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Volumn 44, Issue , 2014, Pages 71-82

Circadian rhythmicity, variability and correlation of interleukin-6 levels in plasma and cerebrospinal fluid of healthy men

Author keywords

Blood brain barrier (BBB); Cerebrospinal fluid (CSF); Circadian; Cytokines; Immune; Inflammation; Interleukin 6 (IL 6); Neuroimmunology; Sleep; Stress

Indexed keywords

INTERLEUKIN 6;

EID: 84899501675     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2014.02.020     Document Type: Article
Times cited : (50)

References (128)
  • 1
    • 0027421831 scopus 로고
    • Interleukin-6 in biology and medicine
    • Akira S., Taga T., Kishimoto T. Interleukin-6 in biology and medicine. Adv. Immunol. 1993, 54:1-78.
    • (1993) Adv. Immunol. , vol.54 , pp. 1-78
    • Akira, S.1    Taga, T.2    Kishimoto, T.3
  • 2
    • 21044444562 scopus 로고    scopus 로고
    • Major depression is associated with significant diurnal elevations in plasma interleukin-6 levels, a shift of its circadian rhythm, and loss of physiological complexity in its secretion: clinical implications
    • Alesci S., Martinez P.E., Kelkar S., Ilias I., Ronsaville D.S., Listwak S.J., Ayala A.R., Licinio J., Gold H.K., Kling M.A., Chrousos G.P., Gold P.W. Major depression is associated with significant diurnal elevations in plasma interleukin-6 levels, a shift of its circadian rhythm, and loss of physiological complexity in its secretion: clinical implications. J. Clin. Endocrinol. Metab. 2005, 90:2522-2530.
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 2522-2530
    • Alesci, S.1    Martinez, P.E.2    Kelkar, S.3    Ilias, I.4    Ronsaville, D.S.5    Listwak, S.J.6    Ayala, A.R.7    Licinio, J.8    Gold, H.K.9    Kling, M.A.10    Chrousos, G.P.11    Gold, P.W.12
  • 3
    • 0028049995 scopus 로고
    • Penetration of interleukin-6 across the murine blood-brain barrier
    • Banks W.A., Kastin A.J., Gutierrez E.G. Penetration of interleukin-6 across the murine blood-brain barrier. Neurosci. Lett. 1994, 179:53-56.
    • (1994) Neurosci. Lett. , vol.179 , pp. 53-56
    • Banks, W.A.1    Kastin, A.J.2    Gutierrez, E.G.3
  • 5
    • 84865988198 scopus 로고    scopus 로고
    • Circadian rhythms, symptoms, physical functioning, and body mass index in breast cancer survivors
    • Berger A.M., Hertzog M., Geary C.R., Fischer P., Farr L. Circadian rhythms, symptoms, physical functioning, and body mass index in breast cancer survivors. J. Cancer Surviv. 2012.
    • (2012) J. Cancer Surviv.
    • Berger, A.M.1    Hertzog, M.2    Geary, C.R.3    Fischer, P.4    Farr, L.5
  • 6
    • 78651330400 scopus 로고    scopus 로고
    • Central and peripheral cytokines mediate immune-brain connectivity
    • Besedovsky H.O., del Rey A. Central and peripheral cytokines mediate immune-brain connectivity. Neurochem. Res. 2011, 36:1-6.
    • (2011) Neurochem. Res. , vol.36 , pp. 1-6
    • Besedovsky, H.O.1    del Rey, A.2
  • 7
    • 0034255366 scopus 로고    scopus 로고
    • Interleukin-6 is an essential, corticotropin-releasing hormone-independent stimulator of the adrenal axis during immune system activation
    • Bethin K.E., Vogt S.K., Muglia L.J. Interleukin-6 is an essential, corticotropin-releasing hormone-independent stimulator of the adrenal axis during immune system activation. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:9317-9322.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 9317-9322
    • Bethin, K.E.1    Vogt, S.K.2    Muglia, L.J.3
  • 8
    • 33645739234 scopus 로고    scopus 로고
    • The neurobiology of the human febrile response
    • Biddle C. The neurobiology of the human febrile response. AANA J. 2006, 74:145-150.
    • (2006) AANA J. , vol.74 , pp. 145-150
    • Biddle, C.1
  • 9
    • 0033830170 scopus 로고    scopus 로고
    • Role of IL-6 in cytokine-induced sickness behavior: a study with IL-6 deficient mice
    • Bluthe R.M., Michaud B., Poli V., Dantzer R. Role of IL-6 in cytokine-induced sickness behavior: a study with IL-6 deficient mice. Physiol. Behav. 2000, 70:367-373.
    • (2000) Physiol. Behav. , vol.70 , pp. 367-373
    • Bluthe, R.M.1    Michaud, B.2    Poli, V.3    Dantzer, R.4
  • 10
    • 84887234585 scopus 로고    scopus 로고
    • Neuroprotein dynamics in the cerebrospinal fluid: intraindividual concomitant ventricular and lumbar measurements
    • Brandner S., Thaler C., Lewczuk P., Lelental N., Buchfelder M., Kleindienst A. Neuroprotein dynamics in the cerebrospinal fluid: intraindividual concomitant ventricular and lumbar measurements. Eur. Neurol. 2013, 70:189-194.
    • (2013) Eur. Neurol. , vol.70 , pp. 189-194
    • Brandner, S.1    Thaler, C.2    Lewczuk, P.3    Lelental, N.4    Buchfelder, M.5    Kleindienst, A.6
  • 11
    • 3042526109 scopus 로고    scopus 로고
    • Discrimination ratio analysis of inflammatory markers: implications for the study of inflammation in chronic disease
    • Browning L.M., Krebs J.D., Jebb S.A. Discrimination ratio analysis of inflammatory markers: implications for the study of inflammation in chronic disease. Metabolism 2004, 53:899-903.
    • (2004) Metabolism , vol.53 , pp. 899-903
    • Browning, L.M.1    Krebs, J.D.2    Jebb, S.A.3
  • 12
    • 2942622323 scopus 로고    scopus 로고
    • Sick and tired: does sleep have a vital role in the immune system?
    • Bryant P.A., Trinder J., Curtis N. Sick and tired: does sleep have a vital role in the immune system?. Nat. Rev. Immunol. 2004, 4:457-467.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 457-467
    • Bryant, P.A.1    Trinder, J.2    Curtis, N.3
  • 14
    • 3142710172 scopus 로고    scopus 로고
    • Interleukin-6 and tumor necrosis factor-alpha are not increased in patients with Type 2 diabetes: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness
    • Carey A.L., Bruce C.R., Sacchetti M., Anderson M.J., Olsen D.B., Saltin B., Hawley J.A., Febbraio M.A. Interleukin-6 and tumor necrosis factor-alpha are not increased in patients with Type 2 diabetes: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness. Diabetologia 2004, 47:1029-1037.
    • (2004) Diabetologia , vol.47 , pp. 1029-1037
    • Carey, A.L.1    Bruce, C.R.2    Sacchetti, M.3    Anderson, M.J.4    Olsen, D.B.5    Saltin, B.6    Hawley, J.A.7    Febbraio, M.A.8
  • 18
    • 0029037126 scopus 로고
    • The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation
    • Chrousos G.P. The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. N. Engl. J. Med. 1995, 332:1351-1362.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1351-1362
    • Chrousos, G.P.1
  • 19
    • 0035857757 scopus 로고    scopus 로고
    • Melatonin reduces interleukin secretion in amyloid-beta stressed mouse brain slices
    • Clapp-Lilly K.L., Smith M.A., Perry G., Duffy L.K. Melatonin reduces interleukin secretion in amyloid-beta stressed mouse brain slices. Chem. Biol. Interact. 2001, 134:101-107.
    • (2001) Chem. Biol. Interact. , vol.134 , pp. 101-107
    • Clapp-Lilly, K.L.1    Smith, M.A.2    Perry, G.3    Duffy, L.K.4
  • 21
    • 50849133535 scopus 로고    scopus 로고
    • Neuroimmunology of the circadian clock
    • Coogan A.N., Wyse C.A. Neuroimmunology of the circadian clock. Brain Res. 2008, 1232:104-112.
    • (2008) Brain Res. , vol.1232 , pp. 104-112
    • Coogan, A.N.1    Wyse, C.A.2
  • 22
    • 0030936387 scopus 로고    scopus 로고
    • Circadian relationships between interleukin (IL)-6 and hypothalamic-pituitary-adrenal axis hormones: failure of IL-6 to cause sustained hypercortisolism in patients with early untreated rheumatoid arthritis
    • Crofford L.J., Kalogeras K.T., Mastorakos G., Magiakou M.A., Wells J., Kanik K.S., Gold P.W., Chrousos G.P., Wilder R.L. Circadian relationships between interleukin (IL)-6 and hypothalamic-pituitary-adrenal axis hormones: failure of IL-6 to cause sustained hypercortisolism in patients with early untreated rheumatoid arthritis. J. Clin. Endocrinol. Metab. 1997, 82:1279-1283.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 1279-1283
    • Crofford, L.J.1    Kalogeras, K.T.2    Mastorakos, G.3    Magiakou, M.A.4    Wells, J.5    Kanik, K.S.6    Gold, P.W.7    Chrousos, G.P.8    Wilder, R.L.9
  • 24
    • 26244451354 scopus 로고    scopus 로고
    • Altered circadian rhythms in rheumatoid arthritis patients play a role in the disease's symptoms
    • Cutolo M., Villaggio B., Otsa K., Aakre O., Sulli A., Seriolo B. Altered circadian rhythms in rheumatoid arthritis patients play a role in the disease's symptoms. Autoimmun. Rev. 2005, 4:497-502.
    • (2005) Autoimmun. Rev. , vol.4 , pp. 497-502
    • Cutolo, M.1    Villaggio, B.2    Otsa, K.3    Aakre, O.4    Sulli, A.5    Seriolo, B.6
  • 25
    • 0035666553 scopus 로고    scopus 로고
    • Is obesity an inflammatory condition?
    • Das U.N. Is obesity an inflammatory condition?. Nutrition 2001, 17:953-966.
    • (2001) Nutrition , vol.17 , pp. 953-966
    • Das, U.N.1
  • 26
    • 0028819533 scopus 로고
    • Central endotoxin induces different patterns of interleukin (IL)-1 beta and IL-6 messenger ribonucleic acid expression and IL-6 secretion in the brain and periphery
    • De Simoni M.G., Del Bo R., De Luigi A., Simard S., Forloni G. Central endotoxin induces different patterns of interleukin (IL)-1 beta and IL-6 messenger ribonucleic acid expression and IL-6 secretion in the brain and periphery. Endocrinology 1995, 136:897-902.
    • (1995) Endocrinology , vol.136 , pp. 897-902
    • De Simoni, M.G.1    Del Bo, R.2    De Luigi, A.3    Simard, S.4    Forloni, G.5
  • 29
    • 0344972882 scopus 로고    scopus 로고
    • Short-term variability in the concentration of serum interleukin-6 and its soluble receptor in subjectively healthy persons
    • Dugue B., Leppanen E. Short-term variability in the concentration of serum interleukin-6 and its soluble receptor in subjectively healthy persons. Clin. Chem. Lab. Med. 1998, 36:323-325.
    • (1998) Clin. Chem. Lab. Med. , vol.36 , pp. 323-325
    • Dugue, B.1    Leppanen, E.2
  • 30
    • 36849037934 scopus 로고    scopus 로고
    • Neurohormonal-cytokine interactions: implications for inflammation, common human diseases and well-being
    • Elenkov I.J. Neurohormonal-cytokine interactions: implications for inflammation, common human diseases and well-being. Neurochem. Int. 2008, 52:40-51.
    • (2008) Neurochem. Int. , vol.52 , pp. 40-51
    • Elenkov, I.J.1
  • 33
    • 62449319038 scopus 로고    scopus 로고
    • Defining chronodisruption
    • Erren T.C., Reiter R.J. Defining chronodisruption. J. Pineal Res. 2009, 46:245-247.
    • (2009) J. Pineal Res. , vol.46 , pp. 245-247
    • Erren, T.C.1    Reiter, R.J.2
  • 37
    • 0033809810 scopus 로고    scopus 로고
    • Correlation between nuclear melatonin receptor expression and enhanced cytokine production in human lymphocytic and monocytic cell lines
    • Garcia-Maurino S., Pozo D., Calvo J.R., Guerrero J.M. Correlation between nuclear melatonin receptor expression and enhanced cytokine production in human lymphocytic and monocytic cell lines. J. Pineal Res. 2000, 29:129-137.
    • (2000) J. Pineal Res. , vol.29 , pp. 129-137
    • Garcia-Maurino, S.1    Pozo, D.2    Calvo, J.R.3    Guerrero, J.M.4
  • 39
    • 84899579763 scopus 로고    scopus 로고
    • Influence of hypothalamic IL-6/gp130 receptor signaling on the HPA axis response to chronic stress
    • Girotti M., Donegan J.J., Morilak D.A. Influence of hypothalamic IL-6/gp130 receptor signaling on the HPA axis response to chronic stress. Psychoneuroendocrinology 2012.
    • (2012) Psychoneuroendocrinology
    • Girotti, M.1    Donegan, J.J.2    Morilak, D.A.3
  • 40
    • 0031301027 scopus 로고    scopus 로고
    • Physiological and pathological roles of interleukin-6 in the central nervous system
    • Gruol D.L., Nelson T.E. Physiological and pathological roles of interleukin-6 in the central nervous system. Mol. Neurobiol. 1997, 15:307-339.
    • (1997) Mol. Neurobiol. , vol.15 , pp. 307-339
    • Gruol, D.L.1    Nelson, T.E.2
  • 43
    • 0036843216 scopus 로고    scopus 로고
    • Diurnal variations of interleukin-6 plasma levels are confounded by blood drawing procedures
    • Haack M., Kraus T., Schuld A., Dalal M., Koethe D., Pollmacher T. Diurnal variations of interleukin-6 plasma levels are confounded by blood drawing procedures. Psychoneuroendocrinology 2002, 27:921-931.
    • (2002) Psychoneuroendocrinology , vol.27 , pp. 921-931
    • Haack, M.1    Kraus, T.2    Schuld, A.3    Dalal, M.4    Koethe, D.5    Pollmacher, T.6
  • 44
    • 2442457425 scopus 로고    scopus 로고
    • Diurnal and sleep-wake dependent variations of soluble TNF- and IL-2 receptors in healthy volunteers
    • Haack M., Pollmacher T., Mullington J.M. Diurnal and sleep-wake dependent variations of soluble TNF- and IL-2 receptors in healthy volunteers. Brain. Behav. Immun. 2004, 18:361-367.
    • (2004) Brain. Behav. Immun. , vol.18 , pp. 361-367
    • Haack, M.1    Pollmacher, T.2    Mullington, J.M.3
  • 45
    • 0033937544 scopus 로고    scopus 로고
    • Effects of an intravenous catheter on the local production of cytokines and soluble cytokine receptors in healthy men
    • Haack M., Reichenberg A., Kraus T., Schuld A., Yirmiya R., Pollmacher T. Effects of an intravenous catheter on the local production of cytokines and soluble cytokine receptors in healthy men. Cytokine 2000, 12:694-698.
    • (2000) Cytokine , vol.12 , pp. 694-698
    • Haack, M.1    Reichenberg, A.2    Kraus, T.3    Schuld, A.4    Yirmiya, R.5    Pollmacher, T.6
  • 47
    • 84865634389 scopus 로고    scopus 로고
    • Beta adrenergic blockade decreases the immunomodulatory effects of social disruption stress
    • Hanke M.L., Powell N.D., Stiner L.M., Bailey M.T., Sheridan J.F. Beta adrenergic blockade decreases the immunomodulatory effects of social disruption stress. Brain. Behav. Immun. 2012, 26:1150-1159.
    • (2012) Brain. Behav. Immun. , vol.26 , pp. 1150-1159
    • Hanke, M.L.1    Powell, N.D.2    Stiner, L.M.3    Bailey, M.T.4    Sheridan, J.F.5
  • 48
    • 77955927147 scopus 로고    scopus 로고
    • Inflammation as a psychophysiological biomarker in chronic psychosocial stress
    • Hansel A., Hong S., Camara R.J., von Kanel R. Inflammation as a psychophysiological biomarker in chronic psychosocial stress. Neurosci. Biobehav. Rev. 2010, 35:115-121.
    • (2010) Neurosci. Biobehav. Rev. , vol.35 , pp. 115-121
    • Hansel, A.1    Hong, S.2    Camara, R.J.3    von Kanel, R.4
  • 50
    • 0025190892 scopus 로고
    • Interleukin-6 and the acute phase response
    • Heinrich P.C., Castell J.V., Andus T. Interleukin-6 and the acute phase response. Biochem. J. 1990, 265:621-636.
    • (1990) Biochem. J. , vol.265 , pp. 621-636
    • Heinrich, P.C.1    Castell, J.V.2    Andus, T.3
  • 51
    • 46649121834 scopus 로고    scopus 로고
    • Central nervous system administration of interleukin-6 produces splenic sympathoexcitation
    • Helwig B.G., Craig R.A., Fels R.J., Blecha F., Kenney M.J. Central nervous system administration of interleukin-6 produces splenic sympathoexcitation. Auton. Neurosci. 2008, 141:104-111.
    • (2008) Auton. Neurosci. , vol.141 , pp. 104-111
    • Helwig, B.G.1    Craig, R.A.2    Fels, R.J.3    Blecha, F.4    Kenney, M.J.5
  • 53
    • 34347261376 scopus 로고    scopus 로고
    • Central nervous system recognition of peripheral inflammation: a neural, hormonal collaboration
    • Hopkins S.J. Central nervous system recognition of peripheral inflammation: a neural, hormonal collaboration. Acta Biomed. 2007, 78(Suppl. 1):231-247.
    • (2007) Acta Biomed. , vol.78 , Issue.SUPPL. 1 , pp. 231-247
    • Hopkins, S.J.1
  • 54
    • 60549090569 scopus 로고    scopus 로고
    • How (and why) the immune system makes us sleep
    • Imeri L., Opp M.R. How (and why) the immune system makes us sleep. Nat. Rev. Neurosci. 2009, 10:199-210.
    • (2009) Nat. Rev. Neurosci. , vol.10 , pp. 199-210
    • Imeri, L.1    Opp, M.R.2
  • 55
    • 77955980762 scopus 로고    scopus 로고
    • Chronotherapy and the molecular clock: clinical implications in oncology
    • Innominato P.F., Levi F.A., Bjarnason G.A. Chronotherapy and the molecular clock: clinical implications in oncology. Adv. Drug. Deliv. Rev. 2010, 62:979-1001.
    • (2010) Adv. Drug. Deliv. Rev. , vol.62 , pp. 979-1001
    • Innominato, P.F.1    Levi, F.A.2    Bjarnason, G.A.3
  • 56
    • 0036430435 scopus 로고    scopus 로고
    • Effects of sleep and sleep loss on immunity and cytokines
    • Irwin M. Effects of sleep and sleep loss on immunity and cytokines. Brain Behav. Immun. 2002, 16:503-512.
    • (2002) Brain Behav. Immun. , vol.16 , pp. 503-512
    • Irwin, M.1
  • 57
    • 81455128683 scopus 로고    scopus 로고
    • The relationship between treatment time of gemcitabine and development of hematologic toxicity in cancer patients
    • Iwata K., Aizawa K., Sakai S., Jingami S., Fukunaga E., Yoshida M., Hamada A., Saito H. The relationship between treatment time of gemcitabine and development of hematologic toxicity in cancer patients. Biol. Pharm. Bull. 2011, 34:1765-1768.
    • (2011) Biol. Pharm. Bull. , vol.34 , pp. 1765-1768
    • Iwata, K.1    Aizawa, K.2    Sakai, S.3    Jingami, S.4    Fukunaga, E.5    Yoshida, M.6    Hamada, A.7    Saito, H.8
  • 58
    • 84870746772 scopus 로고    scopus 로고
    • The diurnal patterns of salivary interleukin-6 and C-reactive protein in healthy young adults
    • Izawa S., Miki K., Liu X., Ogawa N. The diurnal patterns of salivary interleukin-6 and C-reactive protein in healthy young adults. Brain Behav. Immun. 2013, 27:38-41.
    • (2013) Brain Behav. Immun. , vol.27 , pp. 38-41
    • Izawa, S.1    Miki, K.2    Liu, X.3    Ogawa, N.4
  • 59
    • 84870746772 scopus 로고    scopus 로고
    • The diurnal patterns of salivary interleukin-6 and C-reactive protein in healthy young adults
    • Izawa S., Miki K., Liu X.X., Ogawa N. The diurnal patterns of salivary interleukin-6 and C-reactive protein in healthy young adults. Brain Behav. Immun. 2013, 27:38-41.
    • (2013) Brain Behav. Immun. , vol.27 , pp. 38-41
    • Izawa, S.1    Miki, K.2    Liu, X.X.3    Ogawa, N.4
  • 60
    • 0031781290 scopus 로고    scopus 로고
    • Cytokine expression in the rat adrenal cortex
    • Judd A.M. Cytokine expression in the rat adrenal cortex. Horm. Metab. Res. 1998, 30:404-410.
    • (1998) Horm. Metab. Res. , vol.30 , pp. 404-410
    • Judd, A.M.1
  • 61
    • 0036113566 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6): a possible neuromodulator induced by neuronal activity
    • Juttler E., Tarabin V., Schwaninger M. Interleukin-6 (IL-6): a possible neuromodulator induced by neuronal activity. Neuroscientist 2002, 8:268-275.
    • (2002) Neuroscientist , vol.8 , pp. 268-275
    • Juttler, E.1    Tarabin, V.2    Schwaninger, M.3
  • 63
    • 0000935584 scopus 로고    scopus 로고
    • Molecular and cellular biology of interleukin-6 and its receptor
    • Keller E.T., Wanagat J., Ershler W.B. Molecular and cellular biology of interleukin-6 and its receptor. Front. Biosci. 1996, 1:d340-d357.
    • (1996) Front. Biosci. , vol.1
    • Keller, E.T.1    Wanagat, J.2    Ershler, W.B.3
  • 65
    • 84899520648 scopus 로고    scopus 로고
    • Interleukin-6 autocrine signaling mediates melatonin MT(1/2) receptor-induced STAT3 Tyr(705) phosphorylation
    • Lau W.W., Ng J.K., Lee M.M., Chan A.S., Wong Y.H. Interleukin-6 autocrine signaling mediates melatonin MT(1/2) receptor-induced STAT3 Tyr(705) phosphorylation. J. Pineal Res. 2011.
    • (2011) J. Pineal Res.
    • Lau, W.W.1    Ng, J.K.2    Lee, M.M.3    Chan, A.S.4    Wong, Y.H.5
  • 66
    • 0026856975 scopus 로고
    • Circadian rhythm of soluble interleukin-2 receptor in healthy individuals
    • Lemmer B., Schwulera U., Thrun A., Lissner R. Circadian rhythm of soluble interleukin-2 receptor in healthy individuals. Eur. Cytokine Netw. 1992, 3:335-336.
    • (1992) Eur. Cytokine Netw. , vol.3 , pp. 335-336
    • Lemmer, B.1    Schwulera, U.2    Thrun, A.3    Lissner, R.4
  • 69
    • 0031739212 scopus 로고    scopus 로고
    • Circadian secretions of IL-2, IL-12 IL-6 and IL-10 in relation to the light/dark rhythm of the pineal hormone melatonin in healthy humans
    • Lissoni P., Rovelli F., Brivio F., Brivio O., Fumagalli L. Circadian secretions of IL-2, IL-12 IL-6 and IL-10 in relation to the light/dark rhythm of the pineal hormone melatonin in healthy humans. Nat. Immun. 1998, 16:1-5.
    • (1998) Nat. Immun. , vol.16 , pp. 1-5
    • Lissoni, P.1    Rovelli, F.2    Brivio, F.3    Brivio, O.4    Fumagalli, L.5
  • 70
    • 10444245917 scopus 로고    scopus 로고
    • Human pineal physiology and functional significance of melatonin
    • Macchi M.M., Bruce J.N. Human pineal physiology and functional significance of melatonin. Front. Neuroendocrinol. 2004, 25:177-195.
    • (2004) Front. Neuroendocrinol. , vol.25 , pp. 177-195
    • Macchi, M.M.1    Bruce, J.N.2
  • 71
    • 22244441777 scopus 로고    scopus 로고
    • Physiological levels of pro- and anti-inflammatory mediators in cerebrospinal fluid and plasma: a normative study
    • Maier B., Laurer H.L., Rose S., Buurman W.A., Marzi I. Physiological levels of pro- and anti-inflammatory mediators in cerebrospinal fluid and plasma: a normative study. J. Neurotrauma 2005, 22:822-835.
    • (2005) J. Neurotrauma , vol.22 , pp. 822-835
    • Maier, B.1    Laurer, H.L.2    Rose, S.3    Buurman, W.A.4    Marzi, I.5
  • 72
    • 0028925088 scopus 로고
    • Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis
    • Manolagas S.C., Jilka R.L. Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis. N. Engl. J. Med. 1995, 332:305-311.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 305-311
    • Manolagas, S.C.1    Jilka, R.L.2
  • 73
    • 0036355972 scopus 로고    scopus 로고
    • Brain-immune interactions in sleep
    • Marshall L., Born J. Brain-immune interactions in sleep. Int. Rev. Neurobiol. 2002, 52:93-131.
    • (2002) Int. Rev. Neurobiol. , vol.52 , pp. 93-131
    • Marshall, L.1    Born, J.2
  • 74
    • 0032826994 scopus 로고    scopus 로고
    • Neural activities of IL-6-type cytokines often depend on soluble cytokine receptors
    • Marz P., Otten U., Rose-John S. Neural activities of IL-6-type cytokines often depend on soluble cytokine receptors. Eur. J. Neurosci. 1999, 11:2995-3004.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 2995-3004
    • Marz, P.1    Otten, U.2    Rose-John, S.3
  • 75
    • 0027131202 scopus 로고
    • Recombinant interleukin-6 activates the hypothalamic-pituitary-adrenal axis in humans
    • Mastorakos G., Chrousos G.P., Weber J.S. Recombinant interleukin-6 activates the hypothalamic-pituitary-adrenal axis in humans. J. Clin. Endocrinol. Metab. 1993, 77:1690-1694.
    • (1993) J. Clin. Endocrinol. Metab. , vol.77 , pp. 1690-1694
    • Mastorakos, G.1    Chrousos, G.P.2    Weber, J.S.3
  • 76
    • 84555205600 scopus 로고    scopus 로고
    • IL-6/IL-6 receptor system and its role in physiological and pathological conditions
    • Mihara M., Hashizume M., Yoshida H., Suzuki M., Shiina M. IL-6/IL-6 receptor system and its role in physiological and pathological conditions. Clin. Sci. (Lond.) 2012, 122:143-159.
    • (2012) Clin. Sci. (Lond.) , vol.122 , pp. 143-159
    • Mihara, M.1    Hashizume, M.2    Yoshida, H.3    Suzuki, M.4    Shiina, M.5
  • 79
    • 79959639352 scopus 로고    scopus 로고
    • Constant darkness induces IL-6-dependent depression-like behavior through the NF-kappaB signaling pathway
    • Monje F.J., Cabatic M., Divisch I., Kim E.J., Herkner K.R., Binder B.R., Pollak D.D. Constant darkness induces IL-6-dependent depression-like behavior through the NF-kappaB signaling pathway. J. Neurosci. 2011, 31:9075-9083.
    • (2011) J. Neurosci. , vol.31 , pp. 9075-9083
    • Monje, F.J.1    Cabatic, M.2    Divisch, I.3    Kim, E.J.4    Herkner, K.R.5    Binder, B.R.6    Pollak, D.D.7
  • 80
    • 0036196409 scopus 로고    scopus 로고
    • The human PER1 gene is inducible by interleukin-6
    • Motzkus D., Albrecht U., Maronde E. The human PER1 gene is inducible by interleukin-6. J. Mol. Neurosci. 2002, 18:105-109.
    • (2002) J. Mol. Neurosci. , vol.18 , pp. 105-109
    • Motzkus, D.1    Albrecht, U.2    Maronde, E.3
  • 81
    • 77952474442 scopus 로고    scopus 로고
    • Interactions of the circadian CLOCK system and the HPA axis
    • Nader N., Chrousos G.P., Kino T. Interactions of the circadian CLOCK system and the HPA axis. Trends Endocrinol. Metab. 2010, 21:277-286.
    • (2010) Trends Endocrinol. Metab. , vol.21 , pp. 277-286
    • Nader, N.1    Chrousos, G.P.2    Kino, T.3
  • 83
    • 77949875590 scopus 로고    scopus 로고
    • Interleukin-6 as a therapeutic target in candidate inflammatory diseases
    • Nishimoto N. Interleukin-6 as a therapeutic target in candidate inflammatory diseases. Clin. Pharmacol. Ther. 2010, 87:483-487.
    • (2010) Clin. Pharmacol. Ther. , vol.87 , pp. 483-487
    • Nishimoto, N.1
  • 84
    • 0028588573 scopus 로고
    • Neurotrophins: signals between the nervous and immune systems
    • Otten U., Scully J.L., Ehrhard P.B., Gadient R.A. Neurotrophins: signals between the nervous and immune systems. Prog. Brain Res. 1994, 103:293-305.
    • (1994) Prog. Brain Res. , vol.103 , pp. 293-305
    • Otten, U.1    Scully, J.L.2    Ehrhard, P.B.3    Gadient, R.A.4
  • 86
    • 0029931263 scopus 로고    scopus 로고
    • Acute glucocorticoid deficiency is associated with plasma elevations of interleukin-6: does the latter participate in the symptomatology of the steroid withdrawal syndrome and adrenal insufficiency?
    • Papanicolaou D.A., Tsigos C., Oldfield E.H., Chrousos G.P. Acute glucocorticoid deficiency is associated with plasma elevations of interleukin-6: does the latter participate in the symptomatology of the steroid withdrawal syndrome and adrenal insufficiency?. J. Clin. Endocrinol. Metab. 1996, 81:2303-2306.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 2303-2306
    • Papanicolaou, D.A.1    Tsigos, C.2    Oldfield, E.H.3    Chrousos, G.P.4
  • 88
    • 58349087639 scopus 로고    scopus 로고
    • Overnight variations in cortisol, interleukin 6, tumour necrosis factor alpha and other cytokines in people with rheumatoid arthritis
    • Perry M.G., Kirwan J.R., Jessop D.S., Hunt L.P. Overnight variations in cortisol, interleukin 6, tumour necrosis factor alpha and other cytokines in people with rheumatoid arthritis. Ann. Rheum. Dis. 2009, 68:63-68.
    • (2009) Ann. Rheum. Dis. , vol.68 , pp. 63-68
    • Perry, M.G.1    Kirwan, J.R.2    Jessop, D.S.3    Hunt, L.P.4
  • 89
    • 0033767521 scopus 로고    scopus 로고
    • Effects of sleep and sleep deprivation on interleukin-6, growth hormone, cortisol, and melatonin levels in humans
    • Redwine L., Hauger R.L., Gillin J.C., Irwin M. Effects of sleep and sleep deprivation on interleukin-6, growth hormone, cortisol, and melatonin levels in humans. J. Clin. Endocrinol. Metab. 2000, 85:3597-3603.
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 3597-3603
    • Redwine, L.1    Hauger, R.L.2    Gillin, J.C.3    Irwin, M.4
  • 90
    • 0035036277 scopus 로고    scopus 로고
    • Reporting cerebrospinal fluid data: knowledge base and interpretation software
    • Reiber H., Otto M., Trendelenburg C., Wormek A. Reporting cerebrospinal fluid data: knowledge base and interpretation software. Clin. Chem. Lab. Med. 2001, 39:324-332.
    • (2001) Clin. Chem. Lab. Med. , vol.39 , pp. 324-332
    • Reiber, H.1    Otto, M.2    Trendelenburg, C.3    Wormek, A.4
  • 91
    • 0029984183 scopus 로고    scopus 로고
    • Interleukin-1 beta differentially affects interleukin-6 and soluble interleukin-6 receptor in the blood and central nervous system of the monkey
    • Reyes T.M., Coe C.L. Interleukin-1 beta differentially affects interleukin-6 and soluble interleukin-6 receptor in the blood and central nervous system of the monkey. J. Neuroimmunol. 1996, 66:135-141.
    • (1996) J. Neuroimmunol. , vol.66 , pp. 135-141
    • Reyes, T.M.1    Coe, C.L.2
  • 92
    • 0031818522 scopus 로고    scopus 로고
    • Resistance of central nervous system interleukin-6 to glucocorticoid inhibition in monkeys
    • Reyes T.M., Coe C.L. Resistance of central nervous system interleukin-6 to glucocorticoid inhibition in monkeys. Am. J. Physiol. 1998, 275:R612-R618.
    • (1998) Am. J. Physiol. , vol.275
    • Reyes, T.M.1    Coe, C.L.2
  • 93
  • 94
    • 0028226196 scopus 로고
    • Soluble receptors for cytokines and growth factors: generation and biological function
    • Rose-John S., Heinrich P.C. Soluble receptors for cytokines and growth factors: generation and biological function. Biochem J. 1994, 300(Pt 2):281-290.
    • (1994) Biochem J. , vol.300 , Issue.PART 2 , pp. 281-290
    • Rose-John, S.1    Heinrich, P.C.2
  • 96
    • 0001501879 scopus 로고
    • Actigraphically based automatic bedtime sleep-wake scoring: validity and clinical applications
    • Sadeh A., Alster J., Urbach D., Lavie P.A. Actigraphically based automatic bedtime sleep-wake scoring: validity and clinical applications. Ambul. Monit. 1989, 2:209-216.
    • (1989) Ambul. Monit. , vol.2 , pp. 209-216
    • Sadeh, A.1    Alster, J.2    Urbach, D.3    Lavie, P.A.4
  • 97
    • 0025016942 scopus 로고
    • Interleukin-6 and ACTH act synergistically to stimulate the release of corticosterone from adrenal gland cells
    • Salas M.A., Evans S.W., Levell M.J., Whicher J.T. Interleukin-6 and ACTH act synergistically to stimulate the release of corticosterone from adrenal gland cells. Clin. Exp. Immunol. 1990, 79:470-473.
    • (1990) Clin. Exp. Immunol. , vol.79 , pp. 470-473
    • Salas, M.A.1    Evans, S.W.2    Levell, M.J.3    Whicher, J.T.4
  • 98
    • 0028865771 scopus 로고
    • Triggering of the human interleukin-6 gene by interferon-gamma and tumor necrosis factor-alpha in monocytic cells involves cooperation between interferon regulatory factor-1, NF kappa B, and Sp1 transcription factors
    • Sanceau J., Kaisho T., Hirano T., Wietzerbin J. Triggering of the human interleukin-6 gene by interferon-gamma and tumor necrosis factor-alpha in monocytic cells involves cooperation between interferon regulatory factor-1, NF kappa B, and Sp1 transcription factors. J. Biol. Chem. 1995, 270:27920-27931.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27920-27931
    • Sanceau, J.1    Kaisho, T.2    Hirano, T.3    Wietzerbin, J.4
  • 100
    • 0029118917 scopus 로고
    • Diurnal variations of plasma interleukin-6 in man: methodological implications of continuous use of indwelling cannulae
    • Seiler W., Muller H., Hiemke C. Diurnal variations of plasma interleukin-6 in man: methodological implications of continuous use of indwelling cannulae. Ann. N. Y. Acad. Sci. 1995, 762:468-470.
    • (1995) Ann. N. Y. Acad. Sci. , vol.762 , pp. 468-470
    • Seiler, W.1    Muller, H.2    Hiemke, C.3
  • 102
    • 0034529290 scopus 로고    scopus 로고
    • Changes in plasma concentrations of interleukin-6 and interleukin-1 receptor antagonists in response to adrenaline infusion in humans
    • Sondergaard S.R., Ostrowski K., Ullum H., Pedersen B.K. Changes in plasma concentrations of interleukin-6 and interleukin-1 receptor antagonists in response to adrenaline infusion in humans. Eur. J. Appl. Physiol. 2000, 83:95-98.
    • (2000) Eur. J. Appl. Physiol. , vol.83 , pp. 95-98
    • Sondergaard, S.R.1    Ostrowski, K.2    Ullum, H.3    Pedersen, B.K.4
  • 105
    • 77951831490 scopus 로고    scopus 로고
    • More night than day-circadian rhythms in polymyalgia rheumatica and ankylosing spondylitis
    • Spies C.M., Cutolo M., Straub R.H., Burmester G.R., Buttgereit F. More night than day-circadian rhythms in polymyalgia rheumatica and ankylosing spondylitis. J. Rheumatol. 2010, 37:894-899.
    • (2010) J. Rheumatol. , vol.37 , pp. 894-899
    • Spies, C.M.1    Cutolo, M.2    Straub, R.H.3    Burmester, G.R.4    Buttgereit, F.5
  • 110
    • 0141675985 scopus 로고    scopus 로고
    • Interleukin-6 levels in the central nervous system are negatively correlated with fat mass in overweight/obese subjects
    • Stenlof K., Wernstedt I., Fjallman T., Wallenius V., Wallenius K., Jansson J.O. Interleukin-6 levels in the central nervous system are negatively correlated with fat mass in overweight/obese subjects. J. Clin. Endocrinol. Metab. 2003, 88:4379-4383.
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 4379-4383
    • Stenlof, K.1    Wernstedt, I.2    Fjallman, T.3    Wallenius, V.4    Wallenius, K.5    Jansson, J.O.6
  • 111
    • 34548049265 scopus 로고    scopus 로고
    • The effects of acute psychological stress on circulating inflammatory factors in humans: a review and meta-analysis
    • Steptoe A., Hamer M., Chida Y. The effects of acute psychological stress on circulating inflammatory factors in humans: a review and meta-analysis. Brain Behav. Immun. 2007, 21:901-912.
    • (2007) Brain Behav. Immun. , vol.21 , pp. 901-912
    • Steptoe, A.1    Hamer, M.2    Chida, Y.3
  • 112
    • 0034975405 scopus 로고    scopus 로고
    • Neuroendocrine regulation of autoimmune/inflammatory disease
    • Sternberg E.M. Neuroendocrine regulation of autoimmune/inflammatory disease. J. Endocrinol. 2001, 169:429-435.
    • (2001) J. Endocrinol. , vol.169 , pp. 429-435
    • Sternberg, E.M.1
  • 114
    • 0034234414 scopus 로고    scopus 로고
    • Comparative evaluation of cytokine profiles and reactive gliosis supports a critical role for interleukin-6 in neuron-glia signaling during regeneration
    • Streit W.J., Hurley S.D., McGraw T.S., Semple-Rowland S.L. Comparative evaluation of cytokine profiles and reactive gliosis supports a critical role for interleukin-6 in neuron-glia signaling during regeneration. J. Neurosci. Res. 2000, 61:10-20.
    • (2000) J. Neurosci. Res. , vol.61 , pp. 10-20
    • Streit, W.J.1    Hurley, S.D.2    McGraw, T.S.3    Semple-Rowland, S.L.4
  • 116
    • 0034839726 scopus 로고    scopus 로고
    • Continuous interleukin-6 application in vivo via macroencapsulation of interleukin-6-expressing COS-7 cells induces massive gliosis
    • Tilgner J., Volk B., Kaltschmidt C. Continuous interleukin-6 application in vivo via macroencapsulation of interleukin-6-expressing COS-7 cells induces massive gliosis. Glia 2001, 35:234-245.
    • (2001) Glia , vol.35 , pp. 234-245
    • Tilgner, J.1    Volk, B.2    Kaltschmidt, C.3
  • 118
    • 0025165342 scopus 로고
    • The relation among stress, adrenalin, interleukin 6 and acute phase proteins in the rat
    • van Gool J., van Vugt H., Helle M., Aarden L.A. The relation among stress, adrenalin, interleukin 6 and acute phase proteins in the rat. Clin. Immunol. Immunopathol. 1990, 57:200-210.
    • (1990) Clin. Immunol. Immunopathol. , vol.57 , pp. 200-210
    • van Gool, J.1    van Vugt, H.2    Helle, M.3    Aarden, L.A.4
  • 119
    • 0033168292 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6) production by astrocytes: autocrine regulation by IL-6 and the soluble IL-6 receptor
    • Van Wagoner N.J., Oh J.W., Repovic P., Benveniste E.N. Interleukin-6 (IL-6) production by astrocytes: autocrine regulation by IL-6 and the soluble IL-6 receptor. J. Neurosci. 1999, 19:5236-5244.
    • (1999) J. Neurosci. , vol.19 , pp. 5236-5244
    • Van Wagoner, N.J.1    Oh, J.W.2    Repovic, P.3    Benveniste, E.N.4
  • 120
    • 0024497219 scopus 로고
    • Production of interleukin-6 by folliculo-stellate cells of the anterior pituitary gland in a histiotypic cell aggregate culture system
    • Vankelecom H., Carmeliet P., Van Damme J., Billiau A., Denef C. Production of interleukin-6 by folliculo-stellate cells of the anterior pituitary gland in a histiotypic cell aggregate culture system. Neuroendocrinology 1989, 49:102-106.
    • (1989) Neuroendocrinology , vol.49 , pp. 102-106
    • Vankelecom, H.1    Carmeliet, P.2    Van Damme, J.3    Billiau, A.4    Denef, C.5
  • 122
    • 0036014490 scopus 로고    scopus 로고
    • Sleep, the hypothalamic-pituitary-adrenal axis, and cytokines: multiple interactions and disturbances in sleep disorders
    • Vgontzas A.N., Chrousos G.P. Sleep, the hypothalamic-pituitary-adrenal axis, and cytokines: multiple interactions and disturbances in sleep disorders. Endocrinol. Metab. Clin. North Am. 2002, 31:15-36.
    • (2002) Endocrinol. Metab. Clin. North Am. , vol.31 , pp. 15-36
    • Vgontzas, A.N.1    Chrousos, G.P.2
  • 124
    • 0038030843 scopus 로고    scopus 로고
    • Impaired nighttime sleep in healthy old versus young adults is associated with elevated plasma interleukin-6 and cortisol levels: physiologic and therapeutic implications
    • Vgontzas A.N., Zoumakis M., Bixler E.O., Lin H.M., Prolo P., Vela-Bueno A., Kales A., Chrousos G.P. Impaired nighttime sleep in healthy old versus young adults is associated with elevated plasma interleukin-6 and cortisol levels: physiologic and therapeutic implications. J. Clin. Endocrinol. Metab. 2003, 88:2087-2095.
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 2087-2095
    • Vgontzas, A.N.1    Zoumakis, M.2    Bixler, E.O.3    Lin, H.M.4    Prolo, P.5    Vela-Bueno, A.6    Kales, A.7    Chrousos, G.P.8
  • 127
    • 0028933798 scopus 로고
    • Neuroendocrine-immune system interactions and autoimmunity
    • Wilder R.L. Neuroendocrine-immune system interactions and autoimmunity. Annu. Rev. Immunol. 1995, 13:307-338.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 307-338
    • Wilder, R.L.1
  • 128
    • 0027131192 scopus 로고
    • Exposure to physical and psychological stressors elevates plasma interleukin 6: relationship to the activation of hypothalamic-pituitary-adrenal axis
    • Zhou D., Kusnecov A.W., Shurin M.R., DePaoli M., Rabin B.S. Exposure to physical and psychological stressors elevates plasma interleukin 6: relationship to the activation of hypothalamic-pituitary-adrenal axis. Endocrinology 1993, 133:2523-2530.
    • (1993) Endocrinology , vol.133 , pp. 2523-2530
    • Zhou, D.1    Kusnecov, A.W.2    Shurin, M.R.3    DePaoli, M.4    Rabin, B.S.5


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