The receptor CD44 is associated with systemic insulin resistance and proinflammatory macrophages in human adipose tissue

Diabetologia

Volumn 58, Issue 7, 2015, Pages 1579-1586

  Liu, Li Fen ^a   Kodama, Keiichi ^a,b   Wei, Ke ^a   Tolentino, Lorna L ^a   Choi, Okmi ^a   Engleman, Edgar G ^a   Butte, Atul J ^a,b   McLaughlin, Tracey ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LUCILE PACKARD CHILDREN S HOSPITAL   (United States)

Author keywords

Adipose tissue macrophage; Alternatively activated macrophage M2; CD44 receptor; Classical phenotype M1; Insulin resistance

Indexed keywords

CD68 ANTIGEN; GLUCOSE; HERMES ANTIGEN; INSULIN; INTERLEUKIN 6; OSTEOPONTIN; ANTIDIABETIC AGENT;

ADIPOSE TISSUE; ADULT; ARTICLE; BLOOD LEVEL; CELL SURFACE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; POLARIZATION; PRIORITY JOURNAL; SUBCUTANEOUS FAT; COHORT ANALYSIS; CYTOLOGY; DIET; GENETIC ASSOCIATION; GENETICS; METABOLISM; MIDDLE AGED; PHYSIOLOGY;

ADIPOSE TISSUE; ANTIGENS, CD44; COHORT STUDIES; DIABETES MELLITUS, TYPE 2; DIET; FEMALE; GENE EXPRESSION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; HYPOGLYCEMIC AGENTS; INFLAMMATION; INSULIN; INSULIN RESISTANCE; MACROPHAGES; MALE; MIDDLE AGED; OSTEOPONTIN; OVERWEIGHT; SUBCUTANEOUS FAT;

EID: 84931577126     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-015-3603-y     Document Type: Article

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