The Deacetylase Sirtuin 1 Regulates Human Papillomavirus Replication by Modulating Histone Acetylation and Recruitment of DNA Damage Factors NBS1 and Rad51 to Viral Genomes

PLoS Pathogens

Volumn 11, Issue 9, 2015, Pages

  Langsfeld, Erika S ^a   Bodily, Jason M ^b   Laimins, Laimonis A ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; HISTONE; NIBRIN; PROTEIN E6; PROTEIN E7; RAD51 PROTEIN; SIRTUIN 1; CELL CYCLE PROTEIN; NBN PROTEIN, HUMAN; NUCLEAR PROTEIN; RAD51 PROTEIN, HUMAN; SIRT1 PROTEIN, HUMAN; SMALL INTERFERING RNA;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA DAMAGE; GENE AMPLIFICATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 31; IMMUNOFLUORESCENCE TEST; NORTHERN BLOTTING; SOUTHERN BLOTTING; VIRUS REPLICATION; WART VIRUS; WESTERN BLOTTING; ACETYLATION; CELL CULTURE; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC TRANSDUCTION; IMMUNOBLOTTING; LIFE CYCLE STAGE; METABOLISM; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTION; PHYSIOLOGY;

ACETYLATION; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; FLUORESCENT ANTIBODY TECHNIQUE; HISTONES; HUMANS; IMMUNOBLOTTING; LIFE CYCLE STAGES; NUCLEAR PROTEINS; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; RAD51 RECOMBINASE; RNA, SMALL INTERFERING; SIRTUIN 1; TRANSDUCTION, GENETIC; VIRUS REPLICATION;

EID: 84943558756     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005181     Document Type: Article

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