MAC inhibitors suppress mitochondrial apoptosis

Biochemical Journal

Volumn 423, Issue 3, 2009, Pages 381-387

  Peixoto, Pablo M ^a   Ryu, Shin Young ^a   Bombrun, Agnes ^b   Antonsson, Bruno ^b   Kinnally, Kathleen W ^a  

^a NEW YORK UNIVERSITY COLLEGE OF DENTISTRY   (United States)

^b MERCK SERONO S A   (Switzerland)

Author keywords

Apoptosis; Cytochrome c release; Interleukin 3; Mitochondrial apoptosis induced channel (MAC); Patch clamp; Staurosporine

Indexed keywords

APOPTOSIS; CYTOCHROME C RELEASE; INTERLEUKIN-3; MITOCHONDRIAL APOPTOSIS-INDUCED CHANNEL (MAC); PATCH-CLAMP; STAUROSPORINE;

CELL MEMBRANES; LIPOSOMES; PHOSPHOLIPIDS;

CELL DEATH;

CYCLOSPORIN A; INTERLEUKIN 13; MITOCHONDRIAL APOPTOSIS INDUCED CHANNEL INHIBITOR; PROTEIN INHIBITOR; STAUROSPORINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL VIABILITY; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME RELEASE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; PATCH CLAMP; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL LINE; CYTOCHROMES C; ENZYME INHIBITORS; INTERLEUKIN-3; ION CHANNELS; MEMBRANE TRANSPORT MODULATORS; MICE; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; RECOMBINANT PROTEINS; STAUROSPORINE;

EID: 70350109543     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20090664     Document Type: Article

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