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Volumn 126, Issue 10, 2015, Pages 1224-1233

Autophagy is induced upon platelet activation and is essential for hemostasis and thrombosis

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; AUTOPHAGY PROTEIN 7; BIOLOGICAL MARKER; CELLUBREVIN; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FERRIC CHLORIDE; LC3II; MEMBRANE PROTEIN; MESSENGER RNA; PROTEINASE; PROTEINASE INHIBITOR; SYNAPTOBREVIN 2; THROMBIN; THROMBOCYTE FACTOR 4; UNCLASSIFIED DRUG; VAMP 8 PROTEIN;

EID: 84942519336     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-09-598722     Document Type: Article
Times cited : (116)

References (85)
  • 1
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature. 2008;451(7182):1069-1075.
    • (2008) Nature , vol.451 , Issue.7182 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 2
    • 33748433101 scopus 로고    scopus 로고
    • Lysosomal chat maintains the balance
    • Massey AC, Kaushik S, Cuervo AM. Lysosomal chat maintains the balance. Autophagy. 2006;2(4):325-327.
    • (2006) Autophagy , vol.2 , Issue.4 , pp. 325-327
    • Massey, A.C.1    Kaushik, S.2    Cuervo, A.M.3
  • 3
    • 1642329712 scopus 로고    scopus 로고
    • Determination of four sequential stages during microautophagy in vitro
    • Kunz JB, Schwarz H, Mayer A. Determination of four sequential stages during microautophagy in vitro. J Biol Chem. 2004;279(11):9987-9996.
    • (2004) J Biol Chem , vol.279 , Issue.11 , pp. 9987-9996
    • Kunz, J.B.1    Schwarz, H.2    Mayer, A.3
  • 4
    • 33846116102 scopus 로고    scopus 로고
    • The vacuolar transporter chaperone (VTC) complex is required for microautophagy
    • Uttenweiler A, Schwarz H, Neumann H, Mayer A. The vacuolar transporter chaperone (VTC) complex is required for microautophagy. Mol Biol Cell. 2007;18(1):166-175.
    • (2007) Mol Biol Cell , vol.18 , Issue.1 , pp. 166-175
    • Uttenweiler, A.1    Schwarz, H.2    Neumann, H.3    Mayer, A.4
  • 5
    • 34248139628 scopus 로고    scopus 로고
    • Molecular machinery of autophagosome formation in yeast, Saccharomyces cerevisiae
    • Suzuki K, Ohsumi Y. Molecular machinery of autophagosome formation in yeast, Saccharomyces cerevisiae. FEBS Lett. 2007;581(11):2156-2161.
    • (2007) FEBS Lett , vol.581 , Issue.11 , pp. 2156-2161
    • Suzuki, K.1    Ohsumi, Y.2
  • 6
    • 84870880174 scopus 로고    scopus 로고
    • The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes
    • Itakura E, Kishi-Itakura C, Mizushima N. The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes. Cell. 2012;151(6):1256-1269.
    • (2012) Cell , vol.151 , Issue.6 , pp. 1256-1269
    • Itakura, E.1    Kishi-Itakura, C.2    Mizushima, N.3
  • 7
    • 67649467294 scopus 로고    scopus 로고
    • Dynamics and diversity in autophagy mechanisms: Lessons from yeast
    • Nakatogawa H, Suzuki K, Kamada Y, Ohsumi Y. Dynamics and diversity in autophagy mechanisms: lessons from yeast. Nat Rev Mol Cell Biol. 2009;10(7):458-467.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , Issue.7 , pp. 458-467
    • Nakatogawa, H.1    Suzuki, K.2    Kamada, Y.3    Ohsumi, Y.4
  • 8
    • 84888380983 scopus 로고    scopus 로고
    • The autophagosome: Origins unknown, biogenesis complex
    • Lamb CA, Yoshimori T, Tooze SA. The autophagosome: origins unknown, biogenesis complex. Nat Rev Mol Cell Biol. 2013;14(12):759-774.
    • (2013) Nat Rev Mol Cell Biol , vol.14 , Issue.12 , pp. 759-774
    • Lamb, C.A.1    Yoshimori, T.2    Tooze, S.A.3
  • 10
    • 79953127788 scopus 로고    scopus 로고
    • Autophagosome formation in mammalian cells
    • Burman C, Ktistakis NT. Autophagosome formation in mammalian cells. Semin Immunopathol. 2010;32(4):397-413.
    • (2010) Semin Immunopathol , vol.32 , Issue.4 , pp. 397-413
    • Burman, C.1    Ktistakis, N.T.2
  • 11
    • 65249155441 scopus 로고    scopus 로고
    • An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation
    • Chang YY, Neufeld TP. An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation. Mol Biol Cell. 2009;20(7):2004-2014.
    • (2009) Mol Biol Cell , vol.20 , Issue.7 , pp. 2004-2014
    • Chang, Y.Y.1    Neufeld, T.P.2
  • 12
    • 65249176304 scopus 로고    scopus 로고
    • ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
    • Jung CH, Jun CB, Ro SH, et al. ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol Biol Cell. 2009;20(7):1992-2003.
    • (2009) Mol Biol Cell , vol.20 , Issue.7 , pp. 1992-2003
    • Jung, C.H.1    Jun, C.B.2    Ro, S.H.3
  • 13
    • 66449083078 scopus 로고    scopus 로고
    • ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy
    • Ganley IG, Lam H, Wang J, Ding X, Chen S, Jiang X. ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. J Biol Chem. 2009;284(18):12297-12305.
    • (2009) J Biol Chem , vol.284 , Issue.18 , pp. 12297-12305
    • Ganley, I.G.1    Lam, H.2    Wang, J.3    Ding, X.4    Chen, S.5    Jiang, X.6
  • 14
    • 65249119430 scopus 로고    scopus 로고
    • Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy
    • Hosokawa N, Hara T, Kaizuka T, et al. Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. Mol Biol Cell. 2009;20(7):1981-1991.
    • (2009) Mol Biol Cell , vol.20 , Issue.7 , pp. 1981-1991
    • Hosokawa, N.1    Hara, T.2    Kaizuka, T.3
  • 15
    • 84875365804 scopus 로고    scopus 로고
    • Autophagosomes form at ER-mitochondria contact sites
    • Hamasaki M, Furuta N, Matsuda A, et al. Autophagosomes form at ER-mitochondria contact sites. Nature. 2013;495(7441):389-393.
    • (2013) Nature , vol.495 , Issue.7441 , pp. 389-393
    • Hamasaki, M.1    Furuta, N.2    Matsuda, A.3
  • 16
    • 59249089394 scopus 로고    scopus 로고
    • Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG
    • Itakura E, Kishi C, Inoue K, Mizushima N. Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol Biol Cell. 2008;19(12):5360-5372.
    • (2008) Mol Biol Cell , vol.19 , Issue.12 , pp. 5360-5372
    • Itakura, E.1    Kishi, C.2    Inoue, K.3    Mizushima, N.4
  • 17
    • 58049192897 scopus 로고    scopus 로고
    • Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase
    • Sun Q, Fan W, Chen K, Ding X, Chen S, Zhong Q. Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase. Proc Natl Acad Sci USA. 2008;105(49):19211-19216.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.49 , pp. 19211-19216
    • Sun, Q.1    Fan, W.2    Chen, K.3    Ding, X.4    Chen, S.5    Zhong, Q.6
  • 18
    • 64049113909 scopus 로고    scopus 로고
    • Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
    • Zhong Y, Wang QJ, Li X, et al. Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat Cell Biol. 2009;11(4):468-476.
    • (2009) Nat Cell Biol , vol.11 , Issue.4 , pp. 468-476
    • Zhong, Y.1    Wang, Q.J.2    Li, X.3
  • 19
    • 64049086758 scopus 로고    scopus 로고
    • Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
    • Matsunaga K, Saitoh T, Tabata K, et al. Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Nat Cell Biol. 2009;11(4):385-396.
    • (2009) Nat Cell Biol , vol.11 , Issue.4 , pp. 385-396
    • Matsunaga, K.1    Saitoh, T.2    Tabata, K.3
  • 20
    • 77955895424 scopus 로고    scopus 로고
    • Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L
    • Matsunaga K, Morita E, Saitoh T, et al. Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L. J Cell Biol. 2010;190(4):511-521.
    • (2010) J Cell Biol , vol.190 , Issue.4 , pp. 511-521
    • Matsunaga, K.1    Morita, E.2    Saitoh, T.3
  • 21
    • 77955884684 scopus 로고    scopus 로고
    • Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins
    • Itakura E, Mizushima N. Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins. Autophagy. 2010;6(6):764-776.
    • (2010) Autophagy , vol.6 , Issue.6 , pp. 764-776
    • Itakura, E.1    Mizushima, N.2
  • 22
    • 0032563798 scopus 로고    scopus 로고
    • A protein conjugation system essential for autophagy
    • Mizushima N, Noda T, Yoshimori T, et al. A protein conjugation system essential for autophagy. Nature. 1998;395(6700):395-398.
    • (1998) Nature , vol.395 , Issue.6700 , pp. 395-398
    • Mizushima, N.1    Noda, T.2    Yoshimori, T.3
  • 23
    • 0032545292 scopus 로고    scopus 로고
    • A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy
    • Mizushima N, Sugita H, Yoshimori T, Ohsumi Y. A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy. J Biol Chem. 1998;273(51):33889-33892.
    • (1998) J Biol Chem , vol.273 , Issue.51 , pp. 33889-33892
    • Mizushima, N.1    Sugita, H.2    Yoshimori, T.3    Ohsumi, Y.4
  • 24
    • 0033214582 scopus 로고    scopus 로고
    • Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast
    • Shintani T, Mizushima N, Ogawa Y, Matsuura A, Noda T, Ohsumi Y. Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast. EMBO J. 1999;18(19):5234-5241.
    • (1999) EMBO J , vol.18 , Issue.19 , pp. 5234-5241
    • Shintani, T.1    Mizushima, N.2    Ogawa, Y.3    Matsuura, A.4    Noda, T.5    Ohsumi, Y.6
  • 25
    • 0034707036 scopus 로고    scopus 로고
    • A ubiquitin-like system mediates protein lipidation
    • Ichimura Y, Kirisako T, Takao T, et al. A ubiquitin-like system mediates protein lipidation. Nature. 2000;408(6811):488-492.
    • (2000) Nature , vol.408 , Issue.6811 , pp. 488-492
    • Ichimura, Y.1    Kirisako, T.2    Takao, T.3
  • 26
    • 38049098543 scopus 로고    scopus 로고
    • The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy
    • Hanada T, Noda NN, Satomi Y, et al. The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy. J Biol Chem. 2007;282(52):37298-37302.
    • (2007) J Biol Chem , vol.282 , Issue.52 , pp. 37298-37302
    • Hanada, T.1    Noda, N.N.2    Satomi, Y.3
  • 27
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • Kabeya Y, Mizushima N, Ueno T, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J. 2000;19(21):5720-5728.
    • (2000) EMBO J , vol.19 , Issue.21 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3
  • 28
    • 84878615771 scopus 로고    scopus 로고
    • Autophagosomal Syntaxin17-dependent lysosomal degradation maintains neuronal function in Drosophila
    • Takáts S, Nagy P, Varga Á, et al. Autophagosomal Syntaxin17-dependent lysosomal degradation maintains neuronal function in Drosophila. J Cell Biol. 2013;201(4):531-539.
    • (2013) J Cell Biol , vol.201 , Issue.4 , pp. 531-539
    • Takáts, S.1    Nagy, P.2    Varga, Á.3
  • 29
    • 72049088519 scopus 로고    scopus 로고
    • TI-VAMP/VAMP7 and VAMP3/cellubrevin: Two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways
    • Fader CM, Sánchez DG, Mestre MB, Colombo MI. TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways. Biochim Biophys Acta. 2009;1793(12):1901-1916.
    • (2009) Biochim Biophys Acta , vol.1793 , Issue.12 , pp. 1901-1916
    • Fader, C.M.1    Sánchez, D.G.2    Mestre, M.B.3    Colombo, M.I.4
  • 30
    • 84928550400 scopus 로고    scopus 로고
    • ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes
    • Diao J, Liu R, Rong Y, et al. ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes. Nature. 2015;520(7548):563-566.
    • (2015) Nature , vol.520 , Issue.7548 , pp. 563-566
    • Diao, J.1    Liu, R.2    Rong, Y.3
  • 31
    • 84876570034 scopus 로고    scopus 로고
    • Deletion of autophagy-related 5 (Atg5) and Pik3c3 genes in the lens causes cataract independent of programmed organelle degradation
    • Morishita H, Eguchi S, Kimura H, et al. Deletion of autophagy-related 5 (Atg5) and Pik3c3 genes in the lens causes cataract independent of programmed organelle degradation. J Biol Chem. 2013;288(16):11436-11447.
    • (2013) J Biol Chem , vol.288 , Issue.16 , pp. 11436-11447
    • Morishita, H.1    Eguchi, S.2    Kimura, H.3
  • 32
    • 51649124519 scopus 로고    scopus 로고
    • Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
    • Kundu M, Lindsten T, Yang CY, et al. Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation. Blood. 2008;112(4):1493-1502.
    • (2008) Blood , vol.112 , Issue.4 , pp. 1493-1502
    • Kundu, M.1    Lindsten, T.2    Yang, C.Y.3
  • 33
    • 37649017266 scopus 로고    scopus 로고
    • NIX is required for programmed mitochondrial clearance during reticulocyte maturation
    • Schweers RL, Zhang J, Randall MS, et al. NIX is required for programmed mitochondrial clearance during reticulocyte maturation. Proc Natl Acad Sci USA. 2007;104(49):19500-19505.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.49 , pp. 19500-19505
    • Schweers, R.L.1    Zhang, J.2    Randall, M.S.3
  • 34
    • 47049100413 scopus 로고    scopus 로고
    • Essential role for Nix in autophagic maturation of erythroid cells
    • Sandoval H, Thiagarajan P, Dasgupta SK, et al. Essential role for Nix in autophagic maturation of erythroid cells. Nature. 2008;454(7201):232-235.
    • (2008) Nature , vol.454 , Issue.7201 , pp. 232-235
    • Sandoval, H.1    Thiagarajan, P.2    Dasgupta, S.K.3
  • 35
    • 67650230871 scopus 로고    scopus 로고
    • Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation
    • Zhang J, Randall MS, Loyd MR, et al. Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation. Blood. 2009;114(1):157-164.
    • (2009) Blood , vol.114 , Issue.1 , pp. 157-164
    • Zhang, J.1    Randall, M.S.2    Loyd, M.R.3
  • 36
    • 70349687405 scopus 로고    scopus 로고
    • Discovery of Atg5/Atg7-independent alternative macroautophagy
    • Nishida Y, Arakawa S, Fujitani K, et al. Discovery of Atg5/Atg7-independent alternative macroautophagy. Nature. 2009;461(7264):654-658.
    • (2009) Nature , vol.461 , Issue.7264 , pp. 654-658
    • Nishida, Y.1    Arakawa, S.2    Fujitani, K.3
  • 37
    • 28444455308 scopus 로고    scopus 로고
    • Organelle degradation during the lens and erythroid differentiation is independent of autophagy
    • Matsui M, Yamamoto A, Kuma A, Ohsumi Y, Mizushima N. Organelle degradation during the lens and erythroid differentiation is independent of autophagy. Biochem Biophys Res Commun. 2006;339(2):485-489.
    • (2006) Biochem Biophys Res Commun , vol.339 , Issue.2 , pp. 485-489
    • Matsui, M.1    Yamamoto, A.2    Kuma, A.3    Ohsumi, Y.4    Mizushima, N.5
  • 38
    • 76249127368 scopus 로고    scopus 로고
    • Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo
    • Mortensen M, Ferguson DJ, Edelmann M, et al. Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo. Proc Natl Acad Sci USA. 2010;107(2):832-837.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.2 , pp. 832-837
    • Mortensen, M.1    Ferguson, D.J.2    Edelmann, M.3
  • 39
    • 84925135644 scopus 로고    scopus 로고
    • Autophagy regulates the cell cycle of murine HSPCs in a nutrient-dependent manner
    • Cao Y, Zhang A, Cai J, et al. Autophagy regulates the cell cycle of murine HSPCs in a nutrient-dependent manner. Exp Hematol. 2015;43(3):229-242.
    • (2015) Exp Hematol , vol.43 , Issue.3 , pp. 229-242
    • Cao, Y.1    Zhang, A.2    Cai, J.3
  • 40
    • 84898625169 scopus 로고    scopus 로고
    • Dissection of autophagy in human platelets
    • Feng W, Chang C, Luo D, et al. Dissection of autophagy in human platelets. Autophagy. 2014;10(4):642-651.
    • (2014) Autophagy , vol.10 , Issue.4 , pp. 642-651
    • Feng, W.1    Chang, C.2    Luo, D.3
  • 41
    • 1542283812 scopus 로고    scopus 로고
    • In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
    • Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell. 2004;15(3):1101-1111.
    • (2004) Mol Biol Cell , vol.15 , Issue.3 , pp. 1101-1111
    • Mizushima, N.1    Yamamoto, A.2    Matsui, M.3    Yoshimori, T.4    Ohsumi, Y.5
  • 42
    • 38049066964 scopus 로고    scopus 로고
    • Chromosomal mapping of the GFP-LC3 transgene in GFP-LC3 mice
    • Kuma A, Mizushima N. Chromosomal mapping of the GFP-LC3 transgene in GFP-LC3 mice. Autophagy. 2008;4(1):61-62.
    • (2008) Autophagy , vol.4 , Issue.1 , pp. 61-62
    • Kuma, A.1    Mizushima, N.2
  • 43
    • 49949098271 scopus 로고    scopus 로고
    • BAC-mediated transgenic expression of fluorescent autophagic protein Beclin 1 reveals a role for Beclin 1 in lymphocyte development
    • Arsov I, Li X, Matthews G, et al. BAC-mediated transgenic expression of fluorescent autophagic protein Beclin 1 reveals a role for Beclin 1 in lymphocyte development. Cell Death Differ. 2008;15(9):1385-1395.
    • (2008) Cell Death Differ , vol.15 , Issue.9 , pp. 1385-1395
    • Arsov, I.1    Li, X.2    Matthews, G.3
  • 44
    • 0035651255 scopus 로고    scopus 로고
    • BAC to the future: The use of bac transgenic mice for neuroscience research
    • Heintz N. BAC to the future: the use of bac transgenic mice for neuroscience research. Nat Rev Neurosci. 2001;2(12):861-870.
    • (2001) Nat Rev Neurosci , vol.2 , Issue.12 , pp. 861-870
    • Heintz, N.1
  • 45
    • 33846045579 scopus 로고    scopus 로고
    • Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reaction
    • Ren Q, Barber HK, Crawford GL, et al. Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reaction. Mol Biol Cell. 2007;18(1):24-33.
    • (2007) Mol Biol Cell , vol.18 , Issue.1 , pp. 24-33
    • Ren, Q.1    Barber, H.K.2    Crawford, G.L.3
  • 46
    • 33846911975 scopus 로고    scopus 로고
    • Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo
    • Tiedt R, Schomber T, Hao-Shen H, Skoda RC. Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo. Blood. 2007;109(4):1503-1506.
    • (2007) Blood , vol.109 , Issue.4 , pp. 1503-1506
    • Tiedt, R.1    Schomber, T.2    Hao-Shen, H.3    Skoda, R.C.4
  • 47
    • 68149178554 scopus 로고    scopus 로고
    • Linking genetically defined neurons to behavior through a broadly applicable silencing allele
    • Kim JC, Cook MN, Carey MR, Shen C, Regehr WG, Dymecki SM. Linking genetically defined neurons to behavior through a broadly applicable silencing allele. Neuron. 2009;63(3):305-315.
    • (2009) Neuron , vol.63 , Issue.3 , pp. 305-315
    • Kim, J.C.1    Cook, M.N.2    Carey, M.R.3    Shen, C.4    Regehr, W.G.5    Dymecki, S.M.6
  • 48
    • 21044455137 scopus 로고    scopus 로고
    • Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
    • Komatsu M, Waguri S, Ueno T, et al. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol. 2005;169(3):425-434.
    • (2005) J Cell Biol , vol.169 , Issue.3 , pp. 425-434
    • Komatsu, M.1    Waguri, S.2    Ueno, T.3
  • 49
    • 33645736307 scopus 로고    scopus 로고
    • Arf6 plays an early role in platelet activation by collagen and convulxin
    • Choi W, Karim ZA, Whiteheart SW. Arf6 plays an early role in platelet activation by collagen and convulxin. Blood. 2006;107(8):3145-3152.
    • (2006) Blood , vol.107 , Issue.8 , pp. 3145-3152
    • Choi, W.1    Karim, Z.A.2    Whiteheart, S.W.3
  • 50
    • 77956519683 scopus 로고    scopus 로고
    • Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis
    • Ren Q, Wimmer C, Chicka MC, et al. Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis. Blood. 2010;116(6):869-877.
    • (2010) Blood , vol.116 , Issue.6 , pp. 869-877
    • Ren, Q.1    Wimmer, C.2    Chicka, M.C.3
  • 51
    • 0034283702 scopus 로고    scopus 로고
    • Molecular mechanisms of platelet exocytosis: Role of SNAP-23 and syntaxin 2 and 4 in lysosome release
    • Chen D, Lemons PP, Schraw T, Whiteheart SW. Molecular mechanisms of platelet exocytosis: role of SNAP-23 and syntaxin 2 and 4 in lysosome release. Blood. 2000;96(5):1782-1788.
    • (2000) Blood , vol.96 , Issue.5 , pp. 1782-1788
    • Chen, D.1    Lemons, P.P.2    Schraw, T.3    Whiteheart, S.W.4
  • 52
    • 0034719338 scopus 로고    scopus 로고
    • Molecular mechanisms of platelet exocytosis: Requirements for alpha-granule release
    • Lemons PP, Chen D, Whiteheart SW. Molecular mechanisms of platelet exocytosis: requirements for alpha-granule release. Biochem Biophys Res Commun. 2000;267(3):875-880.
    • (2000) Biochem Biophys Res Commun , vol.267 , Issue.3 , pp. 875-880
    • Lemons, P.P.1    Chen, D.2    Whiteheart, S.W.3
  • 53
    • 18544383153 scopus 로고    scopus 로고
    • The development of a quantitative enzyme-linked immunosorbent assay to detect human platelet factor 4
    • Schraw T, Whiteheart S. The development of a quantitative enzyme-linked immunosorbent assay to detect human platelet factor 4. Transfusion. 2005;45(5):717-724.
    • (2005) Transfusion , vol.45 , Issue.5 , pp. 717-724
    • Schraw, T.1    Whiteheart, S.2
  • 54
    • 0034142239 scopus 로고    scopus 로고
    • Molecular mechanisms of platelet exocytosis: Role of SNAP-23 and syntaxin 2 in dense core granule release
    • Chen D, Bernstein AM, Lemons PP, Whiteheart SW. Molecular mechanisms of platelet exocytosis: role of SNAP-23 and syntaxin 2 in dense core granule release. Blood. 2000;95(3):921-929.
    • (2000) Blood , vol.95 , Issue.3 , pp. 921-929
    • Chen, D.1    Bernstein, A.M.2    Lemons, P.P.3    Whiteheart, S.W.4
  • 55
    • 0042178376 scopus 로고    scopus 로고
    • Granule stores from cellubrevin/VAMP-3 null mouse platelets exhibit normal stimulus-induced release
    • Schraw TD, Rutledge TW, Crawford GL, et al. Granule stores from cellubrevin/VAMP-3 null mouse platelets exhibit normal stimulus-induced release. Blood. 2003;102(5):1716-1722.
    • (2003) Blood , vol.102 , Issue.5 , pp. 1716-1722
    • Schraw, T.D.1    Rutledge, T.W.2    Crawford, G.L.3
  • 56
    • 80053377119 scopus 로고    scopus 로고
    • Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation
    • Zhang G, Xiang B, Dong A, et al. Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation. Blood. 2011;118(13):3670-3679.
    • (2011) Blood , vol.118 , Issue.13 , pp. 3670-3679
    • Zhang, G.1    Xiang, B.2    Dong, A.3
  • 57
    • 79961071855 scopus 로고    scopus 로고
    • Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes
    • Rowley JW, Oler AJ, Tolley ND, et al. Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes. Blood. 2011;118(14):e101-e111.
    • (2011) Blood , vol.118 , Issue.14 , pp. e101-e111
    • Rowley, J.W.1    Oler, A.J.2    Tolley, N.D.3
  • 58
    • 33645741132 scopus 로고    scopus 로고
    • Analysis of SAGE data in human platelets: Features of the transcriptome in an anucleate cell
    • Dittrich M, Birschmann I, Pfrang J, et al. Analysis of SAGE data in human platelets: features of the transcriptome in an anucleate cell. Thromb Haemost. 2006;95(4):643-651.
    • (2006) Thromb Haemost , vol.95 , Issue.4 , pp. 643-651
    • Dittrich, M.1    Birschmann, I.2    Pfrang, J.3
  • 59
    • 11144320641 scopus 로고    scopus 로고
    • Open source system for analyzing, validating, and storing protein identification data
    • Craig R, Cortens JP, Beavis RC. Open source system for analyzing, validating, and storing protein identification data. J Proteome Res. 2004;3(6):1234-1242.
    • (2004) J Proteome Res , vol.3 , Issue.6 , pp. 1234-1242
    • Craig, R.1    Cortens, J.P.2    Beavis, R.C.3
  • 60
    • 67651056213 scopus 로고    scopus 로고
    • Platelet membrane proteomics: A novel repository for functional research
    • Lewandrowski U, Wortelkamp S, Lohrig K, et al. Platelet membrane proteomics: a novel repository for functional research. Blood. 2009;114(1):e10-e19.
    • (2009) Blood , vol.114 , Issue.1 , pp. e10-e19
    • Lewandrowski, U.1    Wortelkamp, S.2    Lohrig, K.3
  • 61
    • 84867754221 scopus 로고    scopus 로고
    • The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways
    • Burkhart JM, Vaudel M, Gambaryan S, et al. The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways. Blood. 2012;120(15):e73-e82.
    • (2012) Blood , vol.120 , Issue.15 , pp. e73-e82
    • Burkhart, J.M.1    Vaudel, M.2    Gambaryan, S.3
  • 62
    • 84925811153 scopus 로고    scopus 로고
    • Copy number analysis of the murine platelet proteome spanning the complete abundance range
    • Zeiler M, Moser M, Mann M. Copy number analysis of the murine platelet proteome spanning the complete abundance range. Mol Cell Proteomics. 2014;13(12):3435-3445.
    • (2014) Mol Cell Proteomics , vol.13 , Issue.12 , pp. 3435-3445
    • Zeiler, M.1    Moser, M.2    Mann, M.3
  • 63
    • 84907007266 scopus 로고    scopus 로고
    • Proteasome function is required for platelet production
    • Shi DS, Smith MC, Campbell RA, et al. Proteasome function is required for platelet production. J Clin Invest. 2014;124(9):3757-3766.
    • (2014) J Clin Invest , vol.124 , Issue.9 , pp. 3757-3766
    • Shi, D.S.1    Smith, M.C.2    Campbell, R.A.3
  • 67
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell. 2010;140(3):313-326.
    • (2010) Cell , vol.140 , Issue.3 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 68
    • 27944504351 scopus 로고    scopus 로고
    • p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
    • Bjørkøy G, Lamark T, Brech A, et al. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol. 2005;171(4):603-614.
    • (2005) J Cell Biol , vol.171 , Issue.4 , pp. 603-614
    • Bjørkøy, G.1    Lamark, T.2    Brech, A.3
  • 69
    • 33748154216 scopus 로고    scopus 로고
    • Induction of autophagy in axonal dystrophy and degeneration
    • Wang QJ, Ding Y, Kohtz DS, et al. Induction of autophagy in axonal dystrophy and degeneration. J Neurosci. 2006;26(31):8057-8068.
    • (2006) J Neurosci , vol.26 , Issue.31 , pp. 8057-8068
    • Wang, Q.J.1    Ding, Y.2    Kohtz, D.S.3
  • 70
    • 84907215529 scopus 로고    scopus 로고
    • Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels
    • Zhong Y, Morris DH, Jin L, et al. Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels. J Biol Chem. 2014;29(38):26021-26037.
    • (2014) J Biol Chem , vol.29 , Issue.38 , pp. 26021-26037
    • Zhong, Y.1    Morris, D.H.2    Jin, L.3
  • 71
    • 84887489438 scopus 로고    scopus 로고
    • Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor
    • Torisu T, Torisu K, Lee IH, et al. Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor. Nat Med. 2013;19(10):1281-1287.
    • (2013) Nat Med , vol.19 , Issue.10 , pp. 1281-1287
    • Torisu, T.1    Torisu, K.2    Lee, I.H.3
  • 73
    • 33847404337 scopus 로고    scopus 로고
    • Autophagy gene-dependent clearance of apoptotic cells during embryonic development
    • Qu X, Zou Z, Sun Q, et al. Autophagy gene-dependent clearance of apoptotic cells during embryonic development. Cell. 2007;128(5):931-946.
    • (2007) Cell , vol.128 , Issue.5 , pp. 931-946
    • Qu, X.1    Zou, Z.2    Sun, Q.3
  • 74
    • 0026688548 scopus 로고
    • Platelet procoagulant activity and microvesicle formation. Its putative role in hemostasis and thrombosis
    • Zwaal RF, Comfurius P, Bevers EM. Platelet procoagulant activity and microvesicle formation. Its putative role in hemostasis and thrombosis. Biochim Biophys Acta. 1992;1180(1):1-8.
    • (1992) Biochim Biophys Acta , vol.1180 , Issue.1 , pp. 1-8
    • Zwaal, R.F.1    Comfurius, P.2    Bevers, E.M.3
  • 76
    • 1542317617 scopus 로고    scopus 로고
    • Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2
    • Woulfe D, Jiang H, Morgans A, Monks R, Birnbaum M, Brass LF. Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2. J Clin Invest. 2004;113(3):441-450.
    • (2004) J Clin Invest , vol.113 , Issue.3 , pp. 441-450
    • Woulfe, D.1    Jiang, H.2    Morgans, A.3    Monks, R.4    Birnbaum, M.5    Brass, L.F.6
  • 77
    • 61749097572 scopus 로고    scopus 로고
    • PKCalpha regulates platelet granule secretion and thrombus formation in mice
    • Konopatskaya O, Gilio K, Harper MT, et al. PKCalpha regulates platelet granule secretion and thrombus formation in mice. J Clin Invest. 2009;119(2):399-407.
    • (2009) J Clin Invest , vol.119 , Issue.2 , pp. 399-407
    • Konopatskaya, O.1    Gilio, K.2    Harper, M.T.3
  • 78
    • 77953282996 scopus 로고    scopus 로고
    • Platelet JNK1 is involved in secretion and thrombus formation
    • Adam F, Kauskot A, Nurden P, et al. Platelet JNK1 is involved in secretion and thrombus formation. Blood. 2010;115(20):4083-4092.
    • (2010) Blood , vol.115 , Issue.20 , pp. 4083-4092
    • Adam, F.1    Kauskot, A.2    Nurden, P.3
  • 79
    • 84873029127 scopus 로고    scopus 로고
    • Impaired thrombin-induced platelet activation and thrombus formation in mice lacking the Ca(2+)-dependent tyrosine kinase Pyk2
    • Canobbio I, Cipolla L, Consonni A, et al. Impaired thrombin-induced platelet activation and thrombus formation in mice lacking the Ca(2+)-dependent tyrosine kinase Pyk2. Blood. 2013;121(4):648-657.
    • (2013) Blood , vol.121 , Issue.4 , pp. 648-657
    • Canobbio, I.1    Cipolla, L.2    Consonni, A.3
  • 80
    • 84907486928 scopus 로고    scopus 로고
    • Platelet secretion and hemostasis require syntaxin-binding protein STXBP5
    • Ye S, Huang Y, Joshi S, et al. Platelet secretion and hemostasis require syntaxin-binding protein STXBP5. J Clin Invest. 2014;124(10):4517-4528.
    • (2014) J Clin Invest , vol.124 , Issue.10 , pp. 4517-4528
    • Ye, S.1    Huang, Y.2    Joshi, S.3
  • 81
  • 82
    • 0025915935 scopus 로고
    • Proteasome and its novel endogeneous activator in human platelets
    • Yukawa M, Sakon M, Kambayashi J, et al. Proteasome and its novel endogeneous activator in human platelets. Biochem Biophys Res Commun. 1991;178(1):256-262.
    • (1991) Biochem Biophys Res Commun , vol.178 , Issue.1 , pp. 256-262
    • Yukawa, M.1    Sakon, M.2    Kambayashi, J.3
  • 83
    • 0027482398 scopus 로고
    • Purification and characterization of endogenous protein activator of human platelet proteasome
    • Yukawa M, Sakon M, Kambayashi J, et al. Purification and characterization of endogenous protein activator of human platelet proteasome. J Biochem. 1993;114(3):317-323.
    • (1993) J Biochem , vol.114 , Issue.3 , pp. 317-323
    • Yukawa, M.1    Sakon, M.2    Kambayashi, J.3
  • 85
    • 84908167740 scopus 로고    scopus 로고
    • Platelet vacuoles in a dog with severe nonregenerative anemia: Evidence of platelet autophagy
    • Pieczarka EM, Yamaguchi M, Wellman ML, Judith Radin M. Platelet vacuoles in a dog with severe nonregenerative anemia: evidence of platelet autophagy. Vet Clin Pathol. 2014;43(3):326-329.
    • (2014) Vet Clin Pathol , vol.43 , Issue.3 , pp. 326-329
    • Pieczarka, E.M.1    Yamaguchi, M.2    Wellman, M.L.3    Judith Radin, M.4


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