-
1
-
-
0018890003
-
Metabolism of proline and the hydroxyprolines
-
Adams, E., and Frank, L. (1980) Metabolism of proline and the hydroxyprolines. Annu. Rev. Biochem. 49, 1005-1061
-
(1980)
Annu. Rev.Biochem.
, vol.49
, pp. 1005-1061
-
-
Adams, E.1
Frank, L.2
-
2
-
-
0021994031
-
The regulatory functions of proline and pyrroline-5-carboxylic acid
-
Phang, J. M. (1985) The regulatory functions of proline and pyrroline-5-carboxylic acid. Curr. Top. Cell. Regul. 25, 91-132
-
(1985)
Curr. Top.Cell. Regul.
, vol.25
, pp. 91-132
-
-
Phang, J.M.1
-
3
-
-
0023735598
-
Stimulation of phosphoribosyl pyrophosphate and purine nucleotide production by pyrroline 5-carboxylate in human erythrocytes
-
Yeh, G. C., and Phang, J. M. (1988) Stimulation of phosphoribosyl pyrophosphate and purine nucleotide production by pyrroline 5-carboxylate in human erythrocytes. J. Biol. Chem. 263, 13083-13089
-
(1988)
J. Biol.Chem.
, vol.263
, pp. 13083-13089
-
-
Yeh, G.C.1
Phang, J.M.2
-
4
-
-
0035266127
-
Proline oxidase, encoded by p53-induced gene-6, catalyzes the generation of proline-dependent reactive oxygen species
-
Donald, S. P., Sun, X. Y., Hu, C. A., Yu, J., Mei, J. M., Valle, D., and Phang, J. M. (2001) Proline oxidase, encoded by p53-induced gene-6, catalyzes the generation of proline-dependent reactive oxygen species. Cancer Res. 61, 1810-1815
-
(2001)
Cancer Res
, vol.61
, pp. 1810-1815
-
-
Donald, S.P.1
Sun, X.Y.2
Hu, C.A.3
Yu, J.4
Mei, J.M.5
Valle, D.6
Phang, J.M.7
-
5
-
-
33644850483
-
Proline oxidase, a proapoptotic gene, is induced by troglitazone: Evidence for both peroxisome proliferator-activated receptor γ-dependent and -independent mechanisms
-
Pandhare, J., Cooper, S. K., and Phang, J. M. (2006) Proline oxidase, a proapoptotic gene, is induced by troglitazone: evidence for both peroxisome proliferator-activated receptor γ-dependent and -independent mechanisms. J. Biol. Chem. 281, 2044-2052
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 2044-2052
-
-
Pandhare, J.1
Cooper, S.K.2
Phang, J.M.3
-
6
-
-
84901316606
-
Cellular mechanisms and physiological consequences of redox-dependent signalling
-
Holmström, K. M., and Finkel, T. (2014) Cellular mechanisms and physiological consequences of redox-dependent signalling. Nat. Rev. Mol. Cell Biol. 15, 411-421
-
(2014)
Nat. Rev. Mol. Cell Biol.
, vol.15
, pp. 411-421
-
-
Holmström, K.M.1
Finkel, T.2
-
7
-
-
79960286223
-
Signal transduction by reactive oxygen species
-
Finkel, T. (2011) Signal transduction by reactive oxygen species. J. Cell Biol. 194, 7-15
-
(2011)
J. Cell Biol.
, vol.194
, pp. 7-15
-
-
Finkel, T.1
-
8
-
-
53849096017
-
The metabolism of proline, a stress substrate, modulates carcinogenic pathways
-
Phang, J. M., Donald, S. P., Pandhare, J., and Liu, Y. (2008) The metabolism of proline, a stress substrate, modulates carcinogenic pathways. Amino Acids 35, 681-690
-
(2008)
Amino Acids
, vol.35
, pp. 681-690
-
-
Phang, J.M.1
Donald, S.P.2
Pandhare, J.3
Liu, Y.4
-
9
-
-
84871196795
-
The proline regulatory axis and cancer
-
Phang, J. M., Liu, W., Hancock, C., and Christian, K. J. (2012) The proline regulatory axis and cancer. Front. Oncol. 2, 60
-
(2012)
Front. Oncol.
, vol.2
, pp. 60
-
-
Phang, J.M.1
Liu, W.2
Hancock, C.3
Christian, K.J.4
-
10
-
-
77955619986
-
Proline metabolism and microenvironmental stress
-
Phang, J. M., Liu, W., and Zabirnyk, O. (2010) Proline metabolism and microenvironmental stress. Annu. Rev. Nutr. 30, 441-463
-
(2010)
Annu. Rev.Nutr.
, vol.30
, pp. 441-463
-
-
Phang, J.M.1
Liu, W.2
Zabirnyk, O.3
-
11
-
-
77950890848
-
Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy
-
Zabirnyk, O., Liu, W., Khalil, S., Sharma, A., and Phang, J. M. (2010) Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy. Carcinogenesis 31, 446-454
-
(2010)
Carcinogenesis
, vol.31
, pp. 446-454
-
-
Zabirnyk, O.1
Liu, W.2
Khalil, S.3
Sharma, A.4
Phang, J.M.5
-
12
-
-
84866544950
-
Proline dehydrogenase (oxidase), a mitochondrial tumor suppressor, and autophagy under the hypoxia microenvironment
-
Liu, W., and Phang, J. M. (2012) Proline dehydrogenase (oxidase), a mitochondrial tumor suppressor, and autophagy under the hypoxia microenvironment. Autophagy 8, 1407-1409
-
(2012)
Autophagy
, vol.8
, pp. 1407-1409
-
-
Liu, W.1
Phang, J.M.2
-
13
-
-
0032948179
-
The gene encoding proline dehydrogenase modulates sensorimotor gating in mice
-
Gogos, J. A., Santha, M., Takacs, Z., Beck, K. D., Luine, V., Lucas, L. R., Nadler, J. V., and Karayiorgou, M. (1999) The gene encoding proline dehydrogenase modulates sensorimotor gating in mice. Nat. Genet. 21, 434-439
-
(1999)
Nat. Genet.
, vol.21
, pp. 434-439
-
-
Gogos, J.A.1
Santha, M.2
Takacs, Z.3
Beck, K.D.4
Luine, V.5
Lucas, L.R.6
Nadler, J.V.7
Karayiorgou, M.8
-
14
-
-
0026716689
-
Molecular cloning and expression of a high affinity L-proline transporter expressed in putative glutamatergic pathways of rat brain
-
Fremeau, R. T., Jr., Caron, M. G., and Blakely, R. D. (1992) Molecular cloning and expression of a high affinity L-proline transporter expressed in putative glutamatergic pathways of rat brain. Neuron 8, 915-926
-
(1992)
Neuron
, vol.8
, pp. 915-926
-
-
Fremeau Jr. T, R.1
Caron, M.G.2
Blakely, R.D.3
-
15
-
-
0032906584
-
The mammalian brain high-affinity L-proline transporter is enriched preferentially in synaptic vesicles in a subpopulation of excitatory nerve terminals in rat forebrain
-
Renick, S. E., Kleven, D. T., Chan, J., Stenius, K., Milner, T. A., Pickel, V. M., and Fremeau, R. T., Jr. (1999) The mammalian brain high-affinity L-proline transporter is enriched preferentially in synaptic vesicles in a subpopulation of excitatory nerve terminals in rat forebrain. J. Neurosci. 19, 21-33
-
(1999)
J. Neurosci.
, vol.19
, pp. 21-33
-
-
Renick, S.E.1
Kleven, D.T.2
Chan, J.3
Stenius, K.4
Milner, T.A.5
Pickel, V.M.6
Fremeau, T.R.7
-
16
-
-
0030787937
-
Proline-induced potentiation of glutamate transmission
-
Cohen, S. M., and Nadler, J. V. (1997) Proline-induced potentiation of glutamate transmission. Brain Res. 761, 271-282
-
(1997)
Brain Res.
, vol.761
, pp. 271-282
-
-
Cohen, S.M.1
Nadler, J.V.2
-
17
-
-
27644478443
-
Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice
-
Paterlini, M., Zakharenko, S. S., Lai, W. S., Qin, J., Zhang, H., Mukai, J., Westphal, K. G., Olivier, B., Sulzer, D., Pavlidis, P., Siegelbaum, S. A., Karayiorgou, M., and Gogos, J. A. (2005) Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice. Nat. Neurosci. 8, 1586-1594
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 1586-1594
-
-
Paterlini, M.1
Zakharenko, S.S.2
Lai, W.S.3
Qin, J.4
Zhang, H.5
Mukai, J.6
Westphal, K.G.7
Olivier, B.8
Sulzer, D.9
Pavlidis, P.10
Siegelbaum, S.A.11
Karayiorgou, M.12
Gogos, J.A.13
-
18
-
-
0037168523
-
Genetic variation in the 22q11 locus and susceptibility to schizophrenia
-
Liu, H., Abecasis, G. R., Heath, S. C., Knowles, A., Demars, S., Chen, Y. J., Roos, J. L., Rapoport, J. L., Gogos, J. A., and Karayiorgou, M. (2002) Genetic variation in the 22q11 locus and susceptibility to schizophrenia. Proc. Natl. Acad. Sci. U.S.A. 99, 16859-16864
-
(2002)
Proc. Natl.Acad. Sci. U.S.A.
, vol.99
, pp. 16859-16864
-
-
Liu, H.1
Abecasis, G.R.2
Heath, S.C.3
Knowles, A.4
Demars, S.5
Chen, Y.J.6
Roos, J.L.7
Rapoport, J.L.8
Gogos, J.A.9
Karayiorgou, M.10
-
19
-
-
0842326677
-
Genetic variation at the 22q11 PRODH2/ DGCR6 locus presents an unusual pattern and increases susceptibility to schizophrenia
-
Liu, H., Heath, S. C., Sobin, C., Roos, J. L., Galke, B. L., Blundell, M. L., Lenane, M., Robertson, B., Wijsman, E. M., Rapoport, J. L., Gogos, J. A., and Karayiorgou, M. (2002) Genetic variation at the 22q11 PRODH2/ DGCR6 locus presents an unusual pattern and increases susceptibility to schizophrenia. Proc. Natl. Acad. Sci. U.S.A. 99, 3717-3722
-
(2002)
Proc. Natl.Acad. Sci. U.S.A.
, vol.99
, pp. 3717-3722
-
-
Liu, H.1
Heath, S.C.2
Sobin, C.3
Roos, J.L.4
Galke, B.L.5
Blundell, M.L.6
Lenane, M.7
Robertson, B.8
Wijsman, E.M.9
Rapoport, J.L.10
Gogos, J.A.11
Karayiorgou, M.12
-
20
-
-
20844445975
-
Hyperprolinemia is a risk factor for schizoaffective disorder
-
Jacquet, H., Demily, C., Houy, E., Hecketsweiler, B., Bou, J., Raux, G., Lerond, J., Allio, G., Haouzir, S., Tillaux, A., Bellegou, C., Fouldrin, G., Delamillieure, P., Ménard, J. F., Dollfus, S., D'Amato, T., Petit, M., Thibaut, F., Frébourg, T., and Campion, D. (2005) Hyperprolinemia is a risk factor for schizoaffective disorder. Mol. Psychiatry 10, 479-485
-
(2005)
Mol. Psychiatry
, vol.10
, pp. 479-485
-
-
Jacquet, H.1
Demily, C.2
Houy, E.3
Hecketsweiler, B.4
Bou, J.5
Raux, G.6
Lerond, J.7
Allio, G.8
Haouzir, S.9
Tillaux, A.10
Bellegou, C.11
Fouldrin, G.12
Delamillieure, P.13
Ménard, J.F.14
Dollfus, S.15
D'Amato, T.16
Petit, M.17
Thibaut, F.18
Frébourg, T.19
Campion, D.20
more..
-
21
-
-
67349160223
-
A risk PRODH haplotype affects sensorimotor gating, memory, schizotypy, and anxiety in healthy male subjects
-
Roussos, P., Giakoumaki, S. G., and Bitsios, P. (2009) A risk PRODH haplotype affects sensorimotor gating, memory, schizotypy, and anxiety in healthy male subjects. Biol. Psychiatry 65, 1063-1070
-
(2009)
Biol. Psychiatry
, vol.65
, pp. 1063-1070
-
-
Roussos, P.1
Giakoumaki, S.G.2
Bitsios, P.3
-
22
-
-
77954891060
-
Synapse pathology in psychiatric and neurologic disease
-
van Spronsen, M., and Hoogenraad, C. C. (2010) Synapse pathology in psychiatric and neurologic disease. Curr. Neurol. Neurosci. Rep 10, 207-214
-
(2010)
Curr. Neurol. Neurosci. Rep
, vol.10
, pp. 207-214
-
-
Van Spronsen, M.1
Hoogenraad, C.C.2
-
23
-
-
80052296956
-
Behavioral and neurochemical effects of proline
-
Wyse, A. T., and Netto, C. A. (2011) Behavioral and neurochemical effects of proline. Metab. Brain Dis 26, 159-172
-
(2011)
Metab. Brain Dis
, vol.26
, pp. 159-172
-
-
Wyse, A.T.1
Netto, C.A.2
-
24
-
-
0038136866
-
Pathogenesis of human immunodeficiency virus-induced neurological disease
-
Albright, A. V., Soldan, S. S., and González-Scarano, F. (2003) Pathogenesis of human immunodeficiency virus-induced neurological disease. J. Neurovirol. 9, 222-227
-
(2003)
J. Neurovirol.
, vol.9
, pp. 222-227
-
-
Albright, A.V.1
Soldan, S.S.2
González-Scarano, F.3
-
25
-
-
77957969916
-
Neurologic disease burden in treated HIV/AIDS predicts survival: A population-based study
-
Vivithanaporn, P., Heo, G., Gamble, J., Krentz, H. B., Hoke, A., Gill, M. J., and Power, C. (2010) Neurologic disease burden in treated HIV/AIDS predicts survival: a population-based study. Neurology 75, 1150-1158
-
(2010)
Neurology
, vol.75
, pp. 1150-1158
-
-
Vivithanaporn, P.1
Heo, G.2
Gamble, J.3
Krentz, H.B.4
Hoke, A.5
Gill, M.J.6
Power, C.7
-
26
-
-
77952149363
-
Does highly active antiretroviral therapy improve neurocognitive function? A systematic review
-
Joska, J. A., Gouse, H., Paul, R. H., Stein, D. J., and Flisher, A. J. (2010) Does highly active antiretroviral therapy improve neurocognitive function? A systematic review. J. Neurovirol. 16, 101-114
-
(2010)
J. Neurovirol.
, vol.16
, pp. 101-114
-
-
Joska, J.A.1
Gouse, H.2
Paul, R.H.3
Stein, D.J.4
Flisher, A.J.5
-
27
-
-
4644321592
-
Higher frequency of dementia in older HIV-1 individuals: The Hawaii aging with HIV-1 cohort
-
Valcour, V., Shikuma, C., Shiramizu, B., Watters, M., Poff, P., Selnes, O., Holck, P., Grove, J., and Sacktor, N. (2004) Higher frequency of dementia in older HIV-1 individuals: the Hawaii aging with HIV-1 cohort. Neurology 63, 822-827
-
(2004)
Neurology
, vol.63
, pp. 822-827
-
-
Valcour, V.1
Shikuma, C.2
Shiramizu, B.3
Watters, M.4
Poff, P.5
Selnes, O.6
Holck, P.7
Grove, J.8
Sacktor, N.9
-
28
-
-
77952940200
-
Human immunodeficiency virus-associated neurocognitive disorders: Mind the gap
-
McArthur, J. C., Steiner, J., Sacktor, N., and Nath, A. (2010) Human immunodeficiency virus-associated neurocognitive disorders: mind the gap. Ann. Neurol. 67, 699-714
-
(2010)
Ann. Neurol.
, vol.67
, pp. 699-714
-
-
McArthur, J.C.1
Steiner, J.2
Sacktor, N.3
Nath, A.4
-
29
-
-
0034092005
-
Human immunodeficiency virus-associated dementia
-
Clifford, D. B. (2000) Human immunodeficiency virus-associated dementia. Arch. Neurol. 57, 321-324
-
(2000)
Arch. Neurol.
, vol.57
, pp. 321-324
-
-
Clifford, D.B.1
-
30
-
-
84901818666
-
Viral and cellular factors underlying neuropathogenesis in HIV-associated neurocognitive disorders (HAND)
-
Rao, V. R., Ruiz, A. P., and Prasad, V. R. (2014) Viral and cellular factors underlying neuropathogenesis in HIV-associated neurocognitive disorders (HAND). AIDS Res. Ther. 11, 13
-
(2014)
AIDS Res.Ther.
, vol.11
, pp. 13
-
-
Rao, V.R.1
Ruiz, A.P.2
Prasad, V.R.3
-
31
-
-
0035912198
-
Pathways to neuronal injury and apoptosis in HIV-associated dementia
-
Kaul, M., Garden, G. A., and Lipton, S. A. (2001) Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 410, 988-994
-
(2001)
Nature
, vol.410
, pp. 988-994
-
-
Kaul, M.1
Garden, G.A.2
Lipton, S.A.3
-
32
-
-
0036891081
-
Human immunodeficiency virus (HIV) proteins in neuropathogenesis of HIV dementia
-
Nath, A. (2002) Human immunodeficiency virus (HIV) proteins in neuropathogenesis of HIV dementia. J. Infect. Dis. 186, S193-S198
-
(2002)
J. Infect.Dis.
, vol.186
, pp. S193-S198
-
-
Nath, A.1
-
34
-
-
84856242946
-
Neurotoxicity of human immunodeficiency virus-1: Viral proteins and axonal transport
-
Mocchetti, I., Bachis, A., and Avdoshina, V. (2012) Neurotoxicity of human immunodeficiency virus-1: viral proteins and axonal transport. Neurotox. Res. 21, 79-89
-
(2012)
Neurotox. Res.
, vol.21
, pp. 79-89
-
-
Mocchetti, I.1
Bachis, A.2
Avdoshina, V.3
-
35
-
-
2442593764
-
Human immunodeficiency virus type 1 protein gp120 causes neuronal cell death in the rat brain by activating caspases
-
Acquas, E., Bachis, A., Nosheny, R. L., Cernak, I., and Mocchetti, I. (2004) Human immunodeficiency virus type 1 protein gp120 causes neuronal cell death in the rat brain by activating caspases. Neurotox. Res. 5, 605-615
-
(2004)
Neurotox. Res.
, vol.5
, pp. 605-615
-
-
Acquas, E.1
Bachis, A.2
Nosheny, R.L.3
Cernak, I.4
Mocchetti, I.5
-
36
-
-
71549124077
-
Dopaminergic neurotoxicity of HIV-1 gp120: Reactive oxygen species as signaling intermediates
-
Agrawal, L., Louboutin, J. P., Marusich, E., Reyes, B. A., Van Bockstaele, E. J., and Strayer, D. S. (2010) Dopaminergic neurotoxicity of HIV-1 gp120: reactive oxygen species as signaling intermediates. Brain Res 1306, 116-130
-
(2010)
Brain Res
, vol.1306
, pp. 116-130
-
-
Agrawal, L.1
Louboutin, J.P.2
Marusich, E.3
Reyes, B.A.4
Van Bockstaele, E.J.5
Strayer, D.S.6
-
37
-
-
33846828051
-
Oxidative stress and therapeutic approaches in HIV dementia
-
Steiner, J., Haughey, N., Li, W., Venkatesan, A., Anderson, C., Reid, R., Malpica, T., Pocernich, C., Butterfield, D. A., and Nath, A. (2006) Oxidative stress and therapeutic approaches in HIV dementia. Antioxid. Redox Signal. 8, 2089-2100
-
(2006)
Antioxid. Redox Signal.
, vol.8
, pp. 2089-2100
-
-
Steiner, J.1
Haughey, N.2
Li, W.3
Venkatesan, A.4
Anderson, C.5
Reid, R.6
Malpica, T.7
Pocernich, C.8
Butterfield, D.A.9
Nath, A.10
-
38
-
-
77649132973
-
Preferential sensitivity of human dopaminergic neurons to gp120-induced oxidative damage
-
Hu, S., Sheng, W. S., Lokensgard, J. R., Peterson, P. K., and Rock, R. B. (2009) Preferential sensitivity of human dopaminergic neurons to gp120-induced oxidative damage. J. Neurovirol. 15, 401-410
-
(2009)
J. Neurovirol.
, vol.15
, pp. 401-410
-
-
Hu, S.1
Sheng, W.S.2
Lokensgard, J.R.3
Peterson, P.K.4
Rock, R.B.5
-
39
-
-
7444266728
-
Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase
-
Jana, A., and Pahan, K. (2004) Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase. J. Neurosci. 24, 9531-9540
-
(2004)
J. Neurosci.
, vol.24
, pp. 9531-9540
-
-
Jana, A.1
Pahan, K.2
-
40
-
-
84858141312
-
Blood-brain barrier abnormalities caused by HIV-1 gp120: Mechanistic and therapeutic implications
-
Louboutin, J. P., and Strayer, D. S. (2012) Blood-brain barrier abnormalities caused by HIV-1 gp120: mechanistic and therapeutic implications. ScientificWorldJournal 2012, 482575
-
(2012)
ScientificWorldJournal
, vol.2012
, pp. 482575
-
-
Louboutin, J.P.1
Strayer, D.S.2
-
41
-
-
78149455160
-
Cocaine potentiates astrocyte toxicity mediated by human immunodeficiency virus (HIV-1) protein gp120
-
Yang, Y., Yao, H., Lu, Y., Wang, C., and Buch, S. (2010) Cocaine potentiates astrocyte toxicity mediated by human immunodeficiency virus (HIV-1) protein gp120. PLoS ONE 5, e13427
-
(2010)
PLoS ONE
, vol.5
, pp. e13427
-
-
Yang, Y.1
Yao, H.2
Lu, Y.3
Wang, C.4
Buch, S.5
-
42
-
-
84869459812
-
Autophagy is a protective response to ethanol neurotoxicity
-
Chen, G., Ke, Z., Xu, M., Liao, M., Wang, X., Qi, Y., Zhang, T., Frank, J. A., Bower, K. A., Shi, X., and Luo, J. (2012) Autophagy is a protective response to ethanol neurotoxicity. Autophagy 8, 1577-1589
-
(2012)
Autophagy
, vol.8
, pp. 1577-1589
-
-
Chen, G.1
Ke, Z.2
Xu, M.3
Liao, M.4
Wang, X.5
Qi, Y.6
Zhang, T.7
Frank, J.A.8
Bower, K.A.9
Shi, X.10
Luo, J.11
-
43
-
-
67650087634
-
Regulation and function of proline oxidase under nutrient stress
-
Pandhare, J., Donald, S. P., Cooper, S. K., and Phang, J. M. (2009) Regulation and function of proline oxidase under nutrient stress. J. Cell. Biochem. 107, 759-768
-
(2009)
J. Cell.Biochem.
, vol.107
, pp. 759-768
-
-
Pandhare, J.1
Donald, S.P.2
Cooper, S.K.3
Phang, J.M.4
-
44
-
-
84856821006
-
Signal transduction by mitochondrial oxidants
-
Finkel, T. (2012) Signal transduction by mitochondrial oxidants. J. Biol. Chem. 287, 4434-4440
-
(2012)
J. Biol.Chem.
, vol.287
, pp. 4434-4440
-
-
Finkel, T.1
-
45
-
-
76049083966
-
Reactive oxygen species, cellular redox systems, and apoptosis
-
Circu, M. L., and Aw, T. Y. (2010) Reactive oxygen species, cellular redox systems, and apoptosis. Free Radic. Biol. Med. 48, 749-762
-
(2010)
Free Radic. Biol. Med.
, vol.48
, pp. 749-762
-
-
Circu, M.L.1
Aw, T.Y.2
-
46
-
-
0034699433
-
Flow cytometry of apoptotic cell death
-
Vermes, I., Haanen, C., and Reutelingsperger, C. (2000) Flow cytometry of apoptotic cell death. J. Immunol. Methods 243, 167-190
-
(2000)
J. Immunol.Methods
, vol.243
, pp. 167-190
-
-
Vermes, I.1
Haanen, C.2
Reutelingsperger, C.3
-
47
-
-
78650328444
-
Autophagy basics
-
Tanida, I. (2011) Autophagy basics. Microbiol Immunol 55, 1-11
-
(2011)
Microbiol Immunol
, vol.55
, pp. 1-11
-
-
Tanida, I.1
-
48
-
-
79956095420
-
Autophagosome formation and molecular mechanism of autophagy
-
Tanida, I. (2011) Autophagosome formation and molecular mechanism of autophagy. Antioxid. Redox Signal. 14, 2201-2214
-
(2011)
Antioxid. Redox Signal.
, vol.14
, pp. 2201-2214
-
-
Tanida, I.1
-
49
-
-
84555195856
-
Autophagy, mitochondria and oxidative stress: Cross-talk and redox signalling
-
Lee, J., Giordano, S., and Zhang, J. (2012) Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling. Biochem. J. 441, 523-540
-
(2012)
Biochem. J.
, vol.441
, pp. 523-540
-
-
Lee, J.1
Giordano, S.2
Zhang, J.3
-
50
-
-
72549095406
-
Regulation mechanisms and signaling pathways of autophagy
-
He, C., and Klionsky, D. J. (2009) Regulation mechanisms and signaling pathways of autophagy. Annu. Rev. Genet. 43, 67-93
-
(2009)
Annu. Rev.Genet.
, vol.43
, pp. 67-93
-
-
He, C.1
Klionsky, D.J.2
-
51
-
-
84863896166
-
Proline oxidase promotes tumor cell survival in hypoxic tumor microenvironments
-
Liu, W., Glunde, K., Bhujwalla, Z. M., Raman, V., Sharma, A., and Phang, J. M. (2012) Proline oxidase promotes tumor cell survival in hypoxic tumor microenvironments. Cancer Res. 72, 3677-3686
-
(2012)
Cancer Res.
, vol.72
, pp. 3677-3686
-
-
Liu, W.1
Glunde, K.2
Bhujwalla, Z.M.3
Raman, V.4
Sharma, A.5
Phang, J.M.6
-
52
-
-
59349105233
-
Monitoring autophagy in mammalian cultured cells through the dynamics of LC3
-
Kimura, S., Fujita, N., Noda, T., and Yoshimori, T. (2009) Monitoring autophagy in mammalian cultured cells through the dynamics of LC3. Methods Enzymol. 452, 1-12
-
(2009)
Methods Enzymol.
, vol.452
, pp. 1-12
-
-
Kimura, S.1
Fujita, N.2
Noda, T.3
Yoshimori, T.4
-
53
-
-
58149083873
-
Selective turnover of p62/A170/SQSTM1 by autophagy
-
Ichimura, Y., Kominami, E., Tanaka, K., and Komatsu, M. (2008) Selective turnover of p62/A170/SQSTM1 by autophagy. Autophagy 4, 1063-1066
-
(2008)
Autophagy
, vol.4
, pp. 1063-1066
-
-
Ichimura, Y.1
Kominami, E.2
Tanaka, K.3
Komatsu, M.4
-
54
-
-
84898729030
-
How can I halt thee? The puzzles involved in autophagic inhibition
-
Vinod, V., Padmakrishnan, C. J., Vijayan, B., and Gopala, S. (2014) 'How can I halt thee?' The puzzles involved in autophagic inhibition. Pharmacol. Res. 82, 1-8
-
(2014)
Pharmacol. Res.
, vol.82
, pp. 1-8
-
-
Vinod, V.1
Padmakrishnan, C.J.2
Vijayan, B.3
Gopala, S.4
-
55
-
-
35648945862
-
The glial response to CNS HIV infection includes p53 activation and increased expression of p53 target genes
-
Jayadev, S., Yun, B., Nguyen, H., Yokoo, H., Morrison, R. S., and Garden, G. A. (2007) The glial response to CNS HIV infection includes p53 activation and increased expression of p53 target genes. J Neuroimmune Pharmacol. 2, 359-370
-
(2007)
J Neuroimmune Pharmacol
, vol.2
, pp. 359-370
-
-
Jayadev, S.1
Yun, B.2
Nguyen, H.3
Yokoo, H.4
Morrison, R.S.5
Garden, G.A.6
-
56
-
-
23644436050
-
Regulation of neuronal P53 activity by CXCR 4
-
Khan, M. Z., Shimizu, S., Patel, J. P., Nelson, A., Le, M. T., Mullen-Przeworski, A., Brandimarti, R., Fatatis, A., and Meucci, O. (2005) Regulation of neuronal P53 activity by CXCR 4. Mol. Cell Neurosci. 30, 58-66
-
(2005)
Mol. Cell Neurosci.
, vol.30
, pp. 58-66
-
-
Khan, M.Z.1
Shimizu, S.2
Patel, J.P.3
Nelson, A.4
Le, M.T.5
Mullen-Przeworski, A.6
Brandimarti, R.7
Fatatis, A.8
Meucci, O.9
-
57
-
-
18144380368
-
The multiple roles of p53 in the pathogenesis of HIV associated dementia
-
Garden, G. A., and Morrison, R. S. (2005) The multiple roles of p53 in the pathogenesis of HIV associated dementia. Biochem. Biophys. Res. Commun. 331, 799-809
-
(2005)
Biochem. Biophys.Res. Commun.
, vol.331
, pp. 799-809
-
-
Garden, G.A.1
Morrison, R.S.2
-
58
-
-
0030930366
-
A model for p53-induced apoptosis
-
Polyak, K., Xia, Y., Zweier, J. L., Kinzler, K. W., and Vogelstein, B. (1997) A model for p53-induced apoptosis. Nature 389, 300-305
-
(1997)
Nature
, vol.389
, pp. 300-305
-
-
Polyak, K.1
Xia, Y.2
Zweier, J.L.3
Kinzler, K.W.4
Vogelstein, B.5
-
59
-
-
78649833334
-
p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation
-
Scherz-Shouval, R., Weidberg, H., Gonen, C., Wilder, S., Elazar, Z., and Oren, M. (2010) p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation. Proc. Natl. Acad. Sci. U.S.A. 107, 18511-18516
-
(2010)
Proc. Natl.Acad. Sci. U.S.A.
, vol.107
, pp. 18511-18516
-
-
Scherz-Shouval, R.1
Weidberg, H.2
Gonen, C.3
Wilder, S.4
Elazar, Z.5
Oren, M.6
-
60
-
-
1342326797
-
Mitochondrial apoptosis induced by the HIV-1 envelope
-
Castedo, M., Perfettini, J. L., Andreau, K., Roumier, T., Piacentini, M., and Kroemer, G. (2003) Mitochondrial apoptosis induced by the HIV-1 envelope. Ann. N.Y. Acad. Sci. 1010, 19-28
-
(2003)
Ann. N.Y. Acad. Sci.
, vol.1010
, pp. 19-28
-
-
Castedo, M.1
Perfettini, J.L.2
Andreau, K.3
Roumier, T.4
Piacentini, M.5
Kroemer, G.6
-
61
-
-
0032564406
-
Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity
-
Meucci, O., Fatatis, A., Simen, A. A., Bushell, T. J., Gray, P. W., and Miller, R. J. (1998) Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity. Proc. Natl. Acad. Sci. U.S.A. 95, 14500-14505
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 14500-14505
-
-
Meucci, O.1
Fatatis, A.2
Simen, A.A.3
Bushell, T.J.4
Gray, P.W.5
Miller, R.J.6
-
62
-
-
84896808624
-
β-Arrestin1 and distinct CXCR4 structures are required for stromal derived factor-1 to downregulate CXCR4 cell-surface levels in neuroblastoma
-
Clift, I. C., Bamidele, A. O., Rodriguez-Ramirez, C., Kremer, K. N., and Hedin, K. E. (2014) β-Arrestin1 and distinct CXCR4 structures are required for stromal derived factor-1 to downregulate CXCR4 cell-surface levels in neuroblastoma. Mol. Pharmacol. 85, 542-552
-
(2014)
Mol. Pharmacol.
, vol.85
, pp. 542-552
-
-
Clift, I.C.1
Bamidele, A.O.2
Rodriguez-Ramirez, C.3
Kremer, K.N.4
Hedin, K.E.5
-
63
-
-
22744435902
-
Mechanisms of apoptosis induction by the HIV-1 envelope
-
Perfettini, J. L., Castedo, M., Roumier, T., Andreau, K., Nardacci, R., Piacentini, M., and Kroemer, G. (2005) Mechanisms of apoptosis induction by the HIV-1 envelope. Cell Death Differ. 12, 916-923
-
(2005)
Cell Death Differ
, vol.12
, pp. 916-923
-
-
Perfettini, J.L.1
Castedo, M.2
Roumier, T.3
Andreau, K.4
Nardacci, R.5
Piacentini, M.6
Kroemer, G.7
-
64
-
-
0035887446
-
Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation
-
Castedo, M., Ferri, K. F., Blanco, J., Roumier, T., Larochette, N., Barretina, J., Amendola, A., Nardacci, R., Métivier, D., Este, J. A., Piacentini, M., and Kroemer, G. (2001) Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation. J. Exp. Med. 194, 1097-1110
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1097-1110
-
-
Castedo, M.1
Ferri, K.F.2
Blanco, J.3
Roumier, T.4
Larochette, N.5
Barretina, J.6
Amendola, A.7
Nardacci, R.8
Métivier, D.9
Este, J.A.10
Piacentini, M.11
Kroemer, G.12
-
65
-
-
33750079286
-
Human immunodeficiency virus gp120-induced apoptosis of human neuroblastoma cells in the absence of CXCR4 internalization
-
Bardi, G., Sengupta, R., Khan, M. Z., Patel, J. P., and Meucci, O. (2006) Human immunodeficiency virus gp120-induced apoptosis of human neuroblastoma cells in the absence of CXCR4 internalization. J. Neurovirol. 12, 211-218
-
(2006)
J. Neurovirol.
, vol.12
, pp. 211-218
-
-
Bardi, G.1
Sengupta, R.2
Khan, M.Z.3
Patel, J.P.4
Meucci, O.5
-
66
-
-
0038784645
-
The chemokine receptor CXCR4 regulates cell-cycle proteins in neurons
-
Khan, M. Z., Brandimarti, R., Musser, B. J., Resue, D. M., Fatatis, A., and Meucci, O. (2003) The chemokine receptor CXCR4 regulates cell-cycle proteins in neurons. J. Neurovirol. 9, 300-314
-
(2003)
J. Neurovirol.
, vol.9
, pp. 300-314
-
-
Khan, M.Z.1
Brandimarti, R.2
Musser, B.J.3
Resue, D.M.4
Fatatis, A.5
Meucci, O.6
-
67
-
-
0028209166
-
Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100
-
De Clercq, E., Yamamoto, N., Pauwels, R., Balzarini, J., Witvrouw, M., De Vreese, K., Debyser, Z., Rosenwirth, B., Peichl, P., and Datema, R. (1994) Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100. Antimicrob. Agents Chemother. 38, 668-674
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 668-674
-
-
De Clercq, E.1
Yamamoto, N.2
Pauwels, R.3
Balzarini, J.4
Witvrouw, M.5
De Vreese, K.6
Debyser, Z.7
Rosenwirth, B.8
Peichl, P.9
Datema, R.10
-
68
-
-
0029067663
-
Synthesis and structure-activity relationships of phenylenebis(methylene)-linked bis-tetraazamacrocycles that inhibit HIV replication Effects of macrocyclic ring size and substituents on the aromatic linker
-
Bridger, G. J., Skerlj, R. T., Thornton, D., Padmanabhan, S., Martellucci, S. A., Henson, G. W., Abrams, M. J., Yamamoto, N., De Vreese, K., and Pauwels, R. (1995) Synthesis and structure-activity relationships of phenylenebis(methylene)-linked bis-tetraazamacrocycles that inhibit HIV replication. Effects of macrocyclic ring size and substituents on the aromatic linker. J. Med. Chem. 38, 366-378
-
(1995)
J. Med. Chem.
, vol.38
, pp. 366-378
-
-
Bridger, G.J.1
Skerlj, R.T.2
Thornton, D.3
Padmanabhan, S.4
Martellucci, S.A.5
Henson, G.W.6
Abrams, M.J.7
Yamamoto, N.8
De Vreese, K.9
Pauwels, R.10
-
69
-
-
0034120373
-
Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers
-
Hendrix, C. W., Flexner, C., MacFarland, R. T., Giandomenico, C., Fuchs, E. J., Redpath, E., Bridger, G., and Henson, G. W. (2000) Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers. Antimicrob. Agents Chemother. 44, 1667-1673
-
(2000)
Antimicrob. Agents Chemother
, vol.44
, pp. 1667-1673
-
-
Hendrix, C.W.1
Flexner, C.2
MacFarland, R.T.3
Giandomenico, C.4
Fuchs, E.J.5
Redpath, E.6
Bridger, G.7
Henson, G.W.8
-
70
-
-
78249240388
-
Mechanisms of HIV envelope-induced T lymphocyte apoptosis
-
Wan, Z. T., and Chen, X. L. (2010) Mechanisms of HIV envelope-induced T lymphocyte apoptosis. Virol. Sin. 25, 307-315
-
(2010)
Virol. Sin.
, vol.25
, pp. 307-315
-
-
Wan, Z.T.1
Chen, X.L.2
-
71
-
-
0037195080
-
Cardiomyocytes undergo apoptosis in human immunodeficiency virus cardiomyopathy through mitochondrion- and death receptor-controlled pathways
-
Twu, C., Liu, N. Q., Popik, W., Bukrinsky, M., Sayre, J., Roberts, J., Rania, S., Bramhandam, V., Roos, K. P., MacLellan, W. R., and Fiala, M. (2002) Cardiomyocytes undergo apoptosis in human immunodeficiency virus cardiomyopathy through mitochondrion- and death receptor-controlled pathways. Proc. Natl. Acad. Sci. U.S.A. 99, 14386-14391
-
(2002)
Proc. Natl.Acad. Sci. U.S.A.
, vol.99
, pp. 14386-14391
-
-
Twu, C.1
Liu, N.Q.2
Popik, W.3
Bukrinsky, M.4
Sayre, J.5
Roberts, J.6
Rania, S.7
Bramhandam, V.8
Roos, K.P.9
MacLellan, W.R.10
Fiala, M.11
-
72
-
-
77649137126
-
GCP II inhibition rescues neurons from gp120IIIB-induced neurotoxicity
-
Thomas, A. G., Bodner, A., Ghadge, G., Roos, R. P., and Slusher, B. S. (2009) GCP II inhibition rescues neurons from gp120IIIB-induced neurotoxicity. J. Neurovirol. 15, 449-457
-
(2009)
J. Neurovirol.
, vol.15
, pp. 449-457
-
-
Thomas, A.G.1
Bodner, A.2
Ghadge, G.3
Roos, R.P.4
Slusher, B.S.5
-
73
-
-
54749113722
-
The metabolism of proline as microenvironmental stress substrate
-
Phang, J. M., Pandhare, J., and Liu, Y. (2008) The metabolism of proline as microenvironmental stress substrate. J. Nutr. 138, 2008S-2015S
-
(2008)
J. Nutr.
, vol.138
, pp. 2008S-2015S
-
-
Phang, J.M.1
Pandhare, J.2
Liu, Y.3
-
74
-
-
0034700139
-
Differential gene expression in p53-mediated apoptosis-resistant vs apoptosis-sensitive tumor cell lines
-
Maxwell, S. A., and Davis, G. E. (2000) Differential gene expression in p53-mediated apoptosis-resistant vs. apoptosis-sensitive tumor cell lines. Proc. Natl. Acad. Sci. U.S.A. 97, 13009-13014
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 13009-13014
-
-
Maxwell, S.A.1
Davis, G.E.2
-
75
-
-
84931958134
-
ROS and autophagy: Interactions and molecular regulatory mechanisms
-
Li, L., Tan, J., Miao, Y., Lei, P., and Zhang, Q. (2015) ROS and autophagy: interactions and molecular regulatory mechanisms. Cell Mol Neurobiol. 35, 615-621
-
(2015)
Cell Mol Neurobiol.
, vol.35
, pp. 615-621
-
-
Li, L.1
Tan, J.2
Miao, Y.3
Lei, P.4
Zhang, Q.5
-
76
-
-
60749108379
-
Regulation of autophagy by reactive oxygen species (ROS): Implications for cancer progression and treatment
-
Azad, M. B., Chen, Y., and Gibson, S. B. (2009) Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment. Antioxid. Redox Signal. 11, 777-790
-
(2009)
Antioxid. Redox Signal.
, vol.11
, pp. 777-790
-
-
Azad, M.B.1
Chen, Y.2
Gibson, S.B.3
-
77
-
-
84866155363
-
Neuronal autophagy: A housekeeper or a fighter in neuronal cell survival?
-
Lee, J. A. (2012) Neuronal autophagy: a housekeeper or a fighter in neuronal cell survival? Exp. Neurobiol. 21, 1-8
-
(2012)
Exp. Neurobiol.
, vol.21
, pp. 1-8
-
-
Lee, J.A.1
-
78
-
-
78649299872
-
Autophagy in the central nervous system: Implications for neurodegenerative disorders CNS Neurol
-
Xilouri, M., and Stefanis, L. (2010) Autophagy in the central nervous system: implications for neurodegenerative disorders. CNS Neurol. Disord. Drug Targets 9, 701-719
-
(2010)
Disord. Drug Targets
, vol.9
, pp. 701-719
-
-
Xilouri, M.1
Stefanis, L.2
-
79
-
-
26444587508
-
Macroautophagy-A novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
-
Yu, W. H., Cuervo, A. M., Kumar, A., Peterhoff, C. M., Schmidt, S. D., Lee, J. H., Mohan, P. S., Mercken, M., Farmery, M. R., Tjernberg, L. O., Jiang, Y., Duff, K., Uchiyama, Y., Näslund, J., Mathews, P. M., Cataldo, A. M., and Nixon, R. A. (2005) Macroautophagy-a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease. J. Cell Biol. 171, 87-98
-
(2005)
J. Cell Biol.
, vol.171
, pp. 87-98
-
-
Yu, W.H.1
Cuervo, A.M.2
Kumar, A.3
Peterhoff, C.M.4
Schmidt, S.D.5
Lee, J.H.6
Mohan, P.S.7
Mercken, M.8
Farmery, M.R.9
Tjernberg, L.O.10
Jiang, Y.11
Duff, K.12
Uchiyama, Y.13
Näslund, J.14
Mathews, P.M.15
Cataldo, A.M.16
Nixon, R.A.17
-
80
-
-
44149124887
-
Autophagy in neuroprotection and neurodegeneration: A question of balance
-
3rd
-
Cherra, S. J., 3rd, and Chu, C. T. (2008) Autophagy in neuroprotection and neurodegeneration: A question of balance. Future Neurol. 3, 309-323
-
(2008)
Future Neurol.
, Issue.3
, pp. 309-323
-
-
Cherra, S.J.1
Chu, C.T.2
-
81
-
-
79956204926
-
Autophagy is increased in postmortem brains of persons with HIV-1-associated encephalitis
-
Zhou, D., Masliah, E., and Spector, S. A. (2011) Autophagy is increased in postmortem brains of persons with HIV-1-associated encephalitis. J. Infect. Dis. 203, 1647-1657
-
(2011)
J. Infect.Dis.
, vol.203
, pp. 1647-1657
-
-
Zhou, D.1
Masliah, E.2
Spector, S.A.3
-
82
-
-
33746691954
-
Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4
-
Espert, L., Denizot, M., Grimaldi, M., Robert-Hebmann, V., Gay, B., Varbanov, M., Codogno, P., and Biard-Piechaczyk, M. (2006) Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4. J. Clin. Invest. 116, 2161-2172
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2161-2172
-
-
Espert, L.1
Denizot, M.2
Grimaldi, M.3
Robert-Hebmann, V.4
Gay, B.5
Varbanov, M.6
Codogno, P.7
Biard-Piechaczyk, M.8
|