-
1
-
-
1642362512
-
Combined tlr and cd40 triggering induces potent cd8+t cell expansion with variable dependence on type i ifn
-
Ahonen CL, Doxsee CL, McGurran SM et al (2004) Combined TLR and CD40 triggering induces potent CD8+T cell expansion with variable dependence on type I IFN. J Exp Med 199:775–784. doi: 10.1084/jem.20031591
-
(2004)
J Exp Med
, vol.199
, pp. 775-784
-
-
Ahonen, C.L.1
Doxsee, C.L.2
McGurran, S.M.3
-
2
-
-
33846039130
-
Antitumor nk activation induced by the toll-like receptor 3-ticam-1 (Trif) pathway in myeloid dendritic cells
-
Akazawa T, Ebihara T, Okuno M et al (2007) Antitumor NK activation induced by the Toll-like receptor 3-TICAM-1 (TRIF) pathway in myeloid dendritic cells. Proc Natl Acad Sci U S A 104:252–257. doi: 10.1073/pnas.0605978104
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 252-257
-
-
Akazawa, T.1
Ebihara, T.2
Okuno, M.3
-
3
-
-
84855817522
-
Immunology in the clinic review series; focus on cancer: Tumour associated macrophages: Undisputed stars of the inflammatory tumour microenvironment
-
Allavena P, Mantovani A (2012) Immunology in the clinic review series; focus on cancer: tumour associated macrophages: undisputed stars of the inflammatory tumour microenvironment. Clin Exp Immunol 167:195–205. doi: 10.1111/j.1365-2249.2011.04515
-
(2012)
Clin Exp Immunol
, vol.167
, pp. 195-205
-
-
Allavena, P.1
Mantovani, A.2
-
4
-
-
0035164478
-
Increased production of immature myeloid cells in cancer patients: A mechanism of immunosuppression in cancer
-
Almand B, Clark JI, Nikitina E et al (2001) Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J Immunol 166:678–689
-
(2001)
J Immunol
, vol.166
, pp. 678-689
-
-
Almand, B.1
Clark, J.I.2
Nikitina, E.3
-
5
-
-
84876271525
-
Cross-priming for antitumor ctl induced by solubleag + polyi:C depends on the ticam-1 pathway in mouse cd11c(+)/cd8α(+) dendritic cells
-
Azuma M, Ebihara T, Oshiumi H et al (2012) Cross-priming for antitumor CTL induced by solubleAg + polyI:C depends on the TICAM-1 pathway in mouse CD11c(+)/CD8α(+) dendritic cells. Oncoimmunology 1:581–592. doi: 10.4161/onci.19893
-
(2012)
Oncoimmunology
, vol.1
, pp. 581-592
-
-
Azuma, M.1
Ebihara, T.2
Oshiumi, H.3
-
6
-
-
77949872871
-
Cancer and inflammation: Implications for pharmacology and therapeutics
-
Balkwill F, Mantovani A (2010) Cancer and inflammation: implications for pharmacology and therapeutics. Clin Pharmacol Ther 87:401–406. doi: 10.1038/clpt.2009.312
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 401-406
-
-
Balkwill, F.1
Mantovani, A.2
-
7
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets:Cancer as a paradigm
-
Biswas SKS, Mantovani AA (2010) Macrophage plasticity and interaction with lymphocyte subsets:cancer as a paradigm. Nat Immunol 11:889–896. doi: 10.1038/ni.1937
-
(2010)
Nat Immunol
, vol.11
, pp. 889-896
-
-
Biswas, S.1
Mantovani, A.A.2
-
8
-
-
0025849163
-
Tumor suppression after tumor-cell targeted tumornecrosis-factor-alpha gene-transfer
-
Blankenstein T, Qin ZH, Uberla K et al (1991) Tumor suppression after tumor-cell targeted tumornecrosis-factor-alpha gene-transfer. J Exp Med 173:1047–1052. doi: 10.1084/jem.173.5.1047
-
(1991)
J Exp Med
, vol.173
, pp. 1047-1052
-
-
Blankenstein, T.1
Qin, Z.H.2
Uberla, K.3
-
9
-
-
77949940198
-
Intracellular toll-like receptors
-
Blasius AL, Beutler B (2010) Intracellular toll-like receptors. Immunity 32:305–315. doi: 10.1016/j.immuni.2010.03.012
-
(2010)
Immunity
, vol.32
, pp. 305-315
-
-
Blasius, A.L.1
Beutler, B.2
-
10
-
-
76649097628
-
Membrane-associated hsp72 from tumor-derived exosomes mediates stat3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells
-
Chalmin F, Ladoire S, Mignot G et al (2010) Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells. J Clin Invest 120:457–471. doi: 10.1172/JCI40483
-
(2010)
J Clin Invest
, vol.120
, pp. 457-471
-
-
Chalmin, F.1
Ladoire, S.2
Mignot, G.3
-
11
-
-
34547469630
-
Macrophage polarization and insulin resistance: Pparγ in control
-
Charo IF (2007) Macrophage polarization and insulin resistance: PPARγ in control. Cell Metab 6:96–98. doi: 10.1016/j.cmet.2007.07.006
-
(2007)
Cell Metab
, vol.6
, pp. 96-98
-
-
Charo, I.F.1
-
12
-
-
53349099219
-
Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by s100a9 protein
-
Cheng P, Corzo CA, Luetteke N et al (2008) Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein. J ExpMed 205:2235–2249. doi: 10.1084/jem.20080132
-
(2008)
J Expmed
, vol.205
, pp. 2235-2249
-
-
Cheng, P.1
Corzo, C.A.2
Luetteke, N.3
-
13
-
-
78650756969
-
Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function
-
Condamine T, Gabrilovich DI (2011) Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function. Trends Immunol 32:19–25. doi: 10.1016/j.it.2010.10.002
-
(2011)
Trends Immunol
, vol.32
, pp. 19-25
-
-
Condamine, T.1
Gabrilovich, D.I.2
-
14
-
-
84863151366
-
Origins of tumor-associated macrophages and neutrophils
-
Cortez-Retamozo V, Etzrodt M, Newton A et al (2012) Origins of tumor-associated macrophages and neutrophils. Proc Natl Acad Sci U S A 109:2491–2496. doi: 10.1073/pnas.1113744109
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 2491-2496
-
-
Cortez-Retamozo, V.1
Etzrodt, M.2
Newton, A.3
-
15
-
-
78149330949
-
Hif-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
-
Corzo CA, Condamine T, Lu L et al (2010) HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment. J Exp Med 207:2439–2453. doi: 10.1084/jem.20100587
-
(2010)
J Exp Med
, vol.207
, pp. 2439-2453
-
-
Corzo, C.A.1
Condamine, T.2
Lu, L.3
-
16
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z (2002) Inflammation and cancer. Nature 420:860–867. doi: 10.1038/nature01322
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
17
-
-
84861787202
-
Dendritic cell-activating vaccine adjuvants differ in the ability to elicit antitumor immunity due to an adjuvant-specific induction of immune suppressive cells
-
Dang Y, Wagner WM, Gad E et al (2012) Dendritic cell-activating vaccine adjuvants differ in the ability to elicit antitumor immunity due to an adjuvant-specific induction of immune suppressive cells. Clin Cancer Res 18:3122–3131. doi: 10.1158/1078-0432.CCR-12-0113
-
(2012)
Clin Cancer Res
, vol.18
, pp. 3122-3131
-
-
Dang, Y.1
Wagner, W.M.2
Gad, E.3
-
18
-
-
84876424760
-
Macrophage regulation of tumor responses to anticancer therapies
-
De Palma M, Lewis CE (2013) Macrophage regulation of tumor responses to anticancer therapies. Cancer Cell 23:277–286. doi: 10.1016/j.ccr.2013.02.013
-
(2013)
Cancer Cell
, vol.23
, pp. 277-286
-
-
De Palma, M.1
Lewis, C.E.2
-
19
-
-
34548644772
-
The histone h3 lysine-27 demethylase jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
-
De Santa F, Totaro MG, Prosperini E et al (2007) The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell 130:1083–1094. doi: 10.1016/j.cell.2007.08.019
-
(2007)
Cell
, vol.130
, pp. 1083-1094
-
-
De Santa, F.1
Totaro, M.G.2
Prosperini, E.3
-
20
-
-
67651160649
-
Cd4(+) t cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
-
DeNardo DG, Barreto JB, Andreu P et al (2009) CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 16:91–102. doi: 10.1016/j.ccr.2009.06.018
-
(2009)
Cancer Cell
, vol.16
, pp. 91-102
-
-
DeNardo, D.G.1
Barreto, J.B.2
Reu, P.3
-
21
-
-
54849440346
-
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy
-
Diaz-Montero CM, Salem ML, Nishimura MI et al (2009) Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy. Cancer Immunol Immunother 58:49–59. doi: 10.1007/s00262-008-0523-4
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 49-59
-
-
Diaz-Montero, C.M.1
Salem, M.L.2
Nishimura, M.I.3
-
22
-
-
75649141166
-
Identification of a polyi: C-inducible membrane protein that participates in dendritic cell-mediated natural killer cell activation
-
Ebihara T, Azuma M, Oshiumi H et al (2010) Identification of a polyI: C-inducible membrane protein that participates in dendritic cell-mediated natural killer cell activation. J Exp Med 207:2675–2687. doi: 10.1084/jem.20091573
-
(2010)
J Exp Med
, vol.207
, pp. 2675-2687
-
-
Ebihara, T.1
Azuma, M.2
Oshiumi, H.3
-
23
-
-
67649208478
-
The endogenous toll-like receptor 4 agonist s100a8/s100a9 (Calprotectin) as innate amplifier of infection, autoimmunity, and cancer
-
Ehrchen JM, Sunderkötter C, Foell D (2009) The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer. J Leukoc Biol 86:557–566. doi: 10.1189/jlb.1008647
-
(2009)
J Leukoc Biol
, vol.86
, pp. 557-566
-
-
Ehrchen, J.M.1
Sunderkötter, C.2
Foell, D.3
-
24
-
-
64849106667
-
Tumor-specific bacteriophages induce tumor destruction through activation of tumor-associated macrophages
-
Eriksson F, Tsagozis P, Lundberg K et al (2009) Tumor-specific bacteriophages induce tumor destruction through activation of tumor-associated macrophages. J Immunol 182(5):3105–3111. doi: 10.4049/jimmunol.0800224
-
(2009)
J Immunol
, vol.182
, Issue.5
, pp. 3105-3111
-
-
Eriksson, F.1
Tsagozis, P.2
Lundberg, K.3
-
25
-
-
34250823515
-
Gene-specific control of inflammation by tlr induced chromatin modifications
-
Foster SL, Hargreaves DC, Medzhitov R (2007) Gene-specific control of inflammation by TLR induced chromatin modifications. Nature 447:972–978. doi: 10.1038/nature05836
-
(2007)
Nature
, vol.447
, pp. 972-978
-
-
Foster, S.L.1
Hargreaves, D.C.2
Medzhitov, R.3
-
26
-
-
33745003285
-
Bacterial lipopolysaccharide induces hif-1 activation in human monocytes via p44/42 mapk and nf-kappab
-
Frede S, Stockmann C, Freitag P, Fandrey J (2006) Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-kappaB. Biochem J 396(3):517–527. doi: 10.1042/BJ20051839
-
(2006)
Biochem J
, vol.396
, Issue.3
, pp. 517-527
-
-
Frede, S.1
Stockmann, C.2
Freitag, P.3
Fandrey, J.4
-
27
-
-
84860484044
-
Tumor-associated neutrophils: Friend or foe?
-
Fridlender ZG, Albelda SM (2012) Tumor-associated neutrophils: friend or foe? Carcinogenesis 33:949–955. doi: 10.1093/carcin/bgs123
-
(2012)
Carcinogenesis
, vol.33
, pp. 949-955
-
-
Fridlender, Z.G.1
Albelda, S.M.2
-
28
-
-
10244279184
-
Mechanisms and functional significance of tumour-induced dendritic-cell defects
-
Gabrilovich D (2004) Mechanisms and functional significance of tumour-induced dendritic-cell defects. Nat Rev Immunol 4:941–952. doi: 10.1038/nri1498
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 941-952
-
-
Gabrilovich, D.1
-
29
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich DI, Nagaraj S (2009) Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 9:162–174. doi: 10.1038/nri2506
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
31
-
-
84884151496
-
Tumor associated macrophages and neutrophils in cancer
-
Galdiero MR, Bonavita E, Barajon I et al (2013) Tumor associated macrophages and neutrophils in cancer. Immunobiology 218:1402–1410. doi: 10.1016/j.imbio.2013.06.003
-
(2013)
Immunobiology
, vol.218
, pp. 1402-1410
-
-
Galdiero, M.R.1
Bonavita, E.2
Barajon, I.3
-
32
-
-
84872801225
-
Trial watch: Experimental toll-like receptor agonists for cancer therapy
-
Galluzzi L, Vacchelli E, Eggermont A et al (2012) Trial watch: experimental Toll-like receptor agonists for cancer therapy. Oncoimmunology 1:699–716. doi: 10.4161/onci.20696
-
(2012)
Oncoimmunology
, vol.1
, pp. 699-716
-
-
Galluzzi, L.1
Vacchelli, E.2
Eggermont, A.3
-
33
-
-
84873597334
-
Role of macrophage targeting in the antitumor activity of trabectedin
-
Germano G, Frapolli R, Belgiovine C et al (2013) Role of macrophage targeting in the antitumor activity of trabectedin. Cancer Cell 23:249–262. doi: 10.1016/j.ccr.2013.01.008
-
(2013)
Cancer Cell
, vol.23
, pp. 249-262
-
-
Germano, G.1
Frapolli, R.2
Belgiovine, C.3
-
34
-
-
79953328298
-
Tumor-associated neutrophils: New targets for cancer therapy
-
Gregory AD, Houghton AM (2011) Tumor-associated neutrophils: new targets for cancer therapy. Cancer Res 71:2411–2416. doi: 10.1158/0008-5472.CAN-10-2583
-
(2011)
Cancer Res
, vol.71
, pp. 2411-2416
-
-
Gregory, A.D.1
Houghton, A.M.2
-
35
-
-
17144398046
-
Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection
-
Guiducci C, Vicari AP, Sangaletti S et al (2005) Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection. Cancer Res 65:3437–3446.
-
(2005)
Cancer Res
, vol.65
, pp. 3437-3446
-
-
Guiducci, C.1
Vicari, A.P.2
Sangaletti, S.3
-
36
-
-
84943421400
-
-
doi: 10.1158/0008-5472.CAN-04-4262
-
-
-
-
37
-
-
45149134605
-
Re-educating tumor-associated macrophages by targeting nf-kappa b
-
Hagemann T, Lawrence T, McNeish I et al (2008) “Re-educating” tumor-associated macrophages by targeting NF-kappa B. J Exp Med 205:1261–1268. doi: 10.1084/jem.20080108
-
(2008)
J Exp Med
, vol.205
, pp. 1261-1268
-
-
Hagemann, T.1
Lawrence, T.2
McNeish, I.3
-
38
-
-
84858590826
-
Accessories to the crime: Functions of cells recruited to the tumor microenvironment
-
Hanahan D, Coussens LM (2012) Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell 21:309–322. doi: 10.1016/j.ccr.2012.02.022
-
(2012)
Cancer Cell
, vol.21
, pp. 309-322
-
-
Hanahan, D.1
Coussens, L.M.2
-
39
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA (2010) Hallmarks of cancer: the next generation. Cell 144:646–674. doi: 10.1016/j.cell.2011.02.013
-
(2010)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
40
-
-
70249140303
-
Myeloid-derived suppressor cells down-regulatel-selectin expression on cd4+ and cd8+t cells
-
Hanson EM, Clements VK, Sinha P et al (2009) Myeloid-derived suppressor cells down-regulateL-selectin expression on CD4+ and CD8+T cells. J Immunol 183:937–944. doi: 10.4049/jimmunol.0804253
-
(2009)
J Immunol
, vol.183
, pp. 937-944
-
-
Hanson, E.M.1
Clements, V.K.2
Sinha, P.3
-
41
-
-
33751504690
-
Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis
-
Hiratsuka S, Watanabe A, Aburatani H, Maru Y (2006) Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nat Cell Biol 8:1369–1375. doi: 10.1038/ncb1507
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1369-1375
-
-
Hiratsuka, S.1
Watanabe, A.2
Aburatani, H.3
Maru, Y.4
-
42
-
-
55549128598
-
The s100a8-serum amyloid a3-tlr4 paracrine cascade establishes a pre-metastatic phase
-
Hiratsuka S, Watanabe A, Sakurai Y et al (2008) The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase. Nat Cell Biol 10:1349–1355. doi: 10.1038/ncb1794
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1349-1355
-
-
Hiratsuka, S.1
Watanabe, A.2
Sakurai, Y.3
-
43
-
-
33748051738
-
Irfs: Master regulators of signalling by toll-like receptors and cytosolic pattern-recognition receptors
-
Honda K, Taniguchi T (2006) IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat Rev Immunol 6:644–658. doi: 10.1038/nri1900
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 644-658
-
-
Honda, K.1
Taniguchi, T.2
-
44
-
-
34547736572
-
Crosstalk among jak-stat, toll-like receptor, and itam-dependent pathways in macrophage activation
-
Hu X, Chen J, Wang L, Ivashkiv LB (2007) Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation. J Leukoc Biol 82:237–243. doi: 10.1189/jlb.1206763
-
(2007)
J Leukoc Biol
, vol.82
, pp. 237-243
-
-
Hu, X.1
Chen, J.2
Wang, L.3
Ivashkiv, L.B.4
-
45
-
-
31544446571
-
Gr-1+cd115+ immature myeloid suppressor cells mediate the development of tumor-induced t regulatory cells and t-cell anergy in tumor-bearing host
-
Huang B, Pan P-Y, Li Q et al (2006) Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res 66:1123–1131. doi: 10.1158/0008-5472.CAN-05-1299
-
(2006)
Cancer Res
, vol.66
, pp. 1123-1131
-
-
Huang, B.1
Pan, P.-Y.2
Li, Q.3
-
46
-
-
34248328368
-
Ccl2/ccr2 pathway mediates recruitment of myeloid suppressor cells to cancers
-
Huang B, Lei Z, Zhao J et al (2007) CCL2/CCR2 pathway mediates recruitment of myeloid suppressor cells to cancers. Cancer Lett 252:86–92. doi: 10.1016/j.canlet.2006.12.012
-
(2007)
Cancer Lett
, vol.252
, pp. 86-92
-
-
Huang, B.1
Lei, Z.2
Zhao, J.3
-
47
-
-
37849035627
-
Tlr signaling by tumor and immune cells: A doubleedged sword
-
Huang B, Zhao J, Unkeless JC et al (2008) TLR signaling by tumor and immune cells: a doubleedged sword. Oncogene 27:218–224. doi: 10.1038/sj.onc.1210904
-
(2008)
Oncogene
, vol.27
, pp. 218-224
-
-
Huang, B.1
Zhao, J.2
Unkeless, J.C.3
-
48
-
-
70350435962
-
Epigenetic regulation of the alternatively activated macrophage phenotype
-
Ishii M, Wen H, Corsa CAS et al (2009) Epigenetic regulation of the alternatively activated macrophage phenotype. Blood 114:3244–3254. doi: 10.1182/blood-2009-04-217620
-
(2009)
Blood
, vol.114
, pp. 3244-3254
-
-
Ishii, M.1
Wen, H.2
Corsa, C.3
-
49
-
-
74549167783
-
Regulation of adaptive immunity by the innate immune system
-
Iwasaki A, Medzhitov R (2010) Regulation of adaptive immunity by the innate immune system. Science 327:291–295. doi: 10.1126/science.1183021
-
(2010)
Science
, vol.327
, pp. 291-295
-
-
Iwasaki, A.1
Medzhitov, R.2
-
50
-
-
84883820837
-
Putting the brakes on anticancer therapies: Suppression of innate immune pathways by tumor-associated myeloid cells
-
Jinushi M, Yagita H, Yoshiyama H, Tahara H (2013) Putting the brakes on anticancer therapies: suppression of innate immune pathways by tumor-associated myeloid cells. Trends Mol Med 19:536–545. doi: 10.1016/j.molmed.2013.06.001
-
(2013)
Trends Mol Med
, vol.19
, pp. 536-545
-
-
Jinushi, M.1
Yagita, H.2
Yoshiyama, H.3
Tahara, H.4
-
51
-
-
84878414390
-
Tlr agonists: Our best frenemy in cancer immunotherapy
-
Kaczanowska S, Joseph AM, Davila E (2013) TLR agonists: our best frenemy in cancer immunotherapy. J Leukoc Biol 93:847–863. doi: 10.1189/jlb.1012501
-
(2013)
J Leukoc Biol
, vol.93
, pp. 847-863
-
-
Kaczanowska, S.1
Joseph, A.M.2
Davila, E.3
-
52
-
-
79956300649
-
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
-
Kawai T, Akira S (2011) Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34:637–650. doi: 10.1016/j.immuni.2011.05.006
-
(2011)
Immunity
, vol.34
, pp. 637-650
-
-
Kawai, T.1
Akira, S.2
-
53
-
-
79952282422
-
The significant role of mast cells in cancer
-
Khazaie K, Blatner NR, Khan MW et al (2011) The significant role of mast cells in cancer. Cancer Metastasis Rev 30:45–60. doi: 10.1007/s10555-011-9286
-
(2011)
Cancer Metastasis Rev
, vol.30
, pp. 45-60
-
-
Khazaie, K.1
Blatner, N.R.2
Khan, M.W.3
-
54
-
-
58149269348
-
Carcinoma-produced factors activate myeloid cells through tlr2 to stimulate metastasis
-
Kim S, Takahashi H, Lin W-W et al (2009) Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis. Nature 457:102–106. doi: 10.1038/nature07623
-
(2009)
Nature
, vol.457
, pp. 102-106
-
-
Kim, S.1
Takahashi, H.2
Lin, W.-W.3
-
55
-
-
28644445445
-
Inhibiting stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
-
Kortylewski M, Kujawski M, Wang T et al (2005) Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nat Med 11:1314–1321. doi: 10.1038/nm1325
-
(2005)
Nat Med
, vol.11
, pp. 1314-1321
-
-
Kortylewski, M.1
Kujawski, M.2
Wang, T.3
-
56
-
-
79951671510
-
Irf5 promotes inflammatory macrophage polarization and th1-th17 responses
-
Krausgruber T, Blazek K, Smallie T et al (2011) IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses. Nat Immunol 12:231–238. doi: 10.1038/ni.1990
-
(2011)
Nat Immunol
, vol.12
, pp. 231-238
-
-
Krausgruber, T.1
Blazek, K.2
Smallie, T.3
-
57
-
-
80355146399
-
Transcriptional regulation of macrophage polarization: Enabling diversity with identity
-
Lawrence T, Natoli G (2011) Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat Rev Immunol 11:750–761. doi: 10.1038/nri3088
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 750-761
-
-
Lawrence, T.1
Natoli, G.2
-
58
-
-
74349124255
-
Toll-like receptor 4 signaling promotes tumor growth
-
Lee C-H, Wu C-L, Shiau A-L (2010) Toll-like receptor 4 signaling promotes tumor growth. J Immunother 33:73–82. doi: 10.1097/CJI.0b013e3181b7a0a4
-
(2010)
J Immunother
, vol.33
, pp. 73-82
-
-
Lee, C.-H.1
Wu, C.-L.2
Shiau, A.-L.3
-
59
-
-
31544441610
-
Distinct role of macrophages in different tumor microenvironments
-
Lewis CE, Pollard JW (2006) Distinct role of macrophages in different tumor microenvironments. Cancer Res 66:605–612. doi: 10.1158/0008-5472.CAN-05-4005
-
(2006)
Cancer Res
, vol.66
, pp. 605-612
-
-
Lewis, C.E.1
Pollard, J.W.2
-
60
-
-
59849126377
-
Cancer-expanded myeloid-derived suppressor cells induce anergy of nk cells through membrane-bound tgf-beta 1
-
Li H, Han Y, Guo Q et al (2009) Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1. J Immunol 182:240–249
-
(2009)
J Immunol
, vol.182
, pp. 240-249
-
-
Li, H.1
Han, Y.2
Guo, Q.3
-
61
-
-
34347226359
-
Tumor-associated macrophages press the angiogenic switch in breast cancer
-
Lin EY, Pollard JW (2007) Tumor-associated macrophages press the angiogenic switch in breast cancer. Cancer Res. doi: 10.1158/0008-5472.CAN-07-0912
-
(2007)
Cancer Res
-
-
Lin, E.Y.1
Pollard, J.W.2
-
62
-
-
0035911221
-
Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy
-
Lin EY, Nguyen AV, Russell RG, Pollard JW (2001) Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med 193:727–739. doi: 10.1084/jem.193.6.727
-
(2001)
J Exp Med
, vol.193
, pp. 727-739
-
-
Lin, E.Y.1
Nguyen, A.V.2
Russell, R.G.3
Pollard, J.W.4
-
63
-
-
84879663836
-
M2-polarized tumor-associated macrophages promoted epithelial-mesenchymal transition in pancreatic cancer cells, partially through tlr4/il-10 signaling pathway
-
Liu C-Y, Xu J-Y, Shi X-Y et al (2013) M2-polarized tumor-associated macrophages promoted epithelial-mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway. Lab Invest 93:844–854. doi: 10.1038/labinvest.2013.69
-
(2013)
Lab Invest
, vol.93
, pp. 844-854
-
-
Liu, C.-Y.1
Xu, J.-Y.2
Shi, X.-Y.3
-
64
-
-
80053421470
-
Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic t cells in mice
-
Lu T, Ramakrishnan R, Altiok S et al (2011) Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice. J Clin Invest 121:4015–4029. doi: 10.1172/JCI45862
-
(2011)
J Clin Invest
, vol.121
, pp. 4015-4029
-
-
Lu, T.1
Ramakrishnan, R.2
Altiok, S.3
-
65
-
-
77952937103
-
The m1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time
-
Ma J, Liu L, Che G et al (2010) The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time. BMC Cancer 10:112. doi: 10.1186/1471-2407-10-112
-
(2010)
BMC Cancer
, vol.10
, pp. 112
-
-
Ma, J.1
Liu, L.2
Che, G.3
-
66
-
-
79952772423
-
Paired immunoglobin-like receptor-b regulates the suppressive function and fate of myeloid-derived suppressor cells
-
Ma G, Pan P-Y, Eisenstein S et al (2011) Paired immunoglobin-like receptor-B regulates the suppressive function and fate of myeloid-derived suppressor cells. Immunity 34:385–395. doi: 10.1016/j.immuni.2011.02.004
-
(2011)
Immunity
, vol.34
, pp. 385-395
-
-
Ma, G.1
Pan, P.-Y.2
Eisenstein, S.3
-
67
-
-
0036839143
-
Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized m2 mononuclear phagocytes
-
Mantovani A, Sozzani S, Locati M et al (2002) Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23:549–555
-
(2002)
Trends Immunol
, vol.23
, pp. 549-555
-
-
Mantovani, A.1
Sozzani, S.2
Locati, M.3
-
69
-
-
41149119143
-
Tumor‐induced tolerance and immune suppression by myeloid derived suppressor cells
-
Marigo I, Dolcetti L, Serafi ni P et al (2008) Tumor‐induced tolerance and immune suppression by myeloid derived suppressor cells. Immunol Rev 222:162–179. doi: 10.1111/j.1600-065X.2008.00602
-
(2008)
Immunol Rev
, vol.222
, pp. 162-179
-
-
Marigo, I.1
Dolcetti, L.2
Serafi Ni, P.3
-
70
-
-
54549109936
-
Modulation of the antitumor immune response by complement
-
Markiewski MM, DeAngelis RA, Benencia F et al (2008) Modulation of the antitumor immune response by complement. Nat Immunol 9:1225–1235. doi: 10.1038/ni.1655
-
(2008)
Nat Immunol
, vol.9
, pp. 1225-1235
-
-
Markiewski, M.M.1
DeAngelis, R.A.2
Benencia, F.3
-
71
-
-
79953750307
-
Targeting the ang2/tie2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells
-
Mazzieri R, Pucci F, Moi D et al (2011) Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells. Cancer Cell 19:512–526. doi: 10.1016/j.ccr.2011.02.005
-
(2011)
Cancer Cell
, vol.19
, pp. 512-526
-
-
Mazzieri, R.1
Pucci, F.2
Moi, D.3
-
72
-
-
73949135474
-
Distinct and complementary functions of mda5 and tlr3 in poly(I:C)-mediated activation of mouse nk cells
-
McCartney S, Vermi W, Gilfillan S et al (2009) Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells. J Exp Med 206:2967–2976. doi: 10.1084/jem.20091181
-
(2009)
J Exp Med
, vol.206
, pp. 2967-2976
-
-
McCartney, S.1
Vermi, W.2
Gilfillan, S.3
-
73
-
-
43249130187
-
Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct t cell-suppressive activity
-
Movahedi K, Guilliams M, Van den Bossche J et al (2008) Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity. Blood 111:4233–4244. doi: 10.1182/blood-2007-07-099226
-
(2008)
Blood
, vol.111
, pp. 4233-4244
-
-
Movahedi, K.1
Guilliams, M.2
Van Den Bossche, J.3
-
75
-
-
34447118098
-
Altered recognition of antigen is a mechanism of cd8+t cell tolerance in cancer
-
Nagaraj S, Gupta K, Pisarev V et al (2007) Altered recognition of antigen is a mechanism of CD8+T cell tolerance in cancer. Nat Med 13:828–835. doi: 10.1038/nm1609
-
(2007)
Nat Med
, vol.13
, pp. 828-835
-
-
Nagaraj, S.1
Gupta, K.2
Pisarev, V.3
-
76
-
-
58949086448
-
Mononuclear myeloid-derived “suppressor” cells express rae-1 and activate natural killer cells
-
Nausch N, Galani IE, Schlecker E, Cerwenka A (2008) Mononuclear myeloid-derived “suppressor” cells express RAE-1 and activate natural killer cells. Blood 112:4080–4089. doi: 10.1182/blood-2008-03-143776
-
(2008)
Blood
, vol.112
, pp. 4080-4089
-
-
Nausch, N.1
Galani, I.E.2
Schlecker, E.3
Cerwenka, A.4
-
77
-
-
27144538568
-
Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus activated kinase 2/signal transducers and activators of transcription 3 pathway
-
Nefedova Y, Nagaraj S, Rosenbauer A et al (2005) Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus activated kinase 2/signal transducers and activators of transcription 3 pathway. Cancer Res 65:9525–9535. doi: 10.1158/0008-5472.CAN-05-0529
-
(2005)
Cancer Res
, vol.65
, pp. 9525-9535
-
-
Nefedova, Y.1
Nagaraj, S.2
Rosenbauer, A.3
-
78
-
-
33947590063
-
Whatever turns you on: Accessory-cell-dependent activation of nkcells by pathogens
-
Newman KC, Riley EM (2007) Whatever turns you on: accessory-cell-dependent activation of NKcells by pathogens. Nat Rev Immunol 7:279–291. doi: 10.1038/nri2057
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 279-291
-
-
Newman, K.C.1
Riley, E.M.2
-
79
-
-
0037320451
-
Ticam-1, an adaptor molecule that participates in toll-like receptor 3-mediated interferon-beta induction
-
Oshiumi H, Matsumoto M, Funami K et al (2003) TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction. Nat Immunol 4:161–167.doi: 10.1038/ni886
-
(2003)
Nat Immunol
, vol.4
, pp. 161-167
-
-
Oshiumi, H.1
Matsumoto, M.2
Funami, K.3
-
80
-
-
65249138393
-
Myeloid-derived suppressor cells: Linking inflammation and cancer
-
Ostrand-Rosenberg S, Sinha P (2009) Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol 182:4499–4506. doi: 10.4049/jimmunol.0802740
-
(2009)
J Immunol
, vol.182
, pp. 4499-4506
-
-
Ostrand-Rosenberg, S.1
Sinha, P.2
-
81
-
-
84875364025
-
Inhibition of tgf-β signaling in combination with tlr7 ligation re-programs a tumoricidal phenotype in tumor-associated macrophages
-
H. Shime et al. Peng J, Tsang JYS, Li D et al (2013) Inhibition of TGF-β signaling in combination with TLR7 ligation re-programs a tumoricidal phenotype in tumor-associated macrophages. Cancer Lett 331:239–249. doi: 10.1016/j.canlet.2013.01.001
-
(2013)
Cancer Lett
, vol.331
, pp. 239-249
-
-
Shime, H.1
Peng, J.2
Tsang, J.3
Li, D.4
-
82
-
-
77951258918
-
Myeloid-derived suppressor cell heterogeneity and subset definition
-
Peranzoni E, Zilio S, Marigo I et al (2010) Myeloid-derived suppressor cell heterogeneity and subset definition. Curr Opin Immunol 22:238–244. doi: 10.1016/j.coi.2010.01.021
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 238-244
-
-
Peranzoni, E.1
Zilio, S.2
Marigo, I.3
-
83
-
-
77950950894
-
Macrophage diversity enhances tumor progression and metastasis
-
Qian BZ, Pollard JW (2010) Macrophage diversity enhances tumor progression and metastasis. Cell 141:39–51. doi: 10.1016/j.cell.2010.03.014
-
(2010)
Cell
, vol.141
, pp. 39-51
-
-
Qian, B.Z.1
Pollard, J.W.2
-
84
-
-
84887444879
-
Microenvironmental regulation of tumor progression and metastasis
-
Quail DF, Joyce JA (2013) Microenvironmental regulation of tumor progression and metastasis. Nat Med 19:1423–1437. doi: 10.1038/nm.3394
-
(2013)
Nat Med
, vol.19
, pp. 1423-1437
-
-
Quail, D.F.1
Joyce, J.A.2
-
85
-
-
34447296425
-
Regulation of spontaneous intestinal tumorigenesis through the adaptor protein myd88
-
Rakoff-Nahoum S, Medzhitov R (2007) Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science 317:124–127. doi: 10.1126/science.1140488
-
(2007)
Science
, vol.317
, pp. 124-127
-
-
Rakoff-Nahoum, S.1
Medzhitov, R.2
-
87
-
-
80054075147
-
Tumour macrophages as potential targets of bisphosphonates
-
Rogers TL, Holen I (2011) Tumour macrophages as potential targets of bisphosphonates. J Transl Med 9:177. doi: 10.1186/1479-5876-9-177
-
(2011)
J Transl Med
, vol.9
, pp. 177
-
-
Rogers, T.L.1
Holen, I.2
-
88
-
-
84875511757
-
Tumor necrosis factor-α blocks differentiation and enhances suppressive activity of immature myeloid cells during chronic inflammation
-
Sade-Feldman M, Kanterman J, Ish-Shalom E et al (2013) Tumor necrosis factor-α blocks differentiation and enhances suppressive activity of immature myeloid cells during chronic inflammation. Immunity 38:541–554. doi: 10.1016/j.immuni.2013.02.007
-
(2013)
Immunity
, vol.38
, pp. 541-554
-
-
Sade-Feldman, M.1
Kanterman, J.2
Ish-Shalom, E.3
-
89
-
-
77956954197
-
The jmjd3-irf4 axis regulates m2 macrophage polarization and host responses against helminth infection
-
Satoh T, Takeuchi O, Vandenbon A et al (2010) The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. Nat Immunol 11:936–944. doi: 10.1038/ni.1920
-
(2010)
Nat Immunol
, vol.11
, pp. 936-944
-
-
Satoh, T.1
Takeuchi, O.2
Vandenbon, A.3
-
90
-
-
47049126742
-
Chemokine-mediated rapid turnover of myeloidderived suppressor cells in tumor-bearing mice
-
Sawanobori Y, Ueha S, Kurachi M et al (2008) Chemokine-mediated rapid turnover of myeloidderived suppressor cells in tumor-bearing mice. Blood 111:5457–5466. doi: 10.1182/blood-2008-01-136895
-
(2008)
Blood
, vol.111
, pp. 5457-5466
-
-
Sawanobori, Y.1
Ueha, S.2
Kurachi, M.3
-
91
-
-
79958696667
-
Receptor tyrosine kinases and tlr/il1rs unexpectedly activate myeloid cell pi3kγ, a single convergent point promoting tumor inflammation and progression
-
Schmid MC, Avraamides CJ, Dippold HC et al (2011) Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3kγ, a single convergent point promoting tumor inflammation and progression. Cancer Cell 19:715–727. doi: 10.1016/j.ccr.2011.04.016
-
(2011)
Cancer Cell
, vol.19
, pp. 715-727
-
-
Schmid, M.C.1
Avraamides, C.J.2
Dippold, H.C.3
-
92
-
-
48549085973
-
Myeloid-derived suppressor cells promote cross-tolerance in b-cell lymphoma by expanding regulatory t cells
-
Serafi ni P, Mgebroff S, Noonan K, Borrello I (2008) Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells. Cancer Res 68:5439–5449. doi: 10.1158/0008-5472.CAN-07-6621
-
(2008)
Cancer Res
, vol.68
, pp. 5439-5449
-
-
Serafi Ni, P.1
Mgebroff, S.2
Noonan, K.3
Borrello, I.4
-
93
-
-
75649100153
-
Pattern recognition receptors of innate immunity and their application to tumor immunotherapy
-
Seya T, Shime H, Ebihara T et al (2010) Pattern recognition receptors of innate immunity and their application to tumor immunotherapy. Cancer Sci 101:313–320.doi: 10.1111/j.1349-7006.2009.01442
-
(2010)
Cancer Sci
, vol.101
, pp. 313-320
-
-
Seya, T.1
Shime, H.2
Ebihara, T.3
-
94
-
-
84880865534
-
Tamable tumor-associated macrophages in response to innate rna sensing
-
Seya T, Shime H, Matsumoto M (2012) TAMable tumor-associated macrophages in response to innate RNA sensing. Oncoimmunology 1:1000–1001. doi: 10.4161/onci.19894
-
(2012)
Oncoimmunology
, vol.1
, pp. 1000-1001
-
-
Seya, T.1
Shime, H.2
Matsumoto, M.3
-
95
-
-
33646896173
-
Antitumor activity of the tlr-5 ligand flagellin in mouse models of cancer
-
Sfondrini L, Rossini A, Besusso D et al (2006) Antitumor activity of the TLR-5 ligand flagellin in mouse models of cancer. J Immunol 176:6624–6630
-
(2006)
J Immunol
, vol.176
, pp. 6624-6630
-
-
Sfondrini, L.1
Rossini, A.2
Besusso, D.3
-
96
-
-
84857136783
-
Toll-like receptor 3 signaling converts tumor supporting myeloid cells to tumoricidal effectors
-
Shime H, Matsumoto M, Oshiumi H et al (2012) Toll-like receptor 3 signaling converts tumor supporting myeloid cells to tumoricidal effectors. Proc Natl Acad Sci U S A 109:2066–2071. doi: 10.1073/pnas.1113099109
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 2066-2071
-
-
Shime, H.1
Matsumoto, M.2
Oshiumi, H.3
-
97
-
-
84898597440
-
Myeloid-derived suppressor cells confer tumor suppressive functions on natural killer cells via polyinosinic: Polycytidylic acid treatment in mouse tumor models
-
Shime H, Kojima A, Maruyama A et al (2014) Myeloid-derived suppressor cells confer tumor suppressive functions on natural killer cells via polyinosinic: polycytidylic acid treatment in mouse tumor models. J Innate Immun 6:293–305. doi: 10.1159/000355126
-
(2014)
J Innate Immun
, vol.6
, pp. 293-305
-
-
Shime, H.1
Kojima, A.2
Maruyama, A.3
-
98
-
-
84856824651
-
Intratumoral injection of cpg oligonucleotides induces the differentiation and reduces the immunosuppressive activity of myeloid-derived suppressor cells
-
Shirota Y, Shirota H, Klinman DM (2012) Intratumoral injection of CpG oligonucleotides induces the differentiation and reduces the immunosuppressive activity of myeloid-derived suppressor cells. J Immunol 188:1592–1599. doi: 10.4049/jimmunol.1101304
-
(2012)
J Immunol
, vol.188
, pp. 1592-1599
-
-
Shirota, Y.1
Shirota, H.2
Klinman, D.M.3
-
99
-
-
36849013036
-
Bv8 regulates myeloid-cell-dependent tumour angiogenesis
-
Shojaei F, Wu X, Zhong C et al (2007) Bv8 regulates myeloid-cell-dependent tumour angiogenesis. Nature 450:825–831. doi: 10.1038/nature06348
-
(2007)
Nature
, vol.450
, pp. 825-831
-
-
Shojaei, F.1
Wu, X.2
Zhong, C.3
-
100
-
-
48449097002
-
Role of myeloid cells in tumor angiogenesis and growth
-
Shojaei F, Zhong C, Wu X et al (2008) Role of myeloid cells in tumor angiogenesis and growth. Trends Cell Biol 18:372–378. doi: 10.1016/j.tcb.2008.06.003
-
(2008)
Trends Cell Biol
, vol.18
, pp. 372-378
-
-
Shojaei, F.1
Zhong, C.2
Wu, X.3
-
101
-
-
77957735624
-
Role of tumour-associated macrophages in cancer-related inflammation
-
Sica A (2010) Role of tumour-associated macrophages in cancer-related inflammation. Exp Oncol 32:153–158
-
(2010)
Exp Oncol
, vol.32
, pp. 153-158
-
-
Sica, A.1
-
102
-
-
84857883847
-
Macrophage plasticity and polarization: In vivo veritas
-
Sica A, Mantovani A (2012) Macrophage plasticity and polarization: in vivo veritas. J Clin Invest 122:787–795. doi: 10.1172/JCI59643
-
(2012)
J Clin Invest
, vol.122
, pp. 787-795
-
-
Sica, A.1
Mantovani, A.2
-
103
-
-
53349125963
-
Pro inflammatory s100 proteins regulate the accumulation of myeloid-derived suppressor cells
-
Sinha P, Okoro C, Foell D et al (2008) Pro inflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells. J Immunol 181:4666–4675. doi: 10.4049/jimmunol.181.7.4666
-
(2008)
J Immunol
, vol.181
, pp. 4666-4675
-
-
Sinha, P.1
Okoro, C.2
Foell, D.3
-
104
-
-
70350728931
-
Tumor-associated macrophages (Tam) as major players of the cancer-related inflammation
-
Solinas G, Germano G, Mantovani A, Allavena P (2009) Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation. J Leukoc Biol 86:1065–1073. doi: 10.1189/jlb.0609385
-
(2009)
J Leukoc Biol
, vol.86
, pp. 1065-1073
-
-
Solinas, G.1
Germano, G.2
Mantovani, A.3
Allavena, P.4
-
105
-
-
79953113052
-
Transcription factors in myeloid-derived suppressor cell recruitment and function
-
Sonda N, Chioda M, Zilio S et al (2011) Transcription factors in myeloid-derived suppressor cell recruitment and function. Curr Opin Immunol 23:279–285. doi: 10.1016/j.coi.2010.12.006
-
(2011)
Curr Opin Immunol
, vol.23
, pp. 279-285
-
-
Sonda, N.1
Chioda, M.2
Zilio, S.3
-
106
-
-
84872794136
-
Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization
-
Spence S, Fitzsimons A, Boyd CR et al (2013) Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization. Immunity 38:66–78. doi: 10.1016/j.immuni.2012.09.013
-
(2013)
Immunity
, vol.38
, pp. 66-78
-
-
Spence, S.1
Fitzsimons, A.2
Boyd, C.R.3
-
107
-
-
83555164774
-
S100a8 and s100a9: New insights into their roles in malignancy
-
Srikrishna G (2011) S100A8 and S100A9: new insights into their roles in malignancy. J InnateImmun 4:31–40. doi: 10.1159/000330095
-
(2011)
J Innateimmun
, vol.4
, pp. 31-40
-
-
Srikrishna, G.1
-
108
-
-
75149123468
-
Myeloid-derived suppressor cells inhibit t-cell activation by depleting cystine and cysteine
-
Srivastava MK, Sinha P, Clements VK et al (2010) Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine. Cancer Res 70:68–77. doi: 10.1158/0008-5472.CAN-09-2587
-
(2010)
Cancer Res
, vol.70
, pp. 68-77
-
-
Srivastava, M.K.1
Sinha, P.2
Clements, V.K.3
-
109
-
-
84863991235
-
Myeloid suppressor cell depletion augments antitumor activity in lung cancer
-
Srivastava MK, Zhu L, Harris-White M et al (2012) Myeloid suppressor cell depletion augments antitumor activity in lung cancer. PLoS ONE 7:e40677. doi: 10.1371/journal.pone.0040677
-
(2012)
Plos ONE
, vol.7
-
-
Srivastava, M.K.1
Zhu, L.2
Harris-White, M.3
-
110
-
-
77949345555
-
Tumor-associated macrophages and survival in classichodgkin’s lymphoma
-
Steidl C, Lee T, Shah SP et al (2010) Tumor-associated macrophages and survival in classicHodgkin’s lymphoma. N Engl J Med 362:875–885. doi: 10.1056/NEJMoa0905680
-
(2010)
N Engl J Med
, vol.362
, pp. 875-885
-
-
Steidl, C.1
Lee, T.2
Shah, S.P.3
-
111
-
-
84884556145
-
History of myeloid-derived suppressor cells
-
Talmadge JE, Gabrilovich DI (2013) History of myeloid-derived suppressor cells. Nat Rev Cancer 13:739–752. doi: 10.1038/nrc3581
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 739-752
-
-
Talmadge, J.E.1
Gabrilovich, D.I.2
-
112
-
-
0036222241
-
Tlr4, but not tlr2, mediates ifn-β–inducedstat1α/β-dependent gene expression in macrophages
-
Toshchakov V, Jones BW, Perera P-Y et al (2002) TLR4, but not TLR2, mediates IFN-β–inducedSTAT1α/β-dependent gene expression in macrophages. Nat Immunol 3:392–398. doi: 10.1038/ni774
-
(2002)
Nat Immunol
, vol.3
, pp. 392-398
-
-
Toshchakov, V.1
Jones, B.W.2
Perera, P.-Y.3
-
113
-
-
68849128500
-
Therapeutic targeting of myeloid-derived suppressor cells
-
Ugel S, Delpozzo F, Desantis G et al (2009) Therapeutic targeting of myeloid-derived suppressor cells. Curr Opin Pharmacol 9:470–481. doi: 10.1016/j.coph.2009.06.014
-
(2009)
Curr Opin Pharmacol
, vol.9
, pp. 470-481
-
-
Ugel, S.1
Delpozzo, F.2
Desantis, G.3
-
114
-
-
84858760109
-
Combining immunotherapy and targeted therapies in cancer treatment
-
Vanneman M, Dranoff G (2012) Combining immunotherapy and targeted therapies in cancer treatment. Nat Rev Cancer 12:237–251. doi: 10.1038/nrc3237
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 237-251
-
-
Vanneman, M.1
Dranoff, G.2
-
115
-
-
84875866083
-
Stat3 regulates arginase-i in myeloid-derived suppressor cells from cancer patients
-
Vasquez-Dunddel D, Pan F, Zeng Q et al (2013) STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients. J Clin Invest 123:1580–1589. doi: 10.1172/JCI60083
-
(2013)
J Clin Invest
, vol.123
, pp. 1580-1589
-
-
Vasquez-Dunddel, D.1
Pan, F.2
Zeng, Q.3
-
116
-
-
84885029080
-
Myeloid-derived suppressor cell development is regulated by a stat/irf-8 axis
-
Waight JD, Netherby C, Hensen ML et al (2013) Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis. J Clin Invest 123:4464–4478. doi: 10.1172/JCI68189
-
(2013)
J Clin Invest
, vol.123
, pp. 4464-4478
-
-
Waight, J.D.1
Netherby, C.2
Hensen, M.L.3
-
117
-
-
37849014248
-
Toll-like receptors and immune regulation: Implications for cancer therapy
-
Wang R-F, Miyahara Y, Wang HY (2008) Toll-like receptors and immune regulation: implications for cancer therapy. Oncogene 27:181–189. doi: 10.1038/sj.onc.1210906
-
(2008)
Oncogene
, vol.27
, pp. 181-189
-
-
Wang, R.-F.1
Miyahara, Y.2
Wang, H.Y.3
-
118
-
-
77953752609
-
Notch signaling determines the m1 versus m2 polarization of macrophages in antitumor immune responses
-
Wang Y-C, He F, Feng F et al (2010) Notch signaling determines the M1 versus M2 polarization of macrophages in antitumor immune responses. Cancer Res 70:4840–4849. doi: 10.1158/0008-5472.CAN-10-0269
-
(2010)
Cancer Res
, vol.70
, pp. 4840-4849
-
-
Wang, Y.-C.1
He, F.2
Feng, F.3
-
119
-
-
84862591151
-
Notch-rbp-j signaling regulates the transcription factor irf8 to promote inflammatory macrophage polarization
-
Xu H, Zhu J, Smith S et al (2012) Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization. Nat Immunol 13:642–650. doi: 10.1038/ni.2304
-
(2012)
Nat Immunol
, vol.13
, pp. 642-650
-
-
Xu, H.1
Zhu, J.2
Smith, S.3
-
120
-
-
0043176281
-
Role of adaptor trif in the myd88-independent toll-like receptor signaling pathway
-
Yamamoto M, Sato S, Hemmi H et al (2003) Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 301:640–643. doi: 10.1126/science.1087262
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
-
121
-
-
84877990693
-
Polarization and reprogramming of myeloid-derived suppressor cells
-
Yang W-C, Ma G, Chen S-H, Pan P-Y (2013) Polarization and reprogramming of myeloid-derived suppressor cells. J Mol Cell Biol 5:207–209. doi: 10.1093/jmcb/mjt009
-
(2013)
J Mol Cell Biol
, vol.5
, pp. 207-209
-
-
Yang, W.-C.1
Ma, G.2
Chen, S.-H.3
Pan, P.-Y.4
-
122
-
-
54049134747
-
Subsets of myeloid-derived suppressor cells in tumor-bearing mice
-
Youn J-I, Nagaraj S, Collazo M, Gabrilovich DI (2008) Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol 181:5791–5802
-
(2008)
J Immunol
, vol.181
, pp. 5791-5802
-
-
Youn, J.-I.1
Nagaraj, S.2
Collazo, M.3
Gabrilovich, D.I.4
-
123
-
-
85027923251
-
Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer
-
Youn J-I, Kumar V, Collazo M et al (2013) Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer. Nat Immunol 14:211–220. doi: 10.1038/ni.2526
-
(2013)
Nat Immunol
, vol.14
, pp. 211-220
-
-
Youn, J.-I.1
Kumar, V.2
Collazo, M.3
-
124
-
-
33845865825
-
Crosstalk between cancer and immune cells: Role of stat3 in the tumour microenvironment
-
Yu H, Kortylewski M, Pardoll D (2007) Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev Immunol 7:41–51. doi: 10.1038/nri1995
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 41-51
-
-
Yu, H.1
Kortylewski, M.2
Pardoll, D.3
-
125
-
-
20244367914
-
Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: A mechanism of tumor evasion
-
Zea AH, Rodriguez PC, Atkins MB et al (2005) Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion. Cancer Res 65:3044–3048. doi: 10.1158/0008-5472.CAN-04-4505
-
(2005)
Cancer Res
, vol.65
, pp. 3044-3048
-
-
Zea, A.H.1
Rodriguez, P.C.2
Atkins, M.B.3
-
126
-
-
34249274905
-
Tumor necrosis factor receptor 2-mediated tumor suppression is nitric oxide dependent and involves angiostasis
-
Zhao X, Mohaupt M, Jiang J et al (2007) Tumor necrosis factor receptor 2-mediated tumor suppression is nitric oxide dependent and involves angiostasis. Cancer Res 67:4443–4450. doi: 10.1158/0008-5472.CAN-07-0185
-
(2007)
Cancer Res
, vol.67
, pp. 4443-4450
-
-
Zhao, X.1
Mohaupt, M.2
Jiang, J.3
-
127
-
-
84868629269
-
Tnf signaling drives myeloid-derived suppressor cell accumulation
-
Zhao X, Rong L, Zhao X et al (2012) TNF signaling drives myeloid-derived suppressor cell accumulation. J Clin Invest 122:4094–4104. doi: 10.1172/JCI64115
-
(2012)
J Clin Invest
, vol.122
, pp. 4094-4104
-
-
Zhao, X.1
Rong, L.2
Zhao, X.3
-
128
-
-
33748987908
-
Cancer despite immunosurveillance: Immunoselection and immunosubversion
-
Zitvogel L, Tesniere A, Kroemer G (2006) Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat Rev Immunol 6:715–727. doi: 10.1038/nri1936
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 715-727
-
-
Zitvogel, L.1
Tesniere, A.2
Kroemer, G.3
-
129
-
-
79953300942
-
Cpg blocks immunosuppression by myeloidderived suppressor cells in tumor-bearing mice
-
Zoglmeier C, Bauer H, Nörenberg D et al (2011) CpG blocks immunosuppression by myeloidderived suppressor cells in tumor-bearing mice. Clin Cancer Res 17:1765–1775. doi: 10.1158/1078-0432.CCR-10-2672
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1765-1775
-
-
Zoglmeier, C.1
Bauer, H.2
Nörenberg, D.3
|