AID-expressing epithelium is protected from oncogenic transformation by an NKG2D surveillance pathway

EMBO Molecular Medicine

Volumn 7, Issue 10, 2015, Pages 1327-1336

  Pérez García, Arantxa ^a   Pérez Durán, Pablo ^a,d   Wossning, Thomas ^a,e   Sernandez, Isora V ^a,f   Mur, Sonia M ^a   Cañamero, Marta ^b   Real, Francisco X ^c   Ramiro, Almudena R ^a  

^a CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^b ROCHE DIAGNOSTICS GMBH   (Germany)

^c Structural Biology and Biocomputing Programme   (Spain)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e TUMOR BIOLOGY CENTER   (Germany)

^f Otsuka Pharmaceuticals   (Spain)

Author keywords

Activation induced deaminase; Cancer; Epithelium; NKG2D; Pancreas

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; NATURAL KILLER CELL RECEPTOR NKG2D; AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); CYTIDINE DEAMINASE; KLRK1 PROTEIN, MOUSE; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY K;

ADENOCARCINOMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARCINOGENESIS; CD8+ T LYMPHOCYTE; COLON; CONTROLLED STUDY; CYTOTOXICITY; DEXTRAN SODIUM SULFATE-INDUCED COLITIS; DOUBLE STRANDED DNA BREAK; EPITHELIUM CELL; GENE MUTATION; GENOTOXICITY; HETEROLOGOUS EXPRESSION; IMMUNOSURVEILLANCE; MALIGNANT TRANSFORMATION; MOUSE; MOUSE MODEL; NONHUMAN; PANCREAS; PRIORITY JOURNAL; ANIMAL; BIOSYNTHESIS; CELL DEATH; CELL TRANSFORMATION; CYTOTOXICITY TEST; EPITHELIUM; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL DEATH; CELL TRANSFORMATION, NEOPLASTIC; COLON; CYTIDINE DEAMINASE; CYTOTOXICITY TESTS, IMMUNOLOGIC; EPITHELIUM; MICE; MICE, TRANSGENIC; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; PANCREAS;

EID: 84942817994     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201505348     Document Type: Article

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