The Small-Molecule TrkB Agonist 7, 8-Dihydroxyflavone Decreases Hippocampal Newborn Neuron Death after Traumatic Brain Injury

Journal of Neuropathology and Experimental Neurology

Volumn 74, Issue 6, 2015, Pages 557-567

  Chen, Liang ^b   Gao, Xiang ^a   Zhao, Shu ^b   Hu, Weipeng ^c   Chen, Jinhui ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

7,8 dihydroxyflavone; Brain derived neurotrophic factor; Cell death; Neuroprotection; Newborn neuron; Traumatic brain injury

Indexed keywords

7,8 DIHYDROXYFLAVONE; BRAIN DERIVED NEUROTROPHIC FACTOR; TYROSINE RELATED KINASE B; UNCLASSIFIED DRUG; 6,7-DIHYDROXYFLAVONE; ANA 12 COMPOUND; AZEPINE DERIVATIVE; BENZAMIDE DERIVATIVE; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; FLAVONE DERIVATIVE; FLUORESCEIN DERIVATIVE; FLUORO JADE; NERVE PROTEIN; NEUROPROTECTIVE AGENT;

ANIMAL EXPERIMENT; ARTICLE; EXCITOTOXICITY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MOUSE; NERVE CELL NECROSIS; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRAUMATIC BRAIN INJURY; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN INJURIES; C57BL MOUSE; CELL DEATH; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; NERVE CELL; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, NEWBORN; AZEPINES; BENZAMIDES; BRAIN INJURIES; CELL DEATH; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONES; FLUORESCEINS; HIPPOCAMPUS; IN VITRO TECHNIQUES; MALE; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; PHOSPHORYLATION; RECEPTOR, TRKB; SIGNAL TRANSDUCTION;

EID: 84942850743     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/NEN.0000000000000199     Document Type: Article

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