메뉴 건너뛰기




Volumn 13, Issue 4, 2010, Pages 371-376

Adipose tissue remodeling in pathophysiology of obesity

Author keywords

adipose tissue; extracellular matrix; inflammation; obesity; remodeling

Indexed keywords

INSULIN;

EID: 77954349282     PISSN: 13631950     EISSN: 14736519     Source Type: Journal    
DOI: 10.1097/MCO.0b013e32833aabef     Document Type: Review
Times cited : (165)

References (59)
  • 1
    • 0016292538 scopus 로고
    • Postnatal development of adipocyte cellularity in the normal rat
    • Greenwood MR, Hirsch J. Postnatal development of adipocyte cellularity in the normal rat. J Lipid Res 1974; 15:474-483.
    • (1974) J Lipid Res , vol.15 , pp. 474-483
    • Greenwood, M.R.1    Hirsch, J.2
  • 3
    • 27444437321 scopus 로고    scopus 로고
    • Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
    • Cinti S, Mitchell G, Barbatelli G, et al. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 2005; 46:2347-2355.
    • (2005) J Lipid Res , vol.46 , pp. 2347-2355
    • Cinti, S.1    Mitchell, G.2    Barbatelli, G.3
  • 4
    • 36849012057 scopus 로고    scopus 로고
    • Adipocyte death, adipose tissue remodeling, and obesity complications
    • Strissel KJ, Stancheva Z, Miyoshi H, et al. Adipocyte death, adipose tissue remodeling, and obesity complications. Diabetes 2007; 56:2910-2918.
    • (2007) Diabetes , vol.56 , pp. 2910-2918
    • Strissel, K.J.1    Stancheva, Z.2    Miyoshi, H.3
  • 5
    • 38849118568 scopus 로고    scopus 로고
    • In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue.
    • Nishimura S, Manabe I, Nagasaki M, et al. In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue. J Clin Invest 2008; 118:710-721.
    • (2008) J Clin Invest , vol.118 , pp. 710-721
    • Nishimura, S.1    Manabe, I.2    Nagasaki, M.3
  • 6
    • 0031831765 scopus 로고    scopus 로고
    • Qualitative regional differ ences in adipose tissue growth and cellularity in male Wistar rats fed ad libitum
    • DiGirolamo M, Fine JB, Tagra K, Rossmanith R. Qualitative regional differ ences in adipose tissue growth and cellularity in male Wistar rats fed ad libitum. Am J Physiol 1998; 274:R1460-R1467.
    • (1998) Am J Physiol , vol.274
    • Digirolamo, M.1    Fine, J.B.2    Tagra, K.3    Rossmanith, R.4
  • 7
    • 77953611520 scopus 로고    scopus 로고
    • A microarray analysis of sexual dimorphism of adipose tissues in high-fat-diet-induced obese mice
    • [Epub ahead of print]
    • Grove KL, Fried SK, Greenberg AS, et al. A microarray analysis of sexual dimorphism of adipose tissues in high-fat-diet-induced obese mice. Int JObes (Lond) 2010. [Epub ahead of print]
    • (2010) Int JObes (Lond)
    • Grove, K.L.1    Fried, S.K.2    Greenberg, A.S.3
  • 8
    • 34347249246 scopus 로고    scopus 로고
    • Macrophage infiltration into omental versus subcutaneous fat across different populations: Effect of regional adiposity and the comorbidities of obesity
    • Harman-Boehm I, Bluher M, Redel H, et al. Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesity. J Clin Endocrinol Metab 2007; 92:2240-2247.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 2240-2247
    • Harman-Boehm, I.1    Bluher, M.2    Redel, H.3
  • 10
    • 44849132591 scopus 로고    scopus 로고
    • Dynamics of fat cell turnover in humans
    • Spalding KL, Arner E, Westermark PO, et al. Dynamics of fat cell turnover in humans. Nature 2008; 453:783-787.
    • (2008) Nature , vol.453 , pp. 783-787
    • Spalding, K.L.1    Arner, E.2    Westermark, P.O.3
  • 11
    • 0348230958 scopus 로고    scopus 로고
    • Obesity is associated with macrophage accumulation in adipose tissue
    • Weisberg SP, McCann D, Desai M, et al. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003; 112:1796-1808.
    • (2003) J Clin Invest , vol.112 , pp. 1796-1808
    • Weisberg, S.P.1    McCann, D.2    Desai, M.3
  • 12
    • 77449092780 scopus 로고    scopus 로고
    • Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: Dissociation of adipocyte hypertrophy from inflammation
    • Yeop HC, Kargi AY, Omer M, et al. Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation. Diabetes 2010; 59:386-396.
    • Diabetes , vol.2010 , Issue.59 , pp. 386-396
    • Yeop, H.C.1    Kargi, A.Y.2    Omer, M.3
  • 13
    • 34249812073 scopus 로고    scopus 로고
    • Prevention of high-fat diet-induced adipose tissue remodeling in obese diabetic mice by n-3 polyunsaturated fatty acids
    • Huber J, Loffler M, Bilban M, et al. Prevention of high-fat diet-induced adipose tissue remodeling in obese diabetic mice by n-3 polyunsaturated fatty acids. Int J Obes (Lond) 2007; 31:1004-1013.
    • (2007) Int J Obes (Lond) , vol.31 , pp. 1004-1013
    • Huber, J.1    Loffler, M.2    Bilban, M.3
  • 14
    • 33746772121 scopus 로고    scopus 로고
    • Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids
    • Todoric J, Loffler M, Huber J, et al. Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids. Diabetologia 2006; 49:2109-2119.
    • (2006) Diabetologia , vol.49 , pp. 2109-2119
    • Todoric, J.1    Loffler, M.2    Huber, J.3
  • 15
    • 62849107819 scopus 로고    scopus 로고
    • Metabolic dysregulation and adipose tissue fibrosis: Role of collagen VI
    • KhanT, Muise ES, Iyengar P, et al. Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI. Mol Cell Biol 2009; 29:1575-1591.
    • (2009) Mol Cell Biol , vol.29 , pp. 1575-1591
    • Khant Muise, E.S.1    Iyengar, P.2
  • 16
    • 0033853610 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor 1, transforming growth factor-beta1, and BMI are closely associated in human adipose tissue during morbid obesity
    • Alessi MC, Bastelica D, Morange P, et al. Plasminogen activator inhibitor 1, transforming growth factor-beta1, and BMI are closely associated in human adipose tissue during morbid obesity. Diabetes 2000; 49:1374-1380.
    • (2000) Diabetes , vol.49 , pp. 1374-1380
    • Alessi, M.C.1    Bastelica, D.2    Morange, P.3
  • 17
    • 0038823617 scopus 로고    scopus 로고
    • Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation
    • Chavey C, Mari B, Monthouel MN, et al. Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation. J Biol Chem 2003; 278:11888-11896.
    • (2003) J Biol Chem , vol.278 , pp. 11888-11896
    • Chavey, C.1    Mari, B.2    Monthouel, M.N.3
  • 18
    • 0036227213 scopus 로고    scopus 로고
    • Modulation of adipose tissue expression of murine matrix metalloproteinases and their tissue inhibitors with obesity
    • Maquoi E, Munaut C, Colige A, et al. Modulation of adipose tissue expression of murine matrix metalloproteinases and their tissue inhibitors with obesity. Diabetes 2002; 51:1093-1101.
    • (2002) Diabetes , vol.51 , pp. 1093-1101
    • Maquoi, E.1    Munaut, C.2    Colige, A.3
  • 19
    • 45749117243 scopus 로고    scopus 로고
    • A functional role of gelatinase A in the development of nutritionally induced obesity in mice
    • Van HM, Lijnen HR. A functional role of gelatinase A in the development of nutritionally induced obesity in mice. J Thromb Haemost 2008; 6:1198-1206.
    • (2008) J Thromb Haemost , vol.6 , pp. 1198-1206
    • Van, H.M.1    Lijnen, H.R.2
  • 20
    • 33751535467 scopus 로고    scopus 로고
    • Cathepsin K in adipocyte differentiation and its potential role in the pathogenesis of obesity
    • Xiao Y, Junfeng H, Tianhong L, et al. Cathepsin K in adipocyte differentiation and its potential role in the pathogenesis of obesity. J Clin Endocrinol Metab 2006; 91:4520-4527.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 4520-4527
    • Xiao, Y.1    Junfeng, H.2    Tianhong, L.3
  • 21
    • 77951630662 scopus 로고    scopus 로고
    • Cathepsins in human obesity: Changes in energy balance predominantly affect cathepsin S in adipose tissue and in circulation
    • Naour N, Rouault C, Fellahi S, et al. Cathepsins in human obesity: changes in energy balance predominantly affect cathepsin S in adipose tissue and in circulation. J Clin Endocrinol Metab 2010; 95:1861-1868.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 1861-1868
    • Naour, N.1    Rouault, C.2    Fellahi, S.3
  • 22
    • 33644817971 scopus 로고    scopus 로고
    • Weight loss reduces adipose tissue cathepsin S and its circulating levels in morbidly obese women
    • Taleb S, Cancello R, Poitou C, et al. Weight loss reduces adipose tissue cathepsin S and its circulating levels in morbidly obese women. J Clin Endocrinol Metab 2006; 91:1042-1047.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1042-1047
    • Taleb, S.1    Cancello, R.2    Poitou, C.3
  • 23
    • 57549118164 scopus 로고    scopus 로고
    • Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice
    • Yang M, Sun J, Zhang T, et al. Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice. Arterioscler Thromb Vasc Biol 2008; 28:2202-2208.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 2202-2208
    • Yang, M.1    Sun, J.2    Zhang, T.3
  • 24
    • 40149111859 scopus 로고    scopus 로고
    • Cathepsin K null mice show reduced adiposity during the rapid accumulation of fat stores
    • Funicello M, Novelli M, Ragni M, et al. Cathepsin K null mice show reduced adiposity during the rapid accumulation of fat stores. PLoS One 2007; 2:e683.
    • (2007) PLoS One , vol.2
    • Funicello, M.1    Novelli, M.2    Ragni, M.3
  • 25
    • 34547564529 scopus 로고    scopus 로고
    • Cathepsin L activity controls adipogenesis and glucose tolerance
    • Yang M, Zhang Y, Pan J, et al. Cathepsin L activity controls adipogenesis and glucose tolerance. Nat Cell Biol 2007; 9:970-977.
    • (2007) Nat Cell Biol , vol.9 , pp. 970-977
    • Yang, M.1    Zhang, Y.2    Pan, J.3
  • 26
    • 0036094812 scopus 로고    scopus 로고
    • ADAM 12 protease induces adipogenesis in transgenic mice
    • Kawaguchi N, Xu X, TajimaR, et al. ADAM 12 protease induces adipogenesis in transgenic mice. Am J Pathol 2002; 160:1895-1903.
    • (2002) Am J Pathol , vol.160 , pp. 1895-1903
    • Kawaguchi, N.1    Tajimar, X.X.2
  • 27
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 2007; 117:175-184.
    • (2007) J Clin Invest , vol.117 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 28
    • 70350560546 scopus 로고    scopus 로고
    • Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice
    • Fujisaka S, Usui I, Bukhari A, et al. Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice. Diabetes 2009; 58:2574-2582.
    • (2009) Diabetes , vol.58 , pp. 2574-2582
    • Fujisaka, S.1    Usui, I.2    Bukhari, A.3
  • 29
    • 34548354722 scopus 로고    scopus 로고
    • Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production
    • Zeyda M, Farmer D, Todoric J, et al. Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production. Int J Obes (Lond) 2007; 31:1420-1428.
    • (2007) Int J Obes (Lond) , vol.31 , pp. 1420-1428
    • Zeyda, M.1    Farmer, D.2    Todoric, J.3
  • 30
    • 39549122799 scopus 로고    scopus 로고
    • Remodeling phenotype of human subcutaneous adipose tissue macrophages
    • Bourlier V, Zakaroff-Girard A, Miranville A, et al. Remodeling phenotype of human subcutaneous adipose tissue macrophages. Circulation 2008; 117:806-815.
    • (2008) Circulation , vol.117 , pp. 806-815
    • Bourlier, V.1    Zakaroff-Girard, A.2    Miranville, A.3
  • 31
    • 77951822653 scopus 로고    scopus 로고
    • Dynamic, M2-like remodeling phe-notypesof CD11c+adipose tissue macrophages during high fat diet-induced obesity in mice.
    • Shaul ME, Bennett G, Strissel KJ, et al. Dynamic, M2-like remodeling phe-notypesof CD11c+adipose tissue macrophages during high fat diet-induced obesity in mice. Diabetes 2010; 59:1171-1181.
    • (2010) Diabetes , vol.59 , pp. 1171-1181
    • Shaul, M.E.1    Bennett, G.2    Strissel, K.J.3
  • 33
    • 68349150756 scopus 로고    scopus 로고
    • CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
    • Nishimura S, Manabe I, Nagasaki M, et al. CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 2009; 15:914-920.
    • (2009) Nat Med , vol.15 , pp. 914-920
    • Nishimura, S.1    Manabe, I.2    Nagasaki, M.3
  • 34
    • 68349148211 scopus 로고    scopus 로고
    • Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters.
    • Feuerer M, HerreroL, CipollettaD, et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 2009; 15:930-939.
    • (2009) Nat Med , vol.15 , pp. 930-939
    • Feuerer, M.1    Herrero, L.2    Cipolletta, D.3
  • 35
    • 68349137821 scopus 로고    scopus 로고
    • Normalization of obesity-associated insulin resistance through immunotherapy
    • Winer S, Chan Y, Paltser G, et al. Normalization of obesity-associated insulin resistance through immunotherapy. Nat Med 2009; 15:921-929.
    • (2009) Nat Med , vol.15 , pp. 921-929
    • Winer, S.1    Chan, Y.2    Paltser, G.3
  • 36
    • 68349160704 scopus 로고    scopus 로고
    • Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
    • Liu J, Divoux A, Sun J, et al. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med 2009; 15:940-945.
    • (2009) Nat Med , vol.15 , pp. 940-945
    • Liu, J.1    Divoux, A.2    Sun, J.3
  • 37
    • 34249719581 scopus 로고    scopus 로고
    • Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels
    • Nishimura S, Manabe I, Nagasaki M, et al. Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels. Diabetes 2007; 56:1517-1526.
    • (2007) Diabetes , vol.56 , pp. 1517-1526
    • Nishimura, S.1    Manabe, I.2    Nagasaki, M.3
  • 38
    • 0021260731 scopus 로고
    • Adipocyte blood flow: Influence of age, anatomic location, and dietary manipulation
    • Crandall DL, Goldstein BM, Huggins F, Cervoni P. Adipocyte blood flow: influence of age, anatomic location, and dietary manipulation. Am J Physiol 1984; 247:R46-R51.
    • (1984) Am J Physiol , vol.247
    • Crandall, D.L.1    Goldstein, B.M.2    Huggins, F.3    Cervoni, P.4
  • 39
    • 0026708859 scopus 로고
    • Glycerol production in subcutaneous adipose tissue in lean and obese humans
    • Jansson PA, Larsson A, Smith U, Lonnroth P. Glycerol production in subcutaneous adipose tissue in lean and obese humans. J Clin Invest 1992; 89:1610-1617.
    • (1992) J Clin Invest , vol.89 , pp. 1610-1617
    • Jansson, P.A.1    Larsson, A.2    Smith, U.3    Lonnroth, P.4
  • 40
    • 62749167010 scopus 로고    scopus 로고
    • Reduced adipose tissue oxygenation in human obesity: Evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response
    • Pasarica M, Sereda OR, Redman LM, et al. Reduced adipose tissue oxygenation in human obesity: evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response. Diabetes 2009; 58:71 8-725.
    • (2009) Diabetes , vol.58 , Issue.71 , pp. 8-725
    • Pasarica, M.1    Sereda, O.R.2    Redman, L.M.3
  • 41
    • 70349484670 scopus 로고    scopus 로고
    • Mechanisms of obesity and related pathologies: The macro-and microcirculation of adipose tissue
    • Rutkowski JM, Davis KE, Scherer PE. Mechanisms of obesity and related pathologies: the macro-and microcirculation of adipose tissue. FEBS J 2009; 276:5738-5746.
    • (2009) FEBS J , vol.276 , pp. 5738-5746
    • Rutkowski, J.M.1    Davis, K.E.2    Scherer, P.E.3
  • 42
    • 0036678477 scopus 로고    scopus 로고
    • Adipose tissue mass can be regulated through the vasculature
    • Rupnick MA, Panigrahy D, Zhang CY, et al. Adipose tissue mass can be regulated through the vasculature. Proc Natl Acad Sci USA 2002; 99:10730-10735.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10730-10735
    • Rupnick, M.A.1    Panigrahy, D.2    Zhang, C.Y.3
  • 43
    • 3042786130 scopus 로고    scopus 로고
    • Angiogenesis inhibitor, TNP-470, prevents diet-induced and genetic obesity in mice
    • Brakenhielm E, Cao R, Gao B, et al. Angiogenesis inhibitor, TNP-470, prevents diet-induced and genetic obesity in mice. Circ Res 2004; 94:1579-1588.
    • (2004) Circ Res , vol.94 , pp. 1579-1588
    • Brakenhielm, E.1    Cao, R.2    Gao, B.3
  • 44
    • 0032508682 scopus 로고    scopus 로고
    • Biological action of leptin as an angiogenic factor
    • Sierra-Honigmann MR, Nath AK, Murakami C, et al. Biological action of leptin as an angiogenic factor. Science 1998; 281:1683-1686.
    • (1998) Science , vol.281 , pp. 1683-1686
    • Sierra-Honigmann, M.R.1    Nath, A.K.2    Murakami, C.3
  • 45
    • 3142616447 scopus 로고    scopus 로고
    • Adiponectin stimulates angiogenesis in response to tissue ischemia through stimulation of AMP-activated protein kinase signaling
    • DOI 10.1074/jbc.M402558200
    • Shibata R, Ouchi N, Kihara S, et al. Adiponectin stimulates angiogenesis in response to tissue ischemia through stimulation of amp-activated protein kinase signaling. J Biol Chem 2004; 279:28670-28674. (Pubitemid 38900150)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.27 , pp. 28670-28674
    • Shibata, R.1    Ouchi, N.2    Kihara, S.3    Sato, K.4    Funahashi, T.5    Walsh, K.6
  • 46
    • 34548402222 scopus 로고    scopus 로고
    • Adipocyte-derived serum amyloid A3 and hyaluronan play a role in monocyte recruitment and adhesion
    • Han CY, Subramanian S, Chan CK, et al. Adipocyte-derived serum amyloid A3 and hyaluronan play a role in monocyte recruitment and adhesion. Diabetes 2007; 56:2260-2273.
    • (2007) Diabetes , vol.56 , pp. 2260-2273
    • Han, C.Y.1    Subramanian, S.2    Chan, C.K.3
  • 47
    • 0029100030 scopus 로고
    • A novel biologic function of serum amyloid A. Induction of T lymphocyte migration and adhesion
    • Xu L, Badolato R, Murphy WJ, etal.A novel biologic function of serum amyloid A. Induction of T lymphocyte migration and adhesion. J Immunol 1995; 155:1184-1190.
    • (1995) J Immunol , vol.155 , pp. 1184-1190
    • Xu, L.1    Badolato, R.2    Murphy, W.J.3
  • 48
    • 33745584354 scopus 로고    scopus 로고
    • Acute-phase serum amyloid A: An inflammatory adipokine and potential link between obesity and its metabolic complications
    • Yang RZ, Lee MJ, Hu H, et al. Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications. PLoS Med 2006; 3:e287.
    • (2006) PLoS Med , vol.3
    • Yang, R.Z.1    Lee, M.J.2    Hu, H.3
  • 49
    • 34247603540 scopus 로고    scopus 로고
    • Activated omentum becomes rich in factors that promote healing and tissue regeneration
    • Litbarg NO, Gudehithlu KP, Sethupathi P, et al. Activated omentum becomes rich in factors that promote healing and tissue regeneration. Cell Tissue Res 2007; 328:487-497.
    • (2007) Cell Tissue Res , vol.328 , pp. 487-497
    • Litbarg, N.O.1    Gudehithlu, K.P.2    Sethupathi, P.3
  • 50
    • 8244260081 scopus 로고    scopus 로고
    • Regional variation in adipose tissue insulin action and GLUT4 glucose transporter expression in severely obese premenopausal women
    • Marette A, Mauriege P, Marcotte B, et al. Regional variation in adipose tissue insulin action and GLUT4 glucose transporter expression in severely obese premenopausal women. Diabetologia 1997; 40:590-598.
    • (1997) Diabetologia , vol.40 , pp. 590-598
    • Marette, A.1    Mauriege, P.2    Marcotte, B.3
  • 51
    • 0028919571 scopus 로고
    • Regional variation in adipose tissue metabolism of severely obese premenopausal women
    • Mauriege P, Marette A, Atgie C, et al. Regional variation in adipose tissue metabolism of severely obese premenopausal women. J Lipid Res 1995; 36:672-684.
    • (1995) J Lipid Res , vol.36 , pp. 672-684
    • Mauriege, P.1    Marette, A.2    Atgie, C.3
  • 52
    • 33744932403 scopus 로고    scopus 로고
    • Identification of omentin as a novel depot-specific adipokine in human adipose tissue: Possible role in modulating insulin action
    • Yang RZ, Lee MJ, Hu H, et al. Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action. Am J Physiol Endocrinol Metab 2006; 290:E1253-E1261.
    • (2006) Am J Physiol Endocrinol Metab , vol.290
    • Yang, R.Z.1    Lee, M.J.2    Hu, H.3
  • 53
    • 0035430576 scopus 로고    scopus 로고
    • Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance
    • de Souza CJ, Eckhardt M, Gagen K, et al. Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance. Diabetes 2001; 50:1863-1871.
    • (2001) Diabetes , vol.50 , pp. 1863-1871
    • De Souza, C.J.1    Eckhardt, M.2    Gagen, K.3
  • 54
    • 57049122852 scopus 로고    scopus 로고
    • Enhanced angiogenesis in obesity and in response to PPARgamma activators through adipocyte VEGF and ANGPTL4 production
    • Gealekman O, Burkart A, Chouinard M, et al. Enhanced angiogenesis in obesity and in response to PPARgamma activators through adipocyte VEGF and ANGPTL4 production. Am J Physiol Endocrinol Metab 2008; 295: E1056-E1064.
    • (2008) Am J Physiol Endocrinol Metab , vol.295
    • Gealekman, O.1    Burkart, A.2    Chouinard, M.3
  • 55
    • 53049093989 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma activation promotes infiltration of alternatively activated macrophages into adipose tissue
    • Stienstra R, Duval C, Keshtkar S, et al. Peroxisome proliferator- activated receptor gamma activation promotes infiltration of alternatively activated macrophages into adipose tissue. J Biol Chem 2008; 283:22620-22627.
    • (2008) J Biol Chem , vol.283 , pp. 22620-22627
    • Stienstra, R.1    Duval, C.2    Keshtkar, S.3
  • 56
    • 33748314535 scopus 로고    scopus 로고
    • Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity
    • Cancello R, Tordjman J, Poitou C, et al. Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity. Diabetes 2006; 55:1554-1561.
    • (2006) Diabetes , vol.55 , pp. 1554-1561
    • Cancello, R.1    Tordjman, J.2    Poitou, C.3
  • 57
    • 23644450775 scopus 로고    scopus 로고
    • Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss
    • Cancello R, Henegar C, Viguerie N, et al. Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss. Diabetes 2005; 54:2277-2286.
    • (2005) Diabetes , vol.54 , pp. 2277-2286
    • Cancello, R.1    Henegar, C.2    Viguerie, N.3
  • 58
    • 51649088497 scopus 로고    scopus 로고
    • Adipose macrophage infiltration is associated with insulin resistance and vascular endothelial dysfunction in obese subjects
    • Apovian CM, Bigornia S, Mott M, et al. Adipose macrophage infiltration is associated with insulin resistance and vascular endothelial dysfunction in obese subjects. Arterioscler Thromb Vasc Biol 2008; 28:1654-1659.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1654-1659
    • Apovian, C.M.1    Bigornia, S.2    Mott, M.3
  • 59
    • 34547558619 scopus 로고    scopus 로고
    • Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity
    • Kolak M, Westerbacka J, Velagapudi VR, et al. Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity. Diabetes 2007; 56:1960-1968.
    • (2007) Diabetes , vol.56 , pp. 1960-1968
    • Kolak, M.1    Westerbacka, J.2    Velagapudi, V.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.