메뉴 건너뛰기




Volumn 29, Issue 10, 2014, Pages 2136-2147

Potential importance of transition metals in the induction of DNA damage by sperm preparation media

Author keywords

Assisted reproduction technology; Colloidal silicon; Sperm DNA damage; Sperm preparation; Transition metals

Indexed keywords

ALUMINUM; CHROMOMYCIN; CUPRIC ION; IRON; REACTIVE OXYGEN METABOLITE; SILICON DIOXIDE; COLLOID; SILICON; TRANSITION ELEMENT;

EID: 84920686976     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/deu204     Document Type: Article
Times cited : (83)

References (50)
  • 1
    • 25144504039 scopus 로고    scopus 로고
    • Development of a novel electrophoretic system for the isolation of human spermatozoa
    • Ainsworth C, Nixon B, Aitken RJ. Development of a novel electrophoretic system for the isolation of human spermatozoa. Hum Reprod 2005;20:2261-2270.
    • (2005) Hum Reprod , vol.20 , pp. 2261-2270
    • Ainsworth, C.1    Nixon, B.2    Aitken, R.J.3
  • 2
    • 0024267840 scopus 로고
    • Significance of reactive oxygen species and antioxidants in defining the efficacy of sperm preparation techniques
    • Aitken RJ, Clarkson JS. Significance of reactive oxygen species and antioxidants in defining the efficacy of sperm preparation techniques. J Androl 1988;9:367-376.
    • (1988) J Androl , vol.9 , pp. 367-376
    • Aitken, R.J.1    Clarkson, J.S.2
  • 3
    • 58149289746 scopus 로고    scopus 로고
    • Biological and clinical significance of DNA damage in the male germ line
    • Aitken RJ, De Iuliis GN, McLachlan RI. Biological and clinical significance of DNA damage in the male germ line. Int J Androl 2009;32:46-56.
    • (2009) Int J Androl , vol.32 , pp. 46-56
    • Aitken, R.J.1    De Iuliis, G.N.2    McLachlan, R.I.3
  • 4
    • 77956912437 scopus 로고    scopus 로고
    • Analysis of the relationships between oxidative stress, DNA damage and sperm vitality in a patient population: Development of diagnostic criteria
    • Aitken RJ, De Iuliis GN, Finnie JM, Hedges A, McLachlan RI. Analysis of the relationships between oxidative stress, DNA damage and sperm vitality in a patient population: development of diagnostic criteria. Hum Reprod 2010;25:2415-2426.
    • (2010) Hum Reprod , vol.25 , pp. 2415-2426
    • Aitken, R.J.1    De Iuliis, G.N.2    Finnie, J.M.3    Hedges, A.4    McLachlan, R.I.5
  • 5
    • 79960500167 scopus 로고    scopus 로고
    • Electrophoretic sperm isolation: Optimization of electrophoresis conditions and impact on oxidative stress
    • Aitken RJ, Hanson AR, Kuczera L. Electrophoretic sperm isolation: optimization of electrophoresis conditions and impact on oxidative stress. Hum Reprod 2011;26:1955-1964.
    • (2011) Hum Reprod , vol.26 , pp. 1955-1964
    • Aitken, R.J.1    Hanson, A.R.2    Kuczera, L.3
  • 6
    • 84870715031 scopus 로고    scopus 로고
    • Reactive oxygen species and sperm function-in sickness and in health
    • Aitken RJ, Jones KT, Robertson SA. Reactive oxygen species and sperm function-in sickness and in health. J Androl 2012a; 33:1096-1106.
    • (2012) J Androl , vol.33 , pp. 1096-1106
    • Aitken, R.J.1    Jones, K.T.2    Robertson, S.A.3
  • 7
    • 84866529392 scopus 로고    scopus 로고
    • Electrophilic aldehydes generated by sperm metabolism activate mitochondrial reactive oxygen species generation and apoptosis by targeting succinate dehydrogenase
    • Aitken RJ, Whiting S, De Iuliis GN, McClymont S, Mitchell LA, Baker MA. Electrophilic aldehydes generated by sperm metabolism activate mitochondrial reactive oxygen species generation and apoptosis by targeting succinate dehydrogenase. J Biol Chem 2012b; 287:33048-33060.
    • (2012) J Biol Chem , vol.287 , pp. 33048-33060
    • Aitken, R.J.1    Whiting, S.2    De Iuliis, G.N.3    McClymont, S.4    Mitchell, L.A.5    Baker, M.A.6
  • 8
    • 84879729655 scopus 로고    scopus 로고
    • On methods for the detection of reactive oxygen species generation by human spermatozoa: Analysis of the cellular responses to catechol oestrogen, lipid aldehyde, menadione and arachidonic acid
    • Aitken RJ, Smith TB, Lord T, Kuczera L, Koppers AJ, Naumovski N, Connaughton H, Baker MA, De Iuliis GN. On methods for the detection of reactive oxygen species generation by human spermatozoa: analysis of the cellular responses to catechol oestrogen, lipid aldehyde, menadione and arachidonic acid. Andrology 2013;1:192-205.
    • (2013) Andrology , vol.1 , pp. 192-205
    • Aitken, R.J.1    Smith, T.B.2    Lord, T.3    Kuczera, L.4    Koppers, A.J.5    Naumovski, N.6    Connaughton, H.7    Baker, M.A.8    De Iuliis, G.N.9
  • 10
    • 0037305525 scopus 로고    scopus 로고
    • Aluminum and copper interact in the promotion of oxidative but not inflammatory events: Implications for Alzheimer's disease
    • Becaria A, Bondy SC, Campbell A. Aluminum and copper interact in the promotion of oxidative but not inflammatory events: implications for Alzheimer's disease. J Alzheimers Dis 2003;5:31-38.
    • (2003) J Alzheimers Dis , vol.5 , pp. 31-38
    • Becaria, A.1    Bondy, S.C.2    Campbell, A.3
  • 11
    • 0027430736 scopus 로고
    • Effect of deoxyribonucleic acid protamination on fluorochrome staining and in situ nick-translation of murine and human mature spermatozoa
    • Bianchi PG, Manicardi GC, Bizzaro D, Bianchi U, Sakkas D. Effect of deoxyribonucleic acid protamination on fluorochrome staining and in situ nick-translation of murine and human mature spermatozoa. Biol Reprod 1993;49:1083-1088.
    • (1993) Biol Reprod , vol.49 , pp. 1083-1088
    • Bianchi, P.G.1    Manicardi, G.C.2    Bizzaro, D.3    Bianchi, U.4    Sakkas, D.5
  • 12
    • 0002647611 scopus 로고
    • The cultureofmouse embryos in vitro
    • Daniel JC ed., San Francisco, CA: WH Freeman Press
    • Biggers JD, Whitten WK, Whittingham DG. The cultureofmouse embryos in vitro. In: Daniel JC (ed.). Methods of Mammalian Embryology. San Francisco, CA: WH Freeman Press, 1971, 86-116.
    • (1971) Methods of Mammalian Embryology , pp. 86-116
    • Biggers, J.D.1    Whitten, W.K.2    Whittingham, D.G.3
  • 13
    • 0036125774 scopus 로고    scopus 로고
    • Polymorphisms of glutathione S-transferase M1 and male infertility in Taiwanese patients with varicocele
    • Chen SS, Chang LS, Chen HW, Wei YH. Polymorphisms of glutathione S-transferase M1 and male infertility in Taiwanese patients with varicocele. Hum Reprod 2002;17:718-725.
    • (2002) Hum Reprod , vol.17 , pp. 718-725
    • Chen, S.S.1    Chang, L.S.2    Chen, H.W.3    Wei, Y.H.4
  • 15
    • 80051706721 scopus 로고    scopus 로고
    • Comparison of motility characteristics and normal sperm morphology of human semen samples separated by percoll density gradient centrifugation
    • Claassens OE, Kaskar K, Coetzee K, Lombard CJ, Franken DR, Kruger TF. Comparison of motility characteristics and normal sperm morphology of human semen samples separated by percoll density gradient centrifugation. Arch Androl 1996;36:127-132.
    • (1996) Arch Androl , vol.36 , pp. 127-132
    • Claassens, O.E.1    Kaskar, K.2    Coetzee, K.3    Lombard, C.J.4    Franken, D.R.5    Kruger, T.F.6
  • 16
    • 69849093579 scopus 로고    scopus 로고
    • DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2'-deoxyguanosine, a marker of oxidative stress
    • De Iuliis GN, Thomson LK, Mitchell LA, Finnie JM, Koppers AJ, Hedges A, Nixon B, Aitken RJ. DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2'-deoxyguanosine, a marker of oxidative stress. Biol Reprod 2009;81:517-524.
    • (2009) Biol Reprod , vol.81 , pp. 517-524
    • De Iuliis, G.N.1    Thomson, L.K.2    Mitchell, L.A.3    Finnie, J.M.4    Koppers, A.J.5    Hedges, A.6    Nixon, B.7    Aitken, R.J.8
  • 17
    • 0033802572 scopus 로고    scopus 로고
    • Differences in nuclear DNA fragmentation and mitochondrial integrity of semen and prepared human spermatozoa
    • Donnelly ET, O'Connell M, McClure N, Lewis SE. Differences in nuclear DNA fragmentation and mitochondrial integrity of semen and prepared human spermatozoa. Hum Reprod 2000;15:1552-1561.
    • (2000) Hum Reprod , vol.15 , pp. 1552-1561
    • Donnelly, E.T.1    O'Connell, M.2    McClure, N.3    Lewis, S.E.4
  • 18
    • 0034469287 scopus 로고    scopus 로고
    • Sperm chromatin structure assay is useful for fertility assessment
    • Evenson D, Jost L. Sperm chromatin structure assay is useful for fertility assessment. Methods Cell Sci 2000;22:169-189.
    • (2000) Methods Cell Sci , vol.22 , pp. 169-189
    • Evenson, D.1    Jost, L.2
  • 19
    • 0029917272 scopus 로고    scopus 로고
    • Smoking and low antioxidant levels increase oxidative damage to sperm DNA
    • Fraga CG, Motchnik PA, Wyrobek AJ, Rempel DM, Ames BN. Smoking and low antioxidant levels increase oxidative damage to sperm DNA. Mutat Res 1996;351:199-203.
    • (1996) Mutat Res , vol.351 , pp. 199-203
    • Fraga, C.G.1    Motchnik, P.A.2    Wyrobek, A.J.3    Rempel, D.M.4    Ames, B.N.5
  • 20
    • 84858035106 scopus 로고    scopus 로고
    • Sperm preparation: State-of-the-art-physiological aspects and application of advanced sperm preparation methods
    • Henkel R. Sperm preparation: state-of-the-art-physiological aspects and application of advanced sperm preparation methods. Asian J Androl 2012;14:260-269.
    • (2012) Asian J Androl , vol.14 , pp. 260-269
    • Henkel, R.1
  • 21
    • 7944222171 scopus 로고    scopus 로고
    • Zinc deficiency, DNA damage and cancer risk
    • Ho E. Zinc deficiency, DNA damage and cancer risk. J Nutr Biochem 2004;15:572-578.
    • (2004) J Nutr Biochem , vol.15 , pp. 572-578
    • Ho, E.1
  • 22
    • 84856227508 scopus 로고    scopus 로고
    • Geneticvariants in antioxidant genes are associated with sperm DNA damage and risk of male infertility in a Chinese population
    • Ji G, Gu A, Wang Y, Huang C, Hu F, Zhou Y, Song L, Wang X. Geneticvariants in antioxidant genes are associated with sperm DNA damage and risk of male infertility in a Chinese population. Free Radic Biol Med 2012;52:775-780.
    • (2012) Free Radic Biol Med , vol.52 , pp. 775-780
    • Ji, G.1    Gu, A.2    Wang, Y.3    Huang, C.4    Hu, F.5    Zhou, Y.6    Song, L.7    Wang, X.8
  • 23
    • 79954642381 scopus 로고    scopus 로고
    • Advances in metal-induced oxidative stress and human disease
    • Jomova K, Valko M. Advances in metal-induced oxidative stress and human disease. Toxicology 2011;283:65-87.
    • (2011) Toxicology , vol.283 , pp. 65-87
    • Jomova, K.1    Valko, M.2
  • 24
    • 0343907222 scopus 로고    scopus 로고
    • Increased oxidative deoxyribonucleic acid damage in the spermatozoa of infertile male patients
    • Kodama H, Yamaguchi R, Fukuda J, Kasai H, Tanaka T. Increased oxidative deoxyribonucleic acid damage in the spermatozoa of infertile male patients. Fertil Steril 1997;68:519-524.
    • (1997) Fertil Steril , vol.68 , pp. 519-524
    • Kodama, H.1    Yamaguchi, R.2    Fukuda, J.3    Kasai, H.4    Tanaka, T.5
  • 25
    • 49249112023 scopus 로고    scopus 로고
    • Significance of mitochondrial reactive oxygen species in the generation of oxidative stress in spermatozoa
    • Koppers AJ, De Iuliis GN, Finnie JM, McLaughlin EA, Aitken RJ. Significance of mitochondrial reactive oxygen species in the generation of oxidative stress in spermatozoa. J Clin Endocrinol Metab 2008;93:3199-3207.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 3199-3207
    • Koppers, A.J.1    De Iuliis, G.N.2    Finnie, J.M.3    McLaughlin, E.A.4    Aitken, R.J.5
  • 26
    • 79957778529 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase signalling pathway involvement in a truncated apoptotic cascade associated with motility loss and oxidative DNA damage in human spermatozoa
    • Koppers AJ, Mitchell LA, Wang P, Lin M, Aitken RJ. Phosphoinositide 3-kinase signalling pathway involvement in a truncated apoptotic cascade associated with motility loss and oxidative DNA damage in human spermatozoa. Biochem J 2011;436:687-698.
    • (2011) Biochem J , vol.436 , pp. 687-698
    • Koppers, A.J.1    Mitchell, L.A.2    Wang, P.3    Lin, M.4    Aitken, R.J.5
  • 27
    • 28844448158 scopus 로고    scopus 로고
    • A comet assay study reveals that aluminium induces DNA damage and inhibits the repair of radiation-induced lesions in human peripheral blood lymphocytes
    • Lankoff A, Banasik A, Duma A, Ochniak E, Lisowska H, Kuszewski T, Góźdź S, Wojcik A. A comet assay study reveals that aluminium induces DNA damage and inhibits the repair of radiation-induced lesions in human peripheral blood lymphocytes. Toxicol Lett 2006;161:27-36.
    • (2006) Toxicol Lett , vol.161 , pp. 27-36
    • Lankoff, A.1    Banasik, A.2    Duma, A.3    Ochniak, E.4    Lisowska, H.5    Kuszewski, T.6    Góźdź, S.7    Wojcik, A.8
  • 28
    • 0033535442 scopus 로고    scopus 로고
    • Oxidative DNA damage mediated by copper (II), iron (II) and nickel (II) fenton reactions: Evidence for site-specific mechanisms in the formation of double-strand breaks, 8-hydroxydeoxyguanosine and putative intrastrand cross-links
    • Lloyd DR, Phillips DH. Oxidative DNA damage mediated by copper (II), iron (II) and nickel (II) fenton reactions: evidence for site-specific mechanisms in the formation of double-strand breaks, 8-hydroxydeoxyguanosine and putative intrastrand cross-links. Mutat Res 1999;424:23-36.
    • (1999) Mutat Res , vol.424 , pp. 23-36
    • Lloyd, D.R.1    Phillips, D.H.2
  • 30
    • 0021348493 scopus 로고
    • Cell killing and DNA damage by hydrogen peroxide are mediated by intracellular iron
    • Mello Filho AC, Hoffmann ME, Meneghini R. Cell killing and DNA damage by hydrogen peroxide are mediated by intracellular iron. Biochem J 1984;218:273-275.
    • (1984) Biochem J , vol.218 , pp. 273-275
    • Mello Filho, A.C.1    Hoffmann, M.E.2    Meneghini, R.3
  • 31
    • 0018933454 scopus 로고
    • The damaging action of hydrogen peroxide on DNA of human fibroblasts is mediated by a non-dialyzable compound
    • Meneghini R, Hoffmann ME. The damaging action of hydrogen peroxide on DNA of human fibroblasts is mediated by a non-dialyzable compound. Biochim Biophys Acta 1980;608:167-173.
    • (1980) Biochim Biophys Acta , vol.608 , pp. 167-173
    • Meneghini, R.1    Hoffmann, M.E.2
  • 32
    • 78651297184 scopus 로고    scopus 로고
    • The TUNEL assay consistently underestimates DNA damage in human spermatozoa and is influenced by DNA compaction and cell vitality: Development of an improved methodology
    • Mitchell LA, De Iuliis GN, Aitken RJ. The TUNEL assay consistently underestimates DNA damage in human spermatozoa and is influenced by DNA compaction and cell vitality: development of an improved methodology. Int J Androl 2011;34:2-13.
    • (2011) Int J Androl , vol.34 , pp. 2-13
    • Mitchell, L.A.1    De Iuliis, G.N.2    Aitken, R.J.3
  • 33
    • 37249044260 scopus 로고    scopus 로고
    • Effects of mixing metal ions on oxidative DNA damage mediated by a Fenton-type reduction
    • Moriwaki H, Osborne MR, Phillips DH. Effects of mixing metal ions on oxidative DNA damage mediated by a Fenton-type reduction. Toxicol In Vitro 2008;22:36-44.
    • (2008) Toxicol in Vitro , vol.22 , pp. 36-44
    • Moriwaki, H.1    Osborne, M.R.2    Phillips, D.H.3
  • 35
    • 0022544232 scopus 로고
    • Increase in progressive motility and improved morphology of human spermatozoa following their migration through Percoll gradients
    • Pousette A, Akerlöf E, Rosenborg L, Fredricsson B. Increase in progressive motility and improved morphology of human spermatozoa following their migration through Percoll gradients. Int J Androl 1986;9:1-13.
    • (1986) Int J Androl , vol.9 , pp. 1-13
    • Pousette, A.1    Akerlöf, E.2    Rosenborg, L.3    Fredricsson, B.4
  • 36
    • 84883236408 scopus 로고    scopus 로고
    • Quantification of metal ion induced DNA damage with single cell array based assay
    • Qiao Y, Ma L. Quantification of metal ion induced DNA damage with single cell array based assay. Analyst 2013;138:5713-5718.
    • (2013) Analyst , vol.138 , pp. 5713-5718
    • Qiao, Y.1    Ma, L.2
  • 37
    • 43949130136 scopus 로고    scopus 로고
    • The assessment of oxidative stress in infertile patients with varicocele
    • Sakamoto Y, Ishikawa T, Kondo Y, Yamaguchi K, Fujisawa M. The assessment of oxidative stress in infertile patients with varicocele. BJU Int 2008;101:1547-1552.
    • (2008) BJU Int , vol.101 , pp. 1547-1552
    • Sakamoto, Y.1    Ishikawa, T.2    Kondo, Y.3    Yamaguchi, K.4    Fujisawa, M.5
  • 38
    • 0034014061 scopus 로고    scopus 로고
    • The use of two density gradient centrifugation techniques and the swim-up method to separate spermatozoa with chromatin and nuclear DNA anomalies
    • Sakkas D, Manicardi GC, Tomlinson M, Mandrioli M, Bizzaro D, Bianchi PG, Bianchi U. The use of two density gradient centrifugation techniques and the swim-up method to separate spermatozoa with chromatin and nuclear DNA anomalies. Hum Reprod 2000;15:1112-1116.
    • (2000) Hum Reprod , vol.15 , pp. 1112-1116
    • Sakkas, D.1    Manicardi, G.C.2    Tomlinson, M.3    Mandrioli, M.4    Bizzaro, D.5    Bianchi, P.G.6    Bianchi, U.7
  • 39
    • 0032702003 scopus 로고    scopus 로고
    • Evaluation of oxidative DNA damage in human sperm and its association with male infertility
    • Shen HM, Chia SE, Ong CN. Evaluation of oxidative DNA damage in human sperm and its association with male infertility. J Androl 1999;20:718-723.
    • (1999) J Androl , vol.20 , pp. 718-723
    • Shen, H.M.1    Chia, S.E.2    Ong, C.N.3
  • 41
    • 84877899886 scopus 로고    scopus 로고
    • The presence of a truncated base excision repair pathway in human spermatozoa, mediated by OGG1
    • Smith TB, Dun MD, Smith ND, Curry BJ, Connaughton HS, Aitken RJ. The presence of a truncated base excision repair pathway in human spermatozoa, mediated by OGG1. J Cell Sci. 2013;126:1488-1497.
    • (2013) J Cell Sci. , vol.126 , pp. 1488-1497
    • Smith, T.B.1    Dun, M.D.2    Smith, N.D.3    Curry, B.J.4    Connaughton, H.S.5    Aitken, R.J.6
  • 42
    • 51449118901 scopus 로고    scopus 로고
    • Semen processing by density gradient centrifugation does not improve sperm apoptotic deoxyribonucleic acid fragmentation rates
    • Stevanato J, Bertolla RP, Barradas V, Spaine DM, Cedenho AP, Ortiz V. Semen processing by density gradient centrifugation does not improve sperm apoptotic deoxyribonucleic acid fragmentation rates. Fertil Steril 2008;90:889-890.
    • (2008) Fertil Steril , vol.90 , pp. 889-890
    • Stevanato, J.1    Bertolla, R.P.2    Barradas, V.3    Spaine, D.M.4    Cedenho, A.P.5    Ortiz, V.6
  • 43
    • 84863025184 scopus 로고    scopus 로고
    • Genetic polymorphisms of glutathione S-transferase M1, T1, and P1, and the assessment of oxidative damage in infertile men with varicoceles from northwestern China
    • Tang K, Xue W, Xing Y, Xu S, Wu Q, Liu R, Wang X, Xing J. Genetic polymorphisms of glutathione S-transferase M1, T1, and P1, and the assessment of oxidative damage in infertile men with varicoceles from northwestern China. J Androl 2012;33:257-263.
    • (2012) J Androl , vol.33 , pp. 257-263
    • Tang, K.1    Xue, W.2    Xing, Y.3    Xu, S.4    Wu, Q.5    Liu, R.6    Wang, X.7    Xing, J.8
  • 44
    • 68949206432 scopus 로고    scopus 로고
    • Cryopreservation-induced human sperm DNA damage is predominantly mediated by oxidative stress rather than apoptosis
    • Thomson LK, Fleming SD, Aitken RJ, De Iuliis GN, Zieschang JA, Clark AM. Cryopreservation-induced human sperm DNA damage is predominantly mediated by oxidative stress rather than apoptosis. Hum Reprod 2009;24:2061-2070.
    • (2009) Hum Reprod , vol.24 , pp. 2061-2070
    • Thomson, L.K.1    Fleming, S.D.2    Aitken, R.J.3    De Iuliis, G.N.4    Zieschang, J.A.5    Clark, A.M.6
  • 45
  • 46
    • 0037427857 scopus 로고    scopus 로고
    • The associations among semen quality, oxidative DNA damage in human spermatozoa and concentrations of cadmium, lead and selenium in seminal plasma
    • Xu DX, Shen HM, Zhu QX, Chua L, Wang QN, Chia SE, Ong CN. The associations among semen quality, oxidative DNA damage in human spermatozoa and concentrations of cadmium, lead and selenium in seminal plasma. Mutat Res 2003;534:155-163.
    • (2003) Mutat Res , vol.534 , pp. 155-163
    • Xu, D.X.1    Shen, H.M.2    Zhu, Q.X.3    Chua, L.4    Wang, Q.N.5    Chia, S.E.6    Ong, C.N.7
  • 48
    • 0029022319 scopus 로고
    • Evaluation of the role of reactive oxygen species in male infertility
    • Zalata A, Hafez T, Comhaire F. Evaluation of the role of reactive oxygen species in male infertility. Hum Reprod 1995;10:1444-1451.
    • (1995) Hum Reprod , vol.10 , pp. 1444-1451
    • Zalata, A.1    Hafez, T.2    Comhaire, F.3
  • 49
    • 0033199503 scopus 로고    scopus 로고
    • Potential adverse effect of semen processing on human sperm deoxyribonucleic acid integrity
    • Zini A, Mak V, Phang D, Jarvi K. Potential adverse effect of semen processing on human sperm deoxyribonucleic acid integrity. Fertil Steril 1999;72:496-499.
    • (1999) Fertil Steril , vol.72 , pp. 496-499
    • Zini, A.1    Mak, V.2    Phang, D.3    Jarvi, K.4
  • 50
    • 0033668331 scopus 로고    scopus 로고
    • Influence ofsemen processing technique on human sperm DNA integrity
    • Zini A, Finelli A, Phang D, Jarvi K. Influence ofsemen processing technique on human sperm DNA integrity. Urology 2000;56:1081-1084.
    • (2000) Urology , vol.56 , pp. 1081-1084
    • Zini, A.1    Finelli, A.2    Phang, D.3    Jarvi, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.