-
1
-
-
84895734902
-
Functionally enigmatic genes: A case study of the brain ignorome
-
Pandey, A.K., Lu, L., Wang, X., Homayouni, R. and Williams, R.W. (2014) Functionally enigmatic genes: A case study of the brain ignorome. PLoS One, 9, e88889.
-
(2014)
PLoS One
, vol.9
, pp. e88889
-
-
Pandey, A.K.1
Lu, L.2
Wang, X.3
Homayouni, R.4
Williams, R.W.5
-
2
-
-
13444266370
-
Online mendelian inheritance in man (OMIM), a knowledgebase of human genes and genetic disorders
-
Hamosh, A., Scott, A.F., Amberger, J.S., Bocchini, C.A. and McKusick, V.A. (2005) Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res., 33, D514-D517.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. D514-D517
-
-
Hamosh, A.1
Scott, A.F.2
Amberger, J.S.3
Bocchini, C.A.4
McKusick, V.A.5
-
3
-
-
58149200928
-
Comparative toxicogenomics database: A knowledgebase and discovery tool for chemical-gene-disease networks
-
Davis, A.P., Murphy, C.G., Saraceni-Richards, C.A., Rosenstein, M.C., Wiegers, T.C. and Mattingly, C.J. (2009) Comparative Toxicogenomics Database: A knowledgebase and discovery tool for chemical-gene-disease networks. Nucleic Acids Res., 37, D786-D792.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. D786-D792
-
-
Davis, A.P.1
Murphy, C.G.2
Saraceni-Richards, C.A.3
Rosenstein, M.C.4
Wiegers, T.C.5
Mattingly, C.J.6
-
4
-
-
78149236787
-
DisGeNET: A cytoscape plugin to visualize, integrate, search and analyze gene-disease networks
-
Bauer-Mehren, A., Rautschka, M., Sanz, F. and Furlong, L.I. (2010) DisGeNET: A Cytoscape plugin to visualize, integrate, search and analyze gene-disease networks. Bioinformatics, 26, 2924-2926.
-
(2010)
Bioinformatics
, vol.26
, pp. 2924-2926
-
-
Bauer-Mehren, A.1
Rautschka, M.2
Sanz, F.3
Furlong, L.I.4
-
5
-
-
79958795334
-
Gene-disease network analysis reveals functional modules in mendelian, complex and environmental diseases
-
Bauer-Mehren, A., Bundschus, M., Rautschka, M., Mayer, M., Sanz, F. and Furlong, L. (2011) Gene-Disease Network Analysis Reveals Functional Modules in Mendelian, Complex and Environmental Diseases. PLoS One, 6, e20284.
-
(2011)
PLoS One
, vol.6
, pp. e20284
-
-
Bauer-Mehren, A.1
Bundschus, M.2
Rautschka, M.3
Mayer, M.4
Sanz, F.5
Furlong, L.6
-
6
-
-
84865822182
-
Systematic localization of common disease-associated variation in regulatory DNA
-
Maurano, M.T., Humbert, R., Rynes, E., Thurman, R.E., Haugen, E., Wang, H., Reynolds, A.P., Sandstrom, R., Qu, H., Brody, J. et al. (2012) Systematic Localization of Common Disease-Associated Variation in Regulatory DNA. Science, 337, 1190-1195.
-
(2012)
Science
, vol.337
, pp. 1190-1195
-
-
Maurano, M.T.1
Humbert, R.2
Rynes, E.3
Thurman, R.E.4
Haugen, E.5
Wang, H.6
Reynolds, A.P.7
Sandstrom, R.8
Qu, H.9
Brody, J.10
-
7
-
-
84864627693
-
Personal and population genomics of human regulatory variation
-
Vernot, B., Stergachis, A.B., Maurano, M.T., Vierstra, J., Neph, S., Thurman, R.E., Stamatoyannopoulos, J.A. and Akey, J.M. (2012) Personal and population genomics of human regulatory variation. Genome Res., 22, 1689-1697.
-
(2012)
Genome Res.
, vol.22
, pp. 1689-1697
-
-
Vernot, B.1
Stergachis, A.B.2
Maurano, M.T.3
Vierstra, J.4
Neph, S.5
Thurman, R.E.6
Stamatoyannopoulos, J.A.7
Akey, J.M.8
-
8
-
-
84923326765
-
Genetic and epigenetic fine mapping of causal autoimmune disease variants
-
Farh, K.K.-H., Marson, A., Zhu, J., Kleinewietfeld, M., Housley, W.J., Beik, S., Shoresh, N., Whitton, H., Ryan, R.J.H., Shishkin, A.A. et al. (2014) Genetic and epigenetic fine mapping of causal autoimmune disease variants. Nature, 518, 337-343.
-
(2014)
Nature
, vol.518
, pp. 337-343
-
-
Farh, K.K.-H.1
Marson, A.2
Zhu, J.3
Kleinewietfeld, M.4
Housley, W.J.5
Beik, S.6
Shoresh, N.7
Whitton, H.8
Ryan, R.J.H.9
Shishkin, A.A.10
-
9
-
-
84876216563
-
Master transcription factors and mediator establish super-enhancers at key cell identity genes
-
Whyte, W.A., Orlando, D.A., Hnisz, D., Abraham, B.J., Lin, C.Y., Kagey, M.H., Rahl, P.B., Lee, T.I. and Young, R.A. (2013) Master transcription factors and mediator establish super-enhancers at key cell identity genes. Cell, 153, 307-319.
-
(2013)
Cell
, vol.153
, pp. 307-319
-
-
Whyte, W.A.1
Orlando, D.A.2
Hnisz, D.3
Abraham, B.J.4
Lin, C.Y.5
Kagey, M.H.6
Rahl, P.B.7
Lee, T.I.8
Young, R.A.9
-
10
-
-
84887072795
-
Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants
-
Parker, S.C.J., Stitzel, M.L., Taylor, D.L., Orozco, J.M., Erdos, M.R., Akiyama, J.A., van Bueren, K.L., Chines, P.S., Narisu, N., Black, B.L. et al. (2013) Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants. Proc. Natl. Acad. Sci. U.S.A., 110, 17921-17926.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 17921-17926
-
-
Parker, S.C.J.1
Stitzel, M.L.2
Taylor, D.L.3
Orozco, J.M.4
Erdos, M.R.5
Akiyama, J.A.6
Van Bueren, K.L.7
Chines, P.S.8
Narisu, N.9
Black, B.L.10
-
11
-
-
84888015137
-
Super-enhancers in the control of cell identity and disease
-
Hnisz, D., Abraham, B.J., Lee, T.I., Lau, A., Saint-André, V., Sigova, A.A., Hoke, H.A. and Young, R.A. (2013) Super-enhancers in the control of cell identity and disease. Cell, 155, 934-947.
-
(2013)
Cell
, vol.155
, pp. 934-947
-
-
Hnisz, D.1
Abraham, B.J.2
Lee, T.I.3
Lau, A.4
Saint-André, V.5
Sigova, A.A.6
Hoke, H.A.7
Young, R.A.8
-
12
-
-
84902302671
-
Transcription factor cooperativity in early adipogenic hotspots and super-enhancers
-
Siersbæk, R., Rabiee, A., Nielsen, R., Sidoli, S., Traynor, S., Loft, A., Poulsen, L.L.C., Rogowska-Wrzesinska, A., Jensen, O.N. and Mandrup, S. (2014) Transcription Factor Cooperativity in Early Adipogenic Hotspots and Super-Enhancers. Cell Rep., 7, 1443-1455.
-
(2014)
Cell Rep.
, vol.7
, pp. 1443-1455
-
-
Siersbæk, R.1
Rabiee, A.2
Nielsen, R.3
Sidoli, S.4
Traynor, S.5
Loft, A.6
Poulsen, L.L.C.7
Rogowska-Wrzesinska, A.8
Jensen, O.N.9
Mandrup, S.10
-
13
-
-
84895806401
-
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
-
Pasquali, L., Gaulton, K.J., Rodríguez-Seguí, S.A., Mularoni, L., Miguel-Escalada, I., Akerman, I., Tena, J.J., Morán, I., Gómez-Marín, C., van de Bunt, M. et al. (2014) Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants. Nat. Genet., 46, 136-143.
-
(2014)
Nat. Genet.
, vol.46
, pp. 136-143
-
-
Pasquali, L.1
Gaulton, K.J.2
Rodríguez-Seguí, S.A.3
Mularoni, L.4
Miguel-Escalada, I.5
Akerman, I.6
Tena, J.J.7
Morán, I.8
Gómez-Marín, C.9
Van De-Bunt, M.10
-
14
-
-
84894284268
-
Integrated analysis of transcript-level regulation of metabolism reveals disease-relevant nodes of the human metabolic network
-
Galhardo, M., Sinkkonen, L., Berninger, P., Lin, J., Sauter, T. and Heinäniemi, M. (2014) Integrated analysis of transcript-level regulation of metabolism reveals disease-relevant nodes of the human metabolic network. Nucleic Acids Res., 42, 1474-1496.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 1474-1496
-
-
Galhardo, M.1
Sinkkonen, L.2
Berninger, P.3
Lin, J.4
Sauter, T.5
Heinäniemi, M.6
-
15
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian, A., Tamayo, P., Mootha, V.K., Mukherjee, S., Ebert, B.L., Gillette, M.A., Paulovich, A., Pomeroy, S.L., Golub, T.R., Lander, E.S. et al. (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. U.S.A., 102, 15545-15550.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
Paulovich, A.7
Pomeroy, S.L.8
Golub, T.R.9
Lander, E.S.10
-
16
-
-
0347755531
-
The UCSC table browser data retrieval tool
-
Karolchik, D., Hinrichs, A.S., Furey, T.S., Roskin, K.M., Sugnet, C.W., Haussler, D. and Kent, W.J. (2004) The UCSC Table Browser data retrieval tool. Nucleic Acids Res., 32, D493-D496.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. D493-D496
-
-
Karolchik, D.1
Hinrichs, A.S.2
Furey, T.S.3
Roskin, K.M.4
Sugnet, C.W.5
Haussler, D.6
Kent, W.J.7
-
17
-
-
77952214662
-
GREAT improves functional interpretation of cis-regulatory regions
-
McLean, C.Y., Bristor, D., Hiller, M., Clarke, S.L., Schaar, B.T., Lowe, C.B., Wenger, A.M. and Bejerano, G. (2010) GREAT improves functional interpretation of cis-regulatory regions. Nat. Biotechnol., 28, 495-501.
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 495-501
-
-
McLean, C.Y.1
Bristor, D.2
Hiller, M.3
Clarke, S.L.4
Schaar, B.T.5
Lowe, C.B.6
Wenger, A.M.7
Bejerano, G.8
-
18
-
-
77955895425
-
BigWig and bigbed: Enabling browsing of large distributed datasets
-
Kent, W.J., Zweig, A.S., Barber, G., Hinrichs, A.S. and Karolchik, D. (2010) BigWig and BigBed: enabling browsing of large distributed datasets. Bioinformatics, 26, 2204-2207.
-
(2010)
Bioinformatics
, vol.26
, pp. 2204-2207
-
-
Kent, W.J.1
Zweig, A.S.2
Barber, G.3
Hinrichs, A.S.4
Karolchik, D.5
-
19
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
Dunham, I., Kundaje, A., Aldred, S.F., Collins, P.J., Davis, C.A., Doyle, F., Epstein, C.B., Frietze, S., Harrow, J., Kaul, R. et al. (2012) An integrated encyclopedia of DNA elements in the human genome. Nature, 489, 57-74.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Dunham, I.1
Kundaje, A.2
Aldred, S.F.3
Collins, P.J.4
Davis, C.A.5
Doyle, F.6
Epstein, C.B.7
Frietze, S.8
Harrow, J.9
Kaul, R.10
-
20
-
-
84884950833
-
BLUEPRINT: Mapping human blood cell epigenomes
-
Martens, J.H.A. and Stunnenberg, H.G. (2013) BLUEPRINT: mapping human blood cell epigenomes. Haematologica, 98, 1487-1489.
-
(2013)
Haematologica
, vol.98
, pp. 1487-1489
-
-
Martens, J.H.A.1
Stunnenberg, H.G.2
-
21
-
-
84923362619
-
Integrative analysis of 111 reference human epigenomes
-
Consortium, R.E., Kundaje, A., Meuleman, W., Ernst, J., Bilenky, M., Yen, A., Heravi-Moussavi, A., Kheradpour, P., Zhang, Z., Wang, J. et al. (2015) Integrative analysis of 111 reference human epigenomes. Nature, 518, 317-330.
-
(2015)
Nature
, vol.518
, pp. 317-330
-
-
Consortium, R.E.1
Kundaje, A.2
Meuleman, W.3
Ernst, J.4
Bilenky, M.5
Yen, A.6
Heravi-Moussavi, A.7
Kheradpour, P.8
Zhang, Z.9
Wang, J.10
-
22
-
-
77951770756
-
BEDTools: A flexible suite of utilities for comparing genomic features
-
Quinlan, A.R. and Hall, I.M. (2010) BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics, 26, 841-842.
-
(2010)
Bioinformatics
, vol.26
, pp. 841-842
-
-
Quinlan, A.R.1
Hall, I.M.2
-
23
-
-
84880839435
-
Gene-pair expression signatures reveal lineage control
-
Heinäniemi, M., Nykter, M., Kramer, R., Wienecke-Baldacchino, A., Sinkkonen, L., Zhou, J.X., Kreisberg, R., Kauffman, S. a, Huang, S. and Shmulevich, I. (2013) Gene-pair expression signatures reveal lineage control. Nat. Methods, 10, 577-583.
-
(2013)
Nat. Methods
, vol.10
, pp. 577-583
-
-
Heinäniemi, M.1
Nykter, M.2
Kramer, R.3
Wienecke-Baldacchino, A.4
Sinkkonen, L.5
Zhou, J.X.6
Kreisberg, R.7
Kauffman, S.A.8
Huang, S.9
Shmulevich, I.10
-
25
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
Heinz, S., Benner, C., Spann, N., Bertolino, E., Lin, Y.C., Laslo, P., Cheng, J.X., Murre, C., Singh, H. and Glass, C.K. (2010) Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities. Mol. Cell, 38, 576-589.
-
(2010)
Mol. Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
Benner, C.2
Spann, N.3
Bertolino, E.4
Lin, Y.C.5
Laslo, P.6
Cheng, J.X.7
Murre, C.8
Singh, H.9
Glass, C.K.10
-
26
-
-
68449101067
-
Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt
-
Durinck, S., Spellman, P.T., Birney, E. and Huber, W. (2009) Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt. Nat. Protoc., 4, 1184-1191.
-
(2009)
Nat. Protoc.
, vol.4
, pp. 1184-1191
-
-
Durinck, S.1
Spellman, P.T.2
Birney, E.3
Huber, W.4
-
27
-
-
0033982936
-
KEGG: Kyoto encyclopaedia of genes and genomes
-
Kanehisa, M. and Goto, S. (2000) KEGG: Kyoto Encyclopaedia of Genes and Genomes. Nucl. Acids Res., 28, 27-30.
-
(2000)
Nucl. Acids Res.
, vol.28
, pp. 27-30
-
-
Kanehisa, M.1
Goto, S.2
-
28
-
-
84941026118
-
The comparative toxicogenomics Database's 10th year anniversary: Update 2015
-
Davis, A.P., Grondin, C.J., Lennon-Hopkins, K., Saraceni-Richards, C., Sciaky, D., King, B.L., Wiegers, T.C. and Mattingly, C.J. (2015) The Comparative Toxicogenomics Database's 10th year anniversary: update 2015. Nucleic Acids Res., 43, D914-D920.
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. D914-D920
-
-
Davis, A.P.1
Grondin, C.J.2
Lennon-Hopkins, K.3
Saraceni-Richards, C.4
Sciaky, D.5
King, B.L.6
Wiegers, T.C.7
Mattingly, C.J.8
-
29
-
-
58149193222
-
Human protein reference database-2009 update
-
Keshava Prasad, T.S., Goel, R., Kandasamy, K., Keerthikumar, S., Kumar, S., Mathivanan, S., Telikicherla, D., Raju, R., Shafreen, B., Venugopal, A. et al. (2009) Human Protein Reference Database-2009 update. Nucleic Acids Res., 37, D767-D772.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. D767-D772
-
-
Keshava Prasad, T.S.1
Goel, R.2
Kandasamy, K.3
Keerthikumar, S.4
Kumar, S.5
Mathivanan, S.6
Telikicherla, D.7
Raju, R.8
Shafreen, B.9
Venugopal, A.10
-
30
-
-
27744469130
-
High-betweenness proteins in the yeast protein interaction network
-
Joy, M.P., Brock, A., Ingber, D.E. and Huang, S. (2005) High-betweenness proteins in the yeast protein interaction network. J. Biomed. Biotechnol., 2005, 96-103.
-
(2005)
J. Biomed. Biotechnol.
, vol.2005
, pp. 96-103
-
-
Joy, M.P.1
Brock, A.2
Ingber, D.E.3
Huang, S.4
-
31
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis, B.P., Burge, C.B. and Bartel, D.P. (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell, 120, 15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
32
-
-
78650758676
-
Histone H3K27ac separates active from poised enhancers and predicts developmental state
-
Creyghton, M.P., Cheng, A.W., Welstead, G.G., Kooistra, T., Carey, B.W., Steine, E.J., Hanna, J., Lodato, M.A., Frampton, G.M., Sharp, P.A. et al. (2010) Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc. Natl. Acad. Sci. U.S.A., 107, 21931-21936.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 21931-21936
-
-
Creyghton, M.P.1
Cheng, A.W.2
Welstead, G.G.3
Kooistra, T.4
Carey, B.W.5
Steine, E.J.6
Hanna, J.7
Lodato, M.A.8
Frampton, G.M.9
Sharp, P.A.10
-
33
-
-
79951516056
-
A unique chromatin signature uncovers early developmental enhancers in humans
-
Rada-Iglesias, A., Bajpai, R., Swigut, T., Brugmann, S.A., Flynn, R.A. and Wysocka, J. (2011) A unique chromatin signature uncovers early developmental enhancers in humans. Nature, 470, 279-283.
-
(2011)
Nature
, vol.470
, pp. 279-283
-
-
Rada-Iglesias, A.1
Bajpai, R.2
Swigut, T.3
Brugmann, S.A.4
Flynn, R.A.5
Wysocka, J.6
-
34
-
-
84929138298
-
The molecular phenotype of endocapillary proliferation: Novel therapeutic targets for IgA nephropathy
-
Hodgin, J.B., Berthier, C.C., John, R., Grone, E., Porubsky, S., Gröne, H.-J., Herzenberg, A.M., Scholey, J.W., Hladunewich, M., Cattran, D.C. et al. (2014) The molecular phenotype of endocapillary proliferation: novel therapeutic targets for IgA nephropathy. PLoS One, 9, e103413.
-
(2014)
PLoS One
, vol.9
, pp. e103413
-
-
Hodgin, J.B.1
Berthier, C.C.2
John, R.3
Grone, E.4
Porubsky, S.5
Gröne, H.-J.6
Herzenberg, A.M.7
Scholey, J.W.8
Hladunewich, M.9
Cattran, D.C.10
-
35
-
-
84876041065
-
TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease
-
Yoneno, K., Hisamatsu, T., Shimamura, K., Kamada, N., Ichikawa, R., Kitazume, M.T., Mori, M., Uo, M., Namikawa, Y., Matsuoka, K. et al. (2013) TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease. Immunology, 139, 19-29.
-
(2013)
Immunology
, vol.139
, pp. 19-29
-
-
Yoneno, K.1
Hisamatsu, T.2
Shimamura, K.3
Kamada, N.4
Ichikawa, R.5
Kitazume, M.T.6
Mori, M.7
Uo, M.8
Namikawa, Y.9
Matsuoka, K.10
-
36
-
-
84881612311
-
Mutation in the SYNJ1 gene associated with autosomal recessive, early-onset parkinsonism
-
Quadri, M., Fang, M., Picillo, M., Olgiati, S., Breedveld, G.J., Graafland, J., Wu, B., Xu, F., Erro, R., Amboni, M. et al. (2013) Mutation in the SYNJ1 gene associated with autosomal recessive, early-onset parkinsonism. Hum. Mutat., 34, 1208-1215.
-
(2013)
Hum. Mutat.
, vol.34
, pp. 1208-1215
-
-
Quadri, M.1
Fang, M.2
Picillo, M.3
Olgiati, S.4
Breedveld, G.J.5
Graafland, J.6
Wu, B.7
Xu, F.8
Erro, R.9
Amboni, M.10
-
37
-
-
84926252389
-
Synaptojanin 1 mutation in Parkinson's disease brings further insight into the neuropathological mechanisms
-
Drouet, V. and Lesage, S. (2014) Synaptojanin 1 Mutation in Parkinson's Disease Brings Further Insight into the Neuropathological Mechanisms. Biomed Res. Int., 2014, 289728.
-
(2014)
Biomed Res. Int.
, vol.2014
, pp. 289728
-
-
Drouet, V.1
Lesage, S.2
-
38
-
-
84920853683
-
PLD3 is accumulated on neuritic plaques in Alzheimer's disease brains
-
Satoh, J.-I., Kino, Y., Yamamoto, Y., Kawana, N., Ishida, T., Saito, Y. and Arima, K. (2014) PLD3 is accumulated on neuritic plaques in Alzheimer's disease brains. Alzheimers. Res. Ther., 6, 70.
-
(2014)
Alzheimers. Res. Ther.
, vol.6
, pp. 70
-
-
Satoh, J.-I.1
Kino, Y.2
Yamamoto, Y.3
Kawana, N.4
Ishida, T.5
Saito, Y.6
Arima, K.7
-
39
-
-
84892819277
-
Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease
-
Cruchaga, C., Karch, C.M., Jin, S.C., Benitez, B. a, Cai, Y., Guerreiro, R., Harari, O., Norton, J., Budde, J., Bertelsen, S. et al. (2014) Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease. Nature, 505, 550-554.
-
(2014)
Nature
, vol.505
, pp. 550-554
-
-
Cruchaga, C.1
Karch, C.M.2
Jin, S.C.3
Benitez, B.A.4
Cai, Y.5
Guerreiro, R.6
Harari, O.7
Norton, J.8
Budde, J.9
Bertelsen, S.10
-
40
-
-
84884297351
-
An expression atlas of human primary cells: Inference of gene function from coexpression networks
-
Mabbott, N.A., Baillie, J.K., Brown, H., Freeman, T.C. and Hume, D.A. (2013) An expression atlas of human primary cells: inference of gene function from coexpression networks. BMC Genomics, 14, 632.
-
(2013)
BMC Genomics
, vol.14
, pp. 632
-
-
Mabbott, N.A.1
Baillie, J.K.2
Brown, H.3
Freeman, T.C.4
Hume, D.A.5
-
41
-
-
81055125748
-
PLD4 is involved in phagocytosis of microglia: Expression and localization changes of PLD4 are correlated with activation state of microglia
-
Otani, Y., Yamaguchi, Y., Sato, Y., Furuichi, T., Ikenaka, K., Kitani, H. and Baba, H. (2011) PLD4 is involved in phagocytosis of microglia: Expression and localization changes of PLD4 are correlated with activation state of microglia. PLoS One, 6, e27544.
-
(2011)
PLoS One
, vol.6
, pp. e27544
-
-
Otani, Y.1
Yamaguchi, Y.2
Sato, Y.3
Furuichi, T.4
Ikenaka, K.5
Kitani, H.6
Baba, H.7
-
42
-
-
84875275699
-
Human diseases through the lens of network biology
-
Furlong, L.I. (2013) Human diseases through the lens of network biology. Trends Genet., 29, 150-159.
-
(2013)
Trends Genet.
, vol.29
, pp. 150-159
-
-
Furlong, L.I.1
-
43
-
-
84862204864
-
The role of the 3′ untranslated region in post-transcriptional regulation of protein expression in mammalian cells
-
Matoulkova, E., Michalova, E., Vojtesek, B. and Hrstka, R. (2012) The role of the 3′ untranslated region in post-transcriptional regulation of protein expression in mammalian cells. RNA Biol., 9, 563-576.
-
(2012)
RNA Biol.
, vol.9
, pp. 563-576
-
-
Matoulkova, E.1
Michalova, E.2
Vojtesek, B.3
Hrstka, R.4
-
44
-
-
70350469040
-
The relationship between the evolution of microRNA targets and the length of their UTRs
-
Cheng, C., Bhardwaj, N. and Gerstein, M. (2009) The relationship between the evolution of microRNA targets and the length of their UTRs. BMC Genomics, 10, 431.
-
(2009)
BMC Genomics
, vol.10
, pp. 431
-
-
Cheng, C.1
Bhardwaj, N.2
Gerstein, M.3
-
45
-
-
33845315897
-
MicroRNAs preferentially target the genes with high transcriptional regulation complexity
-
Cui, Q., Yu, Z., Pan, Y., Purisima, E.O. and Wang, E. (2007) MicroRNAs preferentially target the genes with high transcriptional regulation complexity. Biochem. Biophys. Res. Commun., 352, 733-738.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.352
, pp. 733-738
-
-
Cui, Q.1
Yu, Z.2
Pan, Y.3
Purisima, E.O.4
Wang, E.5
-
46
-
-
80052266532
-
MicroRNAs can generate thresholds in target gene expression
-
Mukherji, S., Ebert, M.S., Zheng, G.X.Y., Tsang, J.S., Sharp, P.A. and van Oudenaarden, A. (2011) MicroRNAs can generate thresholds in target gene expression. Nat. Genet., 43, 854-859.
-
(2011)
Nat. Genet.
, vol.43
, pp. 854-859
-
-
Mukherji, S.1
Ebert, M.S.2
Zheng, G.X.Y.3
Tsang, J.S.4
Sharp, P.A.5
Van Oudenaarden, A.6
-
47
-
-
28944439309
-
Animal microRNAs confer robustness to gene expression and have a significant impact on 3UTR evolution
-
Stark, A., Brennecke, J., Bushati, N., Russell, R.B. and Cohen, S.M. (2005) Animal microRNAs confer robustness to gene expression and have a significant impact on 3UTR evolution. Cell, 123, 1133-1146.
-
(2005)
Cell
, vol.123
, pp. 1133-1146
-
-
Stark, A.1
Brennecke, J.2
Bushati, N.3
Russell, R.B.4
Cohen, S.M.5
-
48
-
-
84878496035
-
From mouse to human: Evolutionary genomics analysis of human orthologs of essential genes
-
Georgi, B., Voight, B.F. and Bućan, M. (2013) From Mouse to Human: Evolutionary Genomics Analysis of Human Orthologs of Essential Genes. PLoS Genet., 9, e1003484.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003484
-
-
Georgi, B.1
Voight, B.F.2
Bućan, M.3
-
49
-
-
84923377359
-
Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer/'s disease
-
Gjoneska, E., Pfenning, A.R., Mathys, H., Quon, G., Kundaje, A., Tsai, L.-H. and Kellis, M. (2015) Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer/'s disease. Nature, 518, 365-369.
-
(2015)
Nature
, vol.518
, pp. 365-369
-
-
Gjoneska, E.1
Pfenning, A.R.2
Mathys, H.3
Quon, G.4
Kundaje, A.5
Tsai, L.-H.6
Kellis, M.7
-
50
-
-
77957970301
-
Epigenetic modifications and human disease
-
Portela, A. and Esteller, M. (2010) Epigenetic modifications and human disease. Nat. Biotechnol., 28, 1057-1068.
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 1057-1068
-
-
Portela, A.1
Esteller, M.2
-
51
-
-
84924059300
-
Mammalian transcriptional hotspots are enriched for tissue specific enhancers near cell type specific highly expressed genes and are predicted to act as transcriptional activator hubs
-
Joshi, A. (2014) Mammalian transcriptional hotspots are enriched for tissue specific enhancers near cell type specific highly expressed genes and are predicted to act as transcriptional activator hubs. BMC Bioinformatics, 15, 6591.
-
(2014)
BMC Bioinformatics
, vol.15
, pp. 6591
-
-
Joshi, A.1
-
52
-
-
84928207423
-
Convergence of developmental and oncogenic signaling pathways at transcriptional super-enhancers
-
Hnisz, D., Schuijers, J., Lin, C.Y., Weintraub, A.S., Abraham, B.J., Lee, T.I., Bradner, J.E. and Young, R.A. (2015) Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers. Mol. Cell, 58, 325-370.
-
(2015)
Mol. Cell
, vol.58
, pp. 325-370
-
-
Hnisz, D.1
Schuijers, J.2
Lin, C.Y.3
Weintraub, A.S.4
Abraham, B.J.5
Lee, T.I.6
Bradner, J.E.7
Young, R.A.8
|