinal mucosa evaluated with five different antisera
    • Krarup T, Holst JJ. The heterogeneity of gastric inhibitory polypeptide in porcine and human gastrointestinal mucosa evaluated with five different antisera. Regul Pept 9: 35-46, 1984.
    • (1984) Regul Pept , vol.9 , pp. 35-46
    • Krarup, T.1    Holst, J.J.2
  • 19
    • 58149345626 scopus 로고    scopus 로고
    • Dual role of interleukin-6 in regulating insulin sensitivity in murine skeletal muscle
    • Nieto-Vazquez I, Fernandez-Veledo S, de AC, Lorenzo M. Dual role of interleukin-6 in regulating insulin sensitivity in murine skeletal muscle. Diabetes 57: 3211-3221, 2008.
    • (2008) Diabetes , vol.57 , pp. 3211-3221
    • Nieto-Vazquez, I.1    Fernandez-Veledo, S.2    de, A.C.3    Lorenzo, M.4
  • 20
    • 80054963118 scopus 로고    scopus 로고
    • Proteomic identification of secreted proteins from human skeletal muscle cells and expression in response to strength training
    • Norheim F, Raastad T, Thiede B, Rustan AC, Drevon CA, Haugen F. Proteomic identification of secreted proteins from human skeletal muscle cells and expression in response to strength training. Am J Physiol Endocrinol Metab 301: E1013-E1021, 2011.
    • (2011) Am J Physiol Endocrinol Metab , vol.301
    • Norheim, F.1    Raastad, T.2    Thiede, B.3    Rustan, A.C.4    Drevon, C.A.5    Haugen, F.6
  • 22
    • 0028281773 scopus 로고
    • Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans
    • Orskov C, Rabenhoj L, Wettergren A, Kofod H, Holst JJ. Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans. Diabetes 43: 535-539, 1994.
    • (1994) Diabetes , vol.43 , pp. 535-539
    • Orskov, C.1    Rabenhoj, L.2    Wettergren, A.3    Kofod, H.4    Holst, J.J.5
  • 24
    • 71249157791 scopus 로고    scopus 로고
    • The diseasome of physical inactivity-and the role of myokines in muscle-fat cross talk
    • Pedersen BK. The diseasome of physical inactivity-and the role of myokines in muscle-fat cross talk. J Physiol 587: 5559-5568, 2009.
    • (2009) J Physiol , vol.587 , pp. 5559-5568
    • Pedersen, B.K.1
  • 26
    • 25844456730 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation
    • Plomgaard P, Bouzakri K, Krogh-Madsen R, Mittendorfer B, Zierath JR, Pedersen BK. Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation. Diabetes 54: 2939-2945, 2005.
    • (2005) Diabetes , vol.54 , pp. 2939-2945
    • Plomgaard, P.1    Bouzakri, K.2    Krogh-Madsen, R.3    Mittendorfer, B.4    Zierath, J.R.5    Pedersen, B.K.6
  • 28
    • 0345700727 scopus 로고    scopus 로고
    • Inflammatory cytokines and the risk to develop type 2 diabetes: Results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study
    • Spranger J, Kroke A, Mohlig M, Hoffmann K, Bergmann MM, Ristow M, Boeing H, Pfeiffer AF. Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Diabetes 52: 812-817, 2003.
    • (2003) Diabetes , vol.52 , pp. 812-817
    • Spranger, J.1    Kroke, A.2    Mohlig, M.3    Hoffmann, K.4    Bergmann, M.M.5    Ristow, M.6    Boeing, H.7    Pfeiffer, A.F.8
  • 31
    • 0034668926 scopus 로고    scopus 로고
    • Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6
    • Steensberg A, van HG, Osada T, Sacchetti M, Saltin B, Klarlund PB. Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6. J Physiol 529: 237-242, 2000.
    • (2000) J Physiol , vol.529 , pp. 237-242
    • Steensberg, A.1    van, H.G.2    Osada, T.3    Sacchetti, M.4    Saltin, B.5    Klarlund, P.B.6
  • 32
    • 0028674174 scopus 로고
    • Endocrine and carbohydrate responses to interleukin-6 in vivo
    • Stith RD, Luo J. Endocrine and carbohydrate responses to interleukin-6 in vivo. Circ Shock 44: 210-215, 1994.
    • (1994) Circ Shock , vol.44 , pp. 210-215
    • Stith, R.D.1    Luo, J.2
  • 37
    • 47549119091 scopus 로고    scopus 로고
    • Interleukin-6 markedly decreases skeletal muscle protein turnover and increases nonmuscle amino acid utilization in healthy individuals
    • van HG, Steensberg A, Fischer C, Keller C, Moller K, Moseley P, Pedersen BK. Interleukin-6 markedly decreases skeletal muscle protein turnover and increases nonmuscle amino acid utilization in healthy individuals. J Clin Endocrinol Metab 93: 2851-2858, 2008.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 2851-2858
    • van, H.G.1    Steensberg, A.2    Fischer, C.3    Keller, C.4    Moller, K.5    Moseley, P.6    Pedersen, B.K.7
  • 42
    • 65549128076 scopus 로고    scopus 로고
    • Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor-alpha expression
    • Yuen DY, Dwyer RM, Matthews VB, Zhang L, Drew BG, Neill B, Kingwell BA, Clark MG, Rattigan S, Febbraio MA. Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor-alpha expression. Diabetes 58: 1086-1095, 2009.
    • (2009) Diabetes , vol.58 , pp. 1086-1095
    • Yuen, D.Y.1    Dwyer, R.M.2    Matthews, V.B.3    Zhang, L.4    Drew, B.G.5    Neill, B.6    Kingwell, B.A.7    Clark, M.G.8    Rattigan, S.9    Febbraio, M.A.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.