Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision

Nature

Volumn 489, Issue 7414, 2012, Pages 150-154

  Song, Juan ^a   Zhong, Chun ^a   Bonaguidi, Michael A ^a   Sun, Gerald J ^a   Hsu, Derek ^a   Gu, Yan ^b   Meletis, Konstantinos ^c   Huang, Z Josh ^d   Ge, Shaoyu ^b   Enikolopov, Grigori ^d   Deisseroth, Karl ^e   Luscher, Bernhard ^f   Christian, Kimberly M ^a   Ming, Guo Li ^a   Song, Hongjun ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

^d Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^e Stanford University   (United States)

^f PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; GLUTAMATE DECARBOXYLASE 67; NESTIN; PARVALBUMIN; SOMATOSTATIN; VASOACTIVE INTESTINAL POLYPEPTIDE;

ADULT; BRAIN; NEUROLOGY; PEPTIDE; RODENT; SURVIVAL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL DIVISION; CELL FATE; CELL ISOLATION; CELL RENEWAL; CONTROLLED STUDY; DENTATE GYRUS; GENETIC ANALYSIS; GLIA CELL; HIPPOCAMPUS; INTERNEURON; MOUSE; NERVE CELL; NERVE CELL NETWORK; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SUBUNIT; STEM CELL NICHE;

ANIMALS; CELL LINEAGE; CELL PROLIFERATION; DENTATE GYRUS; FEMALE; GABA MODULATORS; GABA-A RECEPTOR AGONISTS; GABA-A RECEPTOR ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; INTERNEURONS; MALE; MICE; MICE, INBRED C57BL; NEURAL PATHWAYS; NEURAL STEM CELLS; NEUROGENESIS; NEUROGLIA; PARVALBUMINS; RECEPTORS, GABA-A; SIGNAL TRANSDUCTION; SOMATOSTATIN; STEM CELL NICHE; VASOACTIVE INTESTINAL PEPTIDE;

EID: 84865801305     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11306     Document Type: Article

References (29)

1. Zhao, C., Deng, W. & Gage, F. H. Mechanisms and functional implications of adult neurogenesis. Cell 132, 645-660 (2008). (Pubitemid 351253687)
2. Kriegstein, A. & Alvarez-Buylla, A. The glial nature of embryonic and adult neural stem cells. Annu. Rev. Neurosci. 32, 149-184 (2009).
3. Ming, G. L. & Song, H. Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron 70, 687-702 (2011).
4. Seri, B., Garcia-Verdugo, J. M., McEwen, B. S. & Alvarez-Buylla, A. Astrocytes give rise to new neurons in the adult mammalian hippocampus. J. Neurosci. 21, 7153-7160 (2001). (Pubitemid 32846963)
5. Lagace, D. C. et al. Dynamic contribution of nestin-expressing stem cells to adult neurogenesis. J. Neurosci. 27, 12623-12629 (2007). (Pubitemid 350127816)
6. Imayoshi, I. et al. Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain. Nature Neurosci. 11, 1153-1161 (2008).
7. Encinas, J. M. et al. Division-coupled astrocytic differentiation and age-related depletion ofneural stemcells in the adult hippocampus. Cell StemCell 8, 566-579 (2011).
8. Dranovsky, A. et al. Experience dictates stem cell fate in the adult hippocampus. Neuron 70, 908-923 (2011).
9. Bonaguidi, M. A. et al. In vivo clonal analysis reveals self-renewing andmultipotent adult neural stem cell characteristics. Cell 145, 1142-1155 (2011).
10. Encinas, J. M., Vaahtokari, A. & Enikolopov, G. Fluoxetine targets early progenitor cells in the adult brain. Proc. Natl Acad. Sci. USA 103, 8233-8238 (2006).
11. Farrant, M. & Nusser, Z. Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors. Nature Rev. Neurosci. 6, 215-229 (2005).
12. Bekkers, J. M. & Stevens, C. F. NMDA and non-NMDA receptors are co-localized at individual excitatory synapses in cultured rat hippocampus. Nature341, 230-233 (1989).
13. Caraiscos, V. B. et al. Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by a5 subunit-containing c-aminobutyric acid type A receptors. Proc. Natl Acad. Sci. USA 101, 3662-3667 (2004). (Pubitemid 38338251)
14. Jagasia, R. et al. GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus. J. Neurosci. 29, 7966-7977 (2009).
15. Freund, T. F. & Buzsaki, G. Interneurons of the hippocampus. Hippocampus 6, 347-470 (1996).
16. Taniguchi, H. et al. A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex. Neuron 71, 995-1013 (2011).
17. Cardin, J. A. et al. Driving fast-spiking cells induces gamma rhythm and controls sensory responses. Nature 459, 663-667 (2009).
18. Ibi, D. et al. Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice. J. Neurochem. 105, 921-932 (2008). (Pubitemid 351562741)
19. Andang, M. et al. Histone H2AX-dependent GABAA receptor regulation of stem cell proliferation. Nature 451, 460-464 (2008). (Pubitemid 351158886)
20. Fernando, R. N. et al. Cell cycle restriction by histone H2AX limits proliferation of adult neural stem cells. Proc. Natl Acad. Sci. USA 108, 5837-5842 (2011).
21. Lolova, I. & Davidoff, M. Age-related morphological and morphometrical changes in parvalbumin- and calbindin-immunoreactive neurons in the rat hippocampal formation. Mech. Ageing Dev. 66, 195-211 (1992).
22. Satoh, J., Tabira, T., Sano, M., Nakayama, H. & Tateishi, J. Parvalbuminimmunoreactive neurons in the human central nervous system are decreased in Alzheimer's disease. Acta Neuropathol. 81, 388-395 (1991).
23. Masiulis, I., Yun, S.&Eisch, A. J. Theinterestinginterplay between interneurons and adult hippocampal neurogenesis. Mol. Neurobiol. 44, 287-302 (2011).
24. Knable, M. B., Barci, B. M., Webster, M. J., Meador-Woodruff, J. & Torrey, E. F. Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. Mol. Psychiatry 9, 609-620 (2004).
25. Gonzalez-Burgos, G., Fish, K. N. & Lewis, D. A. GABA neuron alterations, cortical circuit dysfunction and cognitive deficits in schizophrenia. Neural Plast. 2011, 723184 (2011).
26. Andre, V., Marescaux, C., Nehlig, A. & Fritschy, J. M. Alterations of hippocampal GABAergic system contribute to development of spontaneous recurrent seizures in the rat lithium-pilocarpine model of temporal lobe epilepsy. Hippocampus 11, 452-468 (2001). (Pubitemid 32799013)
27. Schweizer, C. et al. The c2 subunit of GABAA receptors is required for maintenance of receptors at mature synapses. Mol. Cell. Neurosci. 24, 442-450 (2003). (Pubitemid 37311307)
28. Ge, S. et al. GABA regulates synaptic integration of newly generated neurons in the adult brain. Nature 439, 589-593 (2006). (Pubitemid 43185382)
29. Kim, J. Y. et al. DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212. Neuron 63, 761-773 (2009).