Metallothionein plays a prominent role in the prevention of diabetic nephropathy by sulforaphane via up-regulation of Nrf2

Free Radical Biology and Medicine

Volumn 89, Issue , 2015, Pages 431-442

  Wu, Hao ^a,b   Kong, Lili ^a,b   Cheng, Yanli ^b,c   Zhang, Zhiguo ^b,c   Wang, Yangwei ^a   Luo, Manyu ^a,b   Tan, Yi ^b,d   Chen, Xiangmei ^e   Miao, Lining ^a   Cai, Lu ^b,d  

^a THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

^b University of Louisville School of Medicine   (United States)

^c THE FIRST HOSPITAL OF JILIN UNIVERSITY   (China)

^d WENZHOU MEDICAL UNIVERSITY   (China)

^e CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Diabetes; Fibrosis; Inflammation; Kidney; Oxidative stress

Indexed keywords

MESSENGER RNA; METALLOTHIONEIN; SULFORAPHANE; TRANSCRIPTION FACTOR NRF2; ANTINEOPLASTIC AGENT; ISOTHIOCYANIC ACID DERIVATIVE; SULFORAFAN;

ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; INFLAMMATION; KIDNEY FIBROSIS; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENAL PROTECTION; UPREGULATION; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; COMPLICATION; DIABETIC NEPHROPATHIES; ENZYME IMMUNOASSAY; EXPERIMENTAL DIABETES MELLITUS; GENETICS; KNOCKOUT MOUSE; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; PATHOPHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ANTICARCINOGENIC AGENTS; BLOTTING, WESTERN; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; IMMUNOENZYME TECHNIQUES; ISOTHIOCYANATES; MALE; METALLOTHIONEIN; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84943656399     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.08.009     Document Type: Article

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