Nrf2-heme oxygenase-1 axis in mucoepidermoid carcinoma of the lung: Antitumoral effects associated with down-regulation of matrix metalloproteinases

Free Radical Biology and Medicine

Volumn 89, Issue , 2015, Pages 147-157

  Tertil, Magdalena ^a,b,c   Golda, Slawomir ^a,c   Skrzypek, Klaudia ^a,b,d   Florczyk, Urszula ^a   Weglarczyk, Kazimierz ^b,e   Kotlinowski, Jerzy ^a   Maleszewska, Monika ^a,f   Czauderna, Szymon ^a   Pichon, Chantal ^b   Kieda, Claudine ^a,b   Jozkowicz, Alicja ^a   Dulak, Jozef ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

^b CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

^c INSTITUTE OF PHARMACOLOGY   (Poland)

^d JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^e JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^f MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING   (Germany)

Author keywords

Heme oxygenase 1; Matrix metalloproteinases; MMP 1; Mucoepidermoid carcinoma; Non small cell lung cancer; Nrf2; Nuclear factor (erythroid derived 2) like 2

Indexed keywords

HEME OXYGENASE 1; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; TRANSCRIPTION FACTOR NRF2; MESSENGER RNA;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; DOWN REGULATION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; LUNG MUCOEPIDERMOID CARCINOMA; MALE; MOUSE; NON SMALL CELL LUNG CANCER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR MICROENVIRONMENT; ANIMAL; APOPTOSIS; CARCINOMA, MUCOEPIDERMOID; CARCINOMA, NON-SMALL-CELL LUNG; DRUG SCREENING; ENZYME IMMUNOASSAY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; LUNG NEOPLASMS; METABOLISM; NONOBESE DIABETIC MOUSE; OXIDATIVE STRESS; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCID MOUSE; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, MUCOEPIDERMOID; CARCINOMA, NON-SMALL-CELL LUNG; CELL PROLIFERATION; DOWN-REGULATION; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HEME OXYGENASE-1; HUMANS; IMMUNOENZYME TECHNIQUES; LUNG NEOPLASMS; MALE; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED NOD; MICE, SCID; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; TUMOR MICROENVIRONMENT; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84942422746     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.08.004     Document Type: Article

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