메뉴 건너뛰기




Volumn 11, Issue 4, 2015, Pages 670-684

Essential role for the ATG4b protease and autophagy in bleomycin-induced pulmonary fibrosis

Author keywords

ATG4B; Autophagin 1; Autophagy; Epithelial cell; Idiopathic pulmonary fibrosis; Lung fibrosis

Indexed keywords

AUTOPHAGY RELATED 4B; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG; ATG4B PROTEIN, MOUSE; AUTOPHAGY RELATED PROTEIN; BLEOMYCIN; CYSTEINE PROTEINASE; CYTOKINE;

EID: 84942511008     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2015.1034409     Document Type: Article
Times cited : (134)

References (61)
  • 1
    • 0035895243 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Prevailing and evolving hypotheses about its pathogenesis and implications for therapy
    • PMID:11177318
    • Selman M, King TE, Pardo A. Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med 2001; 134:136-51; PMID:11177318; http://dx.doi.org/10.7326/0003-4819-134-2-200101160-00015
    • (2001) Ann Intern Med , vol.134 , pp. 136-151
    • Selman, M.1    King, T.E.2    Pardo, A.3
  • 2
    • 82755161052 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis
    • PMID:21719092
    • King TE, Pardo A, Selman M. Idiopathic pulmonary fibrosis. Lancet 2011; 378:1949-61; PMID:21719092; http://dx.doi.org/10.1016/S0140-6736(11)60052-4
    • (2011) Lancet , vol.378 , pp. 1949-1961
    • King, T.E.1    Pardo, A.2    Selman, M.3
  • 3
    • 25444457220 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: An epithelial/fibroblastic cross-talk disorder
    • PMID:11806838
    • Selman M, Pardo A. Idiopathic pulmonary fibrosis: an epithelial/fibroblastic cross-talk disorder. Respir Res 2002; 3:3; PMID:11806838; http://dx.doi.org/10.1186/rr175
    • (2002) Respir Res , vol.3
    • Selman, M.1    Pardo, A.2
  • 4
    • 84863899808 scopus 로고    scopus 로고
    • Alveolar epithelial cell disintegrity and subsequent activation: A key process in pulmonary fibrosis
    • Selman M, Pardo A. Alveolar epithelial cell disintegrity and subsequent activation: a key process in pulmonary fibrosis. Am J RespirCrit Care Med 2012; 186:119-21; http://dx.doi.org/10.1164/rccm.201206-0997ED
    • (2012) Am J Respircrit Care Med , vol.186 , pp. 119-121
    • Selman, M.1    Pardo, A.2
  • 5
    • 77958147116 scopus 로고    scopus 로고
    • Aging and interstitial lung diseases: Unraveling an old forgotten player in the pathogenesis of lung fibrosis
    • Selman M, Rojas M, Mora AL, Pardo A. Aging and interstitial lung diseases: unraveling an old forgotten player in the pathogenesis of lung fibrosis. SeminRespirCrit Care Med 2010; 31:607-17
    • (2010) Seminrespircrit Care Med , vol.31 , pp. 607-617
    • Selman, M.1    Rojas, M.2    Mora, A.L.3    Pardo, A.4
  • 9
    • 84898639632 scopus 로고    scopus 로고
    • Atomistic autophagy: The structures of cellular self-digestion
    • PMID:24725401
    • Hurley JH, Schulman BA. Atomistic autophagy: the structures of cellular self-digestion. Cell 2014; 157:300-11; PMID:24725401; http://dx.doi.org/10.1016/j.cell.2014.01.070
    • (2014) Cell , vol.157 , pp. 300-311
    • Hurley, J.H.1    Schulman, B.A.2
  • 10
    • 77955964664 scopus 로고    scopus 로고
    • Selective autophagy regulates various cellular functions
    • PMID:20670274
    • Komatsu M, Ichimura Y. Selective autophagy regulates various cellular functions. Genes Cells 2010; 15:923-33; PMID:20670274; http://dx.doi.org/10.1111/j.1365-2443.2010.01433.x
    • (2010) Genes Cells , vol.15 , pp. 923-933
    • Komatsu, M.1    Ichimura, Y.2
  • 12
    • 84920380278 scopus 로고    scopus 로고
    • The functional and pathologic relevance of autophagy proteases
    • PMID:25654548
    • Fernandez AF, Lopez-Otın C. The functional and pathologic relevance of autophagy proteases. J Clin Invest 2015; 125:33-41; PMID:25654548; http://dx.doi.org/10.1172/JCI73940
    • (2015) J Clin Invest , vol.125 , pp. 33-41
    • Fernandez, A.F.1    Lopez-Otın, C.2
  • 13
    • 79953190772 scopus 로고    scopus 로고
    • Kinet- ics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates
    • PMID:21177865
    • Li M, Hou Y, Wang J, Chen X, Shao ZM, Yin XM. Kinet- ics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates. J Biol Chem 2011; 286:7327-38; PMID:21177865; http://dx.doi.org/10.1074/jbc.M110.199059 www.tandfonline.com
    • (2011) J Biol Chem , vol.286 , pp. 7327-7338
    • Li, M.1    Hou, Y.2    Wang, J.3    Chen, X.4    Shao, Z.M.5    Yin, X.M.6
  • 15
    • 78649338141 scopus 로고    scopus 로고
    • Autophagy and the integrated stress response
    • PMID:20965422
    • Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Mol Cell 2010; 40:280-93; PMID:20965422; http://dx.doi.org/10.1016/j.molcel.2010.09.023
    • (2010) Mol Cell , vol.40 , pp. 280-293
    • Kroemer, G.1    Marino, G.2    Levine, B.3
  • 16
    • 59249095218 scopus 로고    scopus 로고
    • Methods for monitoring autophagy using GFP-LC3 transgenic mice
    • PMID:19200873
    • Mizushima N. Methods for monitoring autophagy using GFP-LC3 transgenic mice. Methods Enzymol 2009; 452:13-23; PMID:19200873; http://dx.doi.org/10.1016/S0076-6879(08)03602-1
    • (2009) Methods Enzymol , vol.452 , pp. 13-23
    • Mizushima, N.1
  • 19
    • 13844314302 scopus 로고    scopus 로고
    • Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary fibrosis
    • PMID:15653994
    • Plataki M, Koutsopoulos AV, Darivianaki K, Delides G, Siafakas NM, Bouros D. Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary fibrosis. Chest 2005; 127:266-74; PMID:15653994; http://dx.doi.org/10.1378/chest.127.1.266
    • (2005) Chest , vol.127 , pp. 266-274
    • Plataki, M.1    Koutsopoulos, A.V.2    Darivianaki, K.3    Delides, G.4    Siafakas, N.M.5    Bouros, D.6
  • 20
    • 33646598090 scopus 로고    scopus 로고
    • Bleomycin initiates apoptosis of lung epithelial cells by ROS but not by Fas/Fas L pathway
    • PMID:16306138
    • Wallach-Dayan SB, Izbicki G, Cohen PY, Gerstl-Golan R, Fine A, Breuer R. Bleomycin initiates apoptosis of lung epithelial cells by ROS but not by Fas/Fas L pathway. Am J Physiol Lung Cell Mol Physiol 2006; 290: L790-L796; PMID:16306138; http://dx.doi.org/10.1152/ajplung.00300.2004
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.290 , pp. L790-L796
    • Wallach-Dayan, S.B.1    Izbicki, G.2    Cohen, P.Y.3    Gerstl-Golan, R.4    Fine, A.5    Breuer, R.6
  • 21
    • 84857335732 scopus 로고    scopus 로고
    • Autophagy in pulmonary diseases
    • PMID:22035347
    • Ryter SW, Nakahira K, Haspel JA, Choi AM. Autophagy in pulmonary diseases. Annu Rev Physiol 2012; 74:377-401; PMID:22035347; http://dx.doi.org/10.1146/annurev-physiol-020911-153348
    • (2012) Annu Rev Physiol , vol.74 , pp. 377-401
    • Ryter, S.W.1    Nakahira, K.2    Haspel, J.A.3    Choi, A.M.4
  • 22
    • 77953271787 scopus 로고    scopus 로고
    • Autophagy in the lung
    • PMID:20160144
    • Ryter SW, Choi AM. Autophagy in the lung. Proc Am Thorac Soc 2010; 7:13-21; PMID:20160144; http://dx.doi.org/10.1513/pats.200909-101JS
    • (2010) Proc am Thorac Soc , vol.7 , pp. 13-21
    • Ryter, S.W.1    Choi, A.M.2
  • 23
    • 84862295772 scopus 로고    scopus 로고
    • ATG5, autophagy and lung function in asthma
    • PMID:22498476
    • Poon A, Eidelman D, Laprise C, Hamid Q. ATG5, autophagy and lung function in asthma. Autophagy 2012; 8:694-5; PMID:22498476; http://dx.doi.org/10.4161/auto.19315
    • (2012) Autophagy , vol.8 , pp. 694-695
    • Poon, A.1    Eidelman, D.2    Laprise, C.3    Hamid, Q.4
  • 25
    • 80053070208 scopus 로고    scopus 로고
    • Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-beta1-dependent and -independent mechanisms
    • PMID:21841134
    • Mi S, Li Z, Yang HZ, Liu H, Wang JP, Ma YG, Wang XX, Liu HZ, Sun W, Hu ZW. Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-beta1-dependent and -independent mechanisms. J Immunol 2011; 187:3003-14; PMID:21841134; http://dx.doi.org/10.4049/jimmunol.1004081
    • (2011) J Immunol , vol.187 , pp. 3003-3014
    • Mi, S.1    Li, Z.2    Yang, H.Z.3    Liu, H.4    Wang, J.P.5    Ma, Y.G.6    Wang, X.X.7    Liu, H.Z.8    Sun, W.9    Hu, Z.W.10
  • 26
    • 83455230751 scopus 로고    scopus 로고
    • TLR4 activity is required in the resolution of pulmonary inflammation and fibrosis after acute and chronic lung injury
    • PMID:22062220
    • Yang HZ, Wang JP, Mi S, Liu HZ, Cui B, Yan HM, Yan J, Li Z, Liu H, Hua F, et al. TLR4 activity is required in the resolution of pulmonary inflammation and fibrosis after acute and chronic lung injury. Am J Pathol 2012; 180:275-92; PMID:22062220; http://dx.doi.org/10.1016/j.ajpath.2011.09.019
    • (2012) Am J Pathol , vol.180 , pp. 275-292
    • Yang, H.Z.1    Wang, J.P.2    Mi, S.3    Liu, H.Z.4    Cui, B.5    Yan, H.M.6    Yan, J.7    Li, Z.8    Liu, H.9    Hua, F.10
  • 27
    • 33645916698 scopus 로고    scopus 로고
    • Inositol and IP3 levels regulate autophagy: Biology and therapeutic speculations
    • Sarkar S, Rubinsztein DC. Inositol and IP3 levels regulate autophagy: biology and therapeutic speculations. Autophagy 2006; 2(2):132-4; http://dx.doi.org/10.4161/auto.2387
    • (2006) Autophagy , vol.2 , Issue.2 , pp. 132-134
    • Sarkar, S.1    Rubinsztein, D.C.2
  • 28
    • 84906222771 scopus 로고    scopus 로고
    • Fertilization-induced autophagy in mouse embryos is indepen- dent of mTORC1
    • Yamamoto A, Mizushima N, Tsukamoto S. Fertilization-induced autophagy in mouse embryos is indepen- dent of mTORC1. Biol Reprod 2014; 91(1):7; http://dx.doi.org/10.1095/biolreprod.113.115816
    • (2014) Biol Reprod , vol.91 , Issue.1
    • Yamamoto, A.1    Mizushima, N.2    Tsukamoto, S.3
  • 29
    • 77954898129 scopus 로고    scopus 로고
    • A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions
    • Lipinski MM, Hoffman G, Ng A, Zhou W, Py BF, Hsu E, Liu X, Eisenberg J, Liu J, Blenis J, Xavier RJ, Yuan J. A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions. Dev Cell 2010; 18(6):1041-52; http://dx.doi.org/10.1016/j.devcel.2010.05.005
    • (2010) Dev Cell , vol.18 , Issue.6 , pp. 1041-1052
    • Lipinski, M.M.1    Hoffman, G.2    Ng, A.3    Zhou, W.4    Py, B.F.5    Hsu, E.6    Liu, X.7    Eisenberg, J.8    Liu, J.9    Blenis, J.10    Xavier, R.J.11    Yuan, J.12
  • 30
    • 4344604111 scopus 로고    scopus 로고
    • HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3-and GABAA receptor-associated protein-phospholipid conjugates
    • PMID:15187094
    • Tanida I, Sou YS, Ezaki J, Minematsu-Ikeguchi N, Ueno T, Kominami E. HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3-and GABAA receptor-associated protein-phospholipid conjugates. J Biol Chem 2004; 279:36268-76; PMID:15187094; http://dx.doi.org/10.1074/jbc.M401461200
    • (2004) J Biol Chem , vol.279 , pp. 36268-36276
    • Tanida, I.1    Sou, Y.S.2    Ezaki, J.3    Minematsu-Ikeguchi, N.4    Ueno, T.5    Kominami, E.6
  • 32
    • 84896711467 scopus 로고    scopus 로고
    • IL-17A promotes the exacerbation of IL-33-induced airway hyperresponsive- ness by enhancing neutrophilicinflammation via CXCR2 signaling in mice
    • PMID:24446518
    • Mizutani N, Nabe T, Yoshino S. IL-17A promotes the exacerbation of IL-33-induced airway hyperresponsive- ness by enhancing neutrophilicinflammation via CXCR2 signaling in mice. J Immunol 2014; 192:1372-84; PMID:24446518; http://dx.doi.org/10.4049/jimmunol.1301538
    • (2014) J Immunol , vol.192 , pp. 1372-1384
    • Mizutani, N.1    Nabe, T.2    Yoshino, S.3
  • 35
    • 0035808784 scopus 로고    scopus 로고
    • Interleukin 12 p40 production by barrier epithelial cells during airway inflammation
    • PMID:11157054
    • Walter MJ, Kajiwara N, Karanja P, Castro M, Holtzman MJ. Interleukin 12 p40 production by barrier epithelial cells during airway inflammation. J Exp Med 2001; 193:339-51; PMID:11157054; http://dx.doi.org/10.1084/jem.193.3.339
    • (2001) J Exp Med , vol.193 , pp. 339-351
    • Walter, M.J.1    Kajiwara, N.2    Karanja, P.3    Castro, M.4    Holtzman, M.J.5
  • 38
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad- independent pathways in TGF-beta family signalling
    • PMID:14534577
    • Derynck R, Zhang YE. Smad-dependent and Smad- independent pathways in TGF-beta family signalling. Nature 2003; 425:577-84; PMID:14534577; http://dx.doi.org/10.1038/nature02006
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 41
    • 30044449492 scopus 로고    scopus 로고
    • IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis
    • PMID:16327802
    • Fichtner-Feigl S, Strober W, Kawakami K, Puri RK, Kitani A. IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis. Nat Med 2006; 12:99-106; PMID:16327802; http://dx.doi.org/10.1038/nm1332
    • (2006) Nat Med , vol.12 , pp. 99-106
    • Fichtner-Feigl, S.1    Strober, W.2    Kawakami, K.3    Puri, R.K.4    Kitani, A.5
  • 46
    • 84882616856 scopus 로고    scopus 로고
    • Role of caveolin-1 in fibrotic diseases
    • PMID:23583521
    • Gvaramia D, Blaauboer ME, Hanemaaijer R, Everts V. Role of caveolin-1 in fibrotic diseases. Matrix Biol 2013; 32:307-15; PMID:23583521; http://dx.doi.org/10.1016/j.matbio.2013.03.005
    • (2013) Matrix Biol , vol.32 , pp. 307-315
    • Gvaramia, D.1    Blaauboer, M.E.2    Hanemaaijer, R.3    Everts, V.4
  • 48
    • 0035964954 scopus 로고    scopus 로고
    • Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice
    • PMID:11498544
    • Drab M, Verkade P, Elger M, Kasper M, Lohn M, Lauterbach B, Menne J, Lindschau C, Mende F, Luft FC, et al. Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice. Science 2001; 293:2449-52; PMID:11498544; http://dx.doi.org/10.1126/science.1062688
    • (2001) Science , vol.293 , pp. 2449-2452
    • Drab, M.1    Verkade, P.2    Elger, M.3    Kasper, M.4    Lohn, M.5    Lauterbach, B.6    Menne, J.7    Lindschau, C.8    Mende, F.9    Luft, F.C.10
  • 49
    • 34249933120 scopus 로고    scopus 로고
    • Expression of Caveolin-1 reduces cellular responses to TGF-beta1 through down-regulating the expression of TGF-beta type II receptor gene in NIH3T3 fibroblast cells
    • PMID:17543885
    • Lee EK, Lee YS, Han IO, Park SH. Expression of Caveolin-1 reduces cellular responses to TGF-beta1 through down-regulating the expression of TGF-beta type II receptor gene in NIH3T3 fibroblast cells. Biochem Biophys Res Commun 2007; 359:385-90; PMID:17543885; http://dx.doi.org/10.1016/j.bbrc.2007.05.121
    • (2007) Biochem Biophys Res Commun , vol.359 , pp. 385-390
    • Lee, E.K.1    Lee, Y.S.2    Han, I.O.3    Park, S.H.4
  • 50
    • 84903820951 scopus 로고    scopus 로고
    • Autophagy: An integral component of the mammalian stress response
    • PMID:24358454
    • Ryter SW, Choi AM. Autophagy: an integral component of the mammalian stress response. J Biochem Pharmacol Res 2013; 1:176-88; PMID:24358454
    • (2013) J Biochem Pharmacol Res , vol.1 , pp. 176-188
    • Ryter, S.W.1    Choi, A.M.2
  • 51
    • 41449109334 scopus 로고    scopus 로고
    • Induction of autophagy during extracellular matrix detachment promotes cell survival
    • PMID:18094039
    • Fung C, Lock R, Gao S, Salas E, Debnath J. Induction of autophagy during extracellular matrix detachment promotes cell survival. Mol Biol Cell 2008; 19:797-806; PMID:18094039; http://dx.doi.org/10.1091/mbc.E07-10-1092
    • (2008) Mol Biol Cell , vol.19 , pp. 797-806
    • Fung, C.1    Lock, R.2    Gao, S.3    Salas, E.4    Debnath, J.5
  • 54
    • 0037369314 scopus 로고    scopus 로고
    • Bleomycin-induced apoptosis of alveolar epithe- lialcells requires angiotensin synthesis de novo
    • PMID:12573988
    • Li X, Zhang H, Soledad-Conrad V, Zhuang J, Uhal BD. Bleomycin-induced apoptosis of alveolar epithe- lialcells requires angiotensin synthesis de novo. Am J Physiol Lung Cell Mol Physiol 2003; 284: L501-7; PMID:12573988; http://dx.doi.org/10.1152/ajplung.00273.2002
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.284 , pp. L501-L557
    • Li, X.1    Zhang, H.2    Soledad-Conrad, V.3    Zhuang, J.4    Uhal, B.D.5
  • 56
  • 57
    • 18744383614 scopus 로고    scopus 로고
    • Matrilysin shedding of syndecan1 regulates chemokine mobiliza- tion and transepithelial efflux of neutrophils in acute lung injury
    • PMID:12464176
    • Li Q, Park PW, Wilson CL, Parks WC. Matrilysin shedding of syndecan1 regulates chemokine mobiliza- tion and transepithelial efflux of neutrophils in acute lung injury. Cell 2002; 111:635-46; PMID:12464176; http://dx.doi.org/10.1016/S0092-8674(02)01079-6
    • (2002) Cell , vol.111 , pp. 635-646
    • Li, Q.1    Park, P.W.2    Wilson, C.L.3    Parks, W.C.4
  • 58
    • 84866093953 scopus 로고    scopus 로고
    • Autophagy genes promote apoptotic cell corpse clearance
    • Zou W, Wang X, Vale RD, Ou G. Autophagy genes promote apoptotic cell corpse clearance. Autophagy 2012; 8(8):1267-8; http://dx.doi.org/10.4161/auto.20786
    • (2012) Autophagy , vol.8 , Issue.8 , pp. 1267-1268
    • Zou, W.1    Wang, X.2    Vale, R.D.3    Ou, G.4
  • 59
    • 84894565195 scopus 로고    scopus 로고
    • Self-consumption: The interplay of autophagy and apoptosis
    • Marino G, Niso-Santano M, Baehrecke EH, Kroemer G. Self-consumption: the interplay of autophagy and apoptosis. Nat Rev Mol Cell Biol 2014; 15(2):81-94; http://dx.doi.org/10.1038/nrm3735
    • (2014) Nat Rev Mol Cell Biol , vol.15 , Issue.2 , pp. 81-94
    • Marino, G.1    Niso-Santano, M.2    Baehrecke, E.H.3    Kroemer, G.4
  • 60
    • 80054825045 scopus 로고    scopus 로고
    • Microtubule-associated protein 1 light chain 3 alpha (LC3) associated phagocytosis is required for the efficient clearance of dead cells
    • Martinez J, Almendinger J, Oberst A, Ness R, Dillon CP, Fitzgerald P, Hengartner MO, Green DR. Microtubule-associated protein 1 light chain 3 alpha (LC3) associated phagocytosis is required for the efficient clearance of dead cells. Proc Natl Acad Sci U S A 2011; 108(42):17396-401; http://dx.doi.org/10.1073/pnas.1113421108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.42 , pp. 17396-17401
    • Martinez, J.1    Almendinger, J.2    Oberst, A.3    Ness, R.4    Dillon, C.P.5    Fitzgerald, P.6    Hengartner, M.O.7    Green, D.R.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.