메뉴 건너뛰기




Volumn 227, Issue 1, 2015, Pages 13-24

STAT4 contributes to adipose tissue inflammation and atherosclerosis

Author keywords

Chemokines; Macrophages; peri aortic fat; T lymphocytes

Indexed keywords

APOENZYME; CD4 ANTIGEN; CD8 ANTIGEN; FRACTALKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUCOSE; INTERLEUKIN 12P40; LIPID; RANTES; STAT4 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; APOLIPOPROTEIN E; CHEMOKINE; CYTOKINE; STAT4 PROTEIN, MOUSE;

EID: 84944579505     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-15-0098     Document Type: Article
Times cited : (24)

References (53)
  • 1
    • 19044393872 scopus 로고    scopus 로고
    • Adipose tissue, inflammation, and cardiovascular disease
    • Berg AH & Scherer PE 2005 Adipose tissue, inflammation, and cardiovascular disease. Circulation Research 96 939-949. (doi:10.1161/01.RES. 0000163635.62927.34)
    • (2005) Circulation Research , vol.96 , pp. 939-949
    • Berg, A.H.1    Scherer, P.E.2
  • 4
    • 67651097885 scopus 로고    scopus 로고
    • Impaired development of human Th1 cells in patients with deficient expression of STAT4
    • Chang HC, Han L, Goswami R, Nguyen ET, Pelloso D, Robertson MJ & Kaplan MH 2009 Impaired development of human Th1 cells in patients with deficient expression of STAT4. Blood 113 5887-5890. (doi:10.1182/blood-2008-09-179820)
    • (2009) Blood , vol.113 , pp. 5887-5890
    • Chang, H.C.1    Han, L.2    Goswami, R.3    Nguyen, E.T.4    Pelloso, D.5    Robertson, M.J.6    Kaplan, M.H.7
  • 5
    • 77149139835 scopus 로고    scopus 로고
    • Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice
    • Cole BK, Keller SR, Wu R, Carter JD, Nadler JL & Nunemaker CS 2010 Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice. Hypertension 55 715-721. (doi:10.1161/HYPERTENSIONAHA.109. 148049)
    • (2010) Hypertension , vol.55 , pp. 715-721
    • Cole, B.K.1    Keller, S.R.2    Wu, R.3    Carter, J.D.4    Nadler, J.L.5    Nunemaker, C.S.6
  • 6
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • Darnell JE Jr 1997 STATs and gene regulation. Science 277 1630-1635. (doi:10.1126/science.277.5332.1630)
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell, J.E.1
  • 7
    • 0042926424 scopus 로고    scopus 로고
    • The role of interleukin-4 and interleukin- 12 in the progression of atherosclerosis in apolipoprotein E-deficient mice
    • Davenport P & Tipping PG 2003 The role of interleukin-4 and interleukin- 12 in the progression of atherosclerosis in apolipoprotein E-deficient mice. American Journal of Pathology 163 1117-1125. (doi:10.1016/S0002-9440(10)63471-2)
    • (2003) American Journal of Pathology , vol.163 , pp. 1117-1125
    • Davenport, P.1    Tipping, P.G.2
  • 10
    • 64549126102 scopus 로고    scopus 로고
    • Interleukin-17 and interferon-g are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells
    • Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS & Tellides G 2009 Interleukin-17 and interferon-g are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation 119 1424-1432. (doi:10.1161/CIRCULATIONAHA.108.827618)
    • (2009) Circulation , vol.119 , pp. 1424-1432
    • Eid, R.E.1    Rao, D.A.2    Zhou, J.3    Lo, S.F.4    Ranjbaran, H.5    Gallo, A.6    Sokol, S.I.7    Pfau, S.8    Pober, J.S.9    Tellides, G.10
  • 13
    • 56149116560 scopus 로고    scopus 로고
    • Requirements for CD8 T-cell migration into the human arterial wall
    • Gewaltig J, Kummer M, Koella C, Cathomas G & Biedermann BC 2008 Requirements for CD8 T-cell migration into the human arterial wall. Human Pathology 39 1756-1762. (doi:10.1016/j.humpath.2008.04.018)
    • (2008) Human Pathology , vol.39 , pp. 1756-1762
    • Gewaltig, J.1    Kummer, M.2    Koella, C.3    Cathomas, G.4    Biedermann, B.C.5
  • 16
    • 38449108309 scopus 로고    scopus 로고
    • Defective lipid delivery modulates glucose tolerance and metabolic response to diet in apolipoprotein E-deficient mice
    • Hofmann SM, Perez-Tilve D, Greer TM, Coburn BA, Grant E, Basford JE, Tschop MH & Hui DY 2008 Defective lipid delivery modulates glucose tolerance and metabolic response to diet in apolipoprotein E-deficient mice. Diabetes 57 5-12. (doi:10.2337/db07-0403)
    • (2008) Diabetes , vol.57 , pp. 5-12
    • Hofmann, S.M.1    Perez-Tilve, D.2    Greer, T.M.3    Coburn, B.A.4    Grant, E.5    Basford, J.E.6    Tschop, M.H.7    Hui, D.Y.8
  • 17
    • 0030962017 scopus 로고    scopus 로고
    • The state of the STATs: recent developments in the study of signal transduction to the nucleus
    • Horvath CM & Darnell JE 1997 The state of the STATs: recent developments in the study of signal transduction to the nucleus. Current Opinion in Cell Biology 9 233-239. (doi:10.1016/S0955-0674(97)80067-1)
    • (1997) Current Opinion in Cell Biology , vol.9 , pp. 233-239
    • Horvath, C.M.1    Darnell, J.E.2
  • 18
    • 33845535487 scopus 로고    scopus 로고
    • Endogenous ApoE expression modulates adipocyte triglyceride content and turnover
    • Huang ZH, Reardon CA & Mazzone T 2006 Endogenous ApoE expression modulates adipocyte triglyceride content and turnover. Diabetes 55 3394-3402. (doi:10.2337/db06-0354)
    • (2006) Diabetes , vol.55 , pp. 3394-3402
    • Huang, Z.H.1    Reardon, C.A.2    Mazzone, T.3
  • 19
    • 84871234634 scopus 로고    scopus 로고
    • ApoE derived from adipose tissue does not suppress atherosclerosis or correct hyperlipidemia in apoE knockout mice
    • Huang ZH, Reardon CA, Subbaiah PV, Getz GS & Mazzone T 2013 ApoE derived from adipose tissue does not suppress atherosclerosis or correct hyperlipidemia in apoE knockout mice. Journal of Lipid Research 54 202-213. (doi:10.1194/jlr. M031906)
    • (2013) Journal of Lipid Research , vol.54 , pp. 202-213
    • Huang, Z.H.1    Reardon, C.A.2    Subbaiah, P.V.3    Getz, G.S.4    Mazzone, T.5
  • 20
    • 0034023759 scopus 로고    scopus 로고
    • The Jak-STAT pathway
    • Imada K & Leonard WJ 2000 The Jak-STAT pathway. Molecular Immunology 37 1-11. (doi:10.1016/S0161-5890(00)00018-3)
    • (2000) Molecular Immunology , vol.37 , pp. 1-11
    • Imada, K.1    Leonard, W.J.2
  • 21
    • 18244392419 scopus 로고    scopus 로고
    • STAT4: a critical regulator of inflammation in vivo
    • Kaplan MH 2005 STAT4: a critical regulator of inflammation in vivo. Immunologic Research 31 231-242. (doi:10.1385/IR:31:3:231)
    • (2005) Immunologic Research , vol.31 , pp. 231-242
    • Kaplan, M.H.1
  • 22
    • 67349280145 scopus 로고    scopus 로고
    • Apolipoprotein E deficiency abrogates insulin resistance in a mouse model of type 2 diabetes mellitus
    • Kawashima Y, Chen J, Sun H, Lann D, Hajjar RJ, Yakar S & Leroith D 2009 Apolipoprotein E deficiency abrogates insulin resistance in a mouse model of type 2 diabetes mellitus. Diabetologia 52 1434-1441. (doi:10.1007/s00125-009-1378-8)
    • (2009) Diabetologia , vol.52 , pp. 1434-1441
    • Kawashima, Y.1    Chen, J.2    Sun, H.3    Lann, D.4    Hajjar, R.J.5    Yakar, S.6    Leroith, D.7
  • 23
    • 32044436977 scopus 로고    scopus 로고
    • STAT4/6-dependent differential regulation of chemokine receptors
    • Kim SH, Gunst KV & Sarvetnick N 2006 STAT4/6-dependent differential regulation of chemokine receptors. Clinical Immunology 118 250-257. (doi:10.1016/j.clim.2003.10.002)
    • (2006) Clinical Immunology , vol.118 , pp. 250-257
    • Kim, S.H.1    Gunst, K.V.2    Sarvetnick, N.3
  • 26
    • 77950020397 scopus 로고    scopus 로고
    • Association of pericardial fat accumulation rather than abdominal obesity with coronary atherosclerotic plaque formation in patients with suspected coronary artery disease
    • Konishi M, Sugiyama S, Sugamura K, Nozaki T, Ohba K, Matsubara J, Matsuzawa Y, Sumida H, Nagayoshi Y, Nakaura T, et al. 2010b Association of pericardial fat accumulation rather than abdominal obesity with coronary atherosclerotic plaque formation in patients with suspected coronary artery disease. Atherosclerosis 209 573-578. (doi:10.1016/j.atherosclerosis.2009.10.008)
    • (2010) Atherosclerosis , vol.209 , pp. 573-578
    • Konishi, M.1    Sugiyama, S.2    Sugamura, K.3    Nozaki, T.4    Ohba, K.5    Matsubara, J.6    Matsuzawa, Y.7    Sumida, H.8    Nagayoshi, Y.9    Nakaura, T.10
  • 28
    • 84874650489 scopus 로고    scopus 로고
    • Cytotoxic and proinflammatory CD8CT lymphocytes promote development of vulnerable atherosclerotic plaques in apoE-deficient mice
    • Kyaw T, Winship A, Tay C, Kanellakis P, Hosseini H, Cao A, Li P, Tipping P, Bobik A & Toh BH 2013 Cytotoxic and proinflammatory CD8CT lymphocytes promote development of vulnerable atherosclerotic plaques in apoE-deficient mice. Circulation 127 1028-1039. (doi:10.1161/CIRCULATIONAHA.112.001347)
    • (2013) Circulation , vol.127 , pp. 1028-1039
    • Kyaw, T.1    Winship, A.2    Tay, C.3    Kanellakis, P.4    Hosseini, H.5    Cao, A.6    Li, P.7    Tipping, P.8    Bobik, A.9    Toh, B.H.10
  • 29
    • 0036558732 scopus 로고    scopus 로고
    • Abdominal obesity is associated with increased risk of acute coronary events in men
    • Lakka HM, Lakka TA, Tuomilehto J & Salonen JT 2002 Abdominal obesity is associated with increased risk of acute coronary events in men. European Heart Journal 23 706-713. (doi:10.1053/euhj.2001.2889)
    • (2002) European Heart Journal , vol.23 , pp. 706-713
    • Lakka, H.M.1    Lakka, T.A.2    Tuomilehto, J.3    Salonen, J.T.4
  • 33
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • Lumeng CN, Bodzin JL & Saltiel AR 2007a Obesity induces a phenotypic switch in adipose tissue macrophage polarization. Journal of Clinical Investigation 117 175-184. (doi:10.1172/JCI29881)
    • (2007) Journal of Clinical Investigation , vol.117 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 34
    • 33847073149 scopus 로고    scopus 로고
    • Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity
    • Lumeng CN, Deyoung SM, Bodzin JL & Saltiel AR 2007b Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity. Diabetes 56 16-23. (doi:10.2337/db06-1076)
    • (2007) Diabetes , vol.56 , pp. 16-23
    • Lumeng, C.N.1    Deyoung, S.M.2    Bodzin, J.L.3    Saltiel, A.R.4
  • 36
    • 43849095463 scopus 로고    scopus 로고
    • Cardiovascular disease risk in type 2 diabetes mellitus: insights from mechanistic studies
    • Mazzone T, Chait A & Plutzky J 2008 Cardiovascular disease risk in type 2 diabetes mellitus: insights from mechanistic studies. Lancet 371 1800-1809. (doi:10.1016/S0140-6736(08)60768-0)
    • (2008) Lancet , vol.371 , pp. 1800-1809
    • Mazzone, T.1    Chait, A.2    Plutzky, J.3
  • 38
    • 39549118715 scopus 로고    scopus 로고
    • Visceral adipose tissue inflammation accelerates atherosclerosis in apolipoprotein E-deficient mice
    • Ohman MK, Shen Y, Obimba CI, Wright AP, Warnock M, Lawrence DA & Eitzman DT 2008 Visceral adipose tissue inflammation accelerates atherosclerosis in apolipoprotein E-deficient mice. Circulation 117 798-805. (doi:10.1161/CIRCULATIONAHA.107.717595)
    • (2008) Circulation , vol.117 , pp. 798-805
    • Ohman, M.K.1    Shen, Y.2    Obimba, C.I.3    Wright, A.P.4    Warnock, M.5    Lawrence, D.A.6    Eitzman, D.T.7
  • 39
    • 80055004075 scopus 로고    scopus 로고
    • Perivascular visceral adipose tissue induces atherosclerosis in apolipoprotein E deficient mice
    • Ohman MK, Luo W, Wang H, Guo C, AbdallahW, RussoHM & Eitzman DT 2011 Perivascular visceral adipose tissue induces atherosclerosis in apolipoprotein E deficient mice. Atherosclerosis 219 33-39. (doi:10.1016/j.atherosclerosis.2011.07.012)
    • (2011) Atherosclerosis , vol.219 , pp. 33-39
    • Ohman, M.K.1    Luo, W.2    Wang, H.3    Guo, C.4    Abdallah, W.5    Russo, H.M.6    Eitzman, D.T.7
  • 40
    • 78149358733 scopus 로고    scopus 로고
    • The role of epicardial and perivascular adipose tissue in the pathophysiology of cardiovascular disease
    • Ouwens DM, Sell H, Greulich S & Eckel J 2010 The role of epicardial and perivascular adipose tissue in the pathophysiology of cardiovascular disease. Journal of Cellular and Molecular Medicine 14 2223-2234. (doi:10.1111/j.1582-4934.2010.01141.x)
    • (2010) Journal of Cellular and Molecular Medicine , vol.14 , pp. 2223-2234
    • Ouwens, D.M.1    Sell, H.2    Greulich, S.3    Eckel, J.4
  • 41
    • 33644875634 scopus 로고    scopus 로고
    • Activation of the 12-lipoxygenase. signal transducer. activator of transcription pathway during neointima formation in a model of the metabolic syndrome.
    • Pei H, Gu J, Thimmalapura PR, Mison A & Nadler JL 2006 Activation of the 12-lipoxygenase and signal transducer and activator of transcription pathway during neointima formation in a model of the metabolic syndrome. American Journal of Physiology. Endocrinology and Metabolism 290 E92-E102. (doi:10.1152/ajpendo.00133.2005)
    • (2006) American Journal of Physiology. Endocrinology. Metabolism 290 E92-E102.
    • Pei, H.1    Gu, J.2    Thimmalapura, P.R.3    Mison, A.4    Nadler, J.L.5
  • 42
    • 0026725757 scopus 로고
    • Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
    • Plump AS, Smith JD, Hayek T, Aalto-Setala K, Walsh A, Verstuyft JG, Rubin EM & Breslow JL 1992 Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell 71 343-353. (doi:10.1016/0092-8674(92) 90362-G)
    • (1992) Cell , vol.71 , pp. 343-353
    • Plump, A.S.1    Smith, J.D.2    Hayek, T.3    Aalto-Setala, K.4    Walsh, A.5    Verstuyft, J.G.6    Rubin, E.M.7    Breslow, J.L.8
  • 43
    • 70349578367 scopus 로고    scopus 로고
    • Obesity promotes inflammation in periaortic adipose tissue and angiotensin II-induced abdominal aortic aneurysm formation
    • Police SB, Thatcher SE, Charnigo R, Daugherty A & Cassis LA 2009 Obesity promotes inflammation in periaortic adipose tissue and angiotensin II-induced abdominal aortic aneurysm formation. Arteriosclerosis, Thrombosis, and Vascular Biology 29 1458-1464. (doi:10.1161/ATVBAHA.109.192658)
    • (2009) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.29 , pp. 1458-1464
    • Police, S.B.1    Thatcher, S.E.2    Charnigo, R.3    Daugherty, A.4    Cassis, L.A.5
  • 46
    • 0028862192 scopus 로고    scopus 로고
    • PalinskiW1995 Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in L.D.L receptor-deficient and apolipoprotein E-deficient mice
    • Tangirala RK, Rubin EM & PalinskiW1995 Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice. Journal of Lipid Research 36 2320-2328.
    • Journal of Lipid Research , vol.36 , pp. 2320-2328
    • Tangirala, R.K.1    Rubin, E.M.2
  • 49
    • 0036784641 scopus 로고    scopus 로고
    • IL-12 provides proliferation and survival signals to murine CD4C T cells through phosphatidylinositol 3-kinase/Akt signaling pathway
    • Yoo JK, Cho JH, Lee SW & Sung YC 2002 IL-12 provides proliferation and survival signals to murine CD4C T cells through phosphatidylinositol 3-kinase/Akt signaling pathway. Journal of Immunology 169 3637-3643. (doi:10.4049/jimmunol.169.7.3637)
    • (2002) Journal of Immunology , vol.169 , pp. 3637-3643
    • Yoo, J.K.1    Cho, J.H.2    Lee, S.W.3    Sung, Y.C.4
  • 50
    • 19744362790 scopus 로고    scopus 로고
    • "Vasocrine" signalling from perivascular fat: a mechanism linking insulin resistance to vascular disease
    • Yudkin JS, Eringa E & Stehouwer CD 2005 "Vasocrine" signalling from perivascular fat: a mechanism linking insulin resistance to vascular disease. Lancet 365 1817-1820. (doi:10.1016/S0140-6736(05)66585-3)
    • (2005) Lancet , vol.365 , pp. 1817-1820
    • Yudkin, J.S.1    Eringa, E.2    Stehouwer, C.D.3
  • 51
    • 34548354722 scopus 로고    scopus 로고
    • Human adipose tissue macrophages are of an antiinflammatory phenotype but capable of excessive pro-inflammatory mediator production
    • Zeyda M, Farmer D, Todoric J, Aszmann O, Speiser M, Gyori G, Zlabinger GJ & Stulnig TM 2007 Human adipose tissue macrophages are of an antiinflammatory phenotype but capable of excessive pro-inflammatory mediator production. International Journal of Obesity 31 1420-1428. (doi:10.1038/sj.ijo.0803632)
    • (2007) International Journal of Obesity , vol.31 , pp. 1420-1428
    • Zeyda, M.1    Farmer, D.2    Todoric, J.3    Aszmann, O.4    Speiser, M.5    Gyori, G.6    Zlabinger, G.J.7    Stulnig, T.M.8
  • 53
    • 0037144594 scopus 로고    scopus 로고
    • Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemia
    • Zhao L, CuffCA, Moss E, Wille U, Cyrus T, Klein EA, Pratico D, Rader DJ, Hunter CA, Pure E, et al. 2002 Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemia. Journal of Biological Chemistry 277 35350-35356. (doi:10.1074/jbc. M205738200)
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 35350-35356
    • Zhao, L.1    Cuff, C.A.2    Moss, E.3    Wille, U.4    Cyrus, T.5    Klein, E.A.6    Pratico, D.7    Rader, D.J.8    Hunter, C.A.9    Pure, E.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.