The significance of T cells, B cells, antibodies and macrophages against encephalomyocarditis (EMC)-D virus-induced diabetes in mice

Archives of Virology

Volumn 153, Issue 7, 2008, Pages 1223-1231

  Kounoue, Etsushi ^a,b   Izumi, Ken Ichi ^a,c   Ogawa, Shuichiro ^a   Kondo, Shiori ^a,c   Katsuta, Hitoshi ^a   Akashi, Tomoyuki ^a   Niho, Yoshiyuki ^a   Harada, Mine ^a   Tamiya, Sadafumi ^a   Kurisaki, Hironori ^a   Nagafuchi, Seiho ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b Kounoue Naika Clinic   (Japan)

^c MATSUYAMA RED CROSS HOSPITAL   (Japan)

Author keywords

B cells; Diabetes; Encephalomyocarditis virus; Macrophages; T cells

Indexed keywords

INTERFERON; VIRUS ANTIBODY;

ANIMAL; ARTICLE; BLOOD; CARDIOVIRUS INFECTION; DBA MOUSE; ENCEPHALOMYOCARDITIS VIRUS; GLUCOSE BLOOD LEVEL; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE; MACROPHAGE; MALE; MOUSE; NUDE MOUSE; PROPIONIBACTERIUM ACNES; SERODIAGNOSIS;

ANIMALS; ANTIBODIES, VIRAL; BLOOD GLUCOSE; CARDIOVIRUS INFECTIONS; DIABETES MELLITUS, TYPE 1; ENCEPHALOMYOCARDITIS VIRUS; INTERFERONS; LYMPHOCYTES; MACROPHAGES; MALE; MICE; MICE, INBRED DBA; MICE, NUDE; NEUTRALIZATION TESTS; PROPIONIBACTERIUM ACNES;

ENCEPHALOMYOCARDITIS VIRUS; MUS; MUS MUSCULUS; PROPIONIBACTERIUM ACNES;

EID: 45849089915     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00705-008-0106-x     Document Type: Article

References (49)

1. Todd JA, Wicker LS (2001) Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models. Immunity 15:387-396
2. Yoon JW (1990) The role of viruses and environmental factors in the induction of diabetes. Current Top Microbiol Immunol 164:95-123
3. Imagawa A, Hanafusa T, Miyagawa J, Matsuzawa Y (2000) A novel subtype of type 1 diabetes mellitus characterized by a rapid onset and an absence of diabetes related antibodies. N Engl J Med 342:301-307
4. Imagawa A, Hanafusa T, Makino H, Miyagawa JI, Juto P (2005) High titres of IgA antibodies to enterovirus in fulminant type-1 diabetes. Diabetologia 48:290-293
5. Jun HS, Yoon JW (2003) A new look at viruses in type 1 diabetes. Diab Met Res Rev 19:8-31
6. Yoon JW, Austin M, Onodera T, Notkins AL (1979) Virus-induced diabetes mellitus: isolation of a virus from the pancreas of a child with diabetic ketoacidosis. N Engl J Med 300:1173-1179
7. King ML, Shaikh A, Bidwell D, Voller A, Banatvala JE (1983) Coxsackie B-virus specific IgM responses in children with insulin-dependent diabetes mellitus. Lancet I:1397-1399
8. Helfand RF, Howard E, Jr Gary, Freeman CY, Anderson LJ, Pallansch MA, Pitttsburgh Diabetes Research Group (1995) Serologic evidence of an association between enteroviruses and the onset of type 1 diabetes mellitus. J Inf Dis 172:1206-1211
9. Lonnrot M, Salminen K, Knip M, Savola K, Kulmala P, Leinikki P, Hyypia T, Akerblom HK, Hyoty H (2000) Child hood diabetes in Finland (DiMe) study group. Enterovirus RNA in serum is a risk factor for beta-cell autoimmunity and clinical type 1 diabetes: a prospective study. J Med Virol 61:214-220
10. Craighead JE, McLane MF (1968) Diabetes mellitus: induction in mice by encephalomyocarditis virus. Science 162:913-914
11. Yoon JW, McClintoock PR, Onodera T, Notkins AL (1980) Virus-induced diabetes mellitus XVIII. Inhibition by a nondiabetogenic variant of encephalomyocarditis virus. J Exp Med 152:878-892
12. Giron DJ, Cohen SJ, Lyons SP, Trombley ML, Gould CL (1983) Virus-induced diabetes mellitus in ICR Swiss mice is age dependent. Infect Immun 41:834-836
13. Yoon JW, Lesniak MA, Fussganger R, Notkins AL (1976) Genetic differences in susceptibility of pancreatic beta cells to virus-induced diabetes mellitus. Nature 264:178-180
14. Jun HD, Yoon JW (2001) The role of viruses in type 1 diabetes: two distinct cellular and molecular pathogenic mechanisms of virus-induced diabetes in animals. Diabetologia 44:271-285
15. Kaptur PE, Thomas DC, Giron DJ (1989) Differing attachment of diabetogenic and nondiabetogenic variants of encephalomyocarditis virus to beta-cells. Diabetes 38:1103-1108
16. Eun HM, Bae YS, Yoon JW (1988) Amino acid differences in capsid protein, VP1, between diabetogenic and nondiabetogenic variants of encephalomyocarditis virus. Virology 163:369-373
17. Hiltunen M, Hyoty H, Knip M, Ilonen J, Reijonen H, Vahasalo P, Roivainene M, Lonnorot M, Leinikki P, Hovi T, Akerblom HS, the Childhood Diabetes in Finland (DiMe) Study Group (1997) Islet cell antibody seroconversion in children is temporally associated with enterovirus infection. J Inf Dis 175:554-560
18. Andreoletti L, Hober D, Hober-Vandenberghe C, Faardy I, Belaich S, Lambert V, Vantyghem M-C, Lefebvre J, Wattre P (1998) Coxsackie B virus infection and β cell autoantibodies in newly diagnosed IDDM adult patients. Clin Diag Virol 9:125-133
19. Buschard K, Hastrup N, Rygaard J (1983) Virus-induced diabetes mellitus in mice and the thymus-dependent immune system. Diabetologia 24:42-46
20. Kawagishi A, Kubosaki A, Takeyama N, Sakudo A, Saeki K, Natsumoto Y, Hayashi T, Onodera T (2003) Analysis of T-cell receptor Vβ gene from infiltrating T cells in insulitis and myocarditis in encephalomyocarditis virus-infected BALB/c mice. Biochem Biophys Res Commun 310:791-795
21. + T lymphocytes possessing cytolytic activity confer protection in the absence of prophylactic antibodies. J Virol 69:4914-4923
22. Kanda T, Koike H, Arai M, Wilson JE, Carthy CM, Yang D, McManus BM, Nagai R, Kobayashi I (1999) Increased severity of viral myocarditis in mice lacking lymphocyte maturation. Int J Cardiol 68:13-22
23. Bigley NJ, Blay RA, Smith RA (1987) Impaired cytokine response in male ICR Swiss mice after infection with D variant of encephalomyocarditis virus. Diabetes 36:1408-1413
24. Hirasawa K, Ogiso Y, Takeda M, Lee MJ, Itagaki S, Doi K (1995) Protective effects of macrophage-derived interferon against encephalomyocarditis virus-induced diabetes mellitus in mice. Lab Anim Sci 45:652-656
25. Baek HS, Yoon JW (1990) Role of macrophages in the pathogenesis of encephalomyocarditis virus-induced diabetes in mice. J Virol 64:5708-5715
26. Hirasawa K, Tsutsui S, Takeda M, Mizutani M, Itagaki S, Doi K (1996) Depletion of Mac1-positive macrophages protects DBA/2 mice from encephalomyocarditis virus-induced myocarditis and diabetes. J Gen Virol 77:737-741
27. Baek HS, Yoon JW (1991) Direct involvement of macrophages in destruction of beta-cells leading to development of diabetes in virus-infected mice. Diabetes 40:1586-1597
28. Kounoue E, Nagafuchi S, Nakamura M, Nakano S, Koga T, Nakayama M, Mituyama M, Niho Y, Takaki R (1987) Encephalomyocarditis (EMC) virus-induced diabetes mellitus prevented by Corynebacterium parvum in mice. Experientia 43:430-431
29. Choi BK, Cho SH, Bai GH, Kim SJ, Hyun BH, Choe YK, Bae YS (2000) Prevention of encephalomyocarditis virus-induced diabetes by live recombinant mycobacterium bovis Bacillus Calmette-Guerin in susceptible mice. Diabetes 49:1459-1467
30. Kitamura D, Roes J, Kuhn R, Rajewsky K (1991) A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene. Nature 350:423-426
31. Akashi T, Nagafuchi S, Anzai K, Kondo S, Kitamura D, Wakana S, Ono J, Kikuchi M, Niho Y, Watanabe T (1997) Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in non-obese diabetic mice. Int Immunol 9:1159-1164
32. Davies JQ, Gordon S (2005) Isolation and culture of murine macrophages. Methods Mol Biol 290:91-103
33. Michl J, Pieczonka MM, Unkeless JC, Silverstein SC (1979) Effects of immobilized immune complexes of Fc- and complement-receptor function in resident and thioglycolate-elicited mouse peritoneal macrophages. J Exp Med 150:607-621
34. Yoon JW, Cha CY, Jordan GW (1983) The role of interferon in virus-induced diabetes. J Infect Dis 147:155-159
35. Kaptur PE, Thomas DC, Giron DJ (1989) The role of interferon in the protection of ICR Swiss male mice by the nondiabetogenic variant of encephalomyocarditis virus against virus-induced diabetes mellitus. J Interferon Res 9:671-678
36. Gould CL, McMannama KG, Bigley NJ, Giron DJ (1985) Exacerbation of the pathogenesis of the diabetogenic variant of encephalomyocarditis virus in mice by interferon. J Interferon Res 5:33-37
37. Flodström M, Maday A, Balakrishna D, Cleary MM, Yoshimura A, Sarvetnick N (2002) Target cell defense prevents the development of diabetes after vial infection. Nat Immunol 3:373-382
38. Ida-Hosonuma M, Iwasaki T, Yoshikawa T, Nagata N, Sto Y, Sata T, Yoneyama M, Fujita T, Taya C, Yonekawa H, Koike S (2005) The alpha/beta interferon response controls tissue tropism and pathogenicity of poliovirus. J Virol 79:4460-4469
39. Ylipaasto P, Klinger K, Lindberg AM, Otonkoski T, Kandolf R, Hovi T, Roivainen M (2004) Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells. Diabetologia 47:225-239
40. Akira S (2006) TLR signaling. Curr Top Microbiol Immunol 311:1-16
41. Hardarson HS, Baker JS, Yang Z, Pureviav E, Huang CH, Alexopoulou L, Li N, Flavell RA, Bowles NE, Vallejo JG (2007) Toll-like receptor 3 is essential component of the innate stress response in virus-induced cardiac injury. Am J Pysiol 292:H251-H258
42. Pichimair A, Schulz O, Tan CP, Naslund TI, Liljestrom P, Weber F, ReC Sousa (2006) RIG-I- mediated antiviral responses to single-stranded RNA bearing 5́-phophates. Science 314:997-1001
43. Kato H, Takeuchi O, Sato S, Yoneyama M, Yamamoto M, Matsui K, Uematsu S, Jung A, Kawai T, Ishi KJ, Yamaguchi O, Otsu K, Tsujimura T, Koh C-S, Cre Sousa, Matsuura LY, Fujita T, Akira S (2006) Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441:101-105
44. Koike S, Taya C, Kurat T, Abe S, Ise I, Yonekawa H, Nomoto A (1991) Transgenic mice susceptible to poliovirus. Proc Natl Acad Sci USA 88:951-955
45. Ren RB, Costantini F, Gorgacz EM, Lee JJ, Racaniello VR (1990) Transgenic mice expressing a human poliovirus receptor: a new model for poliomyelitis. Cell 63:353-362
46. Yoshikawa T, Iwasaki T, Ida-Hosonuma M, Yoneyama M, Fujita T, Horie H, Miyazawa M, Abe S, Simizu B, Koike S (2006) Role of the alpha/beta interferon response in the acquisition of susceptibility to poliovirus by kidney cells in culture. J Virol 80:4313-4325
47. Ohka S, Igarashi H, Nagata N, Sakai M, Koike S, Nochi T, Kiyono H, Nomoto A (2007) Establishment of a poliovirus oral infection system in human poliovirus receptor-expressing transgenic mice that are deficient in alpha/beta interferon receptor. J Virol 81:7902-7912
48. Prejean C, Colamonici OR (2000) Role of the cytoplasmic domains of the type I interferon receptor subunits in signaling. Sem Cancer Biol 10:83-92
49. Kunzi MS, Pitha PM (2003) Interferon targeted genes in host defense. Autoimmunity 36:457-461