메뉴 건너뛰기




Volumn 124, Issue 10, 2014, Pages 4517-4528

Platelet secretion and hemostasis require syntaxin-binding protein STXBP5

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; HETERODIMER; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; PADGEM PROTEIN; SECRETORY COMPONENT; SYNAPTOSOMAL ASSOCIATED PROTEIN 23; SYNTAXIN; SYNTAXIN 11; SYNTAXIN BINDING PROTEIN 5; UNCLASSIFIED DRUG; NERVE PROTEIN; SNARE PROTEIN; STXBP5 PROTEIN, HUMAN; SYNAPTOBREVIN; TOMOSYN PROTEIN, MOUSE;

EID: 84907486928     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI75572     Document Type: Article
Times cited : (50)

References (58)
  • 1
    • 75949128633 scopus 로고    scopus 로고
    • Antiplatelet therapies for the treatment of cardiovascular disease
    • Michelson AD. Antiplatelet therapies for the treatment of cardiovascular disease. Nat Rev Drug Discov. 2010;9(2):154-169.
    • (2010) Nat Rev Drug Discov. , vol.9 , Issue.2 , pp. 154-169
    • Michelson, A.D.1
  • 2
    • 79958117692 scopus 로고    scopus 로고
    • Antiplatelet agents in cardiovascular disease
    • Lopes RD. Antiplatelet agents in cardiovascular disease. J Thromb Thrombolysis. 2011;31(3):306-309.
    • (2011) J Thromb Thrombolysis. , vol.31 , Issue.3 , pp. 306-309
    • Lopes, R.D.1
  • 3
    • 1842708803 scopus 로고    scopus 로고
    • San Diego, California, USA: Elservier Science
    • Michelson AD. Platelets. San Diego, California, USA: Elservier Science; 2002.
    • (2002) Platelets
    • Michelson, A.D.1
  • 4
    • 70349254628 scopus 로고    scopus 로고
    • Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivo
    • Graham GJ, Ren Q, Dilks JR, Blair P, Whiteheart SW, Flaumenhaft R. Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivo. Blood. 2009;114(5):1083-1090.
    • (2009) Blood , vol.114 , Issue.5 , pp. 1083-1090
    • Graham, G.J.1    Ren, Q.2    Dilks, J.R.3    Blair, P.4    Whiteheart, S.W.5    Flaumenhaft, R.6
  • 5
    • 0032549708 scopus 로고    scopus 로고
    • SNAREpins: Minimal machinery for membrane fusion
    • Weber T, et al. SNAREpins: minimal machinery for membrane fusion. Cell. 1998;92(6):759-772.
    • (1998) Cell , vol.92 , Issue.6 , pp. 759-772
    • Weber, T.1
  • 6
    • 0034142239 scopus 로고    scopus 로고
    • Molecular mechanisms of platelet exocytosis: Role of SNAP-23 and syntaxin 2 in dense core granule release
    • Chen D, Bernstein AM, Lemons PP, Whiteheart SW. Molecular mechanisms of platelet exocytosis: role of SNAP-23 and syntaxin 2 in dense core granule release. Blood. 2000;95(3):921-929.
    • (2000) Blood , vol.95 , Issue.3 , pp. 921-929
    • Chen, D.1    Bernstein, A.M.2    Lemons, P.P.3    Whiteheart, S.W.4
  • 7
    • 0034283702 scopus 로고    scopus 로고
    • Molecular mechanisms of platelet exocytosis: Role of SNAP-23 and syntaxin 2 and 4 in lysosome release
    • Chen D, Lemons PP, Schraw T, Whiteheart SW. Molecular mechanisms of platelet exocytosis: role of SNAP-23 and syntaxin 2 and 4 in lysosome release. Blood. 2000;96(5):1782-1788.
    • (2000) Blood , vol.96 , Issue.5 , pp. 1782-1788
    • Chen, D.1    Lemons, P.P.2    Schraw, T.3    Whiteheart, S.W.4
  • 8
    • 34548814973 scopus 로고    scopus 로고
    • Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients
    • Bryceson YT, et al. Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients. Blood. 2007;110(6):1906-1915.
    • (2007) Blood , vol.110 , Issue.6 , pp. 1906-1915
    • Bryceson, Y.T.1
  • 9
    • 84866536865 scopus 로고    scopus 로고
    • Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion
    • Ye S, Karim ZA, Al Hawas R, Pessin JE, Filipovich AH, Whiteheart SW. Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion. Blood. 2012;120(12):2484-2492.
    • (2012) Blood , vol.120 , Issue.12 , pp. 2484-2492
    • Ye, S.1    Karim, Z.A.2    Al Hawas, R.3    Pessin, J.E.4    Filipovich, A.H.5    Whiteheart, S.W.6
  • 10
    • 58849092285 scopus 로고    scopus 로고
    • Membrane fusion: Grappling with SNARE and SM proteins
    • Sudhof TC, Rothman JE. Membrane fusion: grappling with SNARE and SM proteins. Science. 2009;323(5913):474-477.
    • (2009) Science , vol.323 , Issue.5913 , pp. 474-477
    • Sudhof, T.C.1    Rothman, J.E.2
  • 11
    • 1542409030 scopus 로고    scopus 로고
    • The specificity of SNARE-dependent fusion is encoded in the SNARE motif
    • Paumet F, Rahimian V, Rothman JE. The specificity of SNARE-dependent fusion is encoded in the SNARE motif. Proc Natl Acad Sci U S A. 2004;101(10):3376-3380.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.10 , pp. 3376-3380
    • Paumet, F.1    Rahimian, V.2    Rothman, J.E.3
  • 14
    • 79960890548 scopus 로고    scopus 로고
    • Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels
    • Antoni G, et al. Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels. BMC Med Genet. 2011;12:102.
    • (2011) BMC Med Genet. , vol.12 , pp. 102
    • Antoni, G.1
  • 15
    • 79955964538 scopus 로고    scopus 로고
    • Genetic determinants of plasma von Willebrand factor antigen levels: A target gene SNP and haplotype analysis of ARIC cohort
    • Campos M, et al. Genetic determinants of plasma von Willebrand factor antigen levels: a target gene SNP and haplotype analysis of ARIC cohort. Blood. 2011;117(19):5224-5230.
    • (2011) Blood , vol.117 , Issue.19 , pp. 5224-5230
    • Campos, M.1
  • 16
    • 79957977435 scopus 로고    scopus 로고
    • Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis
    • Smith NL, et al. Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis. Blood. 2011;117(22):6007-6011.
    • (2011) Blood , vol.117 , Issue.22 , pp. 6007-6011
    • Smith, N.L.1
  • 17
    • 77950217693 scopus 로고    scopus 로고
    • Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium
    • Smith NL, et al. Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation. 2010;121(12):1382-1392.
    • (2010) Circulation. , vol.121 , Issue.12 , pp. 1382-1392
    • Smith, N.L.1
  • 18
    • 84863636752 scopus 로고    scopus 로고
    • Effect of genetic variation in STXBP5 and STX2 on von Willebrand factor and bleeding phenotype in type 1 von Willebrand disease patients
    • Van Loon JE, Sanders YV, De Wee EM, Kruip MJ, De Maat MP, Leebeek FW. Effect of genetic variation in STXBP5 and STX2 on von Willebrand factor and bleeding phenotype in type 1 von Willebrand disease patients. PLoS One. 2012;7(7):e40624.
    • (2012) PLoS One. , vol.7 , Issue.7 , pp. e40624
    • Van Loon, J.E.1    Sanders, Y.V.2    De Wee, E.M.3    Kruip, M.J.4    De Maat, M.P.5    Leebeek, F.W.6
  • 19
    • 79952813198 scopus 로고    scopus 로고
    • Effect of genetic variations in syntaxin-binding protein-5 and syntaxin-2 on von Willebrand factor concentration and cardiovascular risk
    • Van Loon JE, et al. Effect of genetic variations in syntaxin-binding protein-5 and syntaxin-2 on von Willebrand factor concentration and cardiovascular risk. Circ Cardiovasc Genet. 2010;3(6):507-512.
    • (2010) Circ Cardiovasc Genet. , vol.3 , Issue.6 , pp. 507-512
    • Van Loon, J.E.1
  • 20
    • 84899653256 scopus 로고    scopus 로고
    • Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2
    • Huang J, et al. Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol. 2014;34(5):1093-1101.
    • (2014) Arterioscler Thromb Vasc Biol. , vol.34 , Issue.5 , pp. 1093-1101
    • Huang, J.1
  • 21
    • 17344376286 scopus 로고    scopus 로고
    • Tomosyn: A syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process
    • Fujita Y, et al. Tomosyn: a syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process. Neuron. 1998;20(5):905-915.
    • (1998) Neuron. , vol.20 , Issue.5 , pp. 905-915
    • Fujita, Y.1
  • 22
    • 0042818205 scopus 로고    scopus 로고
    • Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulinstimulated GLUT4 translocation
    • Widberg CH, Bryant NJ, Girotti M, Rea S, James DE. Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulinstimulated GLUT4 translocation. J Biol Chem. 2003;278(37):35093-35101.
    • (2003) J Biol Chem. , vol.278 , Issue.37 , pp. 35093-35101
    • Widberg, C.H.1    Bryant, N.J.2    Girotti, M.3    Rea, S.4    James, D.E.5
  • 23
    • 0037008753 scopus 로고    scopus 로고
    • Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assembly
    • Scales SJ, Hesser BA, Masuda ES, Scheller RH. Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assembly. J Biol Chem. 2002;277(31):28271-28279.
    • (2002) J Biol Chem. , vol.277 , Issue.31 , pp. 28271-28279
    • Scales, S.J.1    Hesser, B.A.2    Masuda, E.S.3    Scheller, R.H.4
  • 24
    • 65349152502 scopus 로고    scopus 로고
    • Friends and foes in synaptic transmission: The role of tomosyn in vesicle priming
    • Ashery U, Bielopolski N, Barak B, Yizhar O. Friends and foes in synaptic transmission: the role of tomosyn in vesicle priming. Trends Neurosci. 2009;32(5):275-282.
    • (2009) Trends Neurosci. , vol.32 , Issue.5 , pp. 275-282
    • Ashery, U.1    Bielopolski, N.2    Barak, B.3    Yizhar, O.4
  • 25
    • 0033549568 scopus 로고    scopus 로고
    • Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9
    • Lehman K, Rossi G, Adamo JE, Brennwald P. Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9. J Cell Biol. 1999;146(1):125-140.
    • (1999) J Cell Biol. , vol.146 , Issue.1 , pp. 125-140
    • Lehman, K.1    Rossi, G.2    Adamo, J.E.3    Brennwald, P.4
  • 26
    • 37249047613 scopus 로고    scopus 로고
    • Tomosyn negatively regulates both synaptic transmitter and neuropeptide release at the C. Elegans neuromuscular junction
    • Gracheva EO, Burdina AO, Touroutine D, Berthelot-Grosjean M, Parekh H, Richmond JE. Tomosyn negatively regulates both synaptic transmitter and neuropeptide release at the C. elegans neuromuscular junction. J Physiol. 2007;585(pt 3):705-709.
    • (2007) J Physiol. , vol.585 , pp. 705-709
    • Gracheva, E.O.1    Burdina, A.O.2    Touroutine, D.3    Berthelot-Grosjean, M.4    Parekh, H.5    Richmond, J.E.6
  • 27
    • 0028061614 scopus 로고
    • The Drosophila lethal (2) giant larvae tumor suppressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain
    • Strand D, et al. The Drosophila lethal (2) giant larvae tumor suppressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain. J Cell Biol. 1994;127(5):1361-1373.
    • (1994) J Cell Biol. , vol.127 , Issue.5 , pp. 1361-1373
    • Strand, D.1
  • 28
    • 0032576569 scopus 로고    scopus 로고
    • Tropomyosin-containing actin cables direct the Myo2p-dependent polarized delivery of secretory vesicles in budding yeast
    • Pruyne DW, Schott DH, Bretscher A. Tropomyosin-containing actin cables direct the Myo2p-dependent polarized delivery of secretory vesicles in budding yeast. J Cell Biol. 1998;143(7):1931-1945.
    • (1998) J Cell Biol. , vol.143 , Issue.7 , pp. 1931-1945
    • Pruyne, D.W.1    Schott, D.H.2    Bretscher, A.3
  • 29
    • 0033525719 scopus 로고    scopus 로고
    • Three splicing variants of tomosyn and identification of their syntaxin-binding region
    • Yokoyama S, Shirataki H, Sakisaka T, Takai Y. Three splicing variants of tomosyn and identification of their syntaxin-binding region. Biochem Biophys Res Commun. 1999;256(1):218-222.
    • (1999) Biochem Biophys Res Commun. , vol.256 , Issue.1 , pp. 218-222
    • Yokoyama, S.1    Shirataki, H.2    Sakisaka, T.3    Takai, Y.4
  • 30
    • 13244292391 scopus 로고    scopus 로고
    • Two distinct genes drive expression of seven tomosyn isoforms in the mammalian brain, sharing a conserved structure with a unique variable domain
    • Groffen AJ, Jacobsen L, Schut D, Verhage M. Two distinct genes drive expression of seven tomosyn isoforms in the mammalian brain, sharing a conserved structure with a unique variable domain. J Neurochem. 2005;92(3):554-568.
    • (2005) J Neurochem. , vol.92 , Issue.3 , pp. 554-568
    • Groffen, A.J.1    Jacobsen, L.2    Schut, D.3    Verhage, M.4
  • 31
    • 0042733066 scopus 로고    scopus 로고
    • The R-SNARE motif of tomosyn forms SNARE core complexes with syntaxin 1 and SNAP-25 and down-regulates exocytosis
    • Hatsuzawa K, Lang T, Fasshauer D, Bruns D, Jahn R. The R-SNARE motif of tomosyn forms SNARE core complexes with syntaxin 1 and SNAP-25 and down-regulates exocytosis. J Biol Chem. 2003;278(33):31159-31166.
    • (2003) J Biol Chem. , vol.278 , Issue.33 , pp. 31159-31166
    • Hatsuzawa, K.1    Lang, T.2    Fasshauer, D.3    Bruns, D.4    Jahn, R.5
  • 32
    • 55949121583 scopus 로고    scopus 로고
    • Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release
    • Sakisaka T, et al. Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release. J Cell Biol. 2008;183(2):323-337.
    • (2008) J Cell Biol. , vol.183 , Issue.2 , pp. 323-337
    • Sakisaka, T.1
  • 33
    • 34848928507 scopus 로고    scopus 로고
    • Multiple functional domains are involved in tomosyn regulation of exocytosis
    • Yizhar O, et al. Multiple functional domains are involved in tomosyn regulation of exocytosis. J Neurochem. 2007;103(2):604-616.
    • (2007) J Neurochem. , vol.103 , Issue.2 , pp. 604-616
    • Yizhar, O.1
  • 35
    • 33746853822 scopus 로고    scopus 로고
    • Tomosyn-1 is involved in a postdocking event required for pancreatic beta-cell exocytosis
    • Cheviet S, et al. Tomosyn-1 is involved in a postdocking event required for pancreatic beta-cell exocytosis. J Cell Sci. 2006;119(pt 14):2912-2920.
    • (2006) J Cell Sci. , vol.119 , pp. 2912-2920
    • Cheviet, S.1
  • 36
    • 84872306469 scopus 로고    scopus 로고
    • Novel copy number variants in children with autism and additional developmental anomalies
    • Davis LK, et al. Novel copy number variants in children with autism and additional developmental anomalies. J Neurodev Disord. 2009;1(4):292-301.
    • (2009) J Neurodev Disord. , vol.1 , Issue.4 , pp. 292-301
    • Davis, L.K.1
  • 37
    • 78650660345 scopus 로고    scopus 로고
    • Platelet secretion defect in patients with familial hemophagocytic lymphohistiocytosis type 5 (FHL-5)
    • Sandrock K, Nakamura L, Vraetz T, Beutel K, Ehl S, Zieger B. Platelet secretion defect in patients with familial hemophagocytic lymphohistiocytosis type 5 (FHL-5). Blood. 2010;116(26):6148-6150.
    • (2010) Blood , vol.116 , Issue.26 , pp. 6148-6150
    • Sandrock, K.1    Nakamura, L.2    Vraetz, T.3    Beutel, K.4    Ehl, S.5    Zieger, B.6
  • 38
    • 84873046084 scopus 로고    scopus 로고
    • Synaptotagmin-like protein 4 and Rab8 interact and increase dense granule release in platelets
    • Hampson A, O'Connor A, Smolenski A. Synaptotagmin-like protein 4 and Rab8 interact and increase dense granule release in platelets. J Thromb Haemost. 2013;11(1):161-168.
    • (2013) J Thromb Haemost. , vol.11 , Issue.1 , pp. 161-168
    • Hampson, A.1    O'Connor, A.2    Smolenski, A.3
  • 39
    • 1442354782 scopus 로고    scopus 로고
    • Tomosyn inhibits priming of large dense-core vesicles in a calciumdependent manner
    • Yizhar O, et al. Tomosyn inhibits priming of large dense-core vesicles in a calciumdependent manner. Proc Natl Acad Sci U S A. 2004;101(8):2578-2583.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.8 , pp. 2578-2583
    • Yizhar, O.1
  • 40
    • 33644783907 scopus 로고    scopus 로고
    • Tomosyn is expressed in betacells and negatively regulates insulin exocytosis
    • Zhang W, et al. Tomosyn is expressed in betacells and negatively regulates insulin exocytosis. Diabetes. 2006;55(3):574-581.
    • (2006) Diabetes. , vol.55 , Issue.3 , pp. 574-581
    • Zhang, W.1
  • 41
    • 84855877960 scopus 로고    scopus 로고
    • Systematic and quantitative comparison of digest efficiency and specificity reveals the impact of trypsin quality on MS-based proteomics
    • Burkhart JM, Schumbrutzki C, Wortelkamp S, Sickmann A, Zahedi RP. Systematic and quantitative comparison of digest efficiency and specificity reveals the impact of trypsin quality on MS-based proteomics. J Proteomics. 2012;75(4):1454-1462.
    • (2012) J Proteomics. , vol.75 , Issue.4 , pp. 1454-1462
    • Burkhart, J.M.1    Schumbrutzki, C.2    Wortelkamp, S.3    Sickmann, A.4    Zahedi, R.P.5
  • 42
    • 79961071855 scopus 로고    scopus 로고
    • Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes
    • Rowley JW, et al. Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes. Blood. 2011;118(14):e101-e111.
    • (2011) Blood , vol.118 , Issue.14 , pp. e101-e111
    • Rowley, J.W.1
  • 43
    • 0037105573 scopus 로고    scopus 로고
    • Normal Arp2/3 complex activation in platelets lacking WASp
    • Falet H, Hoffmeister KM, Neujahr R, Hartwig JH. Normal Arp2/3 complex activation in platelets lacking WASp. Blood. 2002;100(6):2113-2122.
    • (2002) Blood , vol.100 , Issue.6 , pp. 2113-2122
    • Falet, H.1    Hoffmeister, K.M.2    Neujahr, R.3    Hartwig, J.H.4
  • 44
    • 67849116915 scopus 로고    scopus 로고
    • Novel molecules in calcium signaling in platelets
    • Bergmeier W, Stefanini L. Novel molecules in calcium signaling in platelets. J Thromb Haemost. 2009;7(suppl 1):187-190.
    • (2009) J Thromb Haemost. , vol.7 , pp. 187-190
    • Bergmeier, W.1    Stefanini, L.2
  • 45
  • 46
    • 84863583482 scopus 로고    scopus 로고
    • Granule exocytosis is required for platelet spreading: Differential sorting of α-granules expressing VAMP-7
    • Peters CG, Michelson AD, Flaumenhaft R. Granule exocytosis is required for platelet spreading: differential sorting of α-granules expressing VAMP-7. Blood. 2012;120(1):199-206.
    • (2012) Blood , vol.120 , Issue.1 , pp. 199-206
    • Peters, C.G.1    Michelson, A.D.2    Flaumenhaft, R.3
  • 47
    • 84907495473 scopus 로고    scopus 로고
    • Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion
    • Zhu Q, et al. Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion. J Clin Invest. 2014;124(10):4503-4516.
    • (2014) J Clin Invest. , vol.124 , Issue.10 , pp. 4503-4516
    • Zhu, Q.1
  • 49
    • 81055145256 scopus 로고    scopus 로고
    • Tomosyn-dependent regulation of synaptic transmission is required for a late phase of associative odor memory
    • Chen K, Richlitzki A, Featherstone DE, Schwarzel M, Richmond JE. Tomosyn-dependent regulation of synaptic transmission is required for a late phase of associative odor memory. Proc Natl Acad Sci U S A. 2011;108(45):18482-18487.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.45 , pp. 18482-18487
    • Chen, K.1    Richlitzki, A.2    Featherstone, D.E.3    Schwarzel, M.4    Richmond, J.E.5
  • 50
    • 84878263829 scopus 로고    scopus 로고
    • Harnessing the platelet signaling network to produce an optimal hemostatic response
    • Brass LF, Tomaiuolo M, Stalker TJ. Harnessing the platelet signaling network to produce an optimal hemostatic response. Hematol Oncol Clin North Am. 2013;27(3):381-409.
    • (2013) Hematol Oncol Clin North Am. , vol.27 , Issue.3 , pp. 381-409
    • Brass, L.F.1    Tomaiuolo, M.2    Stalker, T.J.3
  • 51
    • 0030914460 scopus 로고    scopus 로고
    • Griscelli disease maps to chromosome 15q21 and is associated with mutations in the myosin-Va gene
    • Pastural E, et al. Griscelli disease maps to chromosome 15q21 and is associated with mutations in the myosin-Va gene. Nat Genet. 1997;16(3):289-292.
    • (1997) Nat Genet. , vol.16 , Issue.3 , pp. 289-292
    • Pastural, E.1
  • 52
    • 77957200674 scopus 로고    scopus 로고
    • A revised model for the secretion of tPA and cytokines from cultured endothelial cells
    • Knipe L, et al. A revised model for the secretion of tPA and cytokines from cultured endothelial cells. Blood. 2010;116(12):2183-2191.
    • (2010) Blood , vol.116 , Issue.12 , pp. 2183-2191
    • Knipe, L.1
  • 54
    • 0042178376 scopus 로고    scopus 로고
    • Granule stores from cellubrevin/VAMP-3 null mouse platelets exhibit normal stimulus-induced release
    • Schraw TD, et al. Granule stores from cellubrevin/VAMP-3 null mouse platelets exhibit normal stimulus-induced release. Blood. 2003;102(5):1716-1722.
    • (2003) Blood , vol.102 , Issue.5 , pp. 1716-1722
    • Schraw, T.D.1
  • 55
    • 33645736307 scopus 로고    scopus 로고
    • Arf6 plays an early role in platelet activation by collagen and convulxin
    • Choi W, Karim ZA, Whiteheart SW. Arf6 plays an early role in platelet activation by collagen and convulxin. Blood. 2006;107(8):3145-3152.
    • (2006) Blood , vol.107 , Issue.8 , pp. 3145-3152
    • Choi, W.1    Karim, Z.A.2    Whiteheart, S.W.3
  • 56
    • 0035075412 scopus 로고    scopus 로고
    • A tail vein bleeding time model and delayed bleeding in hemophiliac mice
    • Broze GJ Jr, Yin ZF, Lasky N. A tail vein bleeding time model and delayed bleeding in hemophiliac mice. Thromb Haemost. 2001;85(4):747-748.
    • (2001) Thromb Haemost. , vol.85 , Issue.4 , pp. 747-748
    • Broze, G.J.1    Yin, Z.F.2    Lasky, N.3
  • 57
    • 80053377119 scopus 로고    scopus 로고
    • Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation
    • Zhang G, et al. Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation. Blood. 2011;118(13):3670-3679.
    • (2011) Blood , vol.118 , Issue.13 , pp. 3670-3679
    • Zhang, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.