Disruption of rhodopsin dimerization with synthetic peptides targeting an interaction interface

Journal of Biological Chemistry

Volumn 290, Issue 42, 2015, Pages 25728-25744

  Jastrzebska, Beata ^a   Chen, Yuanyuan ^a   Orban, Tivadar ^a   Jin, Hui ^a   Hofmann, Lukas ^a   Palczewski, Krzysztof ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BINS; CROSSLINKING; DIMERIZATION; DISSOCIATION; ENERGY TRANSFER; FILTRATION; MASS SPECTROMETRY; MICROFILTRATION; MONOMERS; PEPTIDES; PROTEINS; STABILIZATION;

BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; CROSSLINKING REACTION; DISSOCIATION CONSTANT; G PROTEIN COUPLED RECEPTORS; INTERACTION INTERFACE; INTERACTIVE INTERFACES; PHYSICAL INTERACTIONS; SUPRAMOLECULAR ORGANIZATIONS;

DIMERS;

G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN GT; RHODOPSIN; SYNTHETIC PEPTIDE; TRANSMEMBRANE 1 PEPTIDE; TRANSMEMBRANE 2 PEPTIDE; TRANSMEMBRANE 4 PEPTIDE; TRANSMEMBRANE 5 PEPTIDE; UNCLASSIFIED DRUG; PEPTIDE;

ARTICLE; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIMERIZATION; GEL FILTRATION; IN VITRO STUDY; LABEL FREE ASSAY; MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN PROTEIN INTERACTION; RETINA ROD OUTER SEGMENT; THERMOSTABILITY; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; HEK293 CELL LINE; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE;

AMINO ACID SEQUENCE; ANIMALS; DIMERIZATION; GTP-BINDING PROTEINS; HEK293 CELLS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PEPTIDES; RHODOPSIN;

EID: 84944464034     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.662684     Document Type: Article

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