메뉴 건너뛰기




Volumn 90, Issue 3, 2008, Pages 460-466

Ethanol consumption impairs regulation of fatty acid metabolism by decreasing the activity of AMP-activated protein kinase in rat liver

Author keywords

5 Aminoimidazole 4 carboxamide ribonucleoside; AMP activated protein kinase; Ethanol; Fatty acid metabolism; Fatty liver

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ALCOHOL; CARNITINE PALMITOYLTRANSFERASE; FATTY ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; TRIACYLGLYCEROL;

EID: 38949104356     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2007.09.019     Document Type: Article
Times cited : (107)

References (42)
  • 1
    • 0028134772 scopus 로고
    • The biochemistry of alcohol-induced fatty liver
    • Day C.P., and Yeaman S.J. The biochemistry of alcohol-induced fatty liver. Biochim. Biophys. Acta 1215 (1994) 33-48
    • (1994) Biochim. Biophys. Acta , vol.1215 , pp. 33-48
    • Day, C.P.1    Yeaman, S.J.2
  • 3
    • 0034890078 scopus 로고    scopus 로고
    • Fatty liver vulnerability to endotoxin-induced damage despite NF-κB induction and inhibited caspase 3 activation
    • Yang S., Lin H., and Diehl A.M. Fatty liver vulnerability to endotoxin-induced damage despite NF-κB induction and inhibited caspase 3 activation. Am. J. Physiol. Gastrointest. Liver Physiol. 281 (2001) G382-G392
    • (2001) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.281
    • Yang, S.1    Lin, H.2    Diehl, A.M.3
  • 4
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediators of hepatic steatosis and liver injury
    • Browning J.D., and Horton J.D. Molecular mediators of hepatic steatosis and liver injury. J. Clin. Invest. 114 (2004) 147-152
    • (2004) J. Clin. Invest. , vol.114 , pp. 147-152
    • Browning, J.D.1    Horton, J.D.2
  • 5
    • 0022853738 scopus 로고
    • The effect of ethanol on the β-oxidation of fatty acids, Alcohol
    • Grunnet N., and Kondrup J. The effect of ethanol on the β-oxidation of fatty acids, Alcohol. Clin. Exp. Res. 10 Suppl. (1986) 64S-68S
    • (1986) Clin. Exp. Res. , vol.10 , Issue.SUPPL
    • Grunnet, N.1    Kondrup, J.2
  • 6
    • 0028350768 scopus 로고
    • Alcohol and the liver: 1994 update
    • Lieber C.S. Alcohol and the liver: 1994 update. Gastroenterology 106 (1994) 1085-1105
    • (1994) Gastroenterology , vol.106 , pp. 1085-1105
    • Lieber, C.S.1
  • 7
    • 0019796717 scopus 로고
    • Attenuation of the ethanol-induced hepatic redox change after chronic alcohol consumption in baboons: metabolic consequences in vivo and in vitro
    • Salaspuro M.P., Shaw S., Jayatilleke E., Ross W.A., and Lieber C.S. Attenuation of the ethanol-induced hepatic redox change after chronic alcohol consumption in baboons: metabolic consequences in vivo and in vitro. Hepatology 1 (1981) 33-38
    • (1981) Hepatology , vol.1 , pp. 33-38
    • Salaspuro, M.P.1    Shaw, S.2    Jayatilleke, E.3    Ross, W.A.4    Lieber, C.S.5
  • 8
    • 0021285210 scopus 로고
    • Hepatic triacylglycerol synthesizing activity during progression of alcoholic liver injury in the baboon
    • Savolainen M.J., Baraona E., Pikkarainen P., and Lieber C.S. Hepatic triacylglycerol synthesizing activity during progression of alcoholic liver injury in the baboon. J. Lipid Res. 25 (1984) 813-820
    • (1984) J. Lipid Res. , vol.25 , pp. 813-820
    • Savolainen, M.J.1    Baraona, E.2    Pikkarainen, P.3    Lieber, C.S.4
  • 9
    • 0035793237 scopus 로고    scopus 로고
    • Chronic ingestion of ethanol stimulates lipogenic response in rat hepatocytes
    • Carrasco M.P., Marco C., and Segovia J.L. Chronic ingestion of ethanol stimulates lipogenic response in rat hepatocytes. Life Sci. 68 (2001) 1295-1304
    • (2001) Life Sci. , vol.68 , pp. 1295-1304
    • Carrasco, M.P.1    Marco, C.2    Segovia, J.L.3
  • 10
    • 11144298683 scopus 로고    scopus 로고
    • Desensitization of cyclic GMP-mediated regulation of fatty acid metabolism in hepatocytes from ethanol-fed rats
    • García-Villafranca J., Guillén A., and Castro J. Desensitization of cyclic GMP-mediated regulation of fatty acid metabolism in hepatocytes from ethanol-fed rats. Int. J. Biochem. Cell Biol. 37 (2005) 655-664
    • (2005) Int. J. Biochem. Cell Biol. , vol.37 , pp. 655-664
    • García-Villafranca, J.1    Guillén, A.2    Castro, J.3
  • 11
    • 0023601680 scopus 로고
    • Ethanol feeding to rats reversibly decreases hepatic carnitine palmitoyltransferase activity and increases enzyme sensitivity to malonyl-CoA
    • Guzmán M., Castro J., and Maquedano A. Ethanol feeding to rats reversibly decreases hepatic carnitine palmitoyltransferase activity and increases enzyme sensitivity to malonyl-CoA. Biochem. Biophys. Res. Commun. 149 (1987) 443-448
    • (1987) Biochem. Biophys. Res. Commun. , vol.149 , pp. 443-448
    • Guzmán, M.1    Castro, J.2    Maquedano, A.3
  • 12
    • 0025309965 scopus 로고
    • Alterations in the regulatory properties of hepatic fatty acid oxidation and carnitine palmitoyltransferase I activity after ethanol feeding and withdrawal
    • Guzmán M., and Castro J. Alterations in the regulatory properties of hepatic fatty acid oxidation and carnitine palmitoyltransferase I activity after ethanol feeding and withdrawal. Alcohol. Clin. Exp. Res. 14 (1990) 472-477
    • (1990) Alcohol. Clin. Exp. Res. , vol.14 , pp. 472-477
    • Guzmán, M.1    Castro, J.2
  • 13
    • 0000243752 scopus 로고
    • The effect of ethanol on fatty acid metabolism; stimulation of hepatic fatty acid synthesis in vitro
    • Lieber C.S., and Schmid R. The effect of ethanol on fatty acid metabolism; stimulation of hepatic fatty acid synthesis in vitro. J. Clin. Invest. 40 (1961) 394-399
    • (1961) J. Clin. Invest. , vol.40 , pp. 394-399
    • Lieber, C.S.1    Schmid, R.2
  • 14
    • 0032716189 scopus 로고    scopus 로고
    • De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption
    • Siler S.Q., Neese R.A., and Hellerstein M.K. De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption. Am. J. Clin. Nutr. 70 (1999) 928-936
    • (1999) Am. J. Clin. Nutr. , vol.70 , pp. 928-936
    • Siler, S.Q.1    Neese, R.A.2    Hellerstein, M.K.3
  • 16
    • 0037047284 scopus 로고    scopus 로고
    • Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP)
    • You M., Fischer M., Deeg M.A., and Crabb D.W. Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP). J. Biol. Chem. 277 (2002) 29342-29347
    • (2002) J. Biol. Chem. , vol.277 , pp. 29342-29347
    • You, M.1    Fischer, M.2    Deeg, M.A.3    Crabb, D.W.4
  • 17
    • 0034870748 scopus 로고    scopus 로고
    • Energy sensing and signaling by AMP-activated protein kinase in skeletal muscle
    • Winder W.W. Energy sensing and signaling by AMP-activated protein kinase in skeletal muscle. J. Appl. Physiol. 91 (2001) 1017-1028
    • (2001) J. Appl. Physiol. , vol.91 , pp. 1017-1028
    • Winder, W.W.1
  • 18
    • 0347318052 scopus 로고    scopus 로고
    • The AMP-activated protein kinase cascade - a unifying system for energy control
    • Carling D. The AMP-activated protein kinase cascade - a unifying system for energy control. Trends Biochem. Sci. 29 (2004) 18-24
    • (2004) Trends Biochem. Sci. , vol.29 , pp. 18-24
    • Carling, D.1
  • 19
    • 14544271907 scopus 로고    scopus 로고
    • AMP-activated protein kinase: balancing the scales
    • Carling D. AMP-activated protein kinase: balancing the scales. Biochimie 87 (2005) 87-91
    • (2005) Biochimie , vol.87 , pp. 87-91
    • Carling, D.1
  • 20
    • 0026604926 scopus 로고
    • Regulation of fatty acid and cholesterol metabolism by the AMP-activated protein kinase
    • Hardie D.G. Regulation of fatty acid and cholesterol metabolism by the AMP-activated protein kinase. Biochim. Biophys. Acta 1123 (1992) 231-238
    • (1992) Biochim. Biophys. Acta , vol.1123 , pp. 231-238
    • Hardie, D.G.1
  • 21
    • 0031717105 scopus 로고    scopus 로고
    • The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?
    • Hardie D.G., Carling D., and Carlson M. The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?. Annu. Rev. Biochem. 67 (1998) 821-855
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 821-855
    • Hardie, D.G.1    Carling, D.2    Carlson, M.3
  • 22
    • 0030795278 scopus 로고    scopus 로고
    • Regulation of mammalian acetyl-coenzyme A carboxylase
    • Kim K.H. Regulation of mammalian acetyl-coenzyme A carboxylase. Annu. Rev. Nutr. 17 (1997) 77-99
    • (1997) Annu. Rev. Nutr. , vol.17 , pp. 77-99
    • Kim, K.H.1
  • 23
    • 0031043030 scopus 로고    scopus 로고
    • The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis
    • McGarry J.D., and Brown N.F. The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis. Eur. J. Biochem. 244 (1997) 1-14
    • (1997) Eur. J. Biochem. , vol.244 , pp. 1-14
    • McGarry, J.D.1    Brown, N.F.2
  • 24
    • 0142181286 scopus 로고    scopus 로고
    • Malonyl-CoA and AMP-activated protein kinase: an expanding partnership
    • Saha A.K., and Ruderman N.B. Malonyl-CoA and AMP-activated protein kinase: an expanding partnership. Mol. Cell. Biochem. 253 (2003) 65-70
    • (2003) Mol. Cell. Biochem. , vol.253 , pp. 65-70
    • Saha, A.K.1    Ruderman, N.B.2
  • 25
    • 85047689953 scopus 로고
    • 5-Aminoimidazole-4-carboxamide ribonucleoside: a specific method for activating AMP-activated protein kinase in intact cells?
    • Corton J.M., Guillespie J.G., Hawley S.A., and Hardie D.G. 5-Aminoimidazole-4-carboxamide ribonucleoside: a specific method for activating AMP-activated protein kinase in intact cells?. Eur. J. Biochem. 229 (1995) 558-565
    • (1995) Eur. J. Biochem. , vol.229 , pp. 558-565
    • Corton, J.M.1    Guillespie, J.G.2    Hawley, S.A.3    Hardie, D.G.4
  • 26
    • 0024409956 scopus 로고
    • Liquid diet technique of ethanol administration: 1989 update
    • Lieber C.S., and DeCarli L.M. Liquid diet technique of ethanol administration: 1989 update. Alcohol Alcohol. 24 (1989) 197-211
    • (1989) Alcohol Alcohol. , vol.24 , pp. 197-211
    • Lieber, C.S.1    DeCarli, L.M.2
  • 27
    • 0024786438 scopus 로고
    • Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities
    • Carling D., Clarke P.R., Zammit V.A., and Hardie D.G. Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities. Eur. J. Biochem. 186 (1989) 129-136
    • (1989) Eur. J. Biochem. , vol.186 , pp. 129-136
    • Carling, D.1    Clarke, P.R.2    Zammit, V.A.3    Hardie, D.G.4
  • 28
    • 0024839973 scopus 로고
    • Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay
    • Davies S.P., Carling D., and Hardie D.G. Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay. Eur. J. Biochem. 186 (1989) 123-128
    • (1989) Eur. J. Biochem. , vol.186 , pp. 123-128
    • Davies, S.P.1    Carling, D.2    Hardie, D.G.3
  • 29
    • 0018613319 scopus 로고
    • Opposite effects of insulin and glucagon in acute hormonal control of hepatic lipogenesis
    • Beynen A.C., Vaartjes W.J., and Geelen M.J.H. Opposite effects of insulin and glucagon in acute hormonal control of hepatic lipogenesis. Diabetes 28 (1979) 828-835
    • (1979) Diabetes , vol.28 , pp. 828-835
    • Beynen, A.C.1    Vaartjes, W.J.2    Geelen, M.J.H.3
  • 30
    • 0023259178 scopus 로고
    • Measurement of acetyl-CoA carboxylase activity in isolated hepatocytes
    • Bijleveld C., and Geelen M.J.H. Measurement of acetyl-CoA carboxylase activity in isolated hepatocytes. Biochim. Biophys. Acta 918 (1987) 274-283
    • (1987) Biochim. Biophys. Acta , vol.918 , pp. 274-283
    • Bijleveld, C.1    Geelen, M.J.H.2
  • 31
    • 0024451784 scopus 로고
    • Zonation of fatty acid metabolism in rat liver
    • Guzmán M., and Castro J. Zonation of fatty acid metabolism in rat liver. Biochem. J. 264 (1989) 107-113
    • (1989) Biochem. J. , vol.264 , pp. 107-113
    • Guzmán, M.1    Castro, J.2
  • 32
    • 0026707744 scopus 로고
    • Activity of carnitine palmitoyltransferase in mitochondrial outer membranes and peroxisomes in digitonin-permeabilized hepatocytes
    • Guzmán M., and Geelen M.J.H. Activity of carnitine palmitoyltransferase in mitochondrial outer membranes and peroxisomes in digitonin-permeabilized hepatocytes. Biochem. J. 287 (1992) 487-492
    • (1992) Biochem. J. , vol.287 , pp. 487-492
    • Guzmán, M.1    Geelen, M.J.H.2
  • 33
    • 33845261493 scopus 로고
    • A rapid method of the total lipid extraction and purification
    • Bligh E., and Dyer W.J. A rapid method of the total lipid extraction and purification. Can. J. Biochem. Physiol. 37 (1959) 911-917
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.1    Dyer, W.J.2
  • 35
    • 0033559856 scopus 로고    scopus 로고
    • AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target
    • Muoio D.M., Seefeld K., Witters L.A., and Coleman R.A. AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target. Biochem. J. 338 (1999) 783-791
    • (1999) Biochem. J. , vol.338 , pp. 783-791
    • Muoio, D.M.1    Seefeld, K.2    Witters, L.A.3    Coleman, R.A.4
  • 36
    • 0027162774 scopus 로고
    • Acetate-induced changes of adenine nucleotide levels in rat liver
    • Zydowo M.M., Smolenski R.T., and Swierczynski J. Acetate-induced changes of adenine nucleotide levels in rat liver. Metabolism 42 (1993) 644-648
    • (1993) Metabolism , vol.42 , pp. 644-648
    • Zydowo, M.M.1    Smolenski, R.T.2    Swierczynski, J.3
  • 37
    • 0029123160 scopus 로고
    • Effect of chronic ethanol consumption on the energy state and structural stability of periportal and perivenous hepatocytes
    • Ivester P., Lide M.J., and Cunningham C.C. Effect of chronic ethanol consumption on the energy state and structural stability of periportal and perivenous hepatocytes. Arch. Biochem. Biophys. 322 (1995) 14-21
    • (1995) Arch. Biochem. Biophys. , vol.322 , pp. 14-21
    • Ivester, P.1    Lide, M.J.2    Cunningham, C.C.3
  • 38
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver disease in mice
    • Xu A., Wang Y., Keshaw H., Xu L.Y., Lam K.S.L., and Cooper G.J.S. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver disease in mice. J. Clin. Invest. 112 (2003) 91-100
    • (2003) J. Clin. Invest. , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3    Xu, L.Y.4    Lam, K.S.L.5    Cooper, G.J.S.6
  • 41
    • 9644290860 scopus 로고    scopus 로고
    • The role of AMP-activated protein kinase in the action of ethanol in the liver
    • You M., Matsumoto M., Pacold C.M., Cho W.K., and Crabb D.W. The role of AMP-activated protein kinase in the action of ethanol in the liver. Gastroenterology 127 (2004) 1798-1808
    • (2004) Gastroenterology , vol.127 , pp. 1798-1808
    • You, M.1    Matsumoto, M.2    Pacold, C.M.3    Cho, W.K.4    Crabb, D.W.5
  • 42
    • 10044271037 scopus 로고    scopus 로고
    • SREBP transcription factors: master regulators of lipid homeostasis
    • Eberlé D., Hegarty B., Bossard P., Ferré P., and Foufelle F. SREBP transcription factors: master regulators of lipid homeostasis. Biochimie 86 (2004) 839-848
    • (2004) Biochimie , vol.86 , pp. 839-848
    • Eberlé, D.1    Hegarty, B.2    Bossard, P.3    Ferré, P.4    Foufelle, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.