GCP II inhibition rescues neurons from gp120IIIB-induced neurotoxicity

Journal of NeuroVirology

Volumn 15, Issue 5-6, 2009, Pages 449-457

  Thomas, Ajit G ^a   Bodner, Amos ^b   Ghadge, Ghanashyam ^b   Roos, Raymond P ^b   Slusher, Barbara S ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

Author keywords

GCP II; Glutamate; HIV associated dementia; Metabotropic glutamate receptors; NAAG; TGF

Indexed keywords

2 (PHOSPHONOMETHYL)PENTANEDIOIC ACID; CHEMOKINE RECEPTOR CXCR4; GLUTAMATE CARBOXYPEPTIDASE II; GLUTAMATE CARBOXYPEPTIDASE II INHIBITOR; GLUTAMIC ACID; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 120IIIB; METABOTROPIC RECEPTOR 3; N ACETYLASPARTYLGLUTAMIC ACID; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL CELL; APOPTOSIS; ARTICLE; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; DEMENTIA; DRUG POTENCY; DRUG SELECTIVITY; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; EXCITOTOXICITY; GLIA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; HUMAN IMMUNODEFICIENCY VIRUS ASSOCIATED DEMENTIA; IN VITRO STUDY; NERVE CELL LESION; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT;

AIDS DEMENTIA COMPLEX; ANIMALS; APOPTOSIS; CELLS, CULTURED; DIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GLUTAMATE CARBOXYPEPTIDASE II; HIPPOCAMPUS; HIV ENVELOPE PROTEIN GP120; NEUROGLIA; NEURONS; NEUROPROTECTIVE AGENTS; ORGANOPHOSPHORUS COMPOUNDS; RATS; RECEPTORS, METABOTROPIC GLUTAMATE; TRANSFORMING GROWTH FACTOR BETA;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 77649137126     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.3109/13550280903350598     Document Type: Article

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