메뉴 건너뛰기




Volumn 63, Issue 38, 2015, Pages 8460-8471

Gynura procumbens Reverses Acute and Chronic Ethanol-Induced Liver Steatosis through MAPK/SREBP-1c-Dependent and -Independent Pathways

Author keywords

alcoholic liver disease; chlorogenic acid; Gynura procumbens; MAPK; SREBP 1c; steatosis

Indexed keywords

AMINO ACIDS;

EID: 84942626384     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/acs.jafc.5b03504     Document Type: Article
Times cited : (39)

References (43)
  • 1
    • 84926420371 scopus 로고    scopus 로고
    • Alcoholic liver disease: Mechanisms of injury and targeted treatment
    • Louvet, A.; Mathurin, P. Alcoholic liver disease: mechanisms of injury and targeted treatment Nat. Rev. Gastroenterol. Hepatol. 2015, 12, 231-42 10.1038/nrgastro.2015.35
    • (2015) Nat. Rev. Gastroenterol. Hepatol. , vol.12 , pp. 231-242
    • Louvet, A.1    Mathurin, P.2
  • 2
    • 84894216816 scopus 로고    scopus 로고
    • Silymarin and S-adenosyl-L-methionine (SAMe): Two promising pharmacological agents in case of chronic alcoholic hepathopathy. A review and a point of view
    • Testino, G.; Leone, S.; Ansaldi, F.; Borro, P. Silymarin and S-adenosyl-L-methionine (SAMe): two promising pharmacological agents in case of chronic alcoholic hepathopathy. A review and a point of view Minerva Gastroenterol. Dietol. 2013, 59, 341-56
    • (2013) Minerva Gastroenterol. Dietol. , vol.59 , pp. 341-356
    • Testino, G.1    Leone, S.2    Ansaldi, F.3    Borro, P.4
  • 3
    • 84907290726 scopus 로고    scopus 로고
    • Prevalence and risk factors of fatty liver disease in young and middle-aged population: One center study in Southwestern China
    • Xiao, S. J.; Fu, G. J.; Lv, Y. L.; Zhong, X. N.; Wang, R. H. Prevalence and risk factors of fatty liver disease in young and middle-aged population: one center study in Southwestern China J. Gastroenterol. Hepatol. 2014, 29, 358-64 10.1111/jgh.12334
    • (2014) J. Gastroenterol. Hepatol. , vol.29 , pp. 358-364
    • Xiao, S.J.1    Fu, G.J.2    Lv, Y.L.3    Zhong, X.N.4    Wang, R.H.5
  • 5
    • 84924565791 scopus 로고    scopus 로고
    • Protective effect of panax notoginseng saponins on acute ethanol-induced liver injury is associated with ameliorating hepatic lipid accumulation and reducing ethanol-mediated oxidative stress
    • Ding, R. B.; Tian, K.; Cao, Y. W.; Bao, J. L.; Wang, M.; He, C.; Hu, Y.; Su, H.; Wan, J. B. Protective effect of panax notoginseng saponins on acute ethanol-induced liver injury is associated with ameliorating hepatic lipid accumulation and reducing ethanol-mediated oxidative stress J. Agric. Food Chem. 2015, 63, 2413-22 10.1021/jf502990n
    • (2015) J. Agric. Food Chem. , vol.63 , pp. 2413-2422
    • Ding, R.B.1    Tian, K.2    Cao, Y.W.3    Bao, J.L.4    Wang, M.5    He, C.6    Hu, Y.7    Su, H.8    Wan, J.B.9
  • 7
    • 84875912175 scopus 로고    scopus 로고
    • Antiproliferative effect of gynura procumbens (lour.) Merr. Leaves etanolic extract on 7,12-dimethylbenz(a)antracene induced male rat liver
    • Nisa, F.; Hermawan, A.; Murwanti, R.; Meiyanto, E. Antiproliferative effect of gynura procumbens (lour.) Merr. Leaves etanolic extract on 7,12-dimethylbenz(a)antracene induced male rat liver Adv. Pharm. Bull. 2012, 2, 99-106 10.5681/apb.2012.014
    • (2012) Adv. Pharm. Bull. , vol.2 , pp. 99-106
    • Nisa, F.1    Hermawan, A.2    Murwanti, R.3    Meiyanto, E.4
  • 9
    • 77951935453 scopus 로고    scopus 로고
    • Anti-ulcerogenic activity of Gynura procumbens leaf extract against experimentally-induced gastric lesions in rats
    • Mahmood, A. A.; Mariod, A. A.; Al-Bayaty, F.; Abdel-Wahab, S. I. Anti-ulcerogenic activity of Gynura procumbens leaf extract against experimentally-induced gastric lesions in rats J. Med. Plant Res. 2010, 4, 685-91 10.5897/JMPR10.018
    • (2010) J. Med. Plant Res. , vol.4 , pp. 685-691
    • Mahmood, A.A.1    Mariod, A.A.2    Al-Bayaty, F.3    Abdel-Wahab, S.I.4
  • 10
    • 77953116832 scopus 로고    scopus 로고
    • Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis
    • Kim, C. W.; Moon, Y. A.; Park, S. W.; Cheng, D.; Kwon, H. J.; Horton, J. D. Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis Proc. Natl. Acad. Sci. U. S. A. 2010, 107, 9626-31 10.1073/pnas.1001292107
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 9626-9631
    • Kim, C.W.1    Moon, Y.A.2    Park, S.W.3    Cheng, D.4    Kwon, H.J.5    Horton, J.D.6
  • 11
    • 0034804783 scopus 로고    scopus 로고
    • Sterol regulatory element-binding proteins (SREBPs): Transcriptional regulators of lipid synthetic genes
    • Shimano, H. Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes Prog. Lipid Res. 2001, 40, 439-52 10.1016/S0163-7827(01)00010-8
    • (2001) Prog. Lipid Res. , vol.40 , pp. 439-452
    • Shimano, H.1
  • 12
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton, J. D.; Goldstein, J. L.; Brown, M. S. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver J. Clin. Invest. 2002, 109, 1125-31 10.1172/JCI0215593
    • (2002) J. Clin. Invest. , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 14
    • 33746354908 scopus 로고    scopus 로고
    • Alcohol and indinavir adversely affect protein synthesis and phosphorylation of MAPK and mTOR signaling pathways in C2C12 myocytes
    • Hong-Brown, L. Q.; Brown, C. R.; Huber, D. S.; Lang, C. H. Alcohol and indinavir adversely affect protein synthesis and phosphorylation of MAPK and mTOR signaling pathways in C2C12 myocytes Alcohol.: Clin. Exp. Res. 2006, 30, 1297-307 10.1111/j.1530-0277.2006.00157.x
    • (2006) Alcohol.: Clin. Exp. Res. , vol.30 , pp. 1297-1307
    • Hong-Brown, L.Q.1    Brown, C.R.2    Huber, D.S.3    Lang, C.H.4
  • 16
    • 33749253713 scopus 로고    scopus 로고
    • Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding model
    • Ji, C.; Chan, C.; Kaplowitz, N. Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding model J. Hepatol. 2006, 45, 717-24 10.1016/j.jhep.2006.05.009
    • (2006) J. Hepatol. , vol.45 , pp. 717-724
    • Ji, C.1    Chan, C.2    Kaplowitz, N.3
  • 17
    • 0029868268 scopus 로고    scopus 로고
    • Development and characterization of a binge drinking model in mice for evaluation of the immunological effects of ethanol
    • Carson, E. J.; Pruett, S. B. Development and characterization of a binge drinking model in mice for evaluation of the immunological effects of ethanol Alcohol.: Clin. Exp. Res. 1996, 20, 132-8 10.1111/j.1530-0277.1996.tb01055.x
    • (1996) Alcohol.: Clin. Exp. Res. , vol.20 , pp. 132-138
    • Carson, E.J.1    Pruett, S.B.2
  • 18
    • 84866383925 scopus 로고    scopus 로고
    • Acute alcohol-induced liver injury
    • Massey, V. L.; Arteel, G. E. Acute alcohol-induced liver injury Front. Physiol. 2012, 3, 193 10.3389/fphys.2012.00193
    • (2012) Front. Physiol. , vol.3 , pp. 193
    • Massey, V.L.1    Arteel, G.E.2
  • 19
    • 62749162644 scopus 로고    scopus 로고
    • Cinnamon extract protects against acute alcohol-induced liver steatosis in mice
    • Kanuri, G.; Weber, S.; Volynets, V.; Spruss, A.; Bischoff, S. C.; Bergheim, I. Cinnamon extract protects against acute alcohol-induced liver steatosis in mice J. Nutr. 2009, 139, 482-7 10.3945/jn.108.100495
    • (2009) J. Nutr. , vol.139 , pp. 482-487
    • Kanuri, G.1    Weber, S.2    Volynets, V.3    Spruss, A.4    Bischoff, S.C.5    Bergheim, I.6
  • 20
    • 0024326007 scopus 로고
    • Experimental methods of ethanol administration
    • Lieber, C. S.; DeCarli, L. M.; Sorrell, M. F. Experimental methods of ethanol administration Hepatology 1989, 10, 501-10 10.1002/hep.1840100417
    • (1989) Hepatology , vol.10 , pp. 501-510
    • Lieber, C.S.1    DeCarli, L.M.2    Sorrell, M.F.3
  • 21
    • 33644764092 scopus 로고    scopus 로고
    • Silymarin protects against acute ethanol-induced hepatotoxicity in mice
    • Song, Z.; Deaciuc, I.; Song, M.; Lee, D. Y.; Liu, Y.; Ji, X.; McClain, C. Silymarin protects against acute ethanol-induced hepatotoxicity in mice Alcohol.: Clin. Exp. Res. 2006, 30, 407-13 10.1111/j.1530-0277.2006.00063.x
    • (2006) Alcohol.: Clin. Exp. Res. , vol.30 , pp. 407-413
    • Song, Z.1    Deaciuc, I.2    Song, M.3    Lee, D.Y.4    Liu, Y.5    Ji, X.6    McClain, C.7
  • 22
    • 84861824396 scopus 로고    scopus 로고
    • Effect of Silymarin on Lipid and Alcohol Metabolism in Mice Following Long-Term Alcohol Consumption
    • Chou, C. H.; Chen, Y. C.; Hsu, M. C.; Tsai, W. L.; Chang, C. Y.; Chiu, C. H. Effect Of Silymarin on Lipid And Alcohol Metabolism In Mice Following Long-Term Alcohol Consumption J. Food Biochem. 2012, 36, 369-377 10.1111/j.1745-4514.2011.00543.x
    • (2012) J. Food Biochem. , vol.36 , pp. 369-377
    • Chou, C.H.1    Chen, Y.C.2    Hsu, M.C.3    Tsai, W.L.4    Chang, C.Y.5    Chiu, C.H.6
  • 23
    • 0037097027 scopus 로고    scopus 로고
    • Optimization of solid-phase microextraction conditions for gas chromatographic determination of ethanol and other volatile compounds in blood
    • Zuba, D.; Parczewski, A.; Reichenbacher, M. Optimization of solid-phase microextraction conditions for gas chromatographic determination of ethanol and other volatile compounds in blood J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 2002, 773, 75-82 10.1016/S1570-0232(02)00143-5
    • (2002) J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. , vol.773 , pp. 75-82
    • Zuba, D.1    Parczewski, A.2    Reichenbacher, M.3
  • 25
    • 84863060640 scopus 로고    scopus 로고
    • Dragon's blood inhibits chronic inflammatory and neuropathic pain responses by blocking the synthesis and release of substance P in rats
    • Li, Y. S.; Wang, J. X.; Jia, M. M.; Liu, M.; Li, X. J.; Tang, H. B. Dragon's blood inhibits chronic inflammatory and neuropathic pain responses by blocking the synthesis and release of substance P in rats J. Pharmacol. Sci. 2012, 118, 43-54 10.1254/jphs.11160FP
    • (2012) J. Pharmacol. Sci. , vol.118 , pp. 43-54
    • Li, Y.S.1    Wang, J.X.2    Jia, M.M.3    Liu, M.4    Li, X.J.5    Tang, H.B.6
  • 27
    • 84870299926 scopus 로고    scopus 로고
    • Herbal medicines for the prevention of alcoholic liver disease: A review
    • Ding, R. B.; Tian, K.; Huang, L. L.; He, C. W.; Jiang, Y.; Wang, Y. T.; Wan, J. B. Herbal medicines for the prevention of alcoholic liver disease: a review J. Ethnopharmacol. 2012, 144, 457-65 10.1016/j.jep.2012.09.044
    • (2012) J. Ethnopharmacol. , vol.144 , pp. 457-465
    • Ding, R.B.1    Tian, K.2    Huang, L.L.3    He, C.W.4    Jiang, Y.5    Wang, Y.T.6    Wan, J.B.7
  • 28
    • 0037047284 scopus 로고    scopus 로고
    • Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP)
    • You, M.; Fischer, M.; Deeg, M. A.; Crabb, D. W. Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP) J. Biol. Chem. 2002, 277, 29342-7 10.1074/jbc.M202411200
    • (2002) J. Biol. Chem. , vol.277 , pp. 29342-29347
    • You, M.1    Fischer, M.2    Deeg, M.A.3    Crabb, D.W.4
  • 29
    • 84930166799 scopus 로고    scopus 로고
    • Zeaxanthin dipalmitate therapeutically improves hepatic functions in an alcoholic fatty liver disease model through modulating MAPK pathway
    • Xiao, J.; Wang, J.; Xing, F.; Han, T.; Jiao, R.; Liong, E. C.; Fung, M. L.; So, K. F.; Tipoe, G. L. Zeaxanthin dipalmitate therapeutically improves hepatic functions in an alcoholic fatty liver disease model through modulating MAPK pathway PLoS One 2014, 9, e95214 10.1371/journal.pone.0095214
    • (2014) PLoS One , vol.9 , pp. e95214
    • Xiao, J.1    Wang, J.2    Xing, F.3    Han, T.4    Jiao, R.5    Liong, E.C.6    Fung, M.L.7    So, K.F.8    Tipoe, G.L.9
  • 30
    • 12744267804 scopus 로고    scopus 로고
    • Molecular mechanisms of alcoholic fatty liver: Role of sterol regulatory element-binding proteins
    • You, M.; Crabb, D. W. Molecular mechanisms of alcoholic fatty liver: role of sterol regulatory element-binding proteins Alcohol 2004, 34, 39-43 10.1016/j.alcohol.2004.07.004
    • (2004) Alcohol , vol.34 , pp. 39-43
    • You, M.1    Crabb, D.W.2
  • 31
    • 20844451123 scopus 로고    scopus 로고
    • AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
    • Kahn, B. B.; Alquier, T.; Carling, D.; Hardie, D. G. AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism Cell Metab. 2005, 1, 15-25 10.1016/j.cmet.2004.12.003
    • (2005) Cell Metab. , vol.1 , pp. 15-25
    • Kahn, B.B.1    Alquier, T.2    Carling, D.3    Hardie, D.G.4
  • 32
    • 84892440312 scopus 로고    scopus 로고
    • Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early-stage ethanol-mediated steatosis
    • Shearn, C. T.; Smathers, R. L.; Jiang, H.; Orlicky, D. J.; Maclean, K. N.; Petersen, D. R. Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early-stage ethanol-mediated steatosis J. Nutr. Biochem. 2013, 24, 1436-45 10.1016/j.jnutbio.2012.12.002
    • (2013) J. Nutr. Biochem. , vol.24 , pp. 1436-1445
    • Shearn, C.T.1    Smathers, R.L.2    Jiang, H.3    Orlicky, D.J.4    Maclean, K.N.5    Petersen, D.R.6
  • 34
    • 77249094005 scopus 로고    scopus 로고
    • Involvement of adiponectin-SIRT1-AMPK signaling in the protective action of rosiglitazone against alcoholic fatty liver in mice
    • Shen, Z.; Liang, X.; Rogers, C. Q.; Rideout, D.; You, M. Involvement of adiponectin-SIRT1-AMPK signaling in the protective action of rosiglitazone against alcoholic fatty liver in mice Am. J. Physiol. Gastrointest. Liver Physiol. 2010, 298, G364-74 10.1152/ajpgi.00456.2009
    • (2010) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.298 , pp. G364-G374
    • Shen, Z.1    Liang, X.2    Rogers, C.Q.3    Rideout, D.4    You, M.5
  • 35
    • 38949104356 scopus 로고    scopus 로고
    • Ethanol consumption impairs regulation of fatty acid metabolism by decreasing the activity of AMP-activated protein kinase in rat liver
    • Garcia-Villafranca, J.; Guillen, A.; Castro, J. Ethanol consumption impairs regulation of fatty acid metabolism by decreasing the activity of AMP-activated protein kinase in rat liver Biochimie 2008, 90, 460-6 10.1016/j.biochi.2007.09.019
    • (2008) Biochimie , vol.90 , pp. 460-466
    • Garcia-Villafranca, J.1    Guillen, A.2    Castro, J.3
  • 36
    • 84901724383 scopus 로고    scopus 로고
    • Identification of 5′ AMP-activated kinase as a target of reactive aldehydes during chronic ingestion of high concentrations of ethanol
    • Shearn, C. T.; Backos, D. S.; Orlicky, D. J.; Smathers-McCullough, R. L.; Petersen, D. R. Identification of 5′ AMP-activated kinase as a target of reactive aldehydes during chronic ingestion of high concentrations of ethanol J. Biol. Chem. 2014, 289, 15449-62 10.1074/jbc.M113.543942
    • (2014) J. Biol. Chem. , vol.289 , pp. 15449-15462
    • Shearn, C.T.1    Backos, D.S.2    Orlicky, D.J.3    Smathers-McCullough, R.L.4    Petersen, D.R.5
  • 37
    • 84884225440 scopus 로고    scopus 로고
    • Roles of Chlorogenic Acid on regulating glucose and lipids metabolism: A review
    • Meng, S.; Cao, J.; Feng, Q.; Peng, J.; Hu, Y. Roles of Chlorogenic Acid on regulating glucose and lipids metabolism: a review Evid. Based Complement. Alternat. Med. 2013, 2013, 801457 10.1155/2013/801457
    • (2013) Evid. Based Complement. Alternat. Med. , vol.2013 , pp. 801457
    • Meng, S.1    Cao, J.2    Feng, Q.3    Peng, J.4    Hu, Y.5
  • 38
    • 84923247234 scopus 로고    scopus 로고
    • Correction to Supplementation of a high-fat diet with chlorogenic acid is associated with insulin resistance and hepatic lipid accumulation in mice
    • Mubarak, A.; Hodgson, J. M.; Considine, M. J.; Croft, K. D.; Matthews, V. B. Correction to Supplementation of a high-fat diet with chlorogenic acid is associated with insulin resistance and hepatic lipid accumulation in mice J. Agric. Food Chem. 2015, 63, 1882 10.1021/acs.jafc.5b00621
    • (2015) J. Agric. Food Chem. , vol.63 , pp. 1882
    • Mubarak, A.1    Hodgson, J.M.2    Considine, M.J.3    Croft, K.D.4    Matthews, V.B.5
  • 39
    • 84942664148 scopus 로고    scopus 로고
    • The chemopreventive activity of chlorogenic acid is mediated by inhibiting AP-1-MAPKs pathway and inducing phase II detoxifying enzyme through stimulating Nrf2 signaling
    • Feng, R. T. The chemopreventive activity of chlorogenic acid is mediated by inhibiting AP-1-MAPKs pathway and inducing phase II detoxifying enzyme through stimulating Nrf2 signaling Cancer Epidem. Biomar. 2004, 13, 1880s
    • (2004) Cancer Epidem. Biomar. , vol.13 , pp. 1880s
    • Feng, R.T.1
  • 40
    • 84885771953 scopus 로고    scopus 로고
    • Chlorogenic acid, a dietary polyphenol, protects acetaminophen-induced liver injury and its mechanism
    • Ji, L.; Jiang, P.; Lu, B.; Sheng, Y.; Wang, X.; Wang, Z. Chlorogenic acid, a dietary polyphenol, protects acetaminophen-induced liver injury and its mechanism J. Nutr. Biochem. 2013, 24, 1911-9 10.1016/j.jnutbio.2013.05.007
    • (2013) J. Nutr. Biochem. , vol.24 , pp. 1911-1919
    • Ji, L.1    Jiang, P.2    Lu, B.3    Sheng, Y.4    Wang, X.5    Wang, Z.6
  • 43
    • 67649968443 scopus 로고    scopus 로고
    • Oxidative stress and alcoholic liver disease
    • Wu, D.; Cederbaum, A. I. Oxidative stress and alcoholic liver disease Semin. Liver Dis. 2009, 29, 141-54 10.1055/s-0029-1214370
    • (2009) Semin. Liver Dis. , vol.29 , pp. 141-154
    • Wu, D.1    Cederbaum, A.I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.