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Volumn 63, Issue 9, 2014, Pages 2904-2905

Is there a sweet spot for nrf2 activation in the treatment of diabetic kidney disease?

Author keywords

[No Author keywords available]

Indexed keywords

BARDOXOLONE METHYL; KELCH LIKE ECH ASSOCIATED PROTEIN 1; TRANSCRIPTION FACTOR NRF2; UBIQUITIN PROTEIN LIGASE;

EID: 84906712847     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0829     Document Type: Note
Times cited : (13)

References (12)
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  • 3
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    • National Kidney Foundation
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  • 4
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    • Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
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    • Kensler, T.W.1    Wakabayashi, N.2    Biswal, S.3
  • 5
    • 84906699232 scopus 로고    scopus 로고
    • Derivative of bardoxolone methyl, dh404, in an inverse dose-dependent manner lessens diabetes-Associated atherosclerosis and improves diabetic kidney disease
    • Tan SM, Sharma A, Stefanovic N, et al. Derivative of bardoxolone methyl, dh404, in an inverse dose-dependent manner lessens diabetes-Associated atherosclerosis and improves diabetic kidney disease. Diabetes 2014;63:3091-3103
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  • 6
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    • Dinkova-Kostova AT, Liby KT, Stephenson KK, et al. Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress. Proc Natl Acad Sci U S A 2005;102:4584-4589
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 4584-4589
    • Dinkova-Kostova, A.T.1    Liby, K.T.2    Stephenson, K.K.3
  • 7
    • 79960855656 scopus 로고    scopus 로고
    • BEAM Study Investigators. Bardoxolone methyl and kidney function in CKD with type 2 diabetes
    • Pergola PE, Raskin P, Toto RD, et al.; BEAM Study Investigators. Bardoxolone methyl and kidney function in CKD with type 2 diabetes. N Engl J Med 2011;365:327-336
    • (2011) N Engl J Med , vol.365 , pp. 327-336
    • Pergola, P.E.1    Raskin, P.2    Toto, R.D.3
  • 8
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    • New therapies for diabetic kidney disease
    • Himmelfarb J, Tuttle KR. New therapies for diabetic kidney disease. N Engl J Med 2013;369:2549-2550
    • (2013) N Engl J Med , vol.369 , pp. 2549-2550
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  • 11
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    • Analogs of bardoxolone methyl worsen diabetic nephropathy in rats with additional adverse effects
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.