Bleomycin initiates apoptosis of lung epithelial cells by ROS but not by Fas/FasL pathway

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 290, Issue 4, 2006, Pages

  Wallach Dayan, Shulamit B ^a   Izbicki, Gabriel ^a   Cohen, Pazit Y ^a   Gerstl Golan, Regina ^a   Fine, Alan ^b   Breuer, Raphael ^a,b  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Fas ligand; Reactive oxygen species

Indexed keywords

BLEOMYCIN; CASPASE 8; CASPASE 8 INHIBITOR; CASPASE 9; CASPASE 9 INHIBITOR; FAS ANTIGEN; FAS LIGAND; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; ANTINEOPLASTIC ANTIMETABOLITE; CASP8 PROTEIN, MOUSE; CASP9 PROTEIN, MOUSE; CASPASE; ENZYME INHIBITOR; FASL PROTEIN, MOUSE; MEMBRANE PROTEIN; TUMOR NECROSIS FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EPITHELIUM CELL; IN VITRO STUDY; LUNG ALVEOLUS EPITHELIUM; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL TOXICITY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; UPREGULATION; ANIMAL; CELL LINE; CELL MEMBRANE POTENTIAL; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; LUNG; METABOLISM; MITOCHONDRION; PHYSIOLOGY;

ANIMALS; ANTIGENS, CD95; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; BLEOMYCIN; CASPASE 8; CASPASE 9; CASPASES; CELL DEATH; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; EPITHELIAL CELLS; FAS LIGAND PROTEIN; GLUTATHIONE; LUNG; MEMBRANE GLYCOPROTEINS; MEMBRANE POTENTIALS; MICE; MITOCHONDRIA; REACTIVE OXYGEN SPECIES; TUMOR NECROSIS FACTORS; UP-REGULATION;

EID: 33646598090     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00300.2004     Document Type: Article

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