메뉴 건너뛰기




Volumn 31, Issue 4, 2012, Pages 765-778

Activation of TrkB by 7,8-dihydroxyflavone prevents fear memory defects and facilitates amygdalar synaptic plasticity in aging

Author keywords

7,8 dihydroxyflavone; aging; learning and memory; synaptic plasticity; TrkB

Indexed keywords

7,8 DIHYDROXYFLAVONE; BRAIN DERIVED NEUROTROPHIC FACTOR;

EID: 84866336983     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2012-120886     Document Type: Article
Times cited : (62)

References (65)
  • 1
    • 77950229880 scopus 로고    scopus 로고
    • Neural mechanisms of ageing and cognitive decline
    • Bishop NA, Lu T, Yankner BA (2010) Neural mechanisms of ageing and cognitive decline. Nature 464, 529-535.
    • (2010) Nature , vol.464 , pp. 529-535
    • Bishop, N.A.1    Lu, T.2    Yankner, B.A.3
  • 2
    • 0042861455 scopus 로고    scopus 로고
    • Small-conductance, Ca2+-acivated k+ channel SK3 generates age-related memory and LTP deficits
    • Blank T, Nijholt I, Kye MJ, Radulovic J, Spiess J (2003) Small-conductance, Ca2+-acivated k+ channel SK3 generates age-related memory and LTP deficits. Nat Neurosci 6, 911-912.
    • (2003) Nat Neurosci , vol.6 , pp. 911-912
    • Blank, T.1    Nijholt, I.2    Kye, M.J.3    Radulovic, J.4    Spiess, J.5
  • 4
    • 9644253002 scopus 로고    scopus 로고
    • Fischer 344 rats display age-related memory deficits in trace fear conditioning
    • Villarreal JS, Dykes JR, Barea-Rodriguez EJ (2004) Fischer 344 rats display age-related memory deficits in trace fear conditioning. Behav Neurosci 118, 1166-1175.
    • (2004) Behav Neurosci , vol.118 , pp. 1166-1175
    • Villarreal, J.S.1    Dykes, J.R.2    Barea-Rodriguez, E.J.3
  • 5
    • 26944442371 scopus 로고    scopus 로고
    • Improvement of memory for context by inhibition of caspase-1 in aged rats
    • Gemma C, Fister M, Hudson C, Bickford PC (2005) Improvement of memory for context by inhibition of caspase-1 in aged rats. Eur J Neurosci 22, 1751-1756.
    • (2005) Eur J Neurosci , vol.22 , pp. 1751-1756
    • Gemma, C.1    Fister, M.2    Hudson, C.3    Bickford, P.C.4
  • 6
    • 27644566364 scopus 로고    scopus 로고
    • Age-related deficits in the retention of memories for cued fear conditioning are reversed by galantamine treatment
    • Gould TJ, Feiro OR (2005) Age-related deficits in the retention of memories for cued fear conditioning are reversed by galantamine treatment. Behav Brain Res 165, 160-171.
    • (2005) Behav Brain Res , vol.165 , pp. 160-171
    • Gould, T.J.1    Feiro, O.R.2
  • 7
    • 33745883312 scopus 로고    scopus 로고
    • Impaired trace and contextual fear conditioning in aged rats
    • Moyer JR Jr, Brown TH (2006) Impaired trace and contextual fear conditioning in aged rats. Behav Neurosci 120, 612-624.
    • (2006) Behav Neurosci , vol.120 , pp. 612-624
    • Moyer Jr., J.R.1    Brown, T.H.2
  • 9
    • 66349124196 scopus 로고    scopus 로고
    • Memory deficits are associated with impaired ability to modulate neuronal excitability in middle-aged mice
    • Kaczorowski CC, Disterhoft JF (2009) Memory deficits are associated with impaired ability to modulate neuronal excitability in middle-aged mice. Learn Mem 16, 362-366.
    • (2009) Learn Mem , vol.16 , pp. 362-366
    • Kaczorowski, C.C.1    Disterhoft, J.F.2
  • 10
    • 84861904057 scopus 로고    scopus 로고
    • Aging redistributes medial prefrontal neuronal excitability and impedes extinction of trace fear conditioning
    • Kaczorowski CC, Davis SJ, Moyer JR Jr (2012) Aging redistributes medial prefrontal neuronal excitability and impedes extinction of trace fear conditioning. Neurobiol Aging 33, 1744-1757.
    • (2012) Neurobiol Aging , vol.33 , pp. 1744-1757
    • Kaczorowski, C.C.1    Davis, S.J.2    Moyer Jr., J.R.3
  • 11
    • 84857590013 scopus 로고    scopus 로고
    • Context processing in aging: Older mice are impaired in renewal of extinguished fear
    • Sanders MJ (2011) Context processing in aging: Older mice are impaired in renewal of extinguished fear. Exp Aging Res 37, 572-594.
    • (2011) Exp Aging Res , vol.37 , pp. 572-594
    • Sanders, M.J.1
  • 12
    • 20444392780 scopus 로고    scopus 로고
    • Depression in the elderly
    • AlexopoulosGS(2005) Depression in the elderly. Lancet 365, 1961-1970.
    • (2005) Lancet , vol.365 , pp. 1961-1970
    • Alexopoulos, G.S.1
  • 13
    • 0032125414 scopus 로고    scopus 로고
    • Mechanisms of emotional arousal and lasting declarative memory
    • Cahill L, McGaugh JL (1998) Mechanisms of emotional arousal and lasting declarative memory. Trends Neurosci 21, 294-299.
    • (1998) Trends Neurosci , vol.21 , pp. 294-299
    • Cahill, L.1    McGaugh, J.L.2
  • 14
    • 0033969570 scopus 로고    scopus 로고
    • Memory: A century of consolidation
    • McGaugh JL (2000) Memory: A century of consolidation. Science 287, 248-251.
    • (2000) Science , vol.287 , pp. 248-251
    • McGaugh, J.L.1
  • 15
    • 0036924839 scopus 로고    scopus 로고
    • Morphological alterations in the amygdala and hippocampus of mice during aging
    • von Bohlen und Halbach O, Unsicker K (2002) Morphological alterations in the amygdala and hippocampus of mice during aging. Eur J Neurosci 16, 2434-2440.
    • (2002) Eur J Neurosci , vol.16 , pp. 2434-2440
    • Von, B.1    Halbach, O.2    Unsicker, K.3
  • 16
    • 0031471239 scopus 로고    scopus 로고
    • Fear conditioning induces associative long-term potentiation in the amygdala
    • Rogan MT, Staubli UV, LeDoux JE (1997) Fear conditioning induces associative long-term potentiation in the amygdala. Nature 390, 604-607.
    • (1997) Nature , vol.390 , pp. 604-607
    • Rogan, M.T.1    Staubli, U.V.2    Ledoux, J.E.3
  • 17
    • 0036433355 scopus 로고    scopus 로고
    • Long-term potentiation as a substrate for memory: Evidence from studies of amygdaloid plasticity and Pavlovian fear conditioning
    • Goosens KA, Maren S (2002) Long-term potentiation as a substrate for memory: Evidence from studies of amygdaloid plasticity and Pavlovian fear conditioning. Hippocampus 12, 592-599.
    • (2002) Hippocampus , vol.12 , pp. 592-599
    • Goosens, K.A.1    Maren, S.2
  • 18
    • 10044289749 scopus 로고    scopus 로고
    • Differential regulation of brain-derived neurotrophic factor transcripts during the consolidation of fear learning
    • Rattiner LM, Davis M, Ressler KJ (2004a) Differential regulation of brain-derived neurotrophic factor transcripts during the consolidation of fear learning. Learn Mem 11, 727-731.
    • (2004) Learn Mem , vol.11 , pp. 727-731
    • Rattiner, L.M.1    Davis, M.2    Ressler, K.J.3
  • 19
    • 22844449978 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in amygdala-dependent learning
    • Rattiner LM, Davis M, Ressler KJ (2005) Brain-derived neurotrophic factor in amygdala-dependent learning. Neuroscientist 11, 323-333.
    • (2005) Neuroscientist , vol.11 , pp. 323-333
    • Rattiner, L.M.1    Davis, M.2    Ressler, K.J.3
  • 20
    • 70349102143 scopus 로고    scopus 로고
    • Dopamine is necessary for cue-dependent fear conditioning
    • Fadok JP, Dickerson TM, Palmiter RD (2009) Dopamine is necessary for cue-dependent fear conditioning. J Neurosci 29, 11089-11097.
    • (2009) J Neurosci , vol.29 , pp. 11089-11097
    • Fadok, J.P.1    Dickerson, T.M.2    Palmiter, R.D.3
  • 21
    • 77952349119 scopus 로고    scopus 로고
    • Brainderived neurotrophic factor: A dynamic gatekeeper of neural plasticity
    • Cowansage KK, LeDoux JE, Monfils MH (2010) Brainderived neurotrophic factor: A dynamic gatekeeper of neural plasticity. Curr Mol Pharmacol 3, 12-29.
    • (2010) Curr Mol Pharmacol , vol.3 , pp. 12-29
    • Cowansage, K.K.1    Ledoux, J.E.2    Monfils, M.H.3
  • 22
    • 80054705607 scopus 로고    scopus 로고
    • Synergistic activation of dopamine D1 and TrkB receptors mediate gain control of synaptic plasticity in the basolateral amygdala
    • Li C, Dabrowska J, Hazra R, Rainnie DG (2011) Synergistic activation of dopamine D1 and TrkB receptors mediate gain control of synaptic plasticity in the basolateral amygdala. PLoS One 6, e26065.
    • (2011) PLoS One , vol.6
    • Li, C.1    Dabrowska, J.2    Hazra, R.3    Rainnie, D.G.4
  • 23
    • 80155157843 scopus 로고    scopus 로고
    • Molecular mechanisms of fear learning and memory
    • Johansen JP, Cain CK, Ostroff LE, LeDoux JE (2011) Molecular mechanisms of fear learning and memory. Cell 147, 509-524.
    • (2011) Cell , vol.147 , pp. 509-524
    • Johansen, J.P.1    Cain, C.K.2    Ostroff, L.E.3    Ledoux, J.E.4
  • 24
    • 0037119177 scopus 로고    scopus 로고
    • Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets
    • Karege F, Schwald M, CisseM(2002) Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets. Neurosci Lett 328, 261-264.
    • (2002) Neurosci Lett , vol.328 , pp. 261-264
    • Karege, F.1    Schwald, M.2    Cisse, M.3
  • 26
    • 17044369611 scopus 로고    scopus 로고
    • Age-related changes in brain-derived neurotrophic factor and tyrosine kinase receptor isoforms in the hippocampus and hypothalamus in male rats
    • Silhol M, Bonnichon V, Rage F, Tapia-Arancibia L (2005) Age-related changes in brain-derived neurotrophic factor and tyrosine kinase receptor isoforms in the hippocampus and hypothalamus in male rats. Neuroscience 132, 613-624.
    • (2005) Neuroscience , vol.132 , pp. 613-624
    • Silhol, M.1    Bonnichon, V.2    Rage, F.3    Tapia-Arancibia, L.4
  • 27
    • 83055185674 scopus 로고    scopus 로고
    • Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging
    • Zeng Y, Tan M, Kohyama J, Sneddon M, Watson J, Sun Y, Xie CW (2011) Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging. J Neurosci 31, 17800-17810.
    • (2011) J Neurosci , vol.31 , pp. 17800-17810
    • Zeng, Y.1    Tan, M.2    Kohyama, J.3    Sneddon, M.4    Watson, J.5    Sun, Y.6    Xie, C.W.7
  • 28
    • 70450221663 scopus 로고    scopus 로고
    • Flavonoids and cognition: The molecular mechanisms underlying their behavioural effects
    • Spencer JP, Vauzour D, Rendeiro C (2009) Flavonoids and cognition: The molecular mechanisms underlying their behavioural effects. Arch Biochem Biophys 492, 1-9.
    • (2009) Arch Biochem Biophys , vol.492 , pp. 1-9
    • Spencer, J.P.1    Vauzour, D.2    Rendeiro, C.3
  • 32
    • 84857208654 scopus 로고    scopus 로고
    • 78-dihydroxyflavone a TrkB receptor agonist blocks long-term spatial memory impairment caused by immobilization stress in rats
    • Andero, Daviu N, Escorihuela RM, Nadal R, Armario A (2010) 7,8-dihydroxyflavone, a TrkB receptor agonist, blocks long-term spatial memory impairment caused by immobilization stress in rats. Hippocampus 22, 399-408.
    • (2010) Hippocampus , vol.22 , pp. 399-408
    • Andero Daviu, N.1    Escorihuela, R.M.2    Nadal, R.3    Armario, A.4
  • 33
    • 79952728977 scopus 로고    scopus 로고
    • Effect of 7,8 dihydroxyflavone, a small-molecule TrkB agonist, on emotional learning
    • Andero R, Heldt SA, Ye K, Liu X, Armario A, Ressler KJ (2011) Effect of 7,8 dihydroxyflavone, a small-molecule TrkB agonist, on emotional learning.AmJ Psychiatry 168, 163-172.
    • (2011) AmJ Psychiatry , vol.168 , pp. 163-172
    • Andero, R.1    Heldt, S.A.2    Ye, K.3    Liu, X.4    Armario, A.5    Ressler, K.J.6
  • 34
    • 77957272505 scopus 로고    scopus 로고
    • Neurotrophins enhance CaMKII activity and rescue amyloid-induced deficits in hippocampal synaptic plasticity
    • Zeng Y, Zhao D, Xie CW (2010) Neurotrophins enhance CaMKII activity and rescue amyloid-induced deficits in hippocampal synaptic plasticity. J Alzheimers Dis 21, 823-831.
    • (2010) J Alzheimers Dis , vol.21 , pp. 823-831
    • Zeng, Y.1    Zhao, D.2    Xie, C.W.3
  • 35
    • 0025407386 scopus 로고
    • The lateral amygdaloid nucleus: Sensory interface of the amygdala in fear conditioning
    • LeDoux JE, Cicchetti P, Xagoraris A, Romanski LM (1990) The lateral amygdaloid nucleus: Sensory interface of the amygdala in fear conditioning. J Neurosci 10, 1062-1069.
    • (1990) J Neurosci , vol.10 , pp. 1062-1069
    • Ledoux, J.E.1    Cicchetti, P.2    Xagoraris, A.3    Romanski, L.M.4
  • 36
    • 0026514823 scopus 로고
    • Modality-specific retrograde amnesia of fear
    • Kim JJ, Fanselow MS (1992) Modality-specific retrograde amnesia of fear. Science 256, 675-677.
    • (1992) Science , vol.256 , pp. 675-677
    • Kim, J.J.1    Fanselow, M.S.2
  • 37
    • 0026540012 scopus 로고
    • Equipotentiality of thalamo-amygdala and thalamo-cortico-amygdala circuits in auditory fear conditioning
    • Romanski LM, LeDoux JE (1992) Equipotentiality of thalamo-amygdala and thalamo-cortico-amygdala circuits in auditory fear conditioning. J Neurosci 12, 4501-4509.
    • (1992) J Neurosci , vol.12 , pp. 4501-4509
    • Romanski, L.M.1    Ledoux, J.E.2
  • 38
    • 0028958944 scopus 로고
    • Involvement of the central nucleus and basolateral complex of the amygdala in fear conditioning measured with fear-potentiated startle in rats trained concurrently with auditory and visual conditioned stimuli
    • Campeau S, Davis M (1995) Involvement of the central nucleus and basolateral complex of the amygdala in fear conditioning measured with fear-potentiated startle in rats trained concurrently with auditory and visual conditioned stimuli. J Neurosci 15, 2301-2311.
    • (1995) J Neurosci , vol.15 , pp. 2301-2311
    • Campeau, S.1    Davis, M.2
  • 39
    • 0030699445 scopus 로고    scopus 로고
    • Neurotoxic lesions of the dorsal hippocampus and pavlovian fear conditioning in rats
    • Maren S, Aharonov G, Fanselow MS (1997) Neurotoxic lesions of the dorsal hippocampus and pavlovian fear conditioning in rats. Behav Brain Res 88, 261-274.
    • (1997) Behav Brain Res , vol.88 , pp. 261-274
    • Maren, S.1    Aharonov, G.2    Fanselow, M.S.3
  • 40
    • 84856202981 scopus 로고    scopus 로고
    • Neural mechanisms underlying the conditioned diminution of the unconditioned fear response
    • Wood KH, Ver Hoef LW, Knight DC (2011) Neural mechanisms underlying the conditioned diminution of the unconditioned fear response. Neuroimage 60, 787-799.
    • (2011) Neuroimage , vol.60 , pp. 787-799
    • Wood, K.H.1    Ver Hoef, L.W.2    Knight, D.C.3
  • 41
    • 30944458206 scopus 로고    scopus 로고
    • Regulation of amygdaladependent learning by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol-3-kinase
    • Ou LC, Gean PW (2006) Regulation of amygdaladependent learning by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol-3-kinase. Neuropsychopharmacology 31, 287-296.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 287-296
    • Ou, L.C.1    Gean, P.W.2
  • 42
    • 34547170079 scopus 로고    scopus 로고
    • Transcriptional regulation of brain-derived neurotrophic factor in the amygdala during consolidation of fear memory
    • Ou LC, Gean PW (2007) Transcriptional regulation of brain-derived neurotrophic factor in the amygdala during consolidation of fear memory. Mol Pharmacol 72, 350-358.
    • (2007) Mol Pharmacol , vol.72 , pp. 350-358
    • Ou, L.C.1    Gean, P.W.2
  • 43
    • 77950691765 scopus 로고    scopus 로고
    • Late expression of brainderived neurotrophic factor in the amygdala is required for persistence of fear memory
    • Ou LC, Yeh SH, Gean PW (2010) Late expression of brainderived neurotrophic factor in the amygdala is required for persistence of fear memory. Neurobiol Learn Mem 93, 372-382.
    • (2010) Neurobiol Learn Mem , vol.93 , pp. 372-382
    • Ou, L.C.1    Yeh, S.H.2    Gean, P.W.3
  • 44
    • 33745883312 scopus 로고    scopus 로고
    • Impaired trace and contextual fear conditioning in aged rats
    • Moyer JR Jr, Brown TH (2006) Impaired trace and contextual fear conditioning in aged rats. Behav Neurosci 120, 612-624.
    • (2006) Behav Neurosci , vol.120 , pp. 612-624
    • Moyer Jr., J.R.1    Brown, T.H.2
  • 45
    • 0038491473 scopus 로고    scopus 로고
    • Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics
    • Liu RL, Liu IY, Bi XN, Thompson RF, Doctrow SR, Malfroy B, Baudry M (2003) Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics. Proc Natl Acad Sci U S A 100, 8526-8531.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8526-8531
    • Liu, R.L.1    Liu, I.Y.2    Bi, X.N.3    Thompson, R.F.4    Doctrow, S.R.5    Malfroy, B.6    Baudry, M.7
  • 46
    • 66349124196 scopus 로고    scopus 로고
    • Memory deficits are associated with impaired ability to modulate neuronal excitability in middle-aged mice
    • Kaczorowski CC, Disterhoft JF (2009) Memory deficits are associated with impaired ability to modulate neuronal excitability in middle-aged mice. Learn Mem 16, 362-366.
    • (2009) Learn Mem , vol.16 , pp. 362-366
    • Kaczorowski, C.C.1    Disterhoft, J.F.2
  • 47
    • 79959581845 scopus 로고    scopus 로고
    • Mechanisms underlying basal and learning-related intrinsic excitability in a mouse model of Alzheimer's disease
    • Kaczorowski CC, Sametsky E, Shah S, Vassar R, Disterhoft JF (2011) Mechanisms underlying basal and learning-related intrinsic excitability in a mouse model of Alzheimer's disease. Neurobiol Aging 32, 1452-1465.
    • (2011) Neurobiol Aging , vol.32 , pp. 1452-1465
    • Kaczorowski, C.C.1    Sametsky, E.2    Shah, S.3    Vassar, R.4    Disterhoft, J.F.5
  • 48
    • 0342409469 scopus 로고    scopus 로고
    • Age-related modifications of contextual information processing in rats: Role of emotional reactivity, arousal and testing procedure
    • Doyere V, Gisquet-Verrier P, de Marsanich B, Ammassari-Teule M (2000) Age-related modifications of contextual information processing in rats: Role of emotional reactivity, arousal and testing procedure. Behav Brain Res 114, 153-165.
    • (2000) Behav Brain Res , vol.114 , pp. 153-165
    • Doyere, V.1    Gisquet-Verrier, P.2    De Marsanich, B.3    Ammassari-Teule, M.4
  • 50
    • 0034331242 scopus 로고    scopus 로고
    • Activation of ERK/MAP kinase in the amygdala is required for memory consolidation of pavlovian fear conditioning
    • Schafe GE, Atkins CM, Swank MW, Bauer EP, Sweatt JD, LeDoux JE (2000) Activation of ERK/MAP kinase in the amygdala is required for memory consolidation of pavlovian fear conditioning. J Neurosci 20, 8177-8187.
    • (2000) J Neurosci , vol.20 , pp. 8177-8187
    • Schafe, G.E.1    Atkins, C.M.2    Swank, M.W.3    Bauer, E.P.4    Sweatt, J.D.5    Ledoux, J.E.6
  • 51
    • 68849094397 scopus 로고    scopus 로고
    • TrkB modulates fear learning and amygdalar synaptic plasticity by specific docking sites
    • Musumeci G, Sciarretta C, Rodr'iguez-Moreno A, Al Banchaabouchi M, Negrete-D'iaz V, Costanzi M, Berno V, Egorov AV, von Bohlen Und Halbach O, Cestari V, Delgado-Garc'ia JM, Minichiello L (2009) TrkB modulates fear learning and amygdalar synaptic plasticity by specific docking sites. J Neurosci 29, 10131-10143.
    • (2009) J Neurosci , vol.29 , pp. 10131-10143
    • Musumeci, G.1    Sciarretta, C.2
  • 52
    • 0025407386 scopus 로고
    • The lateral amygdaloid nucleus: Sensory interface of the amygdala in fear conditioning
    • LeDoux JE, Cicchetti P, Xagoraris A, Romanski LM (1990) The lateral amygdaloid nucleus: Sensory interface of the amygdala in fear conditioning. J Neurosci 10, 1062-1069.
    • (1990) J Neurosci , vol.10 , pp. 1062-1069
    • Ledoux, J.E.1    Cicchetti, P.2    Xagoraris, A.3    Romanski, L.M.4
  • 53
    • 0026514823 scopus 로고
    • Modality-specific retrograde amnesia of fear
    • Kim JJ, Fanselow MS (1992) Modality-specific retrograde amnesia of fear. Science 256, 675-677.
    • (1992) Science , vol.256 , pp. 675-677
    • Kim, J.J.1    Fanselow, M.S.2
  • 54
    • 0026635574 scopus 로고
    • Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning
    • Phillips RG, LeDoux JE (1992) Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behav Neurosci 106, 274-285.
    • (1992) Behav Neurosci , vol.106 , pp. 274-285
    • Phillips, R.G.1    Ledoux, J.E.2
  • 55
    • 0029154914 scopus 로고
    • Differential contribution of dorsal and ventral medial prefrontal cortex to the acquisition and extinction of conditioned fear in rats
    • Morgan MA, LeDoux JE (1995) Differential contribution of dorsal and ventral medial prefrontal cortex to the acquisition and extinction of conditioned fear in rats. Behav Neurosci 109, 681-688.
    • (1995) Behav Neurosci , vol.109 , pp. 681-688
    • Morgan, M.A.1    Ledoux, J.E.2
  • 56
    • 0028933275 scopus 로고
    • Involvement of subcortical and cortical afferents to the lateral nucleus of the amygdala in fear conditioning measured with fear-potentiated startle in rats trained concurrently with auditory and visual conditioned stimuli
    • Campeau S, Davis M (1995) Involvement of subcortical and cortical afferents to the lateral nucleus of the amygdala in fear conditioning measured with fear-potentiated startle in rats trained concurrently with auditory and visual conditioned stimuli. J Neurosci 15, 2312-2327.
    • (1995) J Neurosci , vol.15 , pp. 2312-2327
    • Campeau, S.1    Davis, M.2
  • 57
    • 1842454162 scopus 로고    scopus 로고
    • Pavlovian fear conditioning regulates Thr286 autophosphorylation of Ca2+/calmodulin-dependent protein kinase II at lateral amygdala synapses
    • Rodrigues SM, Farb CR, Bauer EP, LeDoux JE, Schafe GE (2004) Pavlovian fear conditioning regulates Thr286 autophosphorylation of Ca2+/calmodulin- dependent protein kinase II at lateral amygdala synapses. J Neurosci 24, 3281-3288.
    • (2004) J Neurosci , vol.24 , pp. 3281-3288
    • Rodrigues, S.M.1    Farb, C.R.2    Bauer, E.P.3    Ledoux, J.E.4    Schafe, G.E.5
  • 58
    • 62649108345 scopus 로고    scopus 로고
    • Activation of CaMKII in single dendritic spines during longterm potentiation
    • Lee SJ, Escobedo-Lozoya Y, Szatmari EM, Yasuda R (2009) Activation of CaMKII in single dendritic spines during longterm potentiation. Nature 458, 299-304.
    • (2009) Nature , vol.458 , pp. 299-304
    • Lee, S.J.1    Escobedo-Lozoya, Y.2    Szatmari, E.M.3    Yasuda, R.4
  • 59
    • 15944411690 scopus 로고    scopus 로고
    • Postsynaptic receptor trafficking underlying a form of associative learning
    • Rumpel S, LeDoux J, Zador A, Malinow R (2005) Postsynaptic receptor trafficking underlying a form of associative learning. Science 308, 83-88.
    • (2005) Science , vol.308 , pp. 83-88
    • Rumpel, S.1    Ledoux, J.2    Zador, A.3    Malinow, R.4
  • 61
    • 77958534173 scopus 로고    scopus 로고
    • Endogenous GluR1-containing AMPA receptors translocate to asymmetric synapses in the lateral amygdala during the early phase of fear memory formation: An electron microscopic immunocytochemical study
    • Nedelescu H, Kelso CM, Lázaro-Muñoz G, Purpura M, Cain CK, Ledoux JE, Aoki C (2010) Endogenous GluR1-containing AMPA receptors translocate to asymmetric synapses in the lateral amygdala during the early phase of fear memory formation: An electron microscopic immunocytochemical study. J Comp Neurol 518, 4723-4739.
    • (2010) J Comp Neurol , vol.518 , pp. 4723-4739
    • Nedelescu, H.1    Kelso, C.M.2    Lázaro-Muñoz, G.3    Purpura, M.4    Cain, C.K.5    Ledoux, J.E.6    Aoki, C.7
  • 64
    • 58249118862 scopus 로고    scopus 로고
    • Transcription factors in long-term memory and synaptic plasticity
    • Alberini CM (2009) Transcription factors in long-term memory and synaptic plasticity. Physiol Rev 89, 121-145.
    • (2009) Physiol Rev , vol.89 , pp. 121-145
    • Alberini, C.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.