Mucoadhesion and mucosa-mimetic materials - A mini-review

International Journal of Pharmaceutics

Volumn 495, Issue 2, 2015, Pages 991-998

  Cook, Michael T ^a   Khutoryanskiy, Vitaliy V ^b  

^a UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

^b UNIVERSITY OF READING   (United Kingdom)

Author keywords

Biomimetic; Biomimicry; Mucoadhesive; Mucous; Mucus like; Topical drug delivery

Indexed keywords

2 HYDROXYPROPYL METHACRYLAMIDE; BENZENEBORONIC ACID; BIOMIMETIC MATERIAL; CARBOHYDRATE; COPOLYMER; EXCIPIENT; MUCIN; POLYMER; SALICYLHYDROXAMIC ACID; SULFATE; UNCLASSIFIED DRUG; DRUG; TISSUE ADHESIVE;

CHEMICAL INTERACTION; CHEMICAL REACTION; CULTURE TECHNIQUE; EX VIVO STUDY; HYDROGEL; HYDROGEN BOND; HYDROPHOBICITY; MUCOADHESION; MUCOSA; MUCUS; NONHUMAN; PLANT; PRIORITY JOURNAL; PROTEIN STRUCTURE; REVIEW; ANIMAL; BIOMIMETICS; CHEMISTRY; METABOLISM; PROCEDURES;

ANIMALS; BIOMIMETIC MATERIALS; BIOMIMETICS; EXCIPIENTS; MUCINS; MUCOUS MEMBRANE; PHARMACEUTICAL PREPARATIONS; TISSUE ADHESIVES;

EID: 84944145057     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.09.064     Document Type: Short Survey

References (60)

1. A. Allen, D.A. Hutton, and J.P. Pearson The MUC2 gene product: a human intestinal mucin Int. J. Biochem. Cell Biol. 30 1998 797 801
2. G.P. Andrews, T.P. Laverty, and D.S. Jones Mucoadhesive polymeric platforms for controlled drug delivery Eur. J. Pharm. Biopharm. 71 2009 505 518
3. R. Bansil, E. Stanley, and J. Lamont Mucin Biophysics. Annu. Rev. Physiol. 57 1995 635 657
4. R. Bansil, and B.S. Turner Mucin structure aggregation, physiological functions and biomedical applications Curr. Opin. Colloid Interface Sci. 11 2006 164 170
5. A. Bernkop-Schnürch, and A. Greimel Thiomers: the next generation of mucoadhesive polymers Am. J. Drug Deliv. 3 2005 141 154
6. M. Berry, R.B. Ellingham, and A.P. Corfield Polydispersity of normal human conjunctival mucins Invest. Ophthalmol. Vis. Sci. 37 1996 2559 2571
7. H. Blanco-Fuente, B. Vila-Dorrío, S. Anguiano-Igea, F.J. Otero-Espinar, and J. Blanco-Méndez Tanned leather: a good model for determining hydrogels bioadhesion Int. J. Pharm. 138 1996 103 112
8. M. Boegh, and H.M. Nielsen Mucus as a barrier to drug delivery - understanding and mimicking the barrier properties Basic Clin. Pharmacol. Toxicol. 116 2015 179 186
9. M. Bogataj, T. Vovk, M. Kerec, A. Dimnik, I. Grabnar, and A. Mrhar The correlation between zeta potential and mucoadhesion strength on pig vesical mucosa Biol. Pharm. Bull. 26 2003 743 746
10. S. Bonengel, and A. Bernkop-Schnürch Thiomers-from bench to market J. Control Release 195 2014 120 129
11. M. Brayman, A. Thathiah, and D.D. Carson MUC1: a multifunctional cell surface component of reproductive tissue epithelia Reprod. Biol. Endocrinol. 2 2004 4
12. B.J. Campbell Biochemical and functional aspects of mucus and mucin-type glycoproteins E. Mathiowitz, D.E. Chickering III C.-M. Lehr, Bioadhesive Drug Delivery Systems 1999 Dekker 85 130
13. H.K. Choi, O.J. Kim, C.K. Chung, and C.S. Cho A mucoadhesive polymer prepared by template polymerization of acrylic acid in the presence of poly(ethylene glycol) macromer J. Appl. Polym. Sci. 73 1999 2749 2754
14. M.T. Cook, S.A. Schmidt, E. Lee, W. Samprasit, P. Opanasopit, and V.V. Khutoryanskiy Synthesis of mucoadhesive thiol-bearing microgels from 2-(acetylthio) ethylacrylate and 2-hydroxyethylmethacrylate: novel drug delivery systems for chemotherapeutic agents to the bladder J. Mater. Chem. B 3 2015 6599 6604
15. M.T. Cook, S.L. Smith, and V. Khutoryanskiy Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing Chem. Commun. 51 2015 14447 14450 10.1039/C5CC02428E
16. J. Dekker, J.W. Rossen, H.A. Büller, and A.W.C. Einerhand The MUC family: an obituary Trends Biochem. Sci. 27 2002 126 131
17. L.M. Ensign, R. Cone, and J. Hanes Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers Adv. Drug Deliv. Rev. 64 2012 557 570
18. H.E. Friedl, S. Dünnhaupt, C. Waldner, and A. Bernkop-Schnürch Preactivated thiomers for vaginal drug delivery vehicles Biomaterials 34 2013 7811 7818
19. D.J. Hall, O.V. Khutoryanskaya, and V.V. Khutoryanskiy Developing synthetic mucosa-mimetic hydrogels to replace animal experimentation in characterisation of mucoadhesive drug delivery systems Soft Matter 7 2011 9620
20. R. Hamed, and J. Fiegel Synthetic tracheal mucus with native rheological and surface tension properties J. Biomed. Mater. Res. A 102 2014 1788 1798
21. E.E. Hassan, and J.M. Gallo A simple rheological method for the in vitro assessment of mucin-polymer bioadhesive bond strength Pharm. Res. 7 1990 491 495
22. P. Hobson-West What kind of animal is the three Rs? Altern. Lab. Anim. 37 Suppl. 2 2009 95 99
23. M. Hornof, W. Weyenberg, A. Ludwig, and A. Bernkop-Schnürch Mucoadhesive ocular insert based on thiolated poly(acrylic acid): development and in vivo evaluation in humans J. Control. Release 89 2003 419 428
24. J. Iqbal, G. Shahnaz, S. Dünnhaupt, C. Müller, F. Hintzen, and A. Bernkop-Schnürch Preactivated thiomers as mucoadhesive polymers for drug delivery Biomaterials 33 2012 1528 1535
25. G.S. Irmukhametova, G.A. Mun, and V.V. Khutoryanskiy Thiolated mucoadhesive and PEGylated nonmucoadhesive organosilica nanoparticles from 3-mercaptopropyltrimethoxysilane Langmuir 27 2011 9551 9556
26. E. Jabbari, N. Wisniewski, and N.A. Peppas Evidence of mucoadhesion by chain interpenetration at a poly (acrylic acid)/mucin interface using ATR-FTIR spectroscopy J. Control. Release. 26 1993 99 108
27. Y. Jacques, and P. Buri An investigation of the physical behaviour of moisture-activated mucoadhesive hydrogels upon contact with biological and non-biological substrates Pharm. Acta Helv. 72 1997 225 232
28. M.E.V. Johansson, D. Ambort, T. Pelaseyed, A. Schütte, J.K. Gustafsson, A. Ermund, D.B. Subramani, J.M. Holmén-Larsson, K. Thomsson, J.H. a Bergström, S. van der Post, A.M. Rodriguez-Piñeiro, H. Sjövall, M. Bäckström, and G.C. Hansson Composition and functional role of the mucus layers in the intestine Cell. Mol. Life Sci. 68 2011 3635 3641
29. S. Keely, A. Rullay, C. Wilson, A. Carmichael, S. Carrington, A. Corfield, D.M. Haddleton, and D.J. Brayden In vitro and ex vivo intestinal tissue models to measure mucoadhesion of poly (methacrylate) and N-trimethylated chitosan polymers Pharm. Res. 22 2005 38 49
30. O. Khutoryanskaya, M. Potgieter, and V.V. Khutoryanskiy Multilayered hydrogel coatings covalently-linked to glass surfaces showing a potential to mimic mucosal tissues Soft Matter 2010 551 557
31. V.V. Khutoryanskiy Advances in mucoadhesion and mucoadhesive polymers Macromol. Biosci. 11 2011 748 764
32. V.V. Khutoryanskiy Mucoadhesive Materials and Drug Delivery Systems 2014 John Wiley and Sons, Ltd. New York
33. A. Larhed, P. Artursson, and E. Björk The influence of intestinal mucus components on the diffusion of drugs Pharm. Res. 15 1998 66 71
34. A. Ludwig The use of mucoadhesive polymers in ocular drug delivery Adv. Drug Deliv. Rev. 57 2005 1595 1639
35. L. Maggi, E. Carena, M.L. Torre, P. Giunchedi, and U. Conte In vitro/ex vivo methods for the evaluation of bioadhesive polymers. A preliminary study STP Pharm. Sci. 4 1994 343 348
36. A. Mahalingam, J.I. Jay, K. Langheinrich, S. Shukair, M.D. McRaven, L.C. Rohan, B.C. Herold, T.J. Hope, and P.F. Kiser Inhibition of the transport of HIV in vitro using a pH-responsive synthetic mucin-like polymer system Biomaterials 32 2011 8343 8355
37. F. McInnes, A.J. Baillie, and H.N.E. Stevens The use of simple dynamic mucosal models and confocal microscopy for the evaluation of lyophilised nasal formulations J. Pharm. Pharmacol. 59 2007 759 767
38. B. Menchicchi, J.P. Fuenzalida, K.B. Bobbili, A. Hensel, M.J. Swamy, and F.M. Goycoolea Structure of chitosan determines its interactions with mucin Biomacromolecules 15 2014 3550 3558
39. D.M. Moncada, S.J. Kammanadiminti, and K. Chadee Mucin and toll-like receptors in host defense against intestinal parasites Trends Parasitol. 19 2003 305 311
40. S.A. Mortazavi, and J.D. Smart An investigation of some factors influencing the in vitro assessment of mucoadhesion Int. J. Pharm. 116 1995 223 230
41. S.A. Mortazavi An in vitro assessment of mucus / mucoadhesive interactions Int. J. Pharm. 124 1995 173 182
42. N.A. Nafee, F.A. Ismail, N.A. Boraie, and L.M. Mortada Mucoadhesive delivery systems. I. Evaluation of mucoadhesive polymers for buccal tablet formulation Drug Dev. Ind. Pharm. 30 2004 985 993
43. F. Nakamura, R. Ohta, Y. Machida, and T. Nagai In vitro and in vivo nasal mucoadhesion of some water-soluble polymers Int. J. Pharm. 134 1996 173 181
44. H. Park, and J.R. Robinson Mechanisms of mucoadhesion of poly(acrylic acid) hydrogels Pharm. Res. 4 1987 457 464
45. K. Park, and J.R. Robinson Bioadhesive polymers as platforms for oral-controlled drug delivery: method to study bioadhesion Int. J. Pharm. 19 1984 107 127
46. N.A. Peppas, and Y. Huang Nanoscale technology of mucoadhesive interactions Adv. Drug Deliv. Rev. 56 2004 1675 1687
47. J.J. Sahlin, and N.A. Peppas Enhanced hydrogel adhesion by polymer interdiffusion: use of linear poly(ethylene glycol) as an adhesion promoter J. Biomater. Sci. Polym. Ed. 8 1997 421 436
48. S. Sakuma, R. Sudo, N. Suzuki, H. Kikuchi, M. Akashi, and M. Hayashi Mucoadhesion of polystyrene nanoparticles having surface hydrophilic polymeric chains in the gastrointestinal tract Int. J. Pharm. 177 1999 161 172
49. A.H. Shojaei, J. Paulson, and S. Honary Evaluation of poly(acrylic acid-co-ethylhexyl acrylate) films for mucoadhesive transbuccal drug delivery: Factors affecting the force of mucoadhesion J. Control. Release 67 2000 223 232
50. H.H. Sigurdsson, J. Kirch, and C.-M. Lehr Mucus as a barrier to lipophilic drugs Int. J. Pharm. 453 2013 56 64
51. J.D. Smart The basics and underlying mechanisms of mucoadhesion Adv. Drug Deliv. Rev. 57 2005 1556 1568
52. I.A. Sogias, A.C. Williams, and V.V. Khutoryanskiy Why is chitosan mucoadhesive? Biomacromolecules 9 2008 1837 1842
53. A. Sosnik, J. das Neves, and B. Sarmento Mucoadhesive polymers in the design of nano-drug delivery systems for administration by non-parenteral routes: a review Prog. Polym. Sci. 39 2014 2030 2075
54. K. Takayama, M. Hirata, Y. Machida, T. Masada, T. Sannan, and T. Nagai Effect of interpolymer complex formation on bioadhesive property and drug release phenomenon of compressed tablet consisting of chitosan and sodium hyaluronate Chem. Pharm. Bull. 38 1990 1993 1997
55. C. Tang, A.F. Miller, and A. Saiani Peptide hydrogels as mucoadhesives for local drug delivery Int. J. Pharm. 465 2014 427 435
56. S.J. Teague, and A.M. Davis Hydrogen bonding hydrophobic interactions, and failure of the rigid receptor hypothesis Angew. Chem. Int. Ed. 38 1999 736 749
57. K. Thomsson, A. a Prakobphol, H. Leffler, M.S. Reddy, M.J. Levine, S.J. Fisher, and G.C. Hansson The salivary mucin MG1 (MUC5B) carries a repertoire of unique oligosaccharides that is large and diverse Glycobiology 12 2002 1 14
58. A. Urtti Challenges and obstacles of ocular pharmacokinetics and drug delivery Adv. Drug Deliv. Rev. 58 2006 1131 1135
59. C.A. Withers, M.T. Cook, L. Methven, M.A. Gosney, and V.V. Khutoryanskiy Investigation of milk proteins binding to the oral mucosa Food Funct. 4 2013 1668 1674
60. X. Zhu, J. Degraaf, F.M. Winnik, and D. Leckband pH-dependent mucoadhesion of a poly(N-isopropylacrylamide) copolymer reveals design rules for drug delivery Langmuir 20 2004 10648 10656