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Volumn 32, Issue 23, 2012, Pages 7832-7842

Engrailed is required in maturing serotonin neurons to regulate the cytoarchitecture and survival of the dorsal raphe nucleus

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; PROTEIN ENGRAILED; PROTEIN ENGRAILED 1; PROTEIN ENGRAILED 2; SEROTONIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 84861870862     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5829-11.2012     Document Type: Article
Times cited : (34)

References (51)
  • 1
    • 4043165474 scopus 로고    scopus 로고
    • Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons
    • Albéri L, Sgadò P, SimonHH (2004) Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons. Development 131:3229-3236.
    • (2004) Development , vol.131 , pp. 3229-3236
    • Albéri, L.1    Sgadò, P.2    Simon, H.H.3
  • 4
    • 33749254952 scopus 로고    scopus 로고
    • En2 knockout mice display neurobehavioral and neurochemical alterations relevant to autism spectrum disorder
    • Cheh MA, Millonig JH, Roselli LM, Ming X, Jacobsen E, Kamdar S, Wagner GC (2006) En2 knockout mice display neurobehavioral and neurochemical alterations relevant to autism spectrum disorder. Brain Res 1116:166-176.
    • (2006) Brain Res , vol.1116 , pp. 166-176
    • Cheh, M.A.1    Millonig, J.H.2    Roselli, L.M.3    Ming, X.4    Jacobsen, E.5    Kamdar, S.6    Wagner, G.C.7
  • 5
    • 74349097700 scopus 로고    scopus 로고
    • The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum
    • Cheng Y, Sudarov A, Szulc KU, Sgaier SK, Stephen D, Turnbull DH, Joyner AL (2010) The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum. Development 137:519-529.
    • (2010) Development , vol.137 , pp. 519-529
    • Cheng, Y.1    Sudarov, A.2    Szulc, K.U.3    Sgaier, S.K.4    Stephen, D.5    Turnbull, D.H.6    Joyner, A.L.7
  • 7
    • 0029960330 scopus 로고    scopus 로고
    • Midbrain development induced by FGF8 in the chick embryo
    • Crossley PH, Martinez S, Martin GR (1996) Midbrain development induced by FGF8 in the chick embryo. Nature 380:66-68.
    • (1996) Nature , vol.380 , pp. 66-68
    • Crossley, P.H.1    Martinez, S.2    Martin, G.R.3
  • 8
    • 0026101890 scopus 로고
    • Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum
    • Davis CA, Holmyard DP, Millen KJ, Joyner AL (1991) Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum. Development 111:287-298.
    • (1991) Development , vol.111 , pp. 287-298
    • Davis, C.A.1    Holmyard, D.P.2    Millen, K.J.3    Joyner, A.L.4
  • 9
    • 82855161336 scopus 로고    scopus 로고
    • Molecular genetics of mouse serotonin neurons across the lifespan
    • Deneris ES (2011) Molecular genetics of mouse serotonin neurons across the lifespan. Neuroscience 197:17-27.
    • (2011) Neuroscience , vol.197 , pp. 17-27
    • Deneris, E.S.1
  • 10
    • 84859215167 scopus 로고    scopus 로고
    • Serotonergic transcriptional networks and potential importance to mental health
    • Deneris ES, Wyler SC (2012) Serotonergic transcriptional networks and potential importance to mental health. Nat Neurosci 15:519-527.
    • (2012) Nat Neurosci , vol.15 , pp. 519-527
    • Deneris, E.S.1    Wyler, S.C.2
  • 12
    • 74949123762 scopus 로고    scopus 로고
    • Serotonergic neurons migrate radially through the neuroepithelium by dynamin-mediated somal translocation
    • Hawthorne AL, Wylie CJ, Landmesser LT, Deneris ES, Silver J (2010) Serotonergic neurons migrate radially through the neuroepithelium by dynamin-mediated somal translocation. J Neurosci 30:420-430.
    • (2010) J Neurosci , vol.30 , pp. 420-430
    • Hawthorne, A.L.1    Wylie, C.J.2    Landmesser, L.T.3    Deneris, E.S.4    Silver, J.5
  • 13
    • 0033492916 scopus 로고    scopus 로고
    • TheETSdomainfactor Pet-1 is an early and precise marker of central 5-HT neurons and interacts with a conserved element in serotonergic genes
    • Hendricks T, Francis N, Fyodorov D, DenerisES (1999) TheETSdomainfactor Pet-1 is an early and precise marker of central 5-HT neurons and interacts with a conserved element in serotonergic genes. J Neurosci 19:10348-10356.
    • (1999) J Neurosci , vol.19 , pp. 10348-10356
    • Hendricks, T.1    Francis, N.2    Fyodorov, D.3    Deneris, E.S.4
  • 16
    • 69649097844 scopus 로고    scopus 로고
    • Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain
    • Jacob J, Storm R, Castro DS, Milton C, Pla P, Guillemot F, Birchmeier C, Briscoe J (2009) Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain. Development 136:2477-2485.
    • (2009) Development , vol.136 , pp. 2477-2485
    • Jacob, J.1    Storm, R.2    Castro, D.S.3    Milton, C.4    Pla, P.5    Guillemot, F.6    Birchmeier, C.7    Briscoe, J.8
  • 18
    • 79951993063 scopus 로고    scopus 로고
    • A genetically defined morphologically and functionally unique subset of 5-HT neurons in the mouse raphe nuclei
    • Kiyasova V, Fernandez SP, Laine J, Stankovski L, Muzerelle A, Doly S, Gaspar P (2011) A genetically defined morphologically and functionally unique subset of 5-HT neurons in the mouse raphe nuclei. J Neurosci 31:2756-2768.
    • (2011) J Neurosci , vol.31 , pp. 2756-2768
    • Kiyasova, V.1    Fernandez, S.P.2    Laine, J.3    Stankovski, L.4    Muzerelle, A.5    Doly, S.6    Gaspar, P.7
  • 19
    • 58149383261 scopus 로고    scopus 로고
    • Serotonergic transcription of human FEV reveals direct GATA factor interactions and fate of Pet-1-deficient serotonin neuron precursors
    • Krueger KC, Deneris ES (2008) Serotonergic transcription of human FEV reveals direct GATA factor interactions and fate of Pet-1-deficient serotonin neuron precursors. J Neurosci 28:12748-12758.
    • (2008) J Neurosci , vol.28 , pp. 12748-12758
    • Krueger, K.C.1    Deneris, E.S.2
  • 20
    • 0030826381 scopus 로고    scopus 로고
    • Pattern deformities and cell loss in Engrailed-2 mutant mice suggest two separate patterning events during cerebellar development
    • Kuemerle B, Zanjani H, Joyner A, Herrup K (1997) Pattern deformities and cell loss in Engrailed-2 mutant mice suggest two separate patterning events during cerebellar development. J Neurosci 17:7881-7889.
    • (1997) J Neurosci , vol.17 , pp. 7881-7889
    • Kuemerle, B.1    Zanjani, H.2    Joyner, A.3    Herrup, K.4
  • 21
    • 0018131910 scopus 로고
    • Developmental organization of raphe serotonin neuron groups in the rat
    • Levitt P, Moore RY (1978) Developmental organization of raphe serotonin neuron groups in the rat. Anat Embryol (Berl) 154:241-251.
    • (1978) Anat Embryol (Berl) , vol.154 , pp. 241-251
    • Levitt, P.1    Moore, R.Y.2
  • 22
    • 0035692010 scopus 로고    scopus 로고
    • Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression
    • Li JY, Joyner AL (2001) Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression. Development 128:4979-4991.
    • (2001) Development , vol.128 , pp. 4979-4991
    • Li, J.Y.1    Joyner, A.L.2
  • 23
    • 0037179758 scopus 로고    scopus 로고
    • Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer
    • Li JY, Lao Z, Joyner AL (2002) Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer. Neuron 36:31-43.
    • (2002) Neuron , vol.36 , pp. 31-43
    • Li, J.Y.1    Lao, Z.2    Joyner, A.L.3
  • 24
    • 0020322892 scopus 로고
    • An immunohistochemical study of serotonin neuron development in the rat: Ascending pathwaysandterminal fields
    • Lidov HG, Molliver ME (1982a) An immunohistochemical study of serotonin neuron development in the rat: ascending pathwaysandterminal fields. Brain Res Bull 8:389-430.
    • (1982) Brain Res Bull , vol.8 , pp. 389-430
    • Lidov, H.G.1    Molliver, M.E.2
  • 25
    • 0020467289 scopus 로고
    • Immunohistochemical study of the development of serotonergic neurons in the rat CNS
    • Lidov HG, Molliver ME (1982b) Immunohistochemical study of the development of serotonergic neurons in the rat CNS. Brain Res Bull 9:559-604.
    • (1982) Brain Res Bull , vol.9 , pp. 559-604
    • Lidov, H.G.1    Molliver, M.E.2
  • 26
    • 0035141207 scopus 로고    scopus 로고
    • ENandGBX2play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region
    • Liu A, JoynerAL (2001) ENandGBX2play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region. Development 128:181-191.
    • (2001) Development , vol.128 , pp. 181-191
    • Liu, A.1    Joyner, A.L.2
  • 27
    • 77957285177 scopus 로고    scopus 로고
    • Pet-1 is required across different stages of life to regulate serotonergic function
    • Liu C, Maejima T, Wyler SC, Casadesus G, Herlitze S, Deneris ES (2010) Pet-1 is required across different stages of life to regulate serotonergic function. Nat Neurosci 13:1190-1198.
    • (2010) Nat Neurosci , vol.13 , pp. 1190-1198
    • Liu, C.1    Maejima, T.2    Wyler, S.C.3    Casadesus, G.4    Herlitze, S.5    Deneris, E.S.6
  • 29
    • 0029913105 scopus 로고    scopus 로고
    • The engrailed and huckebein genes are essential for development of serotonin neurons in the Drosophila CNS
    • Lundell MJ, Chu-LaGraff Q, Doe CQ, Hirsh J (1996) The engrailed and huckebein genes are essential for development of serotonin neurons in the Drosophila CNS. Mol Cell Neurosci 7:46-61.
    • (1996) Mol Cell Neurosci , vol.7 , pp. 46-61
    • Lundell, M.J.1    Chu-la Graff, Q.2    Doe, C.Q.3    Hirsh, J.4
  • 30
    • 0029585838 scopus 로고
    • A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum
    • Millen KJ, Hui CC, Joyner AL (1995) A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum. Development 121:3935-3945.
    • (1995) Development , vol.121 , pp. 3935-3945
    • Millen, K.J.1    Hui, C.C.2    Joyner, A.L.3
  • 33
    • 0036581160 scopus 로고    scopus 로고
    • Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
    • Pfaffl MW, Horgan GW, Dempfle L (2002) Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 30:e36.
    • (2002) Nucleic Acids Res , vol.30
    • Pfaffl, M.W.1    Horgan, G.W.2    Dempfle, L.3
  • 34
    • 14944356461 scopus 로고    scopus 로고
    • A differentially autoregulated Pet-1 enhancer region is a critical target of the transcriptional cascade that governs serotonin neuron development
    • Scott MM, Krueger KC, Deneris ES (2005a) A differentially autoregulated Pet-1 enhancer region is a critical target of the transcriptional cascade that governs serotonin neuron development. J Neurosci 25:2628-2636.
    • (2005) J Neurosci , vol.25 , pp. 2628-2636
    • Scott, M.M.1    Krueger, K.C.2    Deneris, E.S.3
  • 37
    • 34347336583 scopus 로고    scopus 로고
    • Genetic subdivision of the tectum and cerebellum into functionally related regions based on differential sensitivity to engrailed proteins
    • Sgaier SK, Lao Z, Villanueva MP, Berenshteyn F, Stephen D, Turnbull RK, Joyner AL (2007) Genetic subdivision of the tectum and cerebellum into functionally related regions based on differential sensitivity to engrailed proteins. Development 134:2325-2335.
    • (2007) Development , vol.134 , pp. 2325-2335
    • Sgaier, S.K.1    Lao, Z.2    Villanueva, M.P.3    Berenshteyn, F.4    Stephen, D.5    Turnbull, R.K.6    Joyner, A.L.7
  • 38
    • 58149387070 scopus 로고    scopus 로고
    • Engrailed homeobox genes determine the organization of Purkinje cell sagittal stripe gene expression in the adult cerebellum
    • Sillitoe RV, Stephen D, Lao Z, Joyner AL (2008) Engrailed homeobox genes determine the organization of Purkinje cell sagittal stripe gene expression in the adult cerebellum. J Neurosci 28:12150-12162.
    • (2008) J Neurosci , vol.28 , pp. 12150-12162
    • Sillitoe, R.V.1    Stephen, D.2    Lao, Z.3    Joyner, A.L.4
  • 39
    • 77955375508 scopus 로고    scopus 로고
    • Engrailed homeobox genes regulate establishment of the cerebellar afferent circuit map
    • Sillitoe RV, Vogel MW, Joyner AL (2010) Engrailed homeobox genes regulate establishment of the cerebellar afferent circuit map. J Neurosci 30:10015-10024.
    • (2010) J Neurosci , vol.30 , pp. 10015-10024
    • Sillitoe, R.V.1    Vogel, M.W.2    Joyner, A.L.3
  • 41
    • 5444252492 scopus 로고    scopus 로고
    • Midbrain dopaminergic neurons: Control of their cell fate by the engrailed transcription factors
    • Simon HH, Thuret S, Alberi L (2004) Midbrain dopaminergic neurons: control of their cell fate by the engrailed transcription factors. Cell Tissue Res 318:53-61.
    • (2004) Cell Tissue Res , vol.318 , pp. 53-61
    • Simon, H.H.1    Thuret, S.2    Alberi, L.3
  • 42
    • 10644287785 scopus 로고    scopus 로고
    • Engrailed genes control developmental fate of serotonergic and noradrenergic neurons in mid-and hindbrain in a gene dose-dependent manner
    • Simon HH, Scholz C, O'Leary DD (2005) Engrailed genes control developmental fate of serotonergic and noradrenergic neurons in mid-and hindbrain in a gene dose-dependent manner. Mol Cell Neurosci 28:96-105.
    • (2005) Mol Cell Neurosci , vol.28 , pp. 96-105
    • Simon, H.H.1    Scholz, C.2    O'Leary, D.D.3
  • 43
    • 33846804054 scopus 로고    scopus 로고
    • Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1
    • Sonnier L, Le Pen G, Hartmann A, Bizot JC, Trovero F, Krebs MO, Prochiantz A (2007) Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1. J Neurosci 27:1063-1071.
    • (2007) J Neurosci , vol.27 , pp. 1063-1071
    • Sonnier, L.1    le Pen, G.2    Hartmann, A.3    Bizot, J.C.4    Trovero, F.5    Krebs, M.O.6    Prochiantz, A.7
  • 44
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P (1999) Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21:70-71.
    • (1999) Nat Genet , vol.21 , pp. 70-71
    • Soriano, P.1
  • 46
    • 0031053613 scopus 로고    scopus 로고
    • Distribution, quantification, and morphological characteristics of serotonin-immunoreactive cells of the supralemniscal nucleus (B9) and pontomesencephalic reticular formation in the rat
    • Vertes RP, Crane AM (1997) Distribution, quantification, and morphological characteristics of serotonin-immunoreactive cells of the supralemniscal nucleus (B9) and pontomesencephalic reticular formation in the rat. J Comp Neurol 378:411-424.
    • (1997) J Comp Neurol , vol.378 , pp. 411-424
    • Vertes, R.P.1    Crane, A.M.2
  • 47
    • 0020636924 scopus 로고
    • Development of the serotonergic system in the rat embryo: An immunocytochemical study
    • Wallace JA, Lauder JM (1983) Development of the serotonergic system in the rat embryo: an immunocytochemical study. Brain Res Bull 10:459-479.
    • (1983) Brain Res Bull , vol.10 , pp. 459-479
    • Wallace, J.A.1    Lauder, J.M.2
  • 49
    • 0032577445 scopus 로고    scopus 로고
    • FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate
    • Ye W, Shimamura K, Rubenstein JL, Hynes MA, Rosenthal A (1998) FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell 93:755-766.
    • (1998) Cell , vol.93 , pp. 755-766
    • Ye, W.1    Shimamura, K.2    Rubenstein, J.L.3    Hynes, M.A.4    Rosenthal, A.5
  • 50
    • 4043064327 scopus 로고    scopus 로고
    • Cell behaviors and genetic lineages of the mesencephalon and rhombomere 1
    • Zervas M, Millet S, Ahn S, Joyner AL (2004) Cell behaviors and genetic lineages of the mesencephalon and rhombomere 1. Neuron 43:345-357.
    • (2004) Neuron , vol.43 , pp. 345-357
    • Zervas, M.1    Millet, S.2    Ahn, S.3    Joyner, A.L.4
  • 51
    • 33845423914 scopus 로고    scopus 로고
    • Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity
    • Zhao ZQ, Scott M, Chiechio S, Wang JS, Renner KJ, Gereau RW 4th, Johnson RL, Deneris ES, Chen ZF (2006) Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity. J Neurosci 26:12781-12788.
    • (2006) J Neurosci , vol.26 , pp. 12781-12788
    • Zhao, Z.Q.1    Scott, M.2    Chiechio, S.3    Wang, J.S.4    Renner, K.J.5    Gereau IV, R.W.6    Johnson, R.L.7    Deneris, E.S.8    Chen, Z.F.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.