Damage to sperm DNA mediated by reactive oxygen species: Its impact on human reproduction and the health trajectory of offspring

Advances in Experimental Medicine and Biology

Volumn 868, Issue , 2015, Pages 23-47

  Gavriliouk, Dan ^a,b   Aitken, Robert John ^a,b,c  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b HUNTER MEDICAL RESEARCH INSTITUTE   (Australia)

^c UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

Apoptosis; Base excision repair; DNA damage; Histones; Oxidative stress; Protamines; Reactive oxygen species (ROS); Sperm mitochondria

Indexed keywords

CELL NUCLEUS DNA; PROTAMINE; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; CELL DIVISION; DNA DAMAGE; DNA END JOINING REPAIR; DNA REPAIR; DNA REPLICATION; EMBRYO DEVELOPMENT; EXCISION REPAIR; FERTILIZATION; GENE MUTATION; HOMOLOGOUS RECOMBINATION; HUMAN; INFERTILITY THERAPY; LEUKOCYTE; MISMATCH REPAIR; MITOCHONDRION; OBESITY; OXIDATIVE STRESS; PATERNAL AGE; PRIORITY JOURNAL; RADIATION EXPOSURE; REPRODUCTION; SMOKING; SPERM; SPERMATOZOON MOTILITY; SUBFERTILITY; ZYGOTE; MALE; METABOLISM; SPERMATOZOON; ULTRASTRUCTURE;

DNA DAMAGE; HUMANS; LEUKOCYTES; MALE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; REPRODUCTION; SPERMATOZOA;

EID: 84945356096     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-3-319-18881-2_2     Document Type: Chapter

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