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Volumn 124, Issue 18, 1997, Pages 3493-3500

Ulnaless (Ul), a regulatory mutation inducing both loss-of-function and gain-of-function of posterior Hoxd genes

Author keywords

HoxD; Limb development; Mouse; Ulnaless

Indexed keywords

HOMEODOMAIN PROTEIN; TRANSCRIPTION FACTOR;

EID: 1842290333     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (115)

References (35)
  • 1
    • 0028802421 scopus 로고
    • Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of fgf-4 and shh in the limb bud
    • Chan, D. C., A., Wynshaw-Boris, A. and Leder, P. (1995) Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of fgf-4 and shh in the limb bud. Development 121, 3151-3161.
    • (1995) Development , vol.121 , pp. 3151-3161
    • Chan, D.C.A.1    Wynshaw-Boris, A.2    Leder, P.3
  • 2
    • 0028085623 scopus 로고
    • Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of Hoxd-11
    • Davis, A. P. and Capecchi, M. R. (1994). Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of Hoxd-11. Development 120, 2187-2148.
    • (1994) Development , vol.120 , pp. 2187-12148
    • Davis, A.P.1    Capecchi, M.R.2
  • 3
    • 0029963585 scopus 로고    scopus 로고
    • A mutational analysis of the 5′ HoxD genes: Dissection of genetic interactions during limb development in the mouse
    • Davis, A. P. and Capecchi, M. R. (1996). A mutational analysis of the 5′ HoxD genes: Dissection of genetic interactions during limb development in the mouse. Development 122, 1175-1185.
    • (1996) Development , vol.122 , pp. 1175-1185
    • Davis, A.P.1    Capecchi, M.R.2
  • 4
    • 0029026767 scopus 로고
    • Absence of radius and ulna in mice lacking Hoxa-11 and Hoxd-11
    • Davis, A. P., Witte, D. P., Hsieh-Li, H. M., Potter, S. S. and Capecchi, M. R. (1995). Absence of radius and ulna in mice lacking Hoxa-11 and Hoxd-11. Nature 375, 791-795.
    • (1995) Nature , vol.375 , pp. 791-795
    • Davis, A.P.1    Witte, D.P.2    Hsieh-Li, H.M.3    Potter, S.S.4    Capecchi, M.R.5
  • 5
    • 0025052670 scopus 로고
    • The mouse mutation Ulnaless on chromosome 2
    • Davisson, M. T. and Cattanach, B. M. (1990). The mouse mutation Ulnaless on chromosome 2. J. Hered. 81, 151-153.
    • (1990) J. Hered. , vol.81 , pp. 151-153
    • Davisson, M.T.1    Cattanach, B.M.2
  • 6
    • 0027358721 scopus 로고
    • Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs
    • Dollé, P., Dierich, A., LeMeur, M., Schimmang, T., Schuhbaur, B., Chambon, P. and Duboule, D. (1993). Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs. Cell 75, 431-441.
    • (1993) Cell , vol.75 , pp. 431-441
    • Dollé, P.1    Dierich, A.2    LeMeur, M.3    Schimmang, T.4    Schuhbaur, B.5    Chambon, P.6    Duboule, D.7
  • 7
    • 0024358805 scopus 로고
    • Two gene members of the murine HOX-5 complex show regional and cell-type specific expression in developing limbs and gonads
    • Dollé, P. and Duboule, D. (1989). Two gene members of the murine HOX-5 complex show regional and cell-type specific expression in developing limbs and gonads. EMBO J. 8, 1507-15.
    • (1989) EMBO J. , vol.8 , pp. 1507-1515
    • Dollé, P.1    Duboule, D.2
  • 9
    • 0026326323 scopus 로고
    • The Hox-4.8 gene is localized at the 5′ extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development
    • Dollé, P., Izpisúa-Belmonte, J.-C., Boneinelli, E. and Duboule, D. (1991b). The Hox-4.8 gene is localized at the 5′ extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development. Mech. Dev. 36, 3-13.
    • (1991) Mech. Dev. , vol.36 , pp. 3-13
    • Dollé, P.1    Izpisúa-Belmonte, J.-C.2    Boneinelli, E.3    Duboule, D.4
  • 10
    • 0026200238 scopus 로고
    • Patterning in the vertebrate limb
    • Duboule, D. (1991). Patterning in the vertebrate limb. Curr. Opin. Genet. Dev. 1, 211-6.
    • (1991) Curr. Opin. Genet. Dev. , vol.1 , pp. 211-216
    • Duboule, D.1
  • 11
    • 0027932522 scopus 로고
    • Colinearity and functional hierarchy among genes of the homeotic complexes
    • Duboule, D. and Morata, G. (1994). Colinearity and functional hierarchy among genes of the homeotic complexes. Trends Genet. 10, 358-364.
    • (1994) Trends Genet. , vol.10 , pp. 358-364
    • Duboule, D.1    Morata, G.2
  • 12
    • 0028921493 scopus 로고
    • Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice
    • Favier, B., Le Meur, M., Chambon, P. and Dollé, P. (1995). Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice. Proc. Natl. Acad. Sci. USA 92, 310-314.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 310-314
    • Favier, B.1    Le Meur, M.2    Chambon, P.3    Dollé, P.4
  • 16
    • 0029748544 scopus 로고    scopus 로고
    • In vivo targeting of a regulatory element required for positioning the Hoxd-11 and Hoxd-10 expression boundaries
    • Gérard, M., Chen, J.-Y., Gronemeyer, H., Chambon, P., Duboule, D. and Zákány, J. (1996) In vivo targeting of a regulatory element required for positioning the Hoxd-11 and Hoxd-10 expression boundaries. Genes Dev. 18, 2326-2334.
    • (1996) Genes Dev. , vol.18 , pp. 2326-2334
    • Gérard, M.1    Chen, J.-Y.2    Gronemeyer, H.3    Chambon, P.4    Duboule, D.5    Zákány, J.6
  • 17
    • 0031043604 scopus 로고    scopus 로고
    • Analysis of Hoxd-13 and Hoxd-11 misexpression in chicken limb buds reveals that Hox genes affect both bone condensation and growth
    • Goff, D. J. and Tabin, C. J. (1997). Analysis of Hoxd-13 and Hoxd-11 misexpression in chicken limb buds reveals that Hox genes affect both bone condensation and growth. Development 124, 627-636.
    • (1997) Development , vol.124 , pp. 627-636
    • Goff, D.J.1    Tabin, C.J.2
  • 18
    • 0029589439 scopus 로고
    • The limb deformity mutation disrupts the SHH/FGF-4 feedback loop and regulation of 5′ HoxD genes during limb pattern formation
    • Haramis, A. G., Brown, J. M. and Zeller, R. (1995). The limb deformity mutation disrupts the SHH/FGF-4 feedback loop and regulation of 5′ HoxD genes during limb pattern formation. Development 121, 4237-4245.
    • (1995) Development , vol.121 , pp. 4237-4245
    • Haramis, A.G.1    Brown, J.M.2    Zeller, R.3
  • 19
    • 0025785350 scopus 로고
    • Murine genes related to the Drosophila AbdB homeotic genes are sequentially expressed during development of the posterior part of the body
    • Izpisúa-Belmonte, J.-C., Falkenstein, H., Dollé, P., Renucci, A. and Duboule, D. (1991). Murine genes related to the Drosophila AbdB homeotic genes are sequentially expressed during development of the posterior part of the body. EMBO J. 10, 2279-2289.
    • (1991) EMBO J. , vol.10 , pp. 2279-2289
    • Izpisúa-Belmonte, J.-C.1    Falkenstein, H.2    Dollé, P.3    Renucci, A.4    Duboule, D.5
  • 20
    • 0029835646 scopus 로고    scopus 로고
    • Function of posterior HoxD genes in the morphogenesis of the anal sphincter
    • Kondo, T., Dollé, P., Zákány, J. and Duboule, D. (1996). Function of posterior HoxD genes in the morphogenesis of the anal sphincter. Development 122, 2651-2659.
    • (1996) Development , vol.122 , pp. 2651-2659
    • Kondo, T.1    Dollé, P.2    Zákány, J.3    Duboule, D.4
  • 21
    • 0031020325 scopus 로고    scopus 로고
    • Limb deformity proteins: Role in mesodermal induction of the apical ectodermal ridge
    • Kuhlman, J. and Niswander, L. (1997). Limb deformity proteins: role in mesodermal induction of the apical ectodermal ridge. Development 124, 133-139.
    • (1997) Development , vol.124 , pp. 133-139
    • Kuhlman, J.1    Niswander, L.2
  • 23
    • 0031050961 scopus 로고    scopus 로고
    • Mutation of HOXA13 in hand-foot-genital syndrome
    • Mortlock, D. P. and Innis, J. W. (1997). Mutation of HOXA13 in hand-foot-genital syndrome. Nature Genet. 15, 179-180.
    • (1997) Nature Genet. , vol.15 , pp. 179-180
    • Mortlock, D.P.1    Innis, J.W.2
  • 24
    • 0030002141 scopus 로고    scopus 로고
    • The molecular basis of hypodactyly (Hd): A deletion in Hoxa13 leads to arrest of digital arch formation
    • Mortlock, D. P., Post, L. C. and Innis, J. W. (1996). The molecular basis of hypodactyly (Hd): A deletion in Hoxa13 leads to arrest of digital arch formation. Nature Genet. 13, 284-289.
    • (1996) Nature Genet. , vol.13 , pp. 284-289
    • Mortlock, D.P.1    Post, L.C.2    Innis, J.W.3
  • 25
    • 0029132035 scopus 로고
    • Fibroblast-growth-factor receptor mutations in human skeletal disorders
    • Muenke, M. and Schell, U. (1995). Fibroblast-growth-factor receptor mutations in human skeletal disorders. Trends Genet. 11, 308-313.
    • (1995) Trends Genet. , vol.11 , pp. 308-313
    • Muenke, M.1    Schell, U.2
  • 26
    • 0029871929 scopus 로고    scopus 로고
    • Altered growth and branching patterns in synpolydactyly caused by mutations in HOXD13
    • Muragaki, Y., Mundlos, S., Upton, J. and Olsen, B. R. (1996). Altered growth and branching patterns in synpolydactyly caused by mutations in HOXD13. Science 272, 548-551.
    • (1996) Science , vol.272 , pp. 548-551
    • Muragaki, Y.1    Mundlos, S.2    Upton, J.3    Olsen, B.R.4
  • 27
    • 0030482663 scopus 로고    scopus 로고
    • Genetic and physical mapping of the mouse Ulnaless locus
    • Peichel, C. L., Abbott, C. M. and Vogt, T. F. (1996). Genetic and physical mapping of the mouse Ulnaless locus. Genetics 144, 1757-1767.
    • (1996) Genetics , vol.144 , pp. 1757-1767
    • Peichel, C.L.1    Abbott, C.M.2    Vogt, T.F.3
  • 28
    • 0030782384 scopus 로고    scopus 로고
    • The mouse Ulnaless mutation deregulates posterior Hoxd gene colinearity and alters appendicular patterning
    • Peichel, C. L., Prabhakaran, B. and Vogt, T. K. (1997). The mouse Ulnaless mutation deregulates posterior Hoxd gene colinearity and alters appendicular patterning. Development 124, 3481-3492.
    • (1997) Development , vol.124 , pp. 3481-3492
    • Peichel, C.L.1    Prabhakaran, B.2    Vogt, T.K.3
  • 29
    • 0027131262 scopus 로고
    • Homeotic transformation and limb defects in Hoxa-11 mutant mice
    • Small, K. M. and Potter, S. S. (1993). Homeotic transformation and limb defects in Hoxa-11 mutant mice. Genes Dev. 7, 2318-2328.
    • (1993) Genes Dev. , vol.7 , pp. 2318-2328
    • Small, K.M.1    Potter, S.S.2
  • 30
    • 0030604724 scopus 로고    scopus 로고
    • Gene transpositions in the HoxD complex reveal a hierarchy of regulatory controls
    • van der Hoeven, F., Zákány, J. and Duboule, D. (1996). Gene transpositions in the HoxD complex reveal a hierarchy of regulatory controls. Cell 85, 1025-1035.
    • (1996) Cell , vol.85 , pp. 1025-1035
    • Van der Hoeven, F.1    Zákány, J.2    Duboule, D.3
  • 31
    • 0025007616 scopus 로고
    • 'Formins': Proteins deduced from the alternative transcripts of the limb deformity gene
    • Woychik, R. P., Maas, R. L., Zeller, R., Vogt, T. F. and Leder, P. (1990) 'Formins': Proteins deduced from the alternative transcripts of the limb deformity gene. Nature 346, 850-853.
    • (1990) Nature , vol.346 , pp. 850-853
    • Woychik, R.P.1    Maas, R.L.2    Zeller, R.3    Vogt, T.F.4    Leder, P.5
  • 32
    • 0029118414 scopus 로고
    • Fibroblast growth factors in mammalian development
    • Yamaguchi, T. P. and Rossant, J. (1995). Fibroblast growth factors in mammalian development. Cur. Opin. Gen. and Dev. 5, 485-491.
    • (1995) Cur. Opin. Gen. and Dev. , vol.5 , pp. 485-491
    • Yamaguchi, T.P.1    Rossant, J.2
  • 33
    • 0028973404 scopus 로고
    • Misexpression of Hoxa-13 induces cartilage homeotic transformation and changes cell adhesiveness in chick limb buds
    • Yokouchi, Y., Nakazato, S., Yamamoto, M., Goto, Y., Kameda, T., Iba, H. and Kuroiwa, A. (1995). Misexpression of Hoxa-13 induces cartilage homeotic transformation and changes cell adhesiveness in chick limb buds. Genes Dev. 9, 2509-2522.
    • (1995) Genes Dev. , vol.9 , pp. 2509-2522
    • Yokouchi, Y.1    Nakazato, S.2    Yamamoto, M.3    Goto, Y.4    Kameda, T.5    Iba, H.6    Kuroiwa, A.7
  • 34
    • 0029854152 scopus 로고    scopus 로고
    • Synpolydactyly in mice with a targeted deficiency in the HoxD complex
    • Zákány, J. and Duboule, D. (1996). Synpolydactyly in mice with a targeted deficiency in the HoxD complex. Nature 384, 69-71.
    • (1996) Nature , vol.384 , pp. 69-71
    • Zákány, J.1    Duboule, D.2
  • 35
    • 0342872062 scopus 로고    scopus 로고
    • Deletion of a HoxD enhancer induces transcriptional heterochrony leading to transposition of the sacrum
    • in press
    • Zákány, J., Gérard, M., Favier, B. and Duboule, D. (1997) Deletion of a HoxD enhancer induces transcriptional heterochrony leading to transposition of the sacrum. EMBO J., in press.
    • (1997) EMBO J.
    • Zákány, J.1    Gérard, M.2    Favier, B.3    Duboule, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.