Pathogen Virulence Impedes Mutualist-Mediated Enhancement of Host Juvenile Growth via Inhibition of Protein Digestion

Cell Host and Microbe

Volumn 18, Issue 4, 2015, Pages 445-455

  Erkosar, Berra ^a,b   Storelli, Gilles ^a   Mitchell, Mélanie ^a   Bozonnet, Loan ^a   Bozonnet, Noémie ^a,c   Leulier, François ^a  

^a UNIVERSITÉ DE LYON   (France)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; AMINO ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEPTIDASE; PEPTIDOGLYCAN; PEPTIDOGLYCAN RECOGNITION PROTEIN; PEPTIDOGLYCAN RECOGNITION PROTEIN LE; PROTEIN IMD; PROTEIN RELISH; UNCLASSIFIED DRUG; PEPTIDE HYDROLASE;

ARTICLE; BACTERIAL VIRULENCE; DROSOPHILA; ENZYME ACTIVITY; GENE EXPRESSION; IMMUNITY; LACTOBACILLUS PLANTARUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ANTIBIOSIS; ENZYMOLOGY; GROWTH, DEVELOPMENT AND AGING; HOST PATHOGEN INTERACTION; LARVA; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; SYMBIOSIS; VIRULENCE;

ANIMALS; ANTIBIOSIS; DROSOPHILA; HOST-PATHOGEN INTERACTIONS; LACTOBACILLUS PLANTARUM; LARVA; PEPTIDE HYDROLASES; PROTEOLYSIS; SYMBIOSIS; VIRULENCE;

EID: 84944241894     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2015.09.001     Document Type: Article

References (43)

1. K. Aggarwal, F. Rus, C. Vriesema-Magnuson, D. Ertürk-Hasdemir, N. Paquette, and N. Silverman Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway PLoS Pathog. 4 2008 e1000120
2. J.S. Ayres, and D.S. Schneider The role of anorexia in resistance and tolerance to infections in Drosophila PLoS Biol. 7 2009 e1000150
3. A. Basset, P. Tzou, B. Lemaitre, and F. Boccard A single gene that promotes interaction of a phytopathogenic bacterium with its insect vector, Drosophila melanogaster EMBO Rep. 4 2003 205 209
4. J.E. Blum, C.N. Fischer, J. Miles, and J. Handelsman Frequent replenishment sustains the beneficial microbiome of Drosophila melanogaster MBio 4 2013 e00860-e13
5. V. Bosco-Drayon, M. Poidevin, I.G. Boneca, K. Narbonne-Reveau, J. Royet, and B. Charroux Peptidoglycan sensing by the receptor PGRP-LE in the Drosophila gut induces immune responses to infectious bacteria and tolerance to microbiota Cell Host Microbe 12 2012 153 165
6. N.A. Broderick A common origin for immunity and digestion Front. Immunol. 6 2015 72
7. N.A. Broderick, N. Buchon, and B. Lemaitre Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology MBio 5 2014 e01117-e14
8. T. Brummel, A. Ching, L. Seroude, A.F. Simon, and S. Benzer Drosophila lifespan enhancement by exogenous bacteria Proc. Natl. Acad. Sci. USA 101 2004 12974 12979
9. N. Buchon, N.A. Broderick, S. Chakrabarti, and B. Lemaitre Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila Genes Dev. 23 2009 2333 2344
10. N. Buchon, N.A. Broderick, M. Poidevin, S. Pradervand, and B. Lemaitre Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation Cell Host Microbe 5 2009 200 211
11. N. Buchon, N.A. Broderick, and B. Lemaitre Gut homeostasis in a microbial world: insights from Drosophila melanogaster Nat. Rev. Microbiol. 11 2013 615 626
12. M.C. Chambers, K.H. Song, and D.S. Schneider Listeria monocytogenes infection causes metabolic shifts in Drosophila melanogaster PLoS ONE 7 2012 e50679
13. R.I. Clark, S.W. Tan, C.B. Péan, U. Roostalu, V. Vivancos, K. Bronda, M. Pilátová, J. Fu, D.W. Walker, R. Berdeaux, and et al. MEF2 is an in vivo immune-metabolic switch Cell 155 2013 435 447
14. E. De Gregorio, P.T. Spellman, P. Tzou, G.M. Rubin, and B. Lemaitre The Toll and Imd pathways are the major regulators of the immune response in Drosophila EMBO J. 21 2002 2568 2579
15. M.S. Dionne, L.N. Pham, M. Shirasu-Hiza, and D.S. Schneider Akt and FOXO dysregulation contribute to infection-induced wasting in Drosophila Curr. Biol. 16 2006 1977 1985
16. A.E. Douglas The Symbiotic Habit 2010 Princeton University Press
17. B. Erkosar, G. Storelli, A. Defaye, and F. Leulier Host-intestinal microbiota mutualism: "learning on the fly" Cell Host Microbe 13 2013 8 14
18. B. Erkosar, A. Defaye, N. Bozonnet, D. Puthier, J. Royet, and F. Leulier Drosophila microbiota modulates host metabolic gene expression via IMD/NF-κB signaling PLoS ONE 9 2014 e94729
19. L. Guo, J. Karpac, S.L. Tran, and H. Jasper PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan Cell 156 2014 109 122
20. S. Hoppler, and M. Bienz Specification of a single cell type by a Drosophila homeotic gene Cell 76 1994 689 702
21. T. Kaneko, T. Yano, K. Aggarwal, J.H. Lim, K. Ueda, Y. Oshima, C. Peach, D. Erturk-Hasdemir, W.E. Goldman, B.H. Oh, and et al. PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan Nat. Immunol. 7 2006 715 723
22. A. Kleino, H. Myllymäki, J. Kallio, L.M. Vanha-aho, K. Oksanen, J. Ulvila, D. Hultmark, S. Valanne, and M. Rämet Pirk is a negative regulator of the Drosophila Imd pathway J. Immunol. 180 2008 5413 5422
23. W.J. Lee, and P.T. Brey How microbiomes influence metazoan development: insights from history and Drosophila modeling of gut-microbe interactions Annu. Rev. Cell Dev. Biol. 29 2013 571 592
24. B. Lemaitre, and I. Miguel-Aliaga The digestive tract of Drosophila melanogaster Annu. Rev. Genet. 47 2013 377 404
25. F. Leulier, A. Rodriguez, R.S. Khush, J.M. Abrams, and B. Lemaitre The Drosophila caspase Dredd is required to resist gram-negative bacterial infection EMBO Rep. 1 2000 353 358
26. N. Lhocine, P.S. Ribeiro, N. Buchon, A. Wepf, R. Wilson, T. Tenev, B. Lemaitre, M. Gstaiger, P. Meier, and F. Leulier PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling Cell Host Microbe 4 2008 147 158
27. M. McFall-Ngai, M.G. Hadfield, T.C. Bosch, H.V. Carey, T. Domazet-Lošo, A.E. Douglas, N. Dubilier, G. Eberl, T. Fukami, S.F. Gilbert, and et al. Animals in a bacterial world, a new imperative for the life sciences Proc. Natl. Acad. Sci. USA 110 2013 3229 3236
28. H. Myllymäki, S. Valanne, and M. Rämet The Drosophila imd signaling pathway J. Immunol. 192 2014 3455 3462
29. C. Neyen, M. Poidevin, A. Roussel, and B. Lemaitre Tissue- and ligand-specific sensing of gram-negative infection in drosophila by PGRP-LC isoforms and PGRP-LE J. Immunol. 189 2012 1886 1897
30. J.C. Paredes, D.P. Welchman, M. Poidevin, and B. Lemaitre Negative regulation by amidase PGRPs shapes the Drosophila antibacterial response and protects the fly from innocuous infection Immunity 35 2011 770 779
31. M.D. Phillips, and G.H. Thomas Brush border spectrin is required for early endosome recycling in Drosophila J. Cell Sci. 119 2006 1361 1370
32. C. Ren, P. Webster, S.E. Finkel, and J. Tower Increased internal and external bacterial load during Drosophila aging without life-span trade-off Cell Metab. 6 2007 144 152
33. J.H. Ryu, S.H. Kim, H.Y. Lee, J.Y. Bai, Y.D. Nam, J.W. Bae, D.G. Lee, S.C. Shin, E.M. Ha, and W.J. Lee Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in Drosophila Science 319 2008 777 782
34. C.A. Schneider, W.S. Rasband, and K.W. Eliceiri NIH Image to ImageJ: 25 years of image analysis Nat. Methods 9 2012 671 675
35. G. Sharon, D. Segal, J.M. Ringo, A. Hefetz, I. Zilber-Rosenberg, and E. Rosenberg Commensal bacteria play a role in mating preference of Drosophila melanogaster Proc. Natl. Acad. Sci. USA 107 2010 20051 20056
36. S.C. Shin, S.H. Kim, H. You, B. Kim, A.C. Kim, K.A. Lee, J.H. Yoon, J.H. Ryu, and W.J. Lee Drosophila microbiome modulates host developmental and metabolic homeostasis via insulin signaling Science 334 2011 670 674
37. M.M. Shirasu-Hiza, M.S. Dionne, L.N. Pham, J.S. Ayres, and D.S. Schneider Interactions between circadian rhythm and immunity in Drosophila melanogaster Curr. Biol. 17 2007 R353 R355
38. G. Storelli, A. Defaye, B. Erkosar, P. Hols, J. Royet, and F. Leulier Lactobacillus plantarum promotes Drosophila systemic growth by modulating hormonal signals through TOR-dependent nutrient sensing Cell Metab. 14 2011 403 414
39. A. Takehana, T. Yano, S. Mita, A. Kotani, Y. Oshima, and S. Kurata Peptidoglycan recognition protein (PGRP)-LE and PGRP-LC act synergistically in Drosophila immunity EMBO J. 23 2004 4690 4700
40. P. Tzou, S. Ohresser, D. Ferrandon, M. Capovilla, J.M. Reichhart, B. Lemaitre, J.A. Hoffmann, and J.L. Imler Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia Immunity 13 2000 737 748
41. I. Venu, Z. Durisko, J. Xu, and R. Dukas Social attraction mediated by fruit flies' microbiome J. Exp. Biol. 217 2014 1346 1352
42. A.C. Wong, A.J. Dobson, and A.E. Douglas Gut microbiota dictates the metabolic response of Drosophila to diet J. Exp. Biol. 217 2014 1894 1901
43. R. Yamada, S.A. Deshpande, K.D. Bruce, E.M. Mak, and W.W. Ja Microbes Promote Amino Acid Harvest to Rescue Undernutrition in Drosophila Cell Rep. 2015 10.1016/j.celrep.2015.01.018 Published online February 12, 2015