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Volumn 9, Issue 2, 2014, Pages

Functionally enigmatic genes: A case study of the brain ignorome

Author keywords

[No Author keywords available]

Indexed keywords

3' UNTRANSLATED REGION; ADULT; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; CASE STUDY; CEREBELLUM; D5BUC30E GENE; DENTATE GYRUS; DZANK1 GENE; ELMOD1 GENE; FAM123C GENE; FEMALE; FRRS1L GENE; GABRB1 GENE; GENE; GENE EXPRESSION; GENE FUNCTION; GENETIC ASSOCIATION; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA2 REGION; HIPPOCAMPAL CA3 REGION; HYPOTHALAMUS; MALE; MISSENSE MUTATION; MOUSE; NEOCORTEX; NONHUMAN; OLFACTORY BULB; PROTEIN DOMAIN; PURKINJE CELL; RNA SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM; TMEM88B GENE;

EID: 84895734902     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088889     Document Type: Article
Times cited : (72)

References (57)
  • 1
    • 0037303467 scopus 로고    scopus 로고
    • Life cycles of successful genes
    • DOI 10.1016/S0168-9525(02)00014-8, PII S0168952502000148
    • Hoffmann R, Valencia A (2003) Life cycles of successful genes. Trends Genet 19: 79-81. (Pubitemid 36120663)
    • (2003) Trends in Genetics , vol.19 , Issue.2 , pp. 79-81
    • Hoffmann, R.1    Valencia, A.2
  • 2
    • 35748957801 scopus 로고    scopus 로고
    • Power-law-like distributions in biomedical publications and research funding
    • Su AI, Hogenesch JB (2007) Power-law-like distributions in biomedical publications and research funding. Genome Biol 8: 404.
    • (2007) Genome Biol , vol.8 , pp. 404
    • Su, A.I.1    Hogenesch, J.B.2
  • 4
    • 16544388283 scopus 로고    scopus 로고
    • Brain Gene Expression: Genomics and Genetics
    • DOI 10.1016/S0074-7742(04)60003-1, PII S0074774204600031, DNA Arrays in Neurobiology
    • Chesler EJ, Williams RW (2004) Brain gene expression: genomics and genetics. Int Rev Neurobiol 60: 59-95. (Pubitemid 39752430)
    • (2004) International Review of Neurobiology , vol.60 , pp. 59-95
    • Chesler, E.J.1    Williams, R.W.2
  • 5
    • 57149090077 scopus 로고    scopus 로고
    • Dissection of a QTL hotspot on mouse distal chromosome 1 that modulates neurobehavioral phenotypes and gene expression
    • Mozhui K, Ciobanu DC, Schikorski T, Wang X, Lu L, et al. (2008) Dissection of a QTL hotspot on mouse distal chromosome 1 that modulates neurobehavioral phenotypes and gene expression. PLoS Genet 4: e1000260.
    • (2008) PLoS Genet , vol.4
    • Mozhui, K.1    Ciobanu, D.C.2    Schikorski, T.3    Wang, X.4    Lu, L.5
  • 6
    • 77957862149 scopus 로고    scopus 로고
    • A transposon in Comt generates mRNA variants and causes widespread expression and behavioral differences among mice
    • Li Z, Mulligan MK, Wang X, Miles MF, Lu L, et al. (2010) A transposon in Comt generates mRNA variants and causes widespread expression and behavioral differences among mice. PLoS One 5: e12181.
    • (2010) PLoS One , vol.5
    • Li, Z.1    Mulligan, M.K.2    Wang, X.3    Miles, M.F.4    Lu, L.5
  • 7
    • 77957860297 scopus 로고    scopus 로고
    • Genetics of the hippocampal transcriptome in mouse: A systematic survey and online neurogenomics resource
    • Overall RW, Kempermann G, Peirce J, Lu L, Goldowitz D, et al. (2009) Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource. Front Neurosci 3: 55.
    • (2009) Front Neurosci , vol.3 , pp. 55
    • Overall, R.W.1    Kempermann, G.2    Peirce, J.3    Lu, L.4    Goldowitz, D.5
  • 11
  • 13
    • 1542613784 scopus 로고    scopus 로고
    • TAFA: A novel secreted family with conserved cysteine residues and restricted expression in the brain
    • DOI 10.1016/j.ygeno.2003.10.006, PII S088875430300332X
    • Tom Tang Y, Emtage P, Funk WD, Hu T, Arterburn M, et al. (2004) TAFA: a novel secreted family with conserved cysteine residues and restricted expression in the brain. Genomics 83: 727-734. (Pubitemid 38340813)
    • (2004) Genomics , vol.83 , Issue.4 , pp. 727-734
    • Tom, T.Y.1    Emtage, P.2    Funk, W.D.3    Hu, T.4    Arterburn, M.5    Park, E.E.J.6    Rupp, F.7
  • 14
    • 33846252240 scopus 로고    scopus 로고
    • Genome-wide atlas of gene expression in the adult mouse brain
    • Lein ES, Hawrylycz MJ, Ao N, Ayres M, Bensinger A, et al. (2007) Genome-wide atlas of gene expression in the adult mouse brain. Nature 445: 168-176.
    • (2007) Nature , vol.445 , pp. 168-176
    • Lein, E.S.1    Hawrylycz, M.J.2    Ao, N.3    Ayres, M.4    Bensinger, A.5
  • 15
    • 57449114979 scopus 로고    scopus 로고
    • The InterPro database and tools for protein domain analysis
    • Chapter 2: Unit 2 7
    • Mulder NJ, Apweiler R (2008) The InterPro database and tools for protein domain analysis. Curr Protoc Bioinformatics Chapter 2: Unit 2 7.
    • (2008) Curr Protoc Bioinformatics
    • Mulder, N.J.1    Apweiler, R.2
  • 17
    • 7444261393 scopus 로고    scopus 로고
    • WormBase as an integrated platform for the C. elegans ORFeome
    • Chen N, Lawson D, Bradnam K, Harris TW, Stein LD (2004) WormBase as an integrated platform for the C. elegans ORFeome. Genome Res 14: 2155-2161. (Pubitemid 39440198)
    • (2004) Genome Research , vol.14 , Issue.10 B , pp. 2155-2161
    • Chen, N.1    Lawson, D.2    Bradnam, K.3    Harris, T.W.4    Stein, L.D.5
  • 18
    • 0038522873 scopus 로고    scopus 로고
    • GeneMerge - Post-genomic analysis, data mining, and hypothesis testing
    • DOI 10.1093/bioinformatics/btg114
    • Castillo-Davis CI, Hartl DL (2003) GeneMerge-post-genomic analysis, data mining, and hypothesis testing. Bioinformatics 19: 891-892. (Pubitemid 36582407)
    • (2003) Bioinformatics , vol.19 , Issue.7 , pp. 891-892
    • Castillo-Davis, C.I.1    Hartl, D.L.2
  • 20
    • 12344257752 scopus 로고    scopus 로고
    • GeneNetwork: An interactive tool for reconstruction of genetic networks using microarray data
    • Wu CC, Huang HC, Juan HF, Chen ST (2004) GeneNetwork: an interactive tool for reconstruction of genetic networks using microarray data. Bioinformatics 20: 3691-3693.
    • (2004) Bioinformatics , vol.20 , pp. 3691-3693
    • Wu, C.C.1    Huang, H.C.2    Juan, H.F.3    Chen, S.T.4
  • 21
    • 84866420982 scopus 로고    scopus 로고
    • Systems genetics of metabolism: The use of the BXD murine reference panel for multiscalar integration of traits
    • Andreux PA, Williams EG, Koutnikova H, Houtkooper RH, Champy MF, et al. (2012) Systems genetics of metabolism: the use of the BXD murine reference panel for multiscalar integration of traits. Cell 150: 1287-1299.
    • (2012) Cell , vol.150 , pp. 1287-1299
    • Andreux, P.A.1    Williams, E.G.2    Koutnikova, H.3    Houtkooper, R.H.4    Champy, M.F.5
  • 22
    • 70149124338 scopus 로고    scopus 로고
    • Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics
    • Koutnikova H, Laakso M, Lu L, Combe R, Paananen J, et al. (2009) Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics. PLoS Genet 5: e1000591.
    • (2009) PLoS Genet , vol.5
    • Koutnikova, H.1    Laakso, M.2    Lu, L.3    Combe, R.4    Paananen, J.5
  • 23
    • 0033661859 scopus 로고    scopus 로고
    • Quantitative trait loci for acute behavioral sensitivity to paraoxon
    • Risinger FO, Quick E, Belknap JK (2000) Quantitative trait loci for acute behavioral sensitivity to paraoxon. Neurotoxicol Teratol 22: 667-674.
    • (2000) Neurotoxicol Teratol , vol.22 , pp. 667-674
    • Risinger, F.O.1    Quick, E.2    Belknap, J.K.3
  • 24
    • 77949344299 scopus 로고    scopus 로고
    • High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains
    • Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, et al. (2010) High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains. Genes Brain Behav 9: 129-159.
    • (2010) Genes Brain Behav , vol.9 , pp. 129-159
    • Philip, V.M.1    Duvvuru, S.2    Gomero, B.3    Ansah, T.A.4    Blaha, C.D.5
  • 25
    • 0033555415 scopus 로고    scopus 로고
    • Identification of an acute ethanol response quantitative trait locus on mouse chromosome 2
    • Demarest K, McCaughran J Jr, Mahjubi E, Cipp L, Hitzemann R (1999) Identification of an acute ethanol response quantitative trait locus on mouse chromosome 2. J Neurosci 19: 549-561. (Pubitemid 29036006)
    • (1999) Journal of Neuroscience , vol.19 , Issue.2 , pp. 549-561
    • Demarest, K.1    McCaughran Jr., J.2    Mahjubi, E.3    Cipp, L.4    Hitzemann, R.5
  • 26
    • 0030297902 scopus 로고    scopus 로고
    • Quantitative trait loci contributing to phencyclidine-induced and amphetamine-induced locomotor behavior in inbred mice
    • DOI 10.1016/S0893-133X(96)00058-9, PII S0893133X96000589
    • Alexander RC, Wright R, Freed W (1996) Quantitative trait loci contributing to phencyclidine-induced and amphetamine-induced locomotor behavior in inbred mice. Neuropsychopharmacology 15: 484-490. (Pubitemid 26386276)
    • (1996) Neuropsychopharmacology , vol.15 , Issue.5 , pp. 484-490
    • Alexander, R.C.1    Wright, R.2    Freed, W.3
  • 27
    • 84860430569 scopus 로고    scopus 로고
    • Mutations of the mouse ELMO domain containing 1 gene (Elmod1) link small GTPase signaling to actin cytoskeleton dynamics in hair cell stereocilia
    • Johnson KR, Longo-Guess CM, Gagnon LH (2012) Mutations of the mouse ELMO domain containing 1 gene (Elmod1) link small GTPase signaling to actin cytoskeleton dynamics in hair cell stereocilia. PLoS One 7: e36074.
    • (2012) PLoS One , vol.7
    • Johnson, K.R.1    Longo-Guess, C.M.2    Gagnon, L.H.3
  • 28
    • 0035910270 scopus 로고    scopus 로고
    • Predicting transmembrane protein topology with a hidden Markov model: Application to complete genomes
    • DOI 10.1006/jmbi.2000.4315
    • Krogh A, Larsson B, von Heijne G, Sonnhammer EL (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J Mol Biol 305: 567-580. (Pubitemid 33032862)
    • (2001) Journal of Molecular Biology , vol.305 , Issue.3 , pp. 567-580
    • Krogh, A.1    Larsson, B.2    Von Heijne, G.3    Sonnhammer, E.L.L.4
  • 29
    • 0029560462 scopus 로고
    • Genetic analysis of the corticosterone response to ethanol in BXD recombinant inbred mice
    • DOI 10.1037/0735-7044.109.6.1199
    • Roberts AJ, Phillips TJ, Belknap JK, Finn DA, Keith LD (1995) Genetic analysis of the corticosterone response to ethanol in BXD recombinant inbred mice. Behav Neurosci 109: 1199-1208. (Pubitemid 26001483)
    • (1995) Behavioral Neuroscience , vol.109 , Issue.6 , pp. 1199-1208
    • Roberts, A.J.1    Phillips, T.J.2    Belknap, J.K.3    Finn, D.A.4    Keith, L.D.5
  • 31
    • 0024398994 scopus 로고
    • The genetics of tasting in mice. VI. Saccharin, acesulfame, dulcin and sucrose
    • Lush IE (1989) The genetics of tasting in mice. VI. Saccharin, acesulfame, dulcin and sucrose. Genet Res 53: 95-99.
    • (1989) Genet Res , vol.53 , pp. 95-99
    • Lush, I.E.1
  • 33
    • 0025132860 scopus 로고
    • Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family
    • DOI 10.1016/0896-6273(90)90090-3
    • Ernfors P, Wetmore C, Olson L, Persson H (1990) Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family. Neuron 5: 511-526. (Pubitemid 20369587)
    • (1990) Neuron , vol.5 , Issue.4 , pp. 511-526
    • Ernfors, P.1    Wetmore, C.2    Olson, L.3    Persson, H.4
  • 34
    • 0029854439 scopus 로고    scopus 로고
    • Expression of mRNAs for neurotrophic factors (NGF, BDNF, NT-3, and GDNF) and their receptors (p75NGFR, trkA, trkB, and trkC) in the adult human peripheral nervous system and nonneural tissues
    • Yamamoto M, Sobue G, Yamamoto K, Terao S, Mitsuma T (1996) Expression of mRNAs for neurotrophic factors (NGF, BDNF, NT-3, and GDNF) and their receptors (p75NGFR, trkA, trkB, and trkC) in the adult human peripheral nervous system and nonneural tissues. Neurochem Res 21: 929-938.
    • (1996) Neurochem Res , vol.21 , pp. 929-938
    • Yamamoto, M.1    Sobue, G.2    Yamamoto, K.3    Terao, S.4    Mitsuma, T.5
  • 35
    • 44449119466 scopus 로고    scopus 로고
    • Two patients with balanced translocations and autistic disorder: CSMD3 as a candidate gene for autism found in their common 8q23 breakpoint area
    • DOI 10.1038/ejhg.2008.7, PII EJHG20087
    • Floris C, Rassu S, Boccone L, Gasperini D, Cao A, et al. (2008) Two patients with balanced translocations and autistic disorder: CSMD3 as a candidate gene for autism found in their common 8q23 breakpoint area. Eur J Hum Genet 16: 696-704. (Pubitemid 351753366)
    • (2008) European Journal of Human Genetics , vol.16 , Issue.6 , pp. 696-704
    • Floris, C.1    Rassu, S.2    Boccone, L.3    Gasperini, D.4    Cao, A.5    Crisponi, L.6
  • 38
    • 64149105182 scopus 로고    scopus 로고
    • Genetic control of human brain transcript expression in Alzheimer disease
    • Webster JA, Gibbs JR, Clarke J, Ray M, Zhang W, et al. (2009) Genetic control of human brain transcript expression in Alzheimer disease. Am J Hum Genet 84: 445-458.
    • (2009) Am J Hum Genet , vol.84 , pp. 445-458
    • Webster, J.A.1    Gibbs, J.R.2    Clarke, J.3    Ray, M.4    Zhang, W.5
  • 39
    • 40849118045 scopus 로고    scopus 로고
    • Taip2 is a novel cell death-related gene expressed in the brain during development
    • Yamada K, Akiyama N, Yamada S, Tanaka H, Saito S, et al. (2008) Taip2 is a novel cell death-related gene expressed in the brain during development. Biochem Biophys Res Commun 369: 426-431.
    • (2008) Biochem Biophys Res Commun , vol.369 , pp. 426-431
    • Yamada, K.1    Akiyama, N.2    Yamada, S.3    Tanaka, H.4    Saito, S.5
  • 40
    • 65849214710 scopus 로고    scopus 로고
    • Clinical, genetic, molecular, and pathophysiological insights into spinocerebellar ataxia type 1
    • Matilla-Duenas A, Goold R, Giunti P (2008) Clinical, genetic, molecular, and pathophysiological insights into spinocerebellar ataxia type 1. Cerebellum 7: 106-114.
    • (2008) Cerebellum , vol.7 , pp. 106-114
    • Matilla-Duenas, A.1    Goold, R.2    Giunti, P.3
  • 43
    • 32944476638 scopus 로고    scopus 로고
    • Disruption of TCBA1 associated with a de novo t(1;6)(q32.2;q22.3) presenting in a child with developmental delay and recurrent infections
    • DOI 10.1136/jmg.2004.029660
    • Yue Y, Stout K, Grossmann B, Zechner U, Brinckmann A, et al. (2006) Disruption of TCBA1 associated with a de novo t(1;6)(q32.2;q22.3) presenting in a child with developmental delay and recurrent infections. J Med Genet 43: 143-147. (Pubitemid 43259627)
    • (2006) Journal of Medical Genetics , vol.43 , Issue.2 , pp. 143-147
    • Yue, Y.1    Stout, K.2    Grossmann, B.3    Zechner, U.4    Brinckmann, A.5    White, C.6    Pilz, D.T.7    Haaf, T.8
  • 44
    • 27644486344 scopus 로고    scopus 로고
    • Molecular characterization of a t(2;6) balanced translocation that is associated with a complex phenotype and leads to truncation of the TCBA1 gene
    • DOI 10.1002/humu.20235
    • Bocciardi R, Giorda R, Marigo V, Zordan P, Montanaro D, et al. (2005) Molecular characterization of a t(2;6) balanced translocation that is associated with a complex phenotype and leads to truncation of the TCBA1 gene. Hum Mutat 26: 426-436. (Pubitemid 41572449)
    • (2005) Human Mutation , vol.26 , Issue.5 , pp. 426-436
    • Bocciardi, R.1    Giorda, R.2    Marigo, V.3    Zordan, P.4    Montanaro, D.5    Gimelli, S.6    Seri, M.7    Lerone, M.8    Ravazzolo, R.9    Gimelli, G.10
  • 47
    • 4644236043 scopus 로고    scopus 로고
    • Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease
    • DOI 10.1016/S0140-6736(04)17104-3, PII S0140673604171043
    • Ibanez P, Bonnet AM, Debarges B, Lohmann E, Tison F, et al. (2004) Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease. Lancet 364: 1169-1171. (Pubitemid 39296605)
    • (2004) Lancet , vol.364 , Issue.9440 , pp. 1169-1171
    • Ibanez, P.1    Bonnet, A.-M.2    Debarges, B.3    Lohmann, E.4    Tison, F.5    Pollak, P.6    Agid, Y.7    Durr, A.8    Brice, P.A.9
  • 49
  • 50
    • 70149102674 scopus 로고    scopus 로고
    • Gene expression in the mouse eye: An online resource for genetics using 103 strains of mice
    • Geisert EE, Lu L, Freeman-Anderson NE, Templeton JP, Nassr M, et al. (2009) Gene expression in the mouse eye: an online resource for genetics using 103 strains of mice. Mol Vis 15: 1730-1763.
    • (2009) Mol Vis , vol.15 , pp. 1730-1763
    • Geisert, E.E.1    Lu, L.2    Freeman-Anderson, N.E.3    Templeton, J.P.4    Nassr, M.5
  • 51
    • 76249090489 scopus 로고    scopus 로고
    • BioGPS: An extensible and customizable portal for querying and organizing gene annotation resources
    • Wu C, Orozco C, Boyer J, Leglise M, Goodale J, et al. (2009) BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources. Genome Biol 10: R130.
    • (2009) Genome Biol , vol.10
    • Wu, C.1    Orozco, C.2    Boyer, J.3    Leglise, M.4    Goodale, J.5
  • 53
    • 1542475298 scopus 로고    scopus 로고
    • In silico analysis indicates a similar gene expression pattern between human brain and testis
    • DOI 10.1159/000076290
    • Guo J, Zhu P, Wu C, Yu L, Zhao S, et al. (2003) In silico analysis indicates a similar gene expression pattern between human brain and testis. Cytogenet Genome Res 103: 58-62. (Pubitemid 38353286)
    • (2003) Cytogenetic and Genome Research , vol.103 , Issue.1-2 , pp. 58-62
    • Guo, J.1    Zhu, P.2    Wu, C.3    Yu, L.4    Zhao, S.5    Gu, X.6
  • 54
    • 74249094927 scopus 로고    scopus 로고
    • Detection, validation, and downstream analysis of allelic variation in gene expression
    • Ciobanu DC, Lu L, Mozhui K, Wang X, Jagalur M, et al. (2010) Detection, validation, and downstream analysis of allelic variation in gene expression. Genetics 184: 119-128.
    • (2010) Genetics , vol.184 , pp. 119-128
    • Ciobanu, D.C.1    Lu, L.2    Mozhui, K.3    Wang, X.4    Jagalur, M.5
  • 55
    • 84861179159 scopus 로고    scopus 로고
    • Global patterns of tissue-specific alternative polyadenylation in Drosophila
    • Smibert P, Miura P, Westholm JO, Shenker S, May G, et al. (2012) Global patterns of tissue-specific alternative polyadenylation in Drosophila. Cell Rep 1: 277-289.
    • (2012) Cell Rep , vol.1 , pp. 277-289
    • Smibert, P.1    Miura, P.2    Westholm, J.O.3    Shenker, S.4    May, G.5
  • 57
    • 59949096873 scopus 로고    scopus 로고
    • EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates
    • Vilella AJ, Severin J, Ureta-Vidal A, Heng L, Durbin R, et al. (2009) EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates. Genome Res 19: 327-335.
    • (2009) Genome Res , vol.19 , pp. 327-335
    • Vilella, A.J.1    Severin, J.2    Ureta-Vidal, A.3    Heng, L.4    Durbin, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.