메뉴 건너뛰기




Volumn 70, Issue 11, 2013, Pages 1199-1205

Association of posttraumatic stress disorder with reduced in vivo norepinephrine transporter availability in the locus coeruleus

Author keywords

[No Author keywords available]

Indexed keywords

METHYLREBOXETINE C 11; NORADRENALIN TRANSPORTER; RADIOLIGAND; TRACER; UNCLASSIFIED DRUG;

EID: 84888039502     PISSN: 2168622X     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamapsychiatry.2013.399     Document Type: Article
Times cited : (106)

References (44)
  • 1
    • 84870469320 scopus 로고    scopus 로고
    • American Psychiatric Association (Fourth Edition, Text Revision).Washington, DC: American Psychiatric Press
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition, Text Revision).Washington, DC: American Psychiatric Press; 2000.
    • (2000) Diagnostic and Statistical Manual of Mental Disorders
  • 2
    • 84857142714 scopus 로고    scopus 로고
    • Support for a novel five-factor model of posttraumatic stress symptoms in three independent samples of Iraq/Afghanistan veterans: A confirmatory factor analytic study
    • Pietrzak RH, Tsai J, Harpaz-Rotem I, Whealin JM, Southwick SM. Support for a novel five-factor model of posttraumatic stress symptoms in three independent samples of Iraq/Afghanistan veterans: a confirmatory factor analytic study. J Psychiatr Res. 2012;46(3):317-322.
    • (2012) J Psychiatr Res , vol.46 , Issue.3 , pp. 317-322
    • Pietrzak, R.H.1    Tsai, J.2    Harpaz-Rotem, I.3    Whealin, J.M.4    Southwick, S.M.5
  • 3
    • 84856235547 scopus 로고    scopus 로고
    • Assessing a five factor model of PTSD: Is dysphoric arousal a unique PTSD construct showing differential relationships with anxiety and depression?
    • Armour C, Elhai JD, Richardson D, Ractliffe K, Wang L, Elklit A. Assessing a five factor model of PTSD: is dysphoric arousal a unique PTSD construct showing differential relationships with anxiety and depression? J Anxiety Disord. 2012;26(2):368-376.
    • (2012) J Anxiety Disord , vol.26 , Issue.2 , pp. 368-376
    • Armour, C.1    Elhai, J.D.2    Richardson, D.3    Ractliffe, K.4    Wang, L.5    Elklit, A.6
  • 5
    • 84871056056 scopus 로고    scopus 로고
    • Assessing the fit of the dysphoric arousal model across two nationally representative epidemiological surveys: The Australian NSMHWB and the United States NESARC
    • Armour C, Carragher N, Elhai JD. Assessing the fit of the dysphoric arousal model across two nationally representative epidemiological surveys: the Australian NSMHWB and the United States NESARC. J Anxiety Disord. 2013;27(1):109-115.
    • (2013) J Anxiety Disord , vol.27 , Issue.1 , pp. 109-115
    • Armour, C.1    Carragher, N.2    Elhai, J.D.3
  • 6
    • 84884211317 scopus 로고    scopus 로고
    • Linking in vivo brain serotonin type 1B receptor density to phenotypic heterogeneity of posttraumatic stress symptomatology
    • Pietrzak RH, Henry S, Southwick SM, Krystal JH, Neumeister A. Linking in vivo brain serotonin type 1B receptor density to phenotypic heterogeneity of posttraumatic stress symptomatology. Mol Psychiatry. 2013;18(4):399-401.
    • (2013) Mol Psychiatry , vol.18 , Issue.4 , pp. 399-401
    • Pietrzak, R.H.1    Henry, S.2    Southwick, S.M.3    Krystal, J.H.4    Neumeister, A.5
  • 7
    • 0027446493 scopus 로고
    • Neurotransmitter transporters: Recent progress
    • Amara SG, Kuhar MJ. Neurotransmitter transporters: recent progress. Annu Rev Neurosci. 1993;16:73-93.
    • (1993) Annu Rev Neurosci , vol.16 , pp. 73-93
    • Amara, S.G.1    Kuhar, M.J.2
  • 8
    • 0031054886 scopus 로고    scopus 로고
    • Pharmacology and distribution of norepinephrine transporters in the human locus coeruleus and raphe nuclei
    • Ordway GA, Stockmeier CA, Cason GW, Klimek V. Pharmacology and distribution of norepinephrine transporters in the human locus coeruleus and raphe nuclei. J Neurosci. 1997;17(5):1710-1719.
    • (1997) J Neurosci , vol.17 , Issue.5 , pp. 1710-1719
    • Ordway, G.A.1    Stockmeier, C.A.2    Cason, G.W.3    Klimek, V.4
  • 9
    • 21444458653 scopus 로고    scopus 로고
    • Substrate binding stoichiometry and kinetics of the norepinephrine transporter
    • Schwartz JW, Novarino G, Piston DW, DeFelice LJ. Substrate binding stoichiometry and kinetics of the norepinephrine transporter. J Biol Chem. 2005;280(19):19177-19184.
    • (2005) J Biol Chem , vol.280 , Issue.19 , pp. 19177-19184
    • Schwartz, J.W.1    Novarino, G.2    Piston, D.W.3    DeFelice, L.J.4
  • 10
    • 0037264650 scopus 로고    scopus 로고
    • Plasma membrane monoamine transporters: Structure, regulation and function
    • Torres GE, Gainetdinov RR, Caron MG. Plasma membrane monoamine transporters: structure, regulation and function. Nat Rev Neurosci. 2003;4(1):13-25.
    • (2003) Nat Rev Neurosci , vol.4 , Issue.1 , pp. 13-25
    • Torres, G.E.1    Gainetdinov, R.R.2    Caron, M.G.3
  • 11
    • 0030842589 scopus 로고    scopus 로고
    • Effect of acute or repeated stress on behavior and brain norepinephrine system inWistar-Kyoto (WKY) rats
    • Zafar HM, Paré WP, Tejani-Butt SM. Effect of acute or repeated stress on behavior and brain norepinephrine system inWistar-Kyoto (WKY) rats. Brain Res Bull. 1997;44(3):289-295.
    • (1997) Brain Res Bull , vol.44 , Issue.3 , pp. 289-295
    • Zafar, H.M.1    Paré, W.P.2    Tejani-Butt, S.M.3
  • 12
    • 0037080158 scopus 로고    scopus 로고
    • Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: Evidence from knock-out mouse lines
    • Morón JA, Brockington A, Wise RA, Rocha BA, Hope BT. Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: evidence from knock-out mouse lines. J Neurosci. 2002;22(2):389-395.
    • (2002) J Neurosci , vol.22 , Issue.2 , pp. 389-395
    • Morón, J.A.1    Brockington, A.2    Wise, R.A.3    Rocha, B.A.4    Hope, B.T.5
  • 13
    • 2342651488 scopus 로고    scopus 로고
    • Ultrastructural interactions between terminals expressing the norepinephrine transporter and dopamine neurons in the rat and monkey ventral tegmental area
    • Liprando LA,Miner LH, Blakely RD, Lewis DA, Sesack SR. Ultrastructural interactions between terminals expressing the norepinephrine transporter and dopamine neurons in the rat and monkey ventral tegmental area. Synapse. 2004;52(4):233-244.
    • (2004) Synapse , vol.52 , Issue.4 , pp. 233-244
    • Liprando, L.A.1    Miner, L.H.2    Blakely, R.D.3    Lewis, D.A.4    Sesack, S.R.5
  • 14
    • 32544452050 scopus 로고    scopus 로고
    • Chronic stress increases the plasmalemmal distribution of the norepinephrine transporter and the coexpression of tyrosine hydroxylase in norepinephrine axons in the prefrontal cortex
    • Miner LH, Jedema HP, Moore FW, Blakely RD, Grace AA, Sesack SR. Chronic stress increases the plasmalemmal distribution of the norepinephrine transporter and the coexpression of tyrosine hydroxylase in norepinephrine axons in the prefrontal cortex. J Neurosci. 2006;26(5):1571-1578.
    • (2006) J Neurosci , vol.26 , Issue.5 , pp. 1571-1578
    • Miner, L.H.1    Jedema, H.P.2    Moore, F.W.3    Blakely, R.D.4    Grace, A.A.5    Sesack, S.R.6
  • 15
    • 20444425251 scopus 로고    scopus 로고
    • Neurobiology of executive functions: Catecholamine influences on prefrontal cortical functions
    • Arnsten AF, Li BM. Neurobiology of executive functions: catecholamine influences on prefrontal cortical functions. Biol Psychiatry. 2005;57(11):1377-1384.
    • (2005) Biol Psychiatry , vol.57 , Issue.11 , pp. 1377-1384
    • Arnsten, A.F.1    Li, B.M.2
  • 16
    • 20744446933 scopus 로고    scopus 로고
    • Modeling and analysis of PET studies with norepinephrine transporter ligands: The search for a reference region
    • Logan J, Ding YS, Lin KS, Pareto D, Fowler J, Biegon A. Modeling and analysis of PET studies with norepinephrine transporter ligands: the search for a reference region. Nucl Med Biol. 2005;32(5):531-542.
    • (2005) Nucl Med Biol , vol.32 , Issue.5 , pp. 531-542
    • Logan, J.1    Ding, Y.S.2    Lin, K.S.3    Pareto, D.4    Fowler, J.5    Biegon, A.6
  • 17
    • 34547851802 scopus 로고    scopus 로고
    • Imaging the norepinephrine transporter in humans with (S,S)-[ 11C]O-methyl reboxetine and PET: Problems and progress
    • Logan J,Wang GJ, Telang F, et al. Imaging the norepinephrine transporter in humans with (S,S)-[11C]O-methyl reboxetine and PET: problems and progress. Nucl Med Biol. 2007;34(6):667-679.
    • (2007) Nucl Med Biol , vol.34 , Issue.6 , pp. 667-679
    • Logan, J.1    Wang, G.J.2    Telang, F.3
  • 18
    • 0242653791 scopus 로고    scopus 로고
    • Evaluation of a new norepinephrine transporter PET ligand in baboons, both in brain and peripheral organs
    • Ding YS, Lin KS, Garza V, et al. Evaluation of a new norepinephrine transporter PET ligand in baboons, both in brain and peripheral organs. Synapse. 2003;50(4):345-352.
    • (2003) Synapse , vol.50 , Issue.4 , pp. 345-352
    • Ding, Y.S.1    Lin, K.S.2    Garza, V.3
  • 19
    • 22244464188 scopus 로고    scopus 로고
    • Comparative evaluation of positron emission tomography radiotracers for imaging the norepinephrine transporter: (S,S) and (R,R) enantiomers of reboxetine analogs ([11C]methylreboxetine, 3-Cl-[11C] methylreboxetine and [18F]fluororeboxetine), (R)-[ 11C]nisoxetine, [11C]oxaprotiline and [ 11C]lortalamine
    • Ding YS, Lin KS, Logan J, Benveniste H, Carter P. Comparative evaluation of positron emission tomography radiotracers for imaging the norepinephrine transporter: (S,S) and (R,R) enantiomers of reboxetine analogs ([ 11C]methylreboxetine, 3-Cl-[11C]methylreboxetine and [18F]fluororeboxetine), (R)-[11C]nisoxetine, [ 11C]oxaprotiline and [11C]lortalamine. J Neurochem. 2005;94(2):337-351.
    • (2005) J Neurochem , vol.94 , Issue.2 , pp. 337-351
    • Ding, Y.S.1    Lin, K.S.2    Logan, J.3    Benveniste, H.4    Carter, P.5
  • 20
    • 84861054500 scopus 로고    scopus 로고
    • Accessed August 5, 2013
    • National Center for Biotechnology Information. Molecular Imaging and Contrast Agent Database (MICAD). 2004-2013. www.ncbi.nlm.nih.gov/books/NBK5330/. Accessed August 5, 2013.
    • (2004) Molecular Imaging and Contrast Agent Database (MICAD)
  • 21
    • 15244360828 scopus 로고    scopus 로고
    • Specific in vitro binding of (S,S)-[3H]MeNER to norepinephrine transporters
    • Ghose S, Fujita M, Morrison P, et al. Specific in vitro binding of (S,S)-[3H]MeNER to norepinephrine transporters. Synapse. 2005;56(2):100-104.
    • (2005) Synapse , vol.56 , Issue.2 , pp. 100-104
    • Ghose, S.1    Fujita, M.2    Morrison, P.3
  • 22
    • 79953045711 scopus 로고    scopus 로고
    • Evaluation of [11C]MRB for assessment of occupancy of norepinephrine transporters: Studies with atomoxetine in non-human primates
    • Gallezot JD,Weinzimmer D, Nabulsi N, et al. Evaluation of [ 11C]MRB for assessment of occupancy of norepinephrine transporters: studies with atomoxetine in non-human primates. Neuroimage. 2011;56(1):268-279.
    • (2011) Neuroimage , vol.56 , Issue.1 , pp. 268-279
    • Gallezot, J.D.1    Weinzimmer, D.2    Nabulsi, N.3
  • 23
    • 77957899507 scopus 로고    scopus 로고
    • Clinically relevant doses ofmethylphenidate significantly occupy norepinephrine transporters in humans in vivo
    • Hannestad J, Gallezot JD, Planeta-Wilson B, et al. Clinically relevant doses ofmethylphenidate significantly occupy norepinephrine transporters in humans in vivo. Biol Psychiatry. 2010;68(9):854-860.
    • (2010) Biol Psychiatry , vol.68 , Issue.9 , pp. 854-860
    • Hannestad, J.1    Gallezot, J.D.2    Planeta-Wilson, B.3
  • 24
    • 0033820476 scopus 로고    scopus 로고
    • Development and preliminary validation of a brief broad-spectrum measure of trauma exposure: The Traumatic Life Events Questionnaire
    • Kubany ES, Haynes SN, Leisen MB, et al. Development and preliminary validation of a brief broad-spectrum measure of trauma exposure: the Traumatic Life Events Questionnaire. Psychol Assess. 2000;12(2):210-224.
    • (2000) Psychol Assess , vol.12 , Issue.2 , pp. 210-224
    • Kubany, E.S.1    Haynes, S.N.2    Leisen, M.B.3
  • 25
    • 0028833989 scopus 로고
    • The development of a Clinician-Administered PTSD Scale
    • Blake DD,Weathers FW, Nagy LM, et al. The development of a Clinician-Administered PTSD Scale. J Trauma Stress. 1995;8(1):75-90.
    • (1995) J Trauma Stress , vol.8 , Issue.1 , pp. 75-90
    • Blake, D.D.1    Weathers, F.W.2    Nagy, L.M.3
  • 26
    • 51549099524 scopus 로고
    • The assessment of anxiety states by rating
    • Hamilton M. The assessment of anxiety states by rating. Br J Med Psychol. 1959;32(1):50-55.
    • (1959) Br J Med Psychol , vol.32 , Issue.1 , pp. 50-55
    • Hamilton, M.1
  • 27
    • 0018425438 scopus 로고
    • A new depression scale designed to be sensitive to change
    • Montgomery SA, AsbergM. A new depression scale designed to be sensitive to change. Br J Psychiatry. 1979;134:382-389.
    • (1979) Br J Psychiatry , vol.134 , pp. 382-389
    • Montgomery, S.A.1    Asberg, M.2
  • 28
    • 0025923219 scopus 로고
    • The Fagerström Test for Nicotine Dependence: A revision of the Fagerström Tolerance Questionnaire
    • Heatherton TF, Kozlowski LT, Frecker RC, Fagerström KO. The Fagerström Test for Nicotine Dependence: a revision of the Fagerström Tolerance Questionnaire. Br J Addict. 1991;86(9):1119-1127.
    • (1991) Br J Addict , vol.86 , Issue.9 , pp. 1119-1127
    • Heatherton, T.F.1    Kozlowski, L.T.2    Frecker, R.C.3    Fagerström, K.O.4
  • 30
    • 34247203132 scopus 로고    scopus 로고
    • Performance evaluation of the ECAT HRRT: An LSO-LYSO double layer high resolution, high sensitivity scanner
    • de Jong HW, van Velden FH, Kloet RW, Buijs FL, Boellaard R, Lammertsma AA. Performance evaluation of the ECAT HRRT: an LSO-LYSO double layer high resolution, high sensitivity scanner. Phys Med Biol. 2007;52(5):1505-1526.
    • (2007) Phys Med Biol , vol.52 , Issue.5 , pp. 1505-1526
    • De Jong, H.W.1    Van Velden, F.H.2    Kloet, R.W.3    Buijs, F.L.4    Boellaard, R.5    Lammertsma, A.A.6
  • 31
    • 0028276642 scopus 로고
    • Fewer pigmented neurons in the locus coeruleus of uncomplicated alcoholics
    • Arango V, Underwood MD, Mann JJ. Fewer pigmented neurons in the locus coeruleus of uncomplicated alcoholics. Brain Res. 1994;650(1):1-8.
    • (1994) Brain Res , vol.650 , Issue.1 , pp. 1-8
    • Arango, V.1    Underwood, M.D.2    Mann, J.J.3
  • 32
    • 72449194762 scopus 로고    scopus 로고
    • PET imaging of the effects of age and cocaine on the norepinephrine transporter in the human brain using (S,S)-[11C]O-methylreboxetine and HRRT
    • Ding YS, Singhal T, Planeta-Wilson B, et al. PET imaging of the effects of age and cocaine on the norepinephrine transporter in the human brain using (S,S)-[11C]O-methylreboxetine and HRRT. Synapse. 2010;64(1):30-38.
    • (2010) Synapse , vol.64 , Issue.1 , pp. 30-38
    • Ding, Y.S.1    Singhal, T.2    Planeta-Wilson, B.3
  • 33
    • 0032081266 scopus 로고    scopus 로고
    • Design and construction of a realistic digital brain phantom
    • Collins DL, Zijdenbos AP, Kollokian V, et al. Design and construction of a realistic digital brain phantom. IEEE Trans Med Imaging. 1998;17(3):463-468.
    • (1998) IEEE Trans Med Imaging , vol.17 , Issue.3 , pp. 463-468
    • Collins, D.L.1    Zijdenbos, A.P.2    Kollokian, V.3
  • 34
    • 0036322886 scopus 로고    scopus 로고
    • Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain
    • Tzourio-Mazoyer N, Landeau B, Papathanassiou D, et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage. 2002;15(1):273-289.
    • (2002) Neuroimage , vol.15 , Issue.1 , pp. 273-289
    • Tzourio-Mazoyer, N.1    Landeau, B.2    Papathanassiou, D.3
  • 35
    • 0041335224 scopus 로고    scopus 로고
    • Linearized reference tissue parametric imagingmethods: Application to [11C]DASB positron emission tomography studies of the serotonin transporter in human brain
    • Ichise M, Liow JS, Lu JQ, et al. Linearized reference tissue parametric imagingmethods: application to [11C]DASB positron emission tomography studies of the serotonin transporter in human brain. J Cereb Blood Flow Metab. 2003;23(9):1096-1112.
    • (2003) J Cereb Blood Flow Metab , vol.23 , Issue.9 , pp. 1096-1112
    • Ichise, M.1    Liow, J.S.2    Lu, J.Q.3
  • 36
    • 0036792015 scopus 로고    scopus 로고
    • Strategies to improve neuroreceptor parameter estimation by linear regression analysis
    • Ichise M, Toyama H, Innis RB, Carson RE. Strategies to improve neuroreceptor parameter estimation by linear regression analysis. J Cereb Blood Flow Metab. 2002;22(10):1271-1281.
    • (2002) J Cereb Blood Flow Metab , vol.22 , Issue.10 , pp. 1271-1281
    • Ichise, M.1    Toyama, H.2    Innis, R.B.3    Carson, R.E.4
  • 38
    • 0035957794 scopus 로고    scopus 로고
    • Effect of novel stressors on gene expression of tyrosine hydroxylase and monoamine transporters in brainstem noradrenergic neurons of long-term repeatedly immobilized rats
    • Rusnák M, Kvetnanský R, Jeloková J, Palkovits M. Effect of novel stressors on gene expression of tyrosine hydroxylase and monoamine transporters in brainstem noradrenergic neurons of long-term repeatedly immobilized rats. Brain Res. 2001;899(1-2):20-35.
    • (2001) Brain Res , vol.899 , Issue.1-2 , pp. 20-35
    • Rusnák, M.1    Kvetnanský, R.2    Jeloková, J.3    Palkovits, M.4
  • 39
    • 84864445857 scopus 로고    scopus 로고
    • Synergistic tonic and phasic activity of the locus coeruleus norepinephrine (LC-NE) arousal system is required for optimal attentional performance
    • Howells FM, Stein DJ, Russell VA. Synergistic tonic and phasic activity of the locus coeruleus norepinephrine (LC-NE) arousal system is required for optimal attentional performance. Metab Brain Dis. 2012;27(3):267-274.
    • (2012) Metab Brain Dis , vol.27 , Issue.3 , pp. 267-274
    • Howells, F.M.1    Stein, D.J.2    Russell, V.A.3
  • 40
    • 0242340372 scopus 로고    scopus 로고
    • Synthesis and in vivo evaluation of novel radiotracers for the in vivo imaging of the norepinephrine transporter
    • Wilson AA, Johnson DP,Mozley D, et al. Synthesis and in vivo evaluation of novel radiotracers for the in vivo imaging of the norepinephrine transporter. Nucl Med Biol. 2003;30(2):85-92.
    • (2003) Nucl Med Biol , vol.30 , Issue.2 , pp. 85-92
    • Wilson, A.A.1    Johnson, D.P.2    Mozley, D.3
  • 41
    • 0036499749 scopus 로고    scopus 로고
    • Altered forebrain neurotransmitter responses to immobilization stress following 3,4-methylenedioxymethamphetamine
    • . Matuszewich L, Filon ME, Finn DA, Yamamoto BK. Altered forebrain neurotransmitter responses to immobilization stress following 3,4-methylenedioxymethamphetamine. Neuroscience. 2002;110(1):41-48.
    • (2002) Neuroscience , vol.110 , Issue.1 , pp. 41-48
    • Matuszewich, L.1    Filon, M.E.2    Finn, D.A.3    Yamamoto, B.K.4
  • 42
    • 84858992258 scopus 로고    scopus 로고
    • Anxiolytic-like actions of reboxetine, venlafaxine and endurance swimming in stressed male rats
    • Lapmanee S, Charoenphandhu N, Krishnamra N, Charoenphandhu J. Anxiolytic-like actions of reboxetine, venlafaxine and endurance swimming in stressed male rats. Behav Brain Res. 2012;231(1):20-28.
    • (2012) Behav Brain Res , vol.231 , Issue.1 , pp. 20-28
    • Lapmanee, S.1    Charoenphandhu, N.2    Krishnamra, N.3    Charoenphandhu, J.4
  • 43
    • 84862116186 scopus 로고    scopus 로고
    • Evidence-based pharmacotherapy of post-traumatic stress disorder (PTSD)
    • Ipser JC, Stein DJ. Evidence-based pharmacotherapy of post-traumatic stress disorder (PTSD). Int J Neuropsychopharmacol. 2012;15(6):825-840.
    • (2012) Int J Neuropsychopharmacol , vol.15 , Issue.6 , pp. 825-840
    • Ipser, J.C.1    Stein, D.J.2
  • 44
    • 84857061992 scopus 로고    scopus 로고
    • Noradrenergic vs serotonergic antidepressant with or without naltrexone for veterans with PTSD and comorbid alcohol dependence
    • Petrakis IL, Ralevski E, Desai N, et al. Noradrenergic vs serotonergic antidepressant with or without naltrexone for veterans with PTSD and comorbid alcohol dependence. Neuropsychopharmacology. 2012;37(4):996-1004.
    • (2012) Neuropsychopharmacology , vol.37 , Issue.4 , pp. 996-1004
    • Petrakis, I.L.1    Ralevski, E.2    Desai, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.