CCR5-dependent activation of mTORC1 regulates translation of inducible NO synthase and COX-2 during encephalomyocarditis virus infection

Journal of Immunology

Volumn 195, Issue 9, 2015, Pages 4406-4414

  Shaheen, Zachary R ^a   Naatz, Aaron ^a   Corbett, John A ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3B7 POLYMERASE; 8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; CHEMOKINE RECEPTOR CCR5; GAMMA INTERFERON; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; VIRUS ENZYME; CCR5 PROTEIN, MOUSE; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ARTICLE; CARDIOVIRUS INFECTION; CONTROLLED STUDY; COX 2 GENE; ENCEPHALOMYOCARDITIS VIRUS INFECTION; ENZYME ACTIVATION; GENE; GENE EXPRESSION; INOS GENE; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; TRANSLATION REGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL LINE; DEFICIENCY; DRUG EFFECTS; ENCEPHALOMYOCARDITIS VIRUS; GENE EXPRESSION REGULATION; GENETICS; HOST PATHOGEN INTERACTION; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; PHYSIOLOGY; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIROLOGY; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL LINE; CELLS, CULTURED; CYCLOOXYGENASE 2; ENCEPHALOMYOCARDITIS VIRUS; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; INTERFERON-GAMMA; MACROPHAGES; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MULTIPROTEIN COMPLEXES; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN BIOSYNTHESIS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, CCR5; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TOR SERINE-THREONINE KINASES;

EID: 84945162363     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1500704     Document Type: Article

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