메뉴 건너뛰기




Volumn 9, Issue 10, 2013, Pages

Inactivation of p53 Rescues the Maintenance of High Risk HPV DNA Genomes Deficient in Expression of E6

Author keywords

[No Author keywords available]

Indexed keywords

DACTINOMYCIN; PROTEIN E6; PROTEIN P53; VIRUS DNA;

EID: 84887302583     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003717     Document Type: Article
Times cited : (25)

References (89)
  • 1
  • 2
    • 0036784584 scopus 로고    scopus 로고
    • Life cycle heterogeneity in animal models of human papillomavirus-associated disease
    • Peh WL, Middleton K, Christensen N, Nicholls P, Egawa K, et al. (2002) Life cycle heterogeneity in animal models of human papillomavirus-associated disease. Journal of virology 76: 10401-10416.
    • (2002) Journal of Virology , vol.76 , pp. 10401-10416
    • Peh, W.L.1    Middleton, K.2    Christensen, N.3    Nicholls, P.4    Egawa, K.5
  • 3
    • 84875771195 scopus 로고    scopus 로고
    • The biology and life-cycle of human papillomaviruses
    • Doorbar J, Quint W, Banks L, Bravo IG, Stoler M, et al. (2012) The biology and life-cycle of human papillomaviruses. Vaccine 30 Suppl 5: F55-70.
    • (2012) Vaccine , vol.30 , Issue.SUPPL.
    • Doorbar, J.1    Quint, W.2    Banks, L.3    Bravo, I.G.4    Stoler, M.5
  • 4
    • 0030820343 scopus 로고    scopus 로고
    • Synthesis of infectious human papillomavirus type 18 in differentiating epithelium transfected with viral DNA
    • Meyers C, Mayer TJ, Ozbun MA, (1997) Synthesis of infectious human papillomavirus type 18 in differentiating epithelium transfected with viral DNA. Journal of virology 71: 7381-7386.
    • (1997) Journal of Virology , vol.71 , pp. 7381-7386
    • Meyers, C.1    Mayer, T.J.2    Ozbun, M.A.3
  • 5
    • 0033619108 scopus 로고    scopus 로고
    • Establishment of the human papillomavirus type 16 (HPV-16) life cycle in an immortalized human foreskin keratinocyte cell line
    • Flores ER, Allen-Hoffmann BL, Lee D, Sattler CA, Lambert PF, (1999) Establishment of the human papillomavirus type 16 (HPV-16) life cycle in an immortalized human foreskin keratinocyte cell line. Virology 262: 344.
    • (1999) Virology , vol.262 , pp. 344
    • Flores, E.R.1    Allen-Hoffmann, B.L.2    Lee, D.3    Sattler, C.A.4    Lambert, P.F.5
  • 9
    • 0029041842 scopus 로고
    • Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. International biological study on cervical cancer (IBSCC) Study Group
    • Bosch FX, Manos MM, Munoz N, Sherman M, Jansen AM, et al. (1995) Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. International biological study on cervical cancer (IBSCC) Study Group. Journal of the National Cancer Institute 87: 796-802.
    • (1995) Journal of the National Cancer Institute , vol.87 , pp. 796-802
    • Bosch, F.X.1    Manos, M.M.2    Munoz, N.3    Sherman, M.4    Jansen, A.M.5
  • 11
    • 21144433509 scopus 로고    scopus 로고
    • The carcinogenicity of human papillomavirus types reflects viral evolution
    • Schiffman M, Herrero R, Desalle R, Hildesheim A, Wacholder S, et al. (2005) The carcinogenicity of human papillomavirus types reflects viral evolution. Virology 337: 76-84.
    • (2005) Virology , vol.337 , pp. 76-84
    • Schiffman, M.1    Herrero, R.2    Desalle, R.3    Hildesheim, A.4    Wacholder, S.5
  • 13
    • 57149092794 scopus 로고    scopus 로고
    • Replication and partitioning of papillomavirus genomes
    • McBride AA, (2008) Replication and partitioning of papillomavirus genomes. Advances in virus research 72: 155-205.
    • (2008) Advances in Virus Research , vol.72 , pp. 155-205
    • McBride, A.A.1
  • 17
    • 0026034125 scopus 로고
    • Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames
    • Ustav M, Stenlund A, (1991) Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames. EMBO J 10: 449-457.
    • (1991) EMBO J , vol.10 , pp. 449-457
    • Ustav, M.1    Stenlund, A.2
  • 18
    • 0025820471 scopus 로고
    • Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation
    • Bedell MA, Hudson JB, Golub TR, Turyk ME, Hosken M, et al. (1991) Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation. Journal of virology 65: 2254-2260.
    • (1991) Journal of Virology , vol.65 , pp. 2254-2260
    • Bedell, M.A.1    Hudson, J.B.2    Golub, T.R.3    Turyk, M.E.4    Hosken, M.5
  • 20
    • 0030745931 scopus 로고    scopus 로고
    • Induction of human papillomavirus type 18 late gene expression and genomic amplification in organotypic cultures from transfected DNA templates
    • Frattini MG, Lim HB, Doorbar J, Laimins LA, (1997) Induction of human papillomavirus type 18 late gene expression and genomic amplification in organotypic cultures from transfected DNA templates. Journal of virology 71: 7068-7072.
    • (1997) Journal of Virology , vol.71 , pp. 7068-7072
    • Frattini, M.G.1    Lim, H.B.2    Doorbar, J.3    Laimins, L.A.4
  • 21
    • 1242319382 scopus 로고    scopus 로고
    • Roles of the E6 and E7 proteins in the life cycle of low-risk human papillomavirus type 11
    • Oh ST, Longworth MS, Laimins LA, (2004) Roles of the E6 and E7 proteins in the life cycle of low-risk human papillomavirus type 11. Journal of virology 78: 2620.
    • (2004) Journal of Virology , vol.78 , pp. 2620
    • Oh, S.T.1    Longworth, M.S.2    Laimins, L.A.3
  • 22
    • 0033947269 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E7 oncogene is required for the productive stage of the viral life cycle
    • Flores ER, Allen-Hoffmann BL, Lee D, Lambert PF, (2000) The human papillomavirus type 16 E7 oncogene is required for the productive stage of the viral life cycle. Journal of virology 74: 6622.
    • (2000) Journal of Virology , vol.74 , pp. 6622
    • Flores, E.R.1    Allen-Hoffmann, B.L.2    Lee, D.3    Lambert, P.F.4
  • 24
    • 20644458111 scopus 로고    scopus 로고
    • The role of the human papillomavirus type 18 E7 oncoprotein during the complete viral life cycle
    • McLaughlin-Drubin ME, Bromberg-White JL, Meyers C, (2005) The role of the human papillomavirus type 18 E7 oncoprotein during the complete viral life cycle. Virology 338: 61.
    • (2005) Virology , vol.338 , pp. 61
    • McLaughlin-Drubin, M.E.1    Bromberg-White, J.L.2    Meyers, C.3
  • 25
    • 33746538383 scopus 로고    scopus 로고
    • The human papillomavirus type 11 E1∧E4 protein is not essential for viral genome amplification
    • Fang L, Budgeon LR, Doorbar J, Briggs ER, Howett MK, (2006) The human papillomavirus type 11 E1∧E4 protein is not essential for viral genome amplification. Virology 351: 271-279.
    • (2006) Virology , vol.351 , pp. 271-279
    • Fang, L.1    Budgeon, L.R.2    Doorbar, J.3    Briggs, E.R.4    Howett, M.K.5
  • 26
    • 26444441402 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E1circumflexE4 contributes to multiple facets of the papillomavirus life cycle
    • Nakahara T, Peh WL, Doorbar J, Lee D, Lambert PF, (2005) Human papillomavirus type 16 E1circumflexE4 contributes to multiple facets of the papillomavirus life cycle. Journal of virology 79: 13150.
    • (2005) Journal of Virology , vol.79 , pp. 13150
    • Nakahara, T.1    Peh, W.L.2    Doorbar, J.3    Lee, D.4    Lambert, P.F.5
  • 27
    • 18744369062 scopus 로고    scopus 로고
    • Role of the E1-E4 protein in the differentiation-dependent life cycle of human papillomavirus type 31
    • Wilson R, Fehrmann F, Laimins LA, (2005) Role of the E1-E4 protein in the differentiation-dependent life cycle of human papillomavirus type 31. Journal of virology 79: 6732-6740.
    • (2005) Journal of Virology , vol.79 , pp. 6732-6740
    • Wilson, R.1    Fehrmann, F.2    Laimins, L.A.3
  • 28
    • 34247626297 scopus 로고    scopus 로고
    • The full-length E1E4 protein of human papillomavirus type 18 modulates differentiation-dependent viral DNA amplification and late gene expression
    • Wilson R, Ryan GB, Knight GL, Laimins LA, Roberts S, (2007) The full-length E1E4 protein of human papillomavirus type 18 modulates differentiation-dependent viral DNA amplification and late gene expression. Virology 362: 453-460.
    • (2007) Virology , vol.362 , pp. 453-460
    • Wilson, R.1    Ryan, G.B.2    Knight, G.L.3    Laimins, L.A.4    Roberts, S.5
  • 29
    • 84857934131 scopus 로고    scopus 로고
    • The E1 protein of human papillomavirus type 16 is dispensable for maintenance replication of the viral genome
    • Egawa N, Nakahara T, Ohno S, Narisawa-Saito M, Yugawa T, et al. (2012) The E1 protein of human papillomavirus type 16 is dispensable for maintenance replication of the viral genome. Journal of virology 86: 3276-3283.
    • (2012) Journal of Virology , vol.86 , pp. 3276-3283
    • Egawa, N.1    Nakahara, T.2    Ohno, S.3    Narisawa-Saito, M.4    Yugawa, T.5
  • 30
    • 0036349058 scopus 로고    scopus 로고
    • E1 protein of bovine papillomavirus 1 is not required for the maintenance of viral plasmid DNA replication
    • Kim K, Lambert PF, (2002) E1 protein of bovine papillomavirus 1 is not required for the maintenance of viral plasmid DNA replication. Virology 293: 10-14.
    • (2002) Virology , vol.293 , pp. 10-14
    • Kim, K.1    Lambert, P.F.2
  • 31
    • 58849121969 scopus 로고    scopus 로고
    • Robust production and passaging of infectious HPV in squamous epithelium of primary human keratinocytes
    • Wang H-K, Duffy AA, Broker TR, Chow LT, (2009) Robust production and passaging of infectious HPV in squamous epithelium of primary human keratinocytes. Genes & development 23: 181-194.
    • (2009) Genes & Development , vol.23 , pp. 181-194
    • Wang, H.-K.1    Duffy, A.A.2    Broker, T.R.3    Chow, L.T.4
  • 33
    • 0037369075 scopus 로고    scopus 로고
    • Quantitative role of the human papillomavirus type 16 E5 gene during the productive stage of the viral life cycle
    • Genther SM, Sterling S, Duensing S, Munger K, Sattler C, et al. (2003) Quantitative role of the human papillomavirus type 16 E5 gene during the productive stage of the viral life cycle. Journal of virology 77: 2832.
    • (2003) Journal of Virology , vol.77 , pp. 2832
    • Genther, S.M.1    Sterling, S.2    Duensing, S.3    Munger, K.4    Sattler, C.5
  • 34
    • 0023082241 scopus 로고
    • Identification of early proteins of the human papilloma viruses type 16 (HPV 16) and type 18 (HPV 18) in cervical carcinoma cells
    • Seedorf K, Oltersdorf T, Krammer G, Rowekamp W, (1987) Identification of early proteins of the human papilloma viruses type 16 (HPV 16) and type 18 (HPV 18) in cervical carcinoma cells. The EMBO journal 6: 139-144.
    • (1987) The EMBO Journal , vol.6 , pp. 139-144
    • Seedorf, K.1    Oltersdorf, T.2    Krammer, G.3    Rowekamp, W.4
  • 35
    • 0042552760 scopus 로고
    • Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer-derived cell line and identification of the E7 protein
    • Smotkin D, Wettstein FO, (1986) Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer-derived cell line and identification of the E7 protein. Proceedings of the National Academy of Sciences of the United States of America 83: 4680.
    • (1986) Proceedings of the National Academy of Sciences of the United States of America , vol.83 , pp. 4680
    • Smotkin, D.1    Wettstein, F.O.2
  • 36
    • 0024573764 scopus 로고
    • Oncogenic and nononcogenic human genital papillomaviruses generate the E7 mRNA by different mechanisms
    • Smotkin D, Prokoph H, Wettstein FO, (1989) Oncogenic and nononcogenic human genital papillomaviruses generate the E7 mRNA by different mechanisms. The Journal of Virology 63: 1441.
    • (1989) The Journal of Virology , vol.63 , pp. 1441
    • Smotkin, D.1    Prokoph, H.2    Wettstein, F.O.3
  • 37
    • 0026344660 scopus 로고
    • Human papillomavirus type 16 E6 proteins with glycine substitution for cysteine in the metal-binding motif
    • Kanda T, Watanabe S, Zanma S, Sato H, Furuno A, et al. (1991) Human papillomavirus type 16 E6 proteins with glycine substitution for cysteine in the metal-binding motif. Virology 185: 536-543.
    • (1991) Virology , vol.185 , pp. 536-543
    • Kanda, T.1    Watanabe, S.2    Zanma, S.3    Sato, H.4    Furuno, A.5
  • 39
    • 0033776810 scopus 로고    scopus 로고
    • Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase
    • Nakagawa S, Huibregtse JM, (2000) Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase. Molecular and cellular biology 20: 8244.
    • (2000) Molecular and Cellular Biology , vol.20 , pp. 8244
    • Nakagawa, S.1    Huibregtse, J.M.2
  • 40
    • 0023116091 scopus 로고
    • Nucleotide sequence and comparative analysis of the human papillomavirus type 18 genome. Phylogeny of papillomaviruses and repeated structure of the E6 and E7 gene products
    • Cole ST, Danos O, (1987) Nucleotide sequence and comparative analysis of the human papillomavirus type 18 genome. Phylogeny of papillomaviruses and repeated structure of the E6 and E7 gene products. Journal of molecular biology 193: 599-608.
    • (1987) Journal of Molecular Biology , vol.193 , pp. 599-608
    • Cole, S.T.1    Danos, O.2
  • 41
    • 0024512974 scopus 로고
    • Papillomavirus polypeptides E6 and E7 are zinc-binding proteins
    • Barbosa MS, Lowy DR, Schiller JT, (1989) Papillomavirus polypeptides E6 and E7 are zinc-binding proteins. Journal of virology 63: 1404-1407.
    • (1989) Journal of Virology , vol.63 , pp. 1404-1407
    • Barbosa, M.S.1    Lowy, D.R.2    Schiller, J.T.3
  • 43
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner M, Werness BA, Huibregtse JM, Levine AJ, Howley PM, (1990) The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63: 1129.
    • (1990) Cell , vol.63 , pp. 1129
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 44
    • 0027358723 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • Scheffner M, Huibregtse JM, Vierstra RD, Howley PM, (1993) The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75: 495-505.
    • (1993) Cell , vol.75 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 45
    • 0025932933 scopus 로고
    • A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18
    • Huibregtse JM, Scheffner M, Howley PM, (1991) A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. The EMBO journal 10: 4129-4135.
    • (1991) The EMBO Journal , vol.10 , pp. 4129-4135
    • Huibregtse, J.M.1    Scheffner, M.2    Howley, P.M.3
  • 46
    • 0025988293 scopus 로고
    • Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation
    • Crook T, Tidy JA, Vousden KH, (1991) Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation. Cell 67: 547.
    • (1991) Cell , vol.67 , pp. 547
    • Crook, T.1    Tidy, J.A.2    Vousden, K.H.3
  • 47
    • 0036827961 scopus 로고    scopus 로고
    • Genetic analysis of high-risk e6 in episomal maintenance of human papillomavirus genomes in primary human keratinocytes
    • Park RB, Androphy EJ, (2002) Genetic analysis of high-risk e6 in episomal maintenance of human papillomavirus genomes in primary human keratinocytes. Journal of virology 76: 11359.
    • (2002) Journal of Virology , vol.76 , pp. 11359
    • Park, R.B.1    Androphy, E.J.2
  • 48
    • 0032816001 scopus 로고    scopus 로고
    • Multiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cells
    • Liu Y, Chen JJ, Gao Q, Dalal S, Hong Y, et al. (1999) Multiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cells. Journal of virology 73: 7297.
    • (1999) Journal of Virology , vol.73 , pp. 7297
    • Liu, Y.1    Chen, J.J.2    Gao, Q.3    Dalal, S.4    Hong, Y.5
  • 49
    • 33846015774 scopus 로고    scopus 로고
    • Analysis of the roles of E6 binding to E6TP1 and nuclear localization in the human papillomavirus type 31 life cycle
    • Lee C, Wooldridge TR, Laimins LA, (2007) Analysis of the roles of E6 binding to E6TP1 and nuclear localization in the human papillomavirus type 31 life cycle. Virology 358: 201.
    • (2007) Virology , vol.358 , pp. 201
    • Lee, C.1    Wooldridge, T.R.2    Laimins, L.A.3
  • 51
    • 33644837882 scopus 로고    scopus 로고
    • Using an immortalized cell line to study the HPV life cycle in organotypic "raft" cultures
    • Lambert PF, Ozbun MA, Collins A, Holmgren S, Lee D, et al. (2005) Using an immortalized cell line to study the HPV life cycle in organotypic "raft" cultures. Methods in molecular medicine 119: 141-155.
    • (2005) Methods in Molecular Medicine , vol.119 , pp. 141-155
    • Lambert, P.F.1    Ozbun, M.A.2    Collins, A.3    Holmgren, S.4    Lee, D.5
  • 52
    • 0027079358 scopus 로고
    • The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein
    • Mietz JA, Unger T, Huibregtse JM, Howley PM, (1992) The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. The EMBO journal 11: 5013.
    • (1992) The EMBO Journal , vol.11 , pp. 5013
    • Mietz, J.A.1    Unger, T.2    Huibregtse, J.M.3    Howley, P.M.4
  • 53
    • 0032487675 scopus 로고    scopus 로고
    • Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells
    • Kiyono T, Foster SA, Koop JI, McDougall JK, Galloway DA, et al. (1998) Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature 396: 84.
    • (1998) Nature , vol.396 , pp. 84
    • Kiyono, T.1    Foster, S.A.2    Koop, J.I.3    McDougall, J.K.4    Galloway, D.A.5
  • 54
    • 0030008177 scopus 로고    scopus 로고
    • Telomerase activation by the E6 gene product of human papillomavirus type 16
    • Klingelhutz AJ, Foster SA, McDougall JK, (1996) Telomerase activation by the E6 gene product of human papillomavirus type 16. Nature 380: 79.
    • (1996) Nature , vol.380 , pp. 79
    • Klingelhutz, A.J.1    Foster, S.A.2    McDougall, J.K.3
  • 55
    • 0027941170 scopus 로고
    • The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest
    • Foster SA, Demers GW, Etscheid BG, Galloway DA, (1994) The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest. Journal of virology 68: 5698.
    • (1994) Journal of Virology , vol.68 , pp. 5698
    • Foster, S.A.1    Demers, G.W.2    Etscheid, B.G.3    Galloway, D.A.4
  • 56
    • 36348949210 scopus 로고    scopus 로고
    • Human papillomavirus E6 proteins mediate resistance to interferon-induced growth arrest through inhibition of p53 acetylation
    • Hebner C, Beglin M, Laimins LA, (2007) Human papillomavirus E6 proteins mediate resistance to interferon-induced growth arrest through inhibition of p53 acetylation. Journal of virology 81: 12740.
    • (2007) Journal of Virology , vol.81 , pp. 12740
    • Hebner, C.1    Beglin, M.2    Laimins, L.A.3
  • 57
    • 33751573462 scopus 로고    scopus 로고
    • MDMX regulation of p53 response to ribosomal stress
    • Gilkes DM, Chen L, Chen J, (2006) MDMX regulation of p53 response to ribosomal stress. The EMBO journal 25: 5614-5625.
    • (2006) The EMBO Journal , vol.25 , pp. 5614-5625
    • Gilkes, D.M.1    Chen, L.2    Chen, J.3
  • 60
    • 0026446686 scopus 로고
    • Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding
    • Shaulian E, Zauberman A, Ginsberg D, Oren M, (1992) Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding. Molecular and cellular biology 12: 5581.
    • (1992) Molecular and Cellular Biology , vol.12 , pp. 5581
    • Shaulian, E.1    Zauberman, A.2    Ginsberg, D.3    Oren, M.4
  • 61
    • 0028294898 scopus 로고
    • Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal
    • Gottlieb E, Haffner R, von Ruden T, Wagner EF, Oren M, (1994) Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal. The EMBO journal 13: 1368-1374.
    • (1994) The EMBO Journal , vol.13 , pp. 1368-1374
    • Gottlieb, E.1    Haffner, R.2    von Ruden, T.3    Wagner, E.F.4    Oren, M.5
  • 62
    • 0343044332 scopus 로고    scopus 로고
    • Effects on normal fibroblasts and neuroblastoma cells of the activation of the p53 response by the nuclear export inhibitor leptomycin B
    • Smart P, Lane EB, Lane DP, Midgley C, Vojtesek B, et al. (1999) Effects on normal fibroblasts and neuroblastoma cells of the activation of the p53 response by the nuclear export inhibitor leptomycin B. Oncogene 18: 7378-7386.
    • (1999) Oncogene , vol.18 , pp. 7378-7386
    • Smart, P.1    Lane, E.B.2    Lane, D.P.3    Midgley, C.4    Vojtesek, B.5
  • 63
    • 0028930859 scopus 로고
    • Transcriptional repression by the C-terminal domain of p53
    • Shaulian E, Haviv I, Shaul Y, Oren M, (1995) Transcriptional repression by the C-terminal domain of p53. Oncogene 10: 671-680.
    • (1995) Oncogene , vol.10 , pp. 671-680
    • Shaulian, E.1    Haviv, I.2    Shaul, Y.3    Oren, M.4
  • 64
    • 0032530486 scopus 로고    scopus 로고
    • DNA damage activates p53 through a phosphorylation-acetylation cascade
    • Sakaguchi K, Herrera JE, Saito S, Miki T, Bustin M, et al. (1998) DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes & development 12: 2831-2841.
    • (1998) Genes & Development , vol.12 , pp. 2831-2841
    • Sakaguchi, K.1    Herrera, J.E.2    Saito, S.3    Miki, T.4    Bustin, M.5
  • 65
    • 79955907419 scopus 로고    scopus 로고
    • Stabilization of HPV16 E6 protein by PDZ proteins, and potential implications for genome maintenance
    • Nicolaides L, Davy C, Raj K, Kranjec C, Banks L, et al. (2011) Stabilization of HPV16 E6 protein by PDZ proteins, and potential implications for genome maintenance. Virology 414: 137-145.
    • (2011) Virology , vol.414 , pp. 137-145
    • Nicolaides, L.1    Davy, C.2    Raj, K.3    Kranjec, C.4    Banks, L.5
  • 66
    • 0031903184 scopus 로고    scopus 로고
    • p53 protein is a suppressor of papillomavirus DNA amplificational replication
    • Lepik D, Ilves I, Kristjuhan A, Maimets T, Ustav M, (1998) p53 protein is a suppressor of papillomavirus DNA amplificational replication. Journal of virology 72: 6822-6831.
    • (1998) Journal of Virology , vol.72 , pp. 6822-6831
    • Lepik, D.1    Ilves, I.2    Kristjuhan, A.3    Maimets, T.4    Ustav, M.5
  • 67
    • 0033576648 scopus 로고    scopus 로고
    • Interaction between the HPV-16 E2 transcriptional activator and p53
    • Massimi P, Pim D, Bertoli C, Bouvard V, Banks L, (1999) Interaction between the HPV-16 E2 transcriptional activator and p53. Oncogene 18: 7748-7754.
    • (1999) Oncogene , vol.18 , pp. 7748-7754
    • Massimi, P.1    Pim, D.2    Bertoli, C.3    Bouvard, V.4    Banks, L.5
  • 69
    • 0032923884 scopus 로고    scopus 로고
    • Long-term episomal maintenance of bovine papillomavirus type 1 plasmids is determined by attachment to host chromosomes, which Is mediated by the viral E2 protein and its binding sites
    • Ilves I, Kivi S, Ustav M, (1999) Long-term episomal maintenance of bovine papillomavirus type 1 plasmids is determined by attachment to host chromosomes, which Is mediated by the viral E2 protein and its binding sites. Journal of virology 73: 4404.
    • (1999) Journal of Virology , vol.73 , pp. 4404
    • Ilves, I.1    Kivi, S.2    Ustav, M.3
  • 70
    • 0026564760 scopus 로고
    • Transcriptional activation of several heterologous promoters by the E6 protein of human papillomavirus type 16
    • Desaintes C, Hallez S, Van Alphen P, Burny A, (1992) Transcriptional activation of several heterologous promoters by the E6 protein of human papillomavirus type 16. Journal of virology 66: 325-333.
    • (1992) Journal of Virology , vol.66 , pp. 325-333
    • Desaintes, C.1    Hallez, S.2    Van Alphen, P.3    Burny, A.4
  • 71
    • 0028071697 scopus 로고
    • Transcription-modulatory activity of full-length E6 and E6*I proteins of human papillomavirus type 16
    • Shirasawa H, Jin MH, Shimizu K, Akutsu N, Shino Y, et al. (1994) Transcription-modulatory activity of full-length E6 and E6*I proteins of human papillomavirus type 16. Virology 203: 36-42.
    • (1994) Virology , vol.203 , pp. 36-42
    • Shirasawa, H.1    Jin, M.H.2    Shimizu, K.3    Akutsu, N.4    Shino, Y.5
  • 72
    • 84871981670 scopus 로고    scopus 로고
    • Engagement of the ATR-dependent DNA damage response at the human papillomavirus 18 replication centers during the initial amplification
    • Reinson T, Toots M, Kadaja M, Pipitch R, Allik M, et al. (2013) Engagement of the ATR-dependent DNA damage response at the human papillomavirus 18 replication centers during the initial amplification. Journal of virology 87: 951-964.
    • (2013) Journal of Virology , vol.87 , pp. 951-964
    • Reinson, T.1    Toots, M.2    Kadaja, M.3    Pipitch, R.4    Allik, M.5
  • 74
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • Rogakou EP, Boon C, Redon C, Bonner WM, (1999) Megabase chromatin domains involved in DNA double-strand breaks in vivo. The Journal of cell biology 146: 905-916.
    • (1999) The Journal of Cell Biology , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 75
    • 0036789173 scopus 로고    scopus 로고
    • Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody
    • Sedelnikova OA, Rogakou EP, Panyutin IG, Bonner WM, (2002) Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody. Radiation research 158: 486-492.
    • (2002) Radiation Research , vol.158 , pp. 486-492
    • Sedelnikova, O.A.1    Rogakou, E.P.2    Panyutin, I.G.3    Bonner, W.M.4
  • 76
    • 84866178768 scopus 로고    scopus 로고
    • Human papillomaviruses recruit cellular DNA repair and homologous recombination factors to viral replication centers
    • Gillespie KA, Mehta KP, Laimins LA, Moody CA, (2012) Human papillomaviruses recruit cellular DNA repair and homologous recombination factors to viral replication centers. Journal of virology 86: 9520-9526.
    • (2012) Journal of Virology , vol.86 , pp. 9520-9526
    • Gillespie, K.A.1    Mehta, K.P.2    Laimins, L.A.3    Moody, C.A.4
  • 77
    • 80052298198 scopus 로고    scopus 로고
    • The papillomavirus E1 helicase activates a cellular DNA damage response in viral replication foci
    • Sakakibara N, Mitra R, McBride AA, (2011) The papillomavirus E1 helicase activates a cellular DNA damage response in viral replication foci. Journal of virology 85: 8981-8995.
    • (2011) Journal of Virology , vol.85 , pp. 8981-8995
    • Sakakibara, N.1    Mitra, R.2    McBride, A.A.3
  • 78
    • 0033552595 scopus 로고    scopus 로고
    • Regulation of p53 in response to DNA damage
    • Lakin ND, Jackson SP, (1999) Regulation of p53 in response to DNA damage. Oncogene 18: 7644-7655.
    • (1999) Oncogene , vol.18 , pp. 7644-7655
    • Lakin, N.D.1    Jackson, S.P.2
  • 79
    • 0041662272 scopus 로고    scopus 로고
    • Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence
    • Takaoka A, Hayakawa S, Yanai H, Stoiber D, Negishi H, et al. (2003) Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence. Nature 424: 516-523.
    • (2003) Nature , vol.424 , pp. 516-523
    • Takaoka, A.1    Hayakawa, S.2    Yanai, H.3    Stoiber, D.4    Negishi, H.5
  • 83
    • 0036334198 scopus 로고    scopus 로고
    • Long-term effect of interferon on keratinocytes that maintain human papillomavirus type 31
    • Chang YE, Pena L, Sen GC, Park JK, Laimins LA, (2002) Long-term effect of interferon on keratinocytes that maintain human papillomavirus type 31. Journal of virology 76: 8864-8874.
    • (2002) Journal of Virology , vol.76 , pp. 8864-8874
    • Chang, Y.E.1    Pena, L.2    Sen, G.C.3    Park, J.K.4    Laimins, L.A.5
  • 84
    • 33750440566 scopus 로고    scopus 로고
    • Interferon-beta treatment of cervical keratinocytes naturally infected with human papillomavirus 16 episomes promotes rapid reduction in episome numbers and emergence of latent integrants
    • Herdman MT, Pett MR, Roberts I, Alazawi WO, Teschendorff AE, et al. (2006) Interferon-beta treatment of cervical keratinocytes naturally infected with human papillomavirus 16 episomes promotes rapid reduction in episome numbers and emergence of latent integrants. Carcinogenesis 27: 2341-2353.
    • (2006) Carcinogenesis , vol.27 , pp. 2341-2353
    • Herdman, M.T.1    Pett, M.R.2    Roberts, I.3    Alazawi, W.O.4    Teschendorff, A.E.5
  • 85
    • 0033998608 scopus 로고    scopus 로고
    • Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31
    • Chang YE, Laimins LA, (2000) Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31. Journal of virology 74: 4174-4182.
    • (2000) Journal of Virology , vol.74 , pp. 4174-4182
    • Chang, Y.E.1    Laimins, L.A.2
  • 86
    • 80055107582 scopus 로고    scopus 로고
    • High-risk human papillomaviruses repress constitutive kappa interferon transcription via E6 to prevent pathogen recognition receptor and antiviral-gene expression
    • Reiser J, Hurst J, Voges M, Krauss P, Munch P, et al. (2011) High-risk human papillomaviruses repress constitutive kappa interferon transcription via E6 to prevent pathogen recognition receptor and antiviral-gene expression. Journal of virology 85: 11372-11380.
    • (2011) Journal of Virology , vol.85 , pp. 11372-11380
    • Reiser, J.1    Hurst, J.2    Voges, M.3    Krauss, P.4    Munch, P.5
  • 87
    • 0035047160 scopus 로고    scopus 로고
    • Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NF-kappaB-responsive genes in cervical keratinocytes
    • Nees M, Geoghegan JM, Hyman T, Frank S, Miller L, et al. (2001) Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NF-kappaB-responsive genes in cervical keratinocytes. Journal of virology 75: 4283-4296.
    • (2001) Journal of Virology , vol.75 , pp. 4283-4296
    • Nees, M.1    Geoghegan, J.M.2    Hyman, T.3    Frank, S.4    Miller, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.