메뉴 건너뛰기




Volumn 24, Issue 20, 2015, Pages 5805-5827

Engrailed-2 (En2) deletion produces multiple neurodevelopmental defects in monoamine systems, forebrain structures and neurogenesis and behavior

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; DOPAMINE; EOMESODERMIN; NORADRENALIN; SEROTONIN; TRANSCRIPTION FACTOR SOX2; ENGRAILED 2 PROTEIN; HOMEODOMAIN PROTEIN; NERVE PROTEIN;

EID: 84943790821     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv301     Document Type: Article
Times cited : (44)

References (152)
  • 3
    • 84863980709 scopus 로고    scopus 로고
    • Genetic architectures of psychiatric disorders: the emerging picture and its implications.
    • Sullivan, P.F., Daly, M.J. and O'Donovan, M. (2012) Genetic architectures of psychiatric disorders: the emerging picture and its implications. Nat. Rev. Genet., 13, 537-551.
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 537-551
    • Sullivan, P.F.1    Daly, M.J.2    O'Donovan, M.3
  • 5
    • 3142523276 scopus 로고    scopus 로고
    • Association of the homeobox transcription factor, ENGRAILED 2, with autism spectrum disorder.
    • Gharani, N., Benayed, R., Mancuso, V., Brzustowicz, L.M. and Millonig, J.H. (2004) Association of the homeobox transcription factor, ENGRAILED 2, with autism spectrum disorder. Mol. Psychiatry, 9, 474-484.
    • (2004) Mol. Psychiatry , vol.9 , pp. 474-484
    • Gharani, N.1    Benayed, R.2    Mancuso, V.3    Brzustowicz, L.M.4    Millonig, J.H.5
  • 10
    • 45549104943 scopus 로고    scopus 로고
    • Association of the homeobox transcription factor gene ENGRAILED 2 with autistic disorder in Chinese children.
    • Yang, P., Lung, F.W., Jong, Y.J., Hsieh, H.Y., Liang, C.L. and Juo, S.H. (2008) Association of the homeobox transcription factor gene ENGRAILED 2 with autistic disorder in Chinese children. Neuropsychobiology, 57, 3-8.
    • (2008) Neuropsychobiology , vol.57 , pp. 3-8
    • Yang, P.1    Lung, F.W.2    Jong, Y.J.3    Hsieh, H.Y.4    Liang, C.L.5    Juo, S.H.6
  • 12
    • 84894619880 scopus 로고    scopus 로고
    • Autism associated gene, engrailed2, and flanking gene levels are altered in post-mortem cerebellum.
    • Choi, J., Ababon, M.R., Soliman, M., Lin, Y., Brzustowicz, L.M., Matteson, P.G. and Millonig, J.H. (2014) Autism associated gene, engrailed2, and flanking gene levels are altered in post-mortem cerebellum. PLoS One, 9, e87208.
    • (2014) PLoS One , vol.9 , pp. e87208
    • Choi, J.1    Ababon, M.R.2    Soliman, M.3    Lin, Y.4    Brzustowicz, L.M.5    Matteson, P.G.6    Millonig, J.H.7
  • 13
    • 84863261493 scopus 로고    scopus 로고
    • Cut-like homeobox 1 and nuclear factor I/B mediate ENGRAILED2 autism spectrum disorder-associated haplotype function.
    • Choi, J., Ababon, M.R., Matteson, P.G. and Millonig, J.H. (2012) Cut-like homeobox 1 and nuclear factor I/B mediate ENGRAILED2 autism spectrum disorder-associated haplotype function. Hum. Mol. Genet., 21, 1566-1580.
    • (2012) Hum. Mol. Genet. , vol.21 , pp. 1566-1580
    • Choi, J.1    Ababon, M.R.2    Matteson, P.G.3    Millonig, J.H.4
  • 14
    • 84874340720 scopus 로고    scopus 로고
    • Complex epigenetic regulation of engrailed-2 (EN-2) homeobox gene in the autism cerebellum.
    • James, S.J., Shpyleva, S., Melnyk, S., Pavliv, O. and Pogribny, I.P. (2013) Complex epigenetic regulation of engrailed-2 (EN-2) homeobox gene in the autism cerebellum. Transl. Psychiatry, 3, e232.
    • (2013) Transl. Psychiatry , vol.3 , pp. e232
    • James, S.J.1    Shpyleva, S.2    Melnyk, S.3    Pavliv, O.4    Pogribny, I.P.5
  • 15
    • 84991497733 scopus 로고    scopus 로고
    • Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum.
    • James, S.J., Shpyleva, S., Melnyk, S., Pavliv, O. and Pogribny, I.P. (2014) Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum. Transl. Psychiatry, 4, e460.
    • (2014) Transl. Psychiatry , vol.4 , pp. e460
    • James, S.J.1    Shpyleva, S.2    Melnyk, S.3    Pavliv, O.4    Pogribny, I.P.5
  • 16
    • 33749254952 scopus 로고    scopus 로고
    • En2 knockout mice display neurobehavioral and neurochemical alterations relevant to autism spectrum disorder.
    • Cheh, M.A., Millonig, J.H., Roselli, L.M., Ming, X., Jacobsen, E., Kamdar, S. and Wagner, G.C. (2006) En2 knockout mice display neurobehavioral and neurochemical alterations relevant to autism spectrum disorder. Brain Res., 1116, 166-176.
    • (2006) Brain Res. , vol.1116 , pp. 166-176
    • Cheh, M.A.1    Millonig, J.H.2    Roselli, L.M.3    Ming, X.4    Jacobsen, E.5    Kamdar, S.6    Wagner, G.C.7
  • 19
    • 0023968542 scopus 로고
    • Expression of the homeo box-containing gene En-2 delineates a specific region of the developing mouse brain.
    • Davis, C.A., Noble-Topham, S.E., Rossant, J. and Joyner, A.L. (1988) Expression of the homeo box-containing gene En-2 delineates a specific region of the developing mouse brain. Genes Dev., 2, 361-371.
    • (1988) Genes Dev. , vol.2 , pp. 361-371
    • Davis, C.A.1    Noble-Topham, S.E.2    Rossant, J.3    Joyner, A.L.4
  • 20
    • 0030785533 scopus 로고    scopus 로고
    • Expression of the homeobox-containing genes EN1 and EN2 inhuman fetal midgestational medulla and cerebellum.
    • Zec, N., Rowitch, D.H., Bitgood, M.J. and Kinney, H.C. (1997) Expression of the homeobox-containing genes EN1 and EN2 inhuman fetal midgestational medulla and cerebellum. J. Neuropathol. Exp. Neurol., 56, 236-242.
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 236-242
    • Zec, N.1    Rowitch, D.H.2    Bitgood, M.J.3    Kinney, H.C.4
  • 21
    • 0031675550 scopus 로고    scopus 로고
    • Drosophila engrailed can substitute for mouse Engrailed1 function in midhindbrain, but not limb development.
    • Hanks, M.C., Loomis, C.A., Harris, E., Tong, C.X., Anson-Cartwright, L., Auerbach, A. and Joyner, A. (1998) Drosophila engrailed can substitute for mouse Engrailed1 function in midhindbrain, but not limb development. Development, 125, 4521-4530.
    • (1998) Development , vol.125 , pp. 4521-4530
    • Hanks, M.C.1    Loomis, C.A.2    Harris, E.3    Tong, C.X.4    Anson-Cartwright, L.5    Auerbach, A.6    Joyner, A.7
  • 22
    • 0030069671 scopus 로고    scopus 로고
    • Engrailed, Wnt and Pax genes regulate midbrain-hindbrain development.
    • Joyner, A.L. (1996) Engrailed, Wnt and Pax genes regulate midbrain-hindbrain development. Trends Genet., 12, 15-20.
    • (1996) Trends Genet. , vol.12 , pp. 15-20
    • Joyner, A.L.1
  • 23
    • 0024227273 scopus 로고
    • Expression patterns of the homeo box-containing genes En-1 and En-2 and the protooncogene int-1 diverge during mouse development.
    • Davis, C.A. and Joyner, A.L. (1988) Expression patterns of the homeo box-containing genes En-1 and En-2 and the protooncogene int-1 diverge during mouse development. Genes Dev., 2, 1736-1744.
    • (1988) Genes Dev. , vol.2 , pp. 1736-1744
    • Davis, C.A.1    Joyner, A.L.2
  • 24
    • 0036634851 scopus 로고    scopus 로고
    • Specification of catecholaminergic and serotonergic neurons.
    • Goridis, C. and Rohrer, H. (2002) Specification of catecholaminergic and serotonergic neurons. Nat. Rev. Neurosci., 3, 531-541.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 531-541
    • Goridis, C.1    Rohrer, H.2
  • 25
  • 29
    • 84867120199 scopus 로고    scopus 로고
    • Serotonin in the modulation of neural plasticity and networks: implications for neurodevelopmental disorders.
    • Lesch, K.P. and Waider, J. (2012) Serotonin in the modulation of neural plasticity and networks: implications for neurodevelopmental disorders. Neuron, 76, 175-191.
    • (2012) Neuron , vol.76 , pp. 175-191
    • Lesch, K.P.1    Waider, J.2
  • 31
    • 65349094033 scopus 로고    scopus 로고
    • Drugs, biogenic amine targets and the developing brain.
    • Frederick, A.L. and Stanwood, G.D. (2009) Drugs, biogenic amine targets and the developing brain. Dev. Neurosci., 31, 7-22.
    • (2009) Dev. Neurosci. , vol.31 , pp. 7-22
    • Frederick, A.L.1    Stanwood, G.D.2
  • 32
    • 10644287785 scopus 로고    scopus 로고
    • Engrailed genes control developmental fate of serotonergic and noradrenergic neurons in mid- and hindbrain in a gene dose-dependent manner.
    • Simon, H.H., Scholz, C. and O'Leary, D.D. (2005) Engrailed genes control developmental fate of serotonergic and noradrenergic neurons in mid- and hindbrain in a gene dose-dependent manner. Mol. Cell Neurosci., 28, 96-105.
    • (2005) Mol. Cell Neurosci. , vol.28 , pp. 96-105
    • Simon, H.H.1    Scholz, C.2    O'Leary, D.D.3
  • 33
    • 0035341443 scopus 로고    scopus 로고
    • Fate of midbrain dopaminergic neurons controlled by the engrailed genes.
    • Simon, H.H., Saueressig, H., Wurst, W., Goulding, M.D. and O'Leary, D.D. (2001) Fate of midbrain dopaminergic neurons controlled by the engrailed genes. J. Neurosci., 21, 3126-3134.
    • (2001) J. Neurosci. , vol.21 , pp. 3126-3134
    • Simon, H.H.1    Saueressig, H.2    Wurst, W.3    Goulding, M.D.4    O'Leary, D.D.5
  • 34
    • 84861870862 scopus 로고    scopus 로고
    • Engrailed is required in maturing serotonin neurons to regulate the cytoarchitecture and survival of the dorsal raphe nucleus.
    • Fox, S.R. and Deneris, E.S. (2012) Engrailed is required in maturing serotonin neurons to regulate the cytoarchitecture and survival of the dorsal raphe nucleus. J. Neurosci., 32, 7832-7842.
    • (2012) J. Neurosci. , vol.32 , pp. 7832-7842
    • Fox, S.R.1    Deneris, E.S.2
  • 36
    • 64749085056 scopus 로고    scopus 로고
    • Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression.
    • Alavian, K.N., Sgado, P., Alberi, L., Subramaniam, S. and Simon, H.H. (2009) Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression. Neural. Dev., 4, 11.
    • (2009) Neural. Dev. , vol.4 , pp. 11
    • Alavian, K.N.1    Sgado, P.2    Alberi, L.3    Subramaniam, S.4    Simon, H.H.5
  • 38
    • 0028310311 scopus 로고
    • Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum.
    • Wurst, W., Auerbach, A.B. and Joyner, A.L. (1994) Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum. Development, 120, 2065-2075.
    • (1994) Development , vol.120 , pp. 2065-2075
    • Wurst, W.1    Auerbach, A.B.2    Joyner, A.L.3
  • 39
    • 0025884460 scopus 로고
    • Subtle cerebellar phenotype in mice homozygous for a targeted deletion of the En-2 homeobox.
    • Joyner, A.L., Herrup, K., Auerbach, B.A., Davis, C.A. and Rossant, J. (1991) Subtle cerebellar phenotype in mice homozygous for a targeted deletion of the En-2 homeobox. Science, 251, 1239-1243.
    • (1991) Science , vol.251 , pp. 1239-1243
    • Joyner, A.L.1    Herrup, K.2    Auerbach, B.A.3    Davis, C.A.4    Rossant, J.5
  • 40
    • 80455177222 scopus 로고    scopus 로고
    • Spatially restricted and developmentally dynamic expression of engrailed genes in multiple cerebellar cell types.
    • Wilson, S.L., Kalinovsky, A., Orvis, G.D. and Joyner, A.L. (2011) Spatially restricted and developmentally dynamic expression of engrailed genes in multiple cerebellar cell types. Cerebellum, 10, 356-372.
    • (2011) Cerebellum , vol.10 , pp. 356-372
    • Wilson, S.L.1    Kalinovsky, A.2    Orvis, G.D.3    Joyner, A.L.4
  • 42
    • 74349097700 scopus 로고    scopus 로고
    • The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum.
    • Cheng, Y., Sudarov, A., Szulc, K.U., Sgaier, S.K., Stephen, D., Turnbull, D.H. and Joyner, A.L. (2010) The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum. Development, 137, 519-529.
    • (2010) Development , vol.137 , pp. 519-529
    • Cheng, Y.1    Sudarov, A.2    Szulc, K.U.3    Sgaier, S.K.4    Stephen, D.5    Turnbull, D.H.6    Joyner, A.L.7
  • 43
    • 77955375508 scopus 로고    scopus 로고
    • Engrailed homeobox genes regulate establishment of the cerebellar afferent circuit map.
    • Sillitoe, R.V., Vogel, M.W. and Joyner, A.L. (2010) Engrailed homeobox genes regulate establishment of the cerebellar afferent circuit map. J. Neurosci., 30, 10015-10024.
    • (2010) J. Neurosci. , vol.30 , pp. 10015-10024
    • Sillitoe, R.V.1    Vogel, M.W.2    Joyner, A.L.3
  • 44
    • 84896730301 scopus 로고    scopus 로고
    • Engrailed2 modulates cerebellar granule neuron precursor proliferation, differentiation and insulin-like growth factor 1 signaling during postnatal development.
    • Rossman, I.T., Lin, L., Morgan, K.M., Digiovine, M., Van Buskirk, E.K., Kamdar, S., Millonig, J.H. and Dicicco-Bloom, E. (2014) Engrailed2 modulates cerebellar granule neuron precursor proliferation, differentiation and insulin-like growth factor 1 signaling during postnatal development. Mol. Autism., 5, 9.
    • (2014) Mol. Autism. , vol.5 , pp. 9
    • Rossman, I.T.1    Lin, L.2    Morgan, K.M.3    Digiovine, M.4    Van Buskirk, E.K.5    Kamdar, S.6    Millonig, J.H.7    Dicicco-Bloom, E.8
  • 45
  • 46
    • 2642519680 scopus 로고    scopus 로고
    • Dopamine, learning and motivation.
    • Wise, R.A. (2004) Dopamine, learning and motivation. Nat. Rev. Neurosci., 5, 483-494.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 483-494
    • Wise, R.A.1
  • 47
    • 60549092240 scopus 로고    scopus 로고
    • The locus coeruleus and noradrenergic modulation of cognition.
    • Sara, S.J. (2009) The locus coeruleus and noradrenergic modulation of cognition. Nat. Rev. Neurosci., 10, 211-223.
    • (2009) Nat. Rev. Neurosci. , vol.10 , pp. 211-223
    • Sara, S.J.1
  • 49
    • 84867280540 scopus 로고    scopus 로고
    • Treatment of neurodevelopmental disorders in adulthood.
    • Castren, E., Elgersma, Y., Maffei, L. and Hagerman, R. (2012) Treatment of neurodevelopmental disorders in adulthood. J. Neurosci., 32, 14074-14079.
    • (2012) J. Neurosci. , vol.32 , pp. 14074-14079
    • Castren, E.1    Elgersma, Y.2    Maffei, L.3    Hagerman, R.4
  • 50
    • 84937947058 scopus 로고    scopus 로고
    • Serotonin 1A and serotonin 4 receptors: essential mediators of the neurogenic and behavioral actions of antidepressants
    • pii: 1073858414561303. [Epub ahead of print]
    • Samuels, B.A., Mendez-David, I., Faye, C., David, S.A., Pierz, K.A., Gardier, A.M., Hen, R. and David, D.J. (2014) Serotonin 1A and serotonin 4 receptors: essential mediators of the neurogenic and behavioral actions of antidepressants. Neuroscientist, pii: 1073858414561303. [Epub ahead of print].
    • (2014) Neuroscientist
    • Samuels, B.A.1    Mendez-David, I.2    Faye, C.3    David, S.A.4    Pierz, K.A.5    Gardier, A.M.6    Hen, R.7    David, D.J.8
  • 51
    • 34548348778 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis in depression.
    • Sahay, A. and Hen, R. (2007) Adult hippocampal neurogenesis in depression. Nat. Neurosci., 10, 1110-1115.
    • (2007) Nat. Neurosci. , vol.10 , pp. 1110-1115
    • Sahay, A.1    Hen, R.2
  • 52
    • 84916205330 scopus 로고    scopus 로고
    • Neurogenesis as a new target for the development of antidepressant drugs.
    • Pascual-Brazo, J., Baekelandt, V. and Encinas, J.M. (2014) Neurogenesis as a new target for the development of antidepressant drugs. Curr. Pharm. Des., 20, 3763-3775.
    • (2014) Curr. Pharm. Des. , vol.20 , pp. 3763-3775
    • Pascual-Brazo, J.1    Baekelandt, V.2    Encinas, J.M.3
  • 53
    • 84867213664 scopus 로고    scopus 로고
    • Depression and hippocampal neurogenesis: a road to remission?
    • Eisch, A.J. and Petrik, D. (2012) Depression and hippocampal neurogenesis: a road to remission? Science, 338, 72-75.
    • (2012) Science , vol.338 , pp. 72-75
    • Eisch, A.J.1    Petrik, D.2
  • 55
    • 34548501079 scopus 로고    scopus 로고
    • Childhood and adolescent depression: why do children and adults respond differently to antidepressant drugs?
    • Bylund, D.B. and Reed, A.L. (2007) Childhood and adolescent depression: why do children and adults respond differently to antidepressant drugs? Neurochem. Int., 51, 246-253.
    • (2007) Neurochem. Int. , vol.51 , pp. 246-253
    • Bylund, D.B.1    Reed, A.L.2
  • 56
    • 79960439151 scopus 로고    scopus 로고
    • The age-dependent effects of selective serotonin reuptake inhibitors in humans and rodents: a review.
    • Olivier, J.D., Blom, T., Arentsen, T. and Homberg, J.R. (2011) The age-dependent effects of selective serotonin reuptake inhibitors in humans and rodents: a review. Prog. Neuropsychopharmacol. Biol. Psychiatry, 35, 1400-1408.
    • (2011) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.35 , pp. 1400-1408
    • Olivier, J.D.1    Blom, T.2    Arentsen, T.3    Homberg, J.R.4
  • 57
    • 56249132435 scopus 로고    scopus 로고
    • Blocking of beta-2 adrenergic receptors hastens recovery from hypoglycemia-associated social withdrawal.
    • Park,M.J.,Guest, C.B., Barnes,M.B.,Martin, J., Ahmad, U., York, J.M. and Freund, G.G. (2008) Blocking of beta-2 adrenergic receptors hastens recovery from hypoglycemia-associated social withdrawal. Psychoneuroendocrinology, 33, 1411-1418.
    • (2008) Psychoneuroendocrinology , vol.33 , pp. 1411-1418
    • Park, M.J.1    Guest, C.B.2    Barnes, M.B.3    Martin, J.4    Ahmad, U.5    York, J.M.6    Freund, G.G.7
  • 60
    • 0023728919 scopus 로고
    • Free serotonin in plasma: autistic children and their first-degree relatives.
    • Cook, E.H. Jr, Leventhal, B.L. and Freedman, D.X. (1988) Free serotonin in plasma: autistic children and their first-degree relatives. Biol. Psychiatry, 24, 488-491.
    • (1988) Biol. Psychiatry , vol.24 , pp. 488-491
    • Jr., C.E.H.1    Leventhal, B.L.2    Freedman, D.X.3
  • 62
    • 0032987647 scopus 로고    scopus 로고
    • Developmental changes in brain serotonin synthesis capacity in autistic and nonautistic children.
    • Chugani, D.C., Muzik, O., Behen, M., Rothermel, R., Janisse, J.J., Lee, J. and Chugani, H.T. (1999) Developmental changes in brain serotonin synthesis capacity in autistic and nonautistic children. Ann. Neurol., 45, 287-295.
    • (1999) Ann. Neurol. , vol.45 , pp. 287-295
    • Chugani, D.C.1    Muzik, O.2    Behen, M.3    Rothermel, R.4    Janisse, J.J.5    Lee, J.6    Chugani, H.T.7
  • 63
    • 0035891882 scopus 로고    scopus 로고
    • Serotonin and brain development:role in human developmental diseases.
    • Whitaker-Azmitia, P.M. (2001) Serotonin and brain development:role in human developmental diseases. Brain Res. Bull., 56, 479-485.
    • (2001) Brain Res. Bull. , vol.56 , pp. 479-485
    • Whitaker-Azmitia, P.M.1
  • 64
    • 33646057412 scopus 로고    scopus 로고
    • Neurochemical correlates of autistic disorder: a review of the literature.
    • Lam, K.S.,Aman, M.G. and Arnold, L.E. (2006) Neurochemical correlates of autistic disorder: a review of the literature. Res. Dev. Disabil., 27, 254-289.
    • (2006) Res. Dev. Disabil. , vol.27 , pp. 254-289
    • Lam, K.S.1    Aman, M.G.2    Arnold, L.E.3
  • 65
    • 0032819210 scopus 로고    scopus 로고
    • Lamina-specific alterations in the dopamine innervation of the prefrontal cortex in schizophrenic subjects.
    • Akil, M., Pierri, J.N., Whitehead, R.E., Edgar, C.L., Mohila, C., Sampson, A.R. and Lewis, D.A. (1999) Lamina-specific alterations in the dopamine innervation of the prefrontal cortex in schizophrenic subjects. Am. J. Psychiatry, 156, 1580-1589.
    • (1999) Am. J. Psychiatry , vol.156 , pp. 1580-1589
    • Akil, M.1    Pierri, J.N.2    Whitehead, R.E.3    Edgar, C.L.4    Mohila, C.5    Sampson, A.R.6    Lewis, D.A.7
  • 67
    • 29044444109 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase (COMT) genotypes and working memory: associations with differing cognitive operations.
    • Bruder, G.E., Keilp, J.G., Xu, H., Shikhman, M., Schori, E., Gorman, J.M. and Gilliam, T.C. (2005) Catechol-O-methyltransferase (COMT) genotypes and working memory: associations with differing cognitive operations. Biol. Psychiatry, 58, 901-907.
    • (2005) Biol. Psychiatry , vol.58 , pp. 901-907
    • Bruder, G.E.1    Keilp, J.G.2    Xu, H.3    Shikhman, M.4    Schori, E.5    Gorman, J.M.6    Gilliam, T.C.7
  • 68
    • 0030897317 scopus 로고    scopus 로고
    • Behavioral consequences of abnormal cortical development: insights into developmental disabilities.
    • Berger-Sweeney, J. and Hohmann, C.F. (1997) Behavioral consequences of abnormal cortical development: insights into developmental disabilities. Behav. Brain Res., 86, 121-142.
    • (1997) Behav. Brain Res. , vol.86 , pp. 121-142
    • Berger-Sweeney, J.1    Hohmann, C.F.2
  • 69
    • 33845296559 scopus 로고    scopus 로고
    • Modeling early cortical serotonergic deficits in autism.
    • Boylan, C.B., Blue, M.E. and Hohmann, C.F. (2007) Modeling early cortical serotonergic deficits in autism. Behav. Brain Res., 176, 94-108.
    • (2007) Behav. Brain Res. , vol.176 , pp. 94-108
    • Boylan, C.B.1    Blue, M.E.2    Hohmann, C.F.3
  • 70
    • 0345258497 scopus 로고    scopus 로고
    • The developmental role of serotonin: news from mouse molecular genetics.
    • Gaspar, P., Cases, O. and Maroteaux, L. (2003) The developmental role of serotonin: news from mouse molecular genetics. Nat. Rev. Neurosci., 4, 1002-1012.
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 1002-1012
    • Gaspar, P.1    Cases, O.2    Maroteaux, L.3
  • 71
    • 7544241660 scopus 로고    scopus 로고
    • Development of neurotransmitter systems during critical periods
    • Herlenius, E. and Lagercrantz, H. (2004) Development of neurotransmitter systems during critical periods. Exp. Neurol., 190 Suppl 1, S8-S21.
    • (2004) Exp. Neurol. , vol.190 , pp. S8-S21
    • Herlenius, E.1    Lagercrantz, H.2
  • 73
    • 78049525067 scopus 로고    scopus 로고
    • The lifetime trajectory of schizophrenia and the concept of neurodevelopment.
    • Andreasen, N.C. (2010) The lifetime trajectory of schizophrenia and the concept of neurodevelopment. Dialogues Clin. Neurosci., 12, 409-415.
    • (2010) Dialogues Clin. Neurosci. , vol.12 , pp. 409-415
    • Andreasen, N.C.1
  • 77
    • 0027333188 scopus 로고
    • Development of dopamine-beta-hydroxylase-positive fiber innervation of the rat hippocampus.
    • Moudy, A.M., Kunkel, D.D. and Schwartzkroin, P.A. (1993) Development of dopamine-beta-hydroxylase-positive fiber innervation of the rat hippocampus. Synapse, 15, 307-318.
    • (1993) Synapse , vol.15 , pp. 307-318
    • Moudy, A.M.1    Kunkel, D.D.2    Schwartzkroin, P.A.3
  • 81
    • 0020555603 scopus 로고
    • Nucleus locus ceruleus: new evidence of anatomical and physiological specificity.
    • Foote, S.L., Bloom, F.E. and Aston-Jones, G. (1983) Nucleus locus ceruleus: new evidence of anatomical and physiological specificity. Physiol. Rev., 63, 844-914.
    • (1983) Physiol. Rev. , vol.63 , pp. 844-914
    • Foote, S.L.1    Bloom, F.E.2    Aston-Jones, G.3
  • 82
    • 0024369311 scopus 로고
    • Quantified distribution of the noradrenaline innervation in the hippocampus of adult rat.
    • Oleskevich, S., Descarries, L. and Lacaille, J.C. (1989) Quantified distribution of the noradrenaline innervation in the hippocampus of adult rat. J. Neurosci., 9, 3803-3815.
    • (1989) J. Neurosci. , vol.9 , pp. 3803-3815
    • Oleskevich, S.1    Descarries, L.2    Lacaille, J.C.3
  • 83
    • 0034084644 scopus 로고    scopus 로고
    • Biogenic amine transporters:regulation in flux.
    • Blakely, R.D. and Bauman, A.L. (2000) Biogenic amine transporters:regulation in flux. Curr. Opin. Neurobiol., 10, 328-336.
    • (2000) Curr. Opin. Neurobiol. , vol.10 , pp. 328-336
    • Blakely, R.D.1    Bauman, A.L.2
  • 84
    • 0023010849 scopus 로고
    • Coexistence of galanin-like immunoreactivity with catecholamines, 5- hydroxytryptamine, GABA and neuropeptides in the rat CNS.
    • Melander, T., Hokfelt, T., Rokaeus, A., Cuello, A.C., Oertel, W.H., Verhofstad, A. and Goldstein, M. (1986) Coexistence of galanin-like immunoreactivity with catecholamines, 5- hydroxytryptamine, GABA and neuropeptides in the rat CNS. J. Neurosci., 6, 3640-3654.
    • (1986) J. Neurosci. , vol.6 , pp. 3640-3654
    • Melander, T.1    Hokfelt, T.2    Rokaeus, A.3    Cuello, A.C.4    Oertel, W.H.5    Verhofstad, A.6    Goldstein, M.7
  • 85
    • 11344278799 scopus 로고    scopus 로고
    • Morphogenetic and cellular movements that shape the mouse cerebellum; insights from genetic fate mapping.
    • Sgaier, S.K., Millet, S., Villanueva, M.P., Berenshteyn, F., Song, C. and Joyner, A.L. (2005) Morphogenetic and cellular movements that shape the mouse cerebellum; insights from genetic fate mapping. Neuron, 45, 27-40.
    • (2005) Neuron , vol.45 , pp. 27-40
    • Sgaier, S.K.1    Millet, S.2    Villanueva, M.P.3    Berenshteyn, F.4    Song, C.5    Joyner, A.L.6
  • 86
    • 0019786472 scopus 로고
    • Autonomic nerves in the mammalian choroid plexus and their influence on the formation of cerebrospinal fluid.
    • Lindvall, M. and Owman, C. (1981) Autonomic nerves in the mammalian choroid plexus and their influence on the formation of cerebrospinal fluid. J. Cereb. Blood Flow Metab., 1, 245-266.
    • (1981) J. Cereb. Blood Flow Metab. , vol.1 , pp. 245-266
    • Lindvall, M.1    Owman, C.2
  • 87
    • 84880477026 scopus 로고    scopus 로고
    • Functional neuroanatomy of the central noradrenergic system.
    • Szabadi, E. (2013) Functional neuroanatomy of the central noradrenergic system. J. Psychopharmacol., 27, 659-693.
    • (2013) J. Psychopharmacol. , vol.27 , pp. 659-693
    • Szabadi, E.1
  • 88
  • 89
    • 77952068994 scopus 로고    scopus 로고
    • Progressive noradrenergic deficits in the locus coeruleus of Mecp2 deficient mice.
    • Roux, J.C., Panayotis, N., Dura, E. and Villard, L. (2010) Progressive noradrenergic deficits in the locus coeruleus of Mecp2 deficient mice. J. Neurosci. Res., 88, 1500-1509.
    • (2010) J. Neurosci. Res. , vol.88 , pp. 1500-1509
    • Roux, J.C.1    Panayotis, N.2    Dura, E.3    Villard, L.4
  • 91
    • 33845209203 scopus 로고    scopus 로고
    • BrdU immunohistochemistry for studying adult neurogenesis: paradigms, pitfalls, limitations, and validation.
    • Taupin, P. (2007) BrdU immunohistochemistry for studying adult neurogenesis: paradigms, pitfalls, limitations, and validation. Brain Res. Rev., 53, 198-214.
    • (2007) Brain Res. Rev. , vol.53 , pp. 198-214
    • Taupin, P.1
  • 92
    • 0037143741 scopus 로고    scopus 로고
    • Newly generated neurons in the amygdala and adjoining cortex of adult primates.
    • Bernier, P.J., Bedard, A., Vinet, J., Levesque, M. and Parent, A. (2002) Newly generated neurons in the amygdala and adjoining cortex of adult primates. Proc. Natl. Acad. Sci. USA, 99, 11464-11469.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 11464-11469
    • Bernier, P.J.1    Bedard, A.2    Vinet, J.3    Levesque, M.4    Parent, A.5
  • 93
    • 79957858669 scopus 로고    scopus 로고
    • Immunohistological markers for proliferative events, gliogenesis, and neurogenesis within the adult hippocampus.
    • von Bohlen und Halbach, O. (2011) Immunohistological markers for proliferative events, gliogenesis, and neurogenesis within the adult hippocampus. Cell Tissue Res., 345, 1-19.
    • (2011) Cell Tissue Res. , vol.345 , pp. 1-19
    • von Bohlenund Halbach, O.1
  • 94
    • 33644507720 scopus 로고    scopus 로고
    • Adult neurogenesis and functional plasticity in neuronal circuits.
    • Lledo, P.M., Alonso, M. and Grubb, M.S. (2006) Adult neurogenesis and functional plasticity in neuronal circuits. Nat. Rev. Neurosci., 7, 179-193.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 179-193
    • Lledo, P.M.1    Alonso, M.2    Grubb, M.S.3
  • 99
    • 15544381006 scopus 로고    scopus 로고
    • Increased volume of the pigmented neurons in the locus coeruleus of schizophrenic subjects: a stereological study.
    • Marner, L., Soborg, C. and Pakkenberg, B. (2005) Increased volume of the pigmented neurons in the locus coeruleus of schizophrenic subjects: a stereological study. J. Psychiatr Res., 39, 337-345.
    • (2005) J. Psychiatr Res. , vol.39 , pp. 337-345
    • Marner, L.1    Soborg, C.2    Pakkenberg, B.3
  • 100
  • 101
    • 0030221467 scopus 로고    scopus 로고
    • Rostral optic tectum acquires caudal characteristics following ectopic engrailed expression.
    • Logan, C.,Wizenmann, A., Drescher, U., Monschau, B., Bonhoeffer, F. and Lumsden, A. (1996) Rostral optic tectum acquires caudal characteristics following ectopic engrailed expression. Curr. Biol., 6, 1006-1014.
    • (1996) Curr. Biol. , vol.6 , pp. 1006-1014
    • Logan, C.1    Wizenmann, A.2    Drescher, U.3    Monschau, B.4    Bonhoeffer, F.5    Lumsden, A.6
  • 102
    • 0030937599 scopus 로고    scopus 로고
    • En-2 regulates the expression of the ligands for Eph type tyrosine kinases in chick embryonic tectum.
    • Shigetani,Y., Funahashi, J.I. and Nakamura,H. (1997) En-2 regulates the expression of the ligands for Eph type tyrosine kinases in chick embryonic tectum. Neurosci. Res., 27, 211-217.
    • (1997) Neurosci. Res. , vol.27 , pp. 211-217
    • Shigetani, Y.1    Funahashi, J.I.2    Nakamura, H.3
  • 104
    • 25444432765 scopus 로고    scopus 로고
    • Norepinephrine protects cortical neurons against microglial-induced cell death.
    • Madrigal, J.L., Feinstein, D.L. and Dello Russo, C. (2005) Norepinephrine protects cortical neurons against microglial-induced cell death. J. Neurosci. Res., 81, 390-396.
    • (2005) J. Neurosci. Res. , vol.81 , pp. 390-396
    • Madrigal, J.L.1    Feinstein, D.L.2    Dello Russo, C.3
  • 105
    • 77949918047 scopus 로고    scopus 로고
    • Norepinephrine and nitric oxide promote cell survival signaling in hippocampal neurons.
    • Patel, N.J., Chen, M.J. and Russo-Neustadt, A.A. (2010) Norepinephrine and nitric oxide promote cell survival signaling in hippocampal neurons. Eur. J. Pharmacol., 633, 1-9.
    • (2010) Eur. J. Pharmacol. , vol.633 , pp. 1-9
    • Patel, N.J.1    Chen, M.J.2    Russo-Neustadt, A.A.3
  • 106
    • 78651082238 scopus 로고    scopus 로고
    • Oppositional effects of serotonin receptors 5-HT1a, 2, and 2c in the regulation of adult hippocampal neurogenesis.
    • Klempin, F., Babu, H., De Pietri Tonelli, D., Alarcon, E., Fabel, K. and Kempermann, G. (2010) Oppositional effects of serotonin receptors 5-HT1a, 2, and 2c in the regulation of adult hippocampal neurogenesis. Front Mol. Neurosci., 3, doi:10.3389/fnmol.2010.00014.
    • (2010) Front Mol. Neurosci. , vol.3
    • Klempin, F.1    Babu, H.2    De Pietri Tonelli, D.3    Alarcon, E.4    Fabel, K.5    Kempermann, G.6
  • 108
    • 84903382244 scopus 로고    scopus 로고
    • Opposing effects of alpha2- and beta-adrenergic receptor stimulation on quiescent neural precursor cell activity and adult hippocampal neurogenesis.
    • Jhaveri, D.J., Nanavaty, I., Prosper, B.W., Marathe, S., Husain, B.F., Kernie, S.G., Bartlett, P.F. and Vaidya, V.A. (2014) Opposing effects of alpha2- and beta-adrenergic receptor stimulation on quiescent neural precursor cell activity and adult hippocampal neurogenesis. PLoS One, 9, e98736.
    • (2014) PLoS One , vol.9 , pp. e98736
    • Jhaveri, D.J.1    Nanavaty, I.2    Prosper, B.W.3    Marathe, S.4    Husain, B.F.5    Kernie, S.G.6    Bartlett, P.F.7    Vaidya, V.A.8
  • 109
    • 64149099920 scopus 로고    scopus 로고
    • Alpha-1A adrenergic receptor activation increases inhibitory tone in CA1 hippocampus.
    • Hillman, K.L., Lei, S., Doze, V.A. and Porter, J.E. (2009) Alpha-1A adrenergic receptor activation increases inhibitory tone in CA1 hippocampus. Epilepsy Res., 84, 97-109.
    • (2009) Epilepsy Res. , vol.84 , pp. 97-109
    • Hillman, K.L.1    Lei, S.2    Doze, V.A.3    Porter, J.E.4
  • 111
    • 84857138766 scopus 로고    scopus 로고
    • Disrupted cortical connectivity theory as an explanatory model for autism spectrum disorders.
    • Kana, R.K., Libero, L.E. and Moore, M.S. (2011) Disrupted cortical connectivity theory as an explanatory model for autism spectrum disorders. Phys. Life Rev., 8, 410-437.
    • (2011) Phys. Life Rev. , vol.8 , pp. 410-437
    • Kana, R.K.1    Libero, L.E.2    Moore, M.S.3
  • 112
    • 33846921789 scopus 로고    scopus 로고
    • Autism spectrum disorders:developmental disconnection syndromes.
    • Geschwind, D.H. and Levitt, P. (2007) Autism spectrum disorders:developmental disconnection syndromes. Curr. Opin. Neurobiol., 17, 103-111.
    • (2007) Curr. Opin. Neurobiol. , vol.17 , pp. 103-111
    • Geschwind, D.H.1    Levitt, P.2
  • 114
    • 84926331948 scopus 로고    scopus 로고
    • Connectivity in context:emphasizing neurodevelopment in autism spectrum disorder.
    • McPartland, J.C. and Jeste, S.S. (2015) Connectivity in context:emphasizing neurodevelopment in autism spectrum disorder. Biol. Psychiatry, 77, 772-774.
    • (2015) Biol. Psychiatry , vol.77 , pp. 772-774
    • McPartland, J.C.1    Jeste, S.S.2
  • 115
    • 34249309863 scopus 로고    scopus 로고
    • Comorbid psychopathology with autism spectrum disorder in children: an overview.
    • Matson, J.L. and Nebel-Schwalm, M.S. (2007) Comorbid psychopathology with autism spectrum disorder in children: an overview. Res. Dev. Disabil., 28, 341-352.
    • (2007) Res. Dev. Disabil. , vol.28 , pp. 341-352
    • Matson, J.L.1    Nebel-Schwalm, M.S.2
  • 117
    • 84876004372 scopus 로고    scopus 로고
    • A sensitive period for GABAergic interneurons in the dentate gyrus in modulating sensorimotor gating.
    • Guo, N., Yoshizaki, K., Kimura, R., Suto, F., Yanagawa, Y. and Osumi, N. (2013) A sensitive period for GABAergic interneurons in the dentate gyrus in modulating sensorimotor gating. J. Neurosci., 33, 6691-6704.
    • (2013) J. Neurosci. , vol.33 , pp. 6691-6704
    • Guo, N.1    Yoshizaki, K.2    Kimura, R.3    Suto, F.4    Yanagawa, Y.5    Osumi, N.6
  • 118
    • 79952610907 scopus 로고    scopus 로고
    • Neurogenesis and affective disorders.
    • Samuels, B.A. and Hen, R. (2011) Neurogenesis and affective disorders. Eur. J. Neurosci., 33, 1152-1159.
    • (2011) Eur. J. Neurosci. , vol.33 , pp. 1152-1159
    • Samuels, B.A.1    Hen, R.2
  • 119
    • 41749113342 scopus 로고    scopus 로고
    • The contribution of failing adult hippocampal neurogenesis to psychiatric disorders.
    • Kempermann, G., Krebs, J. and Fabel, K. (2008) The contribution of failing adult hippocampal neurogenesis to psychiatric disorders. Curr. Opin. Psychiatry, 21, 290-295.
    • (2008) Curr. Opin. Psychiatry , vol.21 , pp. 290-295
    • Kempermann, G.1    Krebs, J.2    Fabel, K.3
  • 120
    • 80053644036 scopus 로고    scopus 로고
    • Affiliative behavior requires juvenile, but not adult neurogenesis.
    • Wei, L., Meaney, M.J.,Duman, R.S. and Kaffman, A. (2011) Affiliative behavior requires juvenile, but not adult neurogenesis. J Neurosci, 31, 14335-14345.
    • (2011) J Neurosci , vol.31 , pp. 14335-14345
    • Wei, L.1    Meaney, M.J.2    Duman, R.S.3    Kaffman, A.4
  • 123
    • 84860162767 scopus 로고    scopus 로고
    • Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis.
    • Amiri, A., Cho, W., Zhou, J., Birnbaum, S.G., Sinton, C.M., McKay, R.M. and Parada, L.F. (2012) Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis. J. Neurosci., 32, 5880-5890.
    • (2012) J. Neurosci. , vol.32 , pp. 5880-5890
    • Amiri, A.1    Cho, W.2    Zhou, J.3    Birnbaum, S.G.4    Sinton, C.M.5    McKay, R.M.6    Parada, L.F.7
  • 124
    • 81855173456 scopus 로고    scopus 로고
    • Tbx1: identification of a 22q11.2 gene as a risk factor for autism spectrum disorder in a mouse model.
    • Hiramoto, T., Kang, G., Suzuki, G., Satoh, Y., Kucherlapati, R., Watanabe, Y. and Hiroi, N. (2011) Tbx1: identification of a 22q11.2 gene as a risk factor for autism spectrum disorder in a mouse model. Hum. Mol. Genet., 20, 4775-4785.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 4775-4785
    • Hiramoto, T.1    Kang, G.2    Suzuki, G.3    Satoh, Y.4    Kucherlapati, R.5    Watanabe, Y.6    Hiroi, N.7
  • 125
    • 80055039885 scopus 로고    scopus 로고
    • MAOA, DBH, and SLC6A4 variants in CHARGE: a case-control study of autism spectrum disorders
    • Tassone, F., Qi, L., Zhang, W., Hansen, R.L., Pessah, I.N. and Hertz-Picciotto, I. (2011)MAOA, DBH, and SLC6A4 variants in CHARGE: a case-control study of autism spectrum disorders. Autism Res., 4, 250-261.
    • (2011) Autism Res. , vol.4 , pp. 250-261
    • Tassone, F.1    Qi, L.2    Zhang, W.3    Hansen, R.L.4    Pessah, I.N.5    Hertz-Picciotto, I.6
  • 126
    • 80053514306 scopus 로고    scopus 로고
    • Association study of monoamine oxidase A/B genes and schizophrenia in Han Chinese.
    • Wei, Y.L., Li, C.X., Li, S.B., Liu, Y. and Hu, L. (2011) Association study of monoamine oxidase A/B genes and schizophrenia in Han Chinese. Behav. Brain Funct., 7, 42.
    • (2011) Behav. Brain Funct. , vol.7 , pp. 42
    • Wei, Y.L.1    Li, C.X.2    Li, S.B.3    Liu, Y.4    Hu, L.5
  • 127
    • 84879365378 scopus 로고    scopus 로고
    • Intermediate phenotype analysis of patients, unaffected siblings, and healthy controls identifies VMAT2 as a candidate gene for psychotic disorder and neurocognition.
    • Simons, C.J. and vanWinkel, R. and Group. (2013) Intermediate phenotype analysis of patients, unaffected siblings, and healthy controls identifies VMAT2 as a candidate gene for psychotic disorder and neurocognition. Schizophr. Bull., 39, 848-856.
    • (2013) Schizophr. Bull. , vol.39 , pp. 848-856
    • Simons, C.J.1    vanWinkel, R.2
  • 128
    • 77449133090 scopus 로고    scopus 로고
    • Association of monoamine oxidase A (MAOA) polymorphisms and clinical subgroups of major depressive disorders in the Han Chinese population.
    • Huang, S.Y., Lin, M.T., Lin, W.W., Huang, C.C., Shy, M.J. and Lu, R.B. (2009) Association of monoamine oxidase A (MAOA) polymorphisms and clinical subgroups of major depressive disorders in the Han Chinese population. World J. Biol. Psychiatry, 10, 544-551.
    • (2009) World J. Biol. Psychiatry , vol.10 , pp. 544-551
    • Huang, S.Y.1    Lin, M.T.2    Lin, W.W.3    Huang, C.C.4    Shy, M.J.5    Lu, R.B.6
  • 129
    • 27744436005 scopus 로고    scopus 로고
    • Association study of a monoamine oxidase a gene promoter polymorphism with major depressive disorder and antidepressant response.
    • Yu, Y.W., Tsai, S.J., Hong, C.J., Chen, T.J., Chen, M.C. and Yang, C.W. (2005) Association study of a monoamine oxidase a gene promoter polymorphism with major depressive disorder and antidepressant response. Neuropsychopharmacology, 30, 1719-1723.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 1719-1723
    • Yu, Y.W.1    Tsai, S.J.2    Hong, C.J.3    Chen, T.J.4    Chen, M.C.5    Yang, C.W.6
  • 130
    • 0032822713 scopus 로고    scopus 로고
    • A functional polymorphism in the promoter region of monoamine oxidase-A gene and mood disorders.
    • Kunugi, H., Ishida, S., Kato, T., Tatsumi, M., Sakai, T., Hattori, M., Hirose, T. and Nanko, S. (1999) A functional polymorphism in the promoter region of monoamine oxidase-A gene and mood disorders. Mol. Psychiatry, 4, 393-395.
    • (1999) Mol. Psychiatry , vol.4 , pp. 393-395
    • Kunugi, H.1    Ishida, S.2    Kato, T.3    Tatsumi, M.4    Sakai, T.5    Hattori, M.6    Hirose, T.7    Nanko, S.8
  • 131
    • 78649896493 scopus 로고    scopus 로고
    • Histone modifications regulate the norepinephrine transporter gene.
    • Bayles, R., Baker, E., Eikelis, N., El-Osta, A. and Lambert, G. (2010) Histone modifications regulate the norepinephrine transporter gene. Cell Cycle, 9, 4600-4601.
    • (2010) Cell Cycle , vol.9 , pp. 4600-4601
    • Bayles, R.1    Baker, E.2    Eikelis, N.3    El-Osta, A.4    Lambert, G.5
  • 132
    • 0036259735 scopus 로고    scopus 로고
    • Alterations of amino acids and monoamine metabolism in male Fmr1 knockout mice: a putative animal model of the human fragile X mental retardation syndrome.
    • Gruss, M. and Braun, K. (2001) Alterations of amino acids and monoamine metabolism in male Fmr1 knockout mice: a putative animal model of the human fragile X mental retardation syndrome. Neural Plast., 8, 285-298.
    • (2001) Neural Plast. , vol.8 , pp. 285-298
    • Gruss, M.1    Braun, K.2
  • 133
    • 79955929639 scopus 로고    scopus 로고
    • Impairment of the tyrosine hydroxylase neuronal network in the orbitofrontal cortex of a genetically modified mouse model of schizophrenia.
    • Sekiguchi, H., Iritani, S., Habuchi, C., Torii, Y., Kuroda, K., Kaibuchi, K. and Ozaki, N. (2011) Impairment of the tyrosine hydroxylase neuronal network in the orbitofrontal cortex of a genetically modified mouse model of schizophrenia. Brain Res., 1392, 47-53.
    • (2011) Brain Res. , vol.1392 , pp. 47-53
    • Sekiguchi, H.1    Iritani, S.2    Habuchi, C.3    Torii, Y.4    Kuroda, K.5    Kaibuchi, K.6    Ozaki, N.7
  • 134
    • 34347258541 scopus 로고    scopus 로고
    • Altered neocortical cell density and layer thickness in serotonin transporter knockout mice: a quantitation study.
    • Altamura, C., Dell'Acqua, M.L., Moessner, R., Murphy, D.L., Lesch, K.P. and Persico, A.M. (2007) Altered neocortical cell density and layer thickness in serotonin transporter knockout mice: a quantitation study. Cereb. Cortex, 17, 1394-1401.
    • (2007) Cereb. Cortex , vol.17 , pp. 1394-1401
    • Altamura, C.1    Dell'Acqua, M.L.2    Moessner, R.3    Murphy, D.L.4    Lesch, K.P.5    Persico, A.M.6
  • 135
    • 14644437094 scopus 로고    scopus 로고
    • A question of balance: a proposal for new mouse models of autism.
    • Murcia, C.L., Gulden, F. and Herrup, K. (2005) A question of balance: a proposal for new mouse models of autism. Int. J. Dev. Neurosci., 23, 265-275.
    • (2005) Int. J. Dev. Neurosci. , vol.23 , pp. 265-275
    • Murcia, C.L.1    Gulden, F.2    Herrup, K.3
  • 136
    • 82655175804 scopus 로고    scopus 로고
    • Inter-regional brain communication and its disturbance in autism.
    • Schipul, S.E., Keller, T.A. and Just, M.A. (2011) Inter-regional brain communication and its disturbance in autism. Front Syst. Neurosci., 5, 10.
    • (2011) Front Syst. Neurosci. , vol.5 , pp. 10
    • Schipul, S.E.1    Keller, T.A.2    Just, M.A.3
  • 137
  • 138
    • 0037381980 scopus 로고    scopus 로고
    • The locus coeruleus- noradrenergic system: modulation of behavioral state and state-dependent cognitive processes.
    • Berridge, C.W. and Waterhouse, B.D. (2003) The locus coeruleus- noradrenergic system: modulation of behavioral state and state-dependent cognitive processes. Brain Res. Brain Res. Rev., 42, 33-84.
    • (2003) Brain Res. Brain Res. Rev. , vol.42 , pp. 33-84
    • Berridge, C.W.1    Waterhouse, B.D.2
  • 139
    • 84874939983 scopus 로고    scopus 로고
    • Sex differences in autism spectrum disorders.
    • Werling, D.M. and Geschwind, D.H. (2013) Sex differences in autism spectrum disorders. Curr. Opin. Neurol., 26, 146-153.
    • (2013) Curr. Opin. Neurol. , vol.26 , pp. 146-153
    • Werling, D.M.1    Geschwind, D.H.2
  • 145
    • 45249111182 scopus 로고    scopus 로고
    • Na(+)/H(+) exchanger inhibition modifies dopamine neurotransmission during normal and metabolic stress conditions.
    • Rocha, M.A., Crockett, D.P.,Wong, L.Y., Richardson, J.R. and Sonsalla, P.K. (2008) Na(+)/H(+) exchanger inhibition modifies dopamine neurotransmission during normal and metabolic stress conditions. J. Neurochem., 106, 231-243.
    • (2008) J. Neurochem. , vol.106 , pp. 231-243
    • Rocha, M.A.1    Crockett, D.P.2    Wong, L.Y.3    Richardson, J.R.4    Sonsalla, P.K.5
  • 146
    • 0031565270 scopus 로고    scopus 로고
    • In vivo vulnerability of dopamine neurons to inhibition of energy metabolism.
    • Zeevalk, G.D., Manzino, L., Hoppe, J. and Sonsalla, P. (1997) In vivo vulnerability of dopamine neurons to inhibition of energy metabolism. Eur. J. Pharmacol., 320, 111-119.
    • (1997) Eur. J. Pharmacol. , vol.320 , pp. 111-119
    • Zeevalk, G.D.1    Manzino, L.2    Hoppe, J.3    Sonsalla, P.4
  • 147
    • 58849125861 scopus 로고    scopus 로고
    • Insulin- like growth factor-1 promotes G(1)/S cell cycle progression through bidirectional regulation of cyclins and cyclindependent kinase inhibitors via the phosphatidylinositol 3-kinase/Akt pathway in developing rat cerebral cortex.
    • Mairet-Coello, G., Tury, A. and DiCicco-Bloom, E. (2009) Insulin- like growth factor-1 promotes G(1)/S cell cycle progression through bidirectional regulation of cyclins and cyclindependent kinase inhibitors via the phosphatidylinositol 3-kinase/Akt pathway in developing rat cerebral cortex. J. Neurosci., 29, 775-788.
    • (2009) J. Neurosci. , vol.29 , pp. 775-788
    • Mairet-Coello, G.1    Tury, A.2    DiCicco-Bloom, E.3
  • 148
    • 36248961154 scopus 로고    scopus 로고
    • Developmental mercury exposure elicits acute hippocampal cell death, reductions in neurogenesis, and severe learning deficits during puberty.
    • Falluel-Morel, A., Sokolowski, K., Sisti, H.M., Zhou, X., Shors, T.J. and Dicicco-Bloom, E. (2007) Developmental mercury exposure elicits acute hippocampal cell death, reductions in neurogenesis, and severe learning deficits during puberty. J. Neurochem., 103, 1968-1981.
    • (2007) J. Neurochem. , vol.103 , pp. 1968-1981
    • Falluel-Morel, A.1    Sokolowski, K.2    Sisti, H.M.3    Zhou, X.4    Shors, T.J.5    Dicicco-Bloom, E.6
  • 149
    • 0033565402 scopus 로고    scopus 로고
    • Stimulation of neonatal and adult brain neurogenesis by subcutaneous injection of basic fibroblast growth factor.
    • Wagner, J.P., Black, I.B. and DiCicco-Bloom, E. (1999) Stimulation of neonatal and adult brain neurogenesis by subcutaneous injection of basic fibroblast growth factor. J. Neurosci., 19, 6006-6016.
    • (1999) J. Neurosci. , vol.19 , pp. 6006-6016
    • Wagner, J.P.1    Black, I.B.2    DiCicco-Bloom, E.3
  • 150
    • 84886087366 scopus 로고    scopus 로고
    • Neural stem cell apoptosis after low-methylmercury exposures in postnatal hippocampus produce persistent cell loss and adolescent memory deficits.
    • Sokolowski, K., Obiorah, M., Robinson, K., McCandlish, E., Buckley, B. and DiCicco-Bloom, E. (2013) Neural stem cell apoptosis after low-methylmercury exposures in postnatal hippocampus produce persistent cell loss and adolescent memory deficits. Dev. Neurobiol., 73, 936-949.
    • (2013) Dev. Neurobiol. , vol.73 , pp. 936-949
    • Sokolowski, K.1    Obiorah, M.2    Robinson, K.3    McCandlish, E.4    Buckley, B.5    DiCicco-Bloom, E.6
  • 151
    • 0036460609 scopus 로고    scopus 로고
    • Hippocampal granule neuron production and population size are regulated by levels of bFGF.
    • Cheng, Y., Black, I.B. and DiCicco-Bloom, E. (2002) Hippocampal granule neuron production and population size are regulated by levels of bFGF. Eur. J. Neurosci., 15, 3-12.
    • (2002) Eur. J. Neurosci. , vol.15 , pp. 3-12
    • Cheng, Y.1    Black, I.B.2    DiCicco-Bloom, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.