Dendritic cell stimulation by mycobacterial Hsp70 is mediated through CCR5

Science

Volumn 314, Issue 5798, 2006, Pages 454-458

  Floto, R Andres ^a   MacAry, Paul A ^a,b   Boname, Jessica M ^a   Mien, Tan Suet ^c   Kampmann, Beate ^d   Hair, James R ^a   Huey, Oh Seen ^b   Houben, Edith N G ^e   Pieters, Jean ^e   Day, Cheryl ^f   Oehlmann, Wulf ^g   Singh, Mahavir ^g   Smith, Kenneth G C ^a   Lehner, Paul J ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF BASEL   (Switzerland)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g LIONEX DIAGNOSTICS AND THERAPEUTICS GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; BACTERIA; IMMUNIZATION; PATHOLOGY; PHYSIOLOGY; PROTEINS;

CELL AGGREGATION; DENDRITIC CELLS; IMMUNOTHERAPY; MYCOBACTERIAL INFECTION; TUBERCULOSIS;

CELLS;

CHEMOKINE RECEPTOR CCR5; HEAT SHOCK PROTEIN 70; PATTERN RECOGNITION RECEPTOR;

ANTIGEN; BACTERIAL DISEASE; BACTERIUM; HEAT SHOCK; HOST; IMMUNE RESPONSE; PATHOGEN; PROTEIN;

ARTICLE; CANCER IMMUNOTHERAPY; CELL AGGREGATION; CELL STIMULATION; DENDRITIC CELL; IMMUNE RESPONSE; IMMUNOPATHOLOGY; MYCOBACTERIOSIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; T LYMPHOCYTE; TUBERCULOSIS;

BACTERIA (MICROORGANISMS);

EID: 33750353443     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1133515     Document Type: Article

References (21)

1. J. L. Flynn, J. Chan, Trends Microbiol. 13, 98 (2005).
2. J. L. Flynn, J. Chan, Annu. Rev. Immunol. 19, 93 (2001).
3. Y. Wang et al., J. Immunol. 169, 2422 (2002).
4. M. J. Gething, J. Sambrook, Nature 355, 33 (1992).
5. P. Srivastava, Annu. Rev. Immunol. 20, 395 (2002).
6. P. A. MacAry et al., Immunity 20, 95 (2004).
7. M. Baba et al., Proc. Natl. Acad. Sci. U.S.A. 96, 5698 (1999).
8. M. Benkirane, D. Y. Jin, R. F. Chun, R. A. Koup, K. T. Jeang, J. Biol. Chem. 272, 30603 (1997).
9. J. E. Hildreth, F. M. Gotch, P. D. Hildreth, A. J. McMichael, Eur. J. Immunol. 13, 202 (1983).
10. P. Revy, M. Sospedra, B. Barbour, A. Trautmann, Nat. Immunol. 2, 925 (2001).
11. M. L. Dustin, T. G. Bivona, M. R. Philips, Nat. Immunol. 5, 363 (2004).
12. B. Kampmann et al., J. Infect. Dis. 182, 895 (2000).
13. K. A. Bodnar, N. V. Serbina, J. L. Flynn, Infect. Immun. 69, 800 (2001).
14. J. G. Cyster, Annu. Rev. Immunol. 23, 127 (2005).
15. M. Nieto et al., J. Exp. Med. 186, 153 (1997).
16. F. Castellino et al., Nature 440, 890 (2006).
17. S. A. Luther, J. G. Cyster, Nat. Immunol. 2, 102 (2001).
18. T. Dragic et al., Nature 381, 667 (1996).
19. J. Aliberti et al., Nat. Immunol. 4, 485 (2003).
20. E. de Silva, M. P. Stumpf, FEMS Microbiol. Lett. 241, 1 (2004).
21. -/- mice. Funded by the Wellcome Trust (P.J.L.), the Medical Research Council (R.A.F.), the Swiss National Science Foundation (J.P.), and FEBS (E.H.). P.J.L. holds a Lister Institute Research Prize.