In vitro and ex vivo intestinal tissue models to measure mucoadhesion of poly (methacrylate) and N-trimethylated chitosan polymers

Pharmaceutical Research

Volumn 22, Issue 1, 2005, Pages 38-49

  Keely, Simon ^a   Rullay, Atvinder ^b   Wilson, Carolyn ^a   Carmichael, Adrian ^b,d   Carrington, Steve ^a   Corfield, Anthony ^c   Haddleton, David M ^b   Brayden, David J ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF WARWICK   (United Kingdom)

^c BRISTOL ROYAL INFIRMARY   (United Kingdom)

^d Vanguard Centre   (United Kingdom)

Author keywords

Chitosan; HT29 monolayers; Living radical polymerization; Methacrylate polymers; Mucoadhesion

Indexed keywords

ACETYLCYSTEINE; CHITOSAN; COUMARIN DERIVATIVE; DEXTRAN DERIVATIVE; LACTATE DEHYDROGENASE; METHYL IODIDE; MUCOLYTIC AGENT; POLYMER; POLYMETHACRYLIC ACID;

ARTICLE; CELL DIFFERENTIATION; CONFOCAL LASER MICROSCOPY; CYTOTOXICITY; DRUG PENETRATION; ELECTRIC RESISTANCE; EPITHELIUM; EX VIVO STUDY; FLUORESCENCE; FLUORESCENCE MICROSCOPY; IN VITRO STUDY; INTESTINE; MICROSCOPY; MUCUS SECRETION; PRIORITY JOURNAL;

ANIMALS; CHITOSAN; HT29 CELLS; HUMANS; INTESTINES; MODELS, BIOLOGICAL; POLYMERS; POLYMETHACRYLIC ACIDS; RATS; TISSUE ADHESIVES;

EID: 17644385834     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11095-004-9007-1     Document Type: Article

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