메뉴 건너뛰기




Volumn 35, Issue 6, 2012, Pages 461-471

High expression of heme oxygenase-1 is associated with tumor invasiveness and poor clinical outcome in non-small cell lung cancer patients

Author keywords

Heme Oxygenase 1; Metastasis; Non small cell lung cancer; Prognosis

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; API 59; CD147 ANTIGEN; GELATINASE B; HEME OXYGENASE 1; PROTEIN KINASE B INHIBITOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; TUMOR MARKER;

EID: 84879216859     PISSN: 22113428     EISSN: 22113436     Source Type: Journal    
DOI: 10.1007/s13402-012-0105-5     Document Type: Article
Times cited : (85)

References (52)
  • 1
    • 0023731036 scopus 로고
    • Heme oxygenase: Function, multiplicity, regulatory mechanisms, and clinical applications
    • M.D. Maines, Heme oxygenase: Function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J. 2, 2557-2568 (1988)
    • (1988) FASEB J. , vol.2 , pp. 2557-2568
    • Maines, M.D.1
  • 2
    • 34250193619 scopus 로고    scopus 로고
    • Colonic expression of heme oxygenase-1 is associated with a better long-term survival in patients with colorectal cancer
    • J.C. Becker, H. Fukui, Y. Imai, A. Sekikawa, T. Kimura, H. Yamagishi et al., Colonic expression of heme oxygenase-1 is associated with a better long-term survival in patients with colorectal cancer. Scand. J. Gastroenterol. 42, 852-858 (2007)
    • (2007) Scand. J. Gastroenterol. , vol.42 , pp. 852-858
    • Becker, J.C.1    Fukui, H.2    Imai, Y.3    Sekikawa, A.4    Kimura, T.5    Yamagishi, H.6
  • 3
    • 0030923630 scopus 로고    scopus 로고
    • The heme oxygenase system: A regulator of second messenger gases
    • M.D. Maines, The heme oxygenase system: A regulator of second messenger gases. Annu. Rev. Pharmacol. Toxicol. 37, 517-554 (1997)
    • (1997) Annu. Rev. Pharmacol. Toxicol. , vol.37 , pp. 517-554
    • Maines, M.D.1
  • 4
    • 0038745911 scopus 로고    scopus 로고
    • Heme oxygenase-1 in growth control and its clinical application to vascular disease
    • W. Durante, Heme oxygenase-1 in growth control and its clinical application to vascular disease. J. Cell. Physiol. 195, 373-382 (2003)
    • (2003) J. Cell. Physiol. , vol.195 , pp. 373-382
    • Durante, W.1
  • 7
    • 77955900385 scopus 로고    scopus 로고
    • Heme induces DNA damage and hyperproliferation of colonic epithelial cells via hydrogen peroxide produced by heme oxygenase: A possible mechanism of heme-induced colon cancer
    • S. Ishikawa, S. Tamaki, M. Ohata, K. Arihara, M. Itoh, Heme induces DNA damage and hyperproliferation of colonic epithelial cells via hydrogen peroxide produced by heme oxygenase: A possible mechanism of heme-induced colon cancer. Mol. Nutr. Food. Res. 54, 1182-1191 (2010)
    • (2010) Mol. Nutr. Food. Res. , vol.54 , pp. 1182-1191
    • Ishikawa, S.1    Tamaki, S.2    Ohata, M.3    Arihara, K.4    Itoh, M.5
  • 8
    • 0042737675 scopus 로고    scopus 로고
    • Different effects of constitutive nitric oxide synthase and heme oxygenase on pulmonary or liver metastasis of colon cancer in mice
    • T. Ishikawa, N. Yoshida, H. Higashihara, M. Inoue, K. Uchiyama, T. Takagi et al., Different effects of constitutive nitric oxide synthase and heme oxygenase on pulmonary or liver metastasis of colon cancer in mice. Clinical & experimental metastasis. 20, 445-450 (2003)
    • (2003) Clinical & experimental metastasis. , vol.20 , pp. 445-450
    • Ishikawa, T.1    Yoshida, N.2    Higashihara, H.3    Inoue, M.4    Uchiyama, K.5    Takagi, T.6
  • 9
    • 72449123797 scopus 로고    scopus 로고
    • Critical role of endogenous heme oxygenase 1 as a tuner of the invasive potential of prostate cancer cells
    • G. Gueron, A. De Siervi, M. Ferrando, M. Salierno, P. De Luca, B. Elguero et al., Critical role of endogenous heme oxygenase 1 as a tuner of the invasive potential of prostate cancer cells. Mol. Cancer Res. 7, 1745-1755 (2009)
    • (2009) Mol. Cancer Res. , vol.7 , pp. 1745-1755
    • Gueron, G.1    De Siervi, A.2    Ferrando, M.3    Salierno, M.4    De Luca, P.5    Elguero, B.6
  • 10
    • 70350221874 scopus 로고    scopus 로고
    • A novel experimental heme oxygenase-1-targeted therapy for hormone-refractory prostate cancer
    • M.A. Alaoui-Jamali, T.A. Bismar, A. Gupta, W.A. Szarek, J. Su, W. Song et al., A novel experimental heme oxygenase-1-targeted therapy for hormone-refractory prostate cancer. Cancer Res. 69, 8017-8024 (2009)
    • (2009) Cancer Res. , vol.69 , pp. 8017-8024
    • Alaoui-Jamali, M.A.1    Bismar, T.A.2    Gupta, A.3    Szarek, W.A.4    Su, J.5    Song, W.6
  • 11
    • 41149177653 scopus 로고    scopus 로고
    • Suppression of Nrf2-driven heme oxygenase-1 enhances the chemosensitivity of lung cancer A549 cells toward cisplatin
    • H.R. Kim, S. Kim, E.J. Kim, J.H. Park, S.H. Yang, E.T. Jeong et al., Suppression of Nrf2-driven heme oxygenase-1 enhances the chemosensitivity of lung cancer A549 cells toward cisplatin. Lung Cancer 60, 47-56 (2008)
    • (2008) Lung Cancer , vol.60 , pp. 47-56
    • Kim, H.R.1    Kim, S.2    Kim, E.J.3    Park, J.H.4    Yang, S.H.5    Jeong, E.T.6
  • 12
    • 33845696649 scopus 로고    scopus 로고
    • Inhibition of heme oxygenase-1 by zinc protoporphyrin IX reduces tumor growth of LL/2 lung cancer in C57BL mice
    • K. Hirai, T. Sasahira, H. Ohmori, K. Fujii, H. Kuniyasu, Inhibition of heme oxygenase-1 by zinc protoporphyrin IX reduces tumor growth of LL/2 lung cancer in C57BL mice. Int. J. Cancer 120, 500-505 (2007)
    • (2007) Int. J. Cancer , vol.120 , pp. 500-505
    • Hirai, K.1    Sasahira, T.2    Ohmori, H.3    Fujii, K.4    Kuniyasu, H.5
  • 13
    • 38649140658 scopus 로고    scopus 로고
    • Decreased heme-oxygenase (HO)-1 in the macrophages of non-small cell lung cancer
    • P. Boschetto, E. Zeni, L. Mazzetti, D. Miotto, N. Lo Cascio, P. Maestrelli et al., Decreased heme-oxygenase (HO)-1 in the macrophages of non-small cell lung cancer. Lung Cancer 59, 192-197 (2008)
    • (2008) Lung Cancer , vol.59 , pp. 192-197
    • Boschetto, P.1    Zeni, E.2    Mazzetti, L.3    Miotto, D.4    Lo Cascio, N.5    Maestrelli, P.6
  • 14
    • 84861730556 scopus 로고    scopus 로고
    • Expression of heme oxygenase-1 in non-small cell lung cancer (NSCLC) and its correlation with clinical data
    • M.S. Degese, J.E. Mendizabal, N.A. Gandini, J.S. Gutkind, A. Molinolo, S.M. Hewitt et al., Expression of heme oxygenase-1 in non-small cell lung cancer (NSCLC) and its correlation with clinical data. Lung Cancer 77, 168-175 (2012)
    • (2012) Lung Cancer , vol.77 , pp. 168-175
    • Degese, M.S.1    Mendizabal, J.E.2    Gandini, N.A.3    Gutkind, J.S.4    Molinolo, A.5    Hewitt, S.M.6
  • 15
    • 35848942608 scopus 로고    scopus 로고
    • Heme oxygenase-1 in tumors: Is it a false friend?
    • A. Jozkowicz, H. Was, J. Dulak, Heme oxygenase-1 in tumors: Is it a false friend? Antioxid. Redox. Signal. 9, 2099-2117 (2007)
    • (2007) Antioxid. Redox. Signal. , vol.9 , pp. 2099-2117
    • Jozkowicz, A.1    Was, H.2    Dulak, J.3
  • 16
    • 2342492317 scopus 로고    scopus 로고
    • Review of epidermal growth factor receptor biology
    • R.S. Herbst, Review of epidermal growth factor receptor biology. Int. J. Radiat. Oncol. Biol. Phys. 59, 21-26 (2004)
    • (2004) Int. J. Radiat. Oncol. Biol. Phys. , vol.59 , pp. 21-26
    • Herbst, R.S.1
  • 18
    • 76049104005 scopus 로고    scopus 로고
    • CD147/basigin promotes progression of malignant melanoma and other cancers
    • T. Kanekura, X. Chen, CD147/basigin promotes progression of malignant melanoma and other cancers. J. Dermatol. Sci. 57, 149-154 (2010)
    • (2010) J. Dermatol. Sci. , vol.57 , pp. 149-154
    • Kanekura, T.1    Chen, X.2
  • 19
    • 34250854097 scopus 로고    scopus 로고
    • HAb18G/CD147 functions in invasion and metastasis of hepatocellular carcinoma
    • J. Xu, H.Y. Xu, Q. Zhang, F. Song, J.L. Jiang, X.M. Yang et al., HAb18G/CD147 functions in invasion and metastasis of hepatocellular carcinoma. Mol. Cancer Res. 5, 605-614 (2007)
    • (2007) Mol. Cancer Res. , vol.5 , pp. 605-614
    • Xu, J.1    Xu, H.Y.2    Zhang, Q.3    Song, F.4    Jiang, J.L.5    Yang, X.M.6
  • 21
    • 79952276580 scopus 로고    scopus 로고
    • Heme oxygenase-1 in tumor biology and therapy
    • H. Was, J. Dulak, A. Jozkowicz, Heme oxygenase-1 in tumor biology and therapy. Current drug targets. 11, 1551-1570 (2010)
    • (2010) Current drug targets. , vol.11 , pp. 1551-1570
    • Was, H.1    Dulak, J.2    Jozkowicz, A.3
  • 22
    • 35848932314 scopus 로고    scopus 로고
    • Overexpression of heme oxygenase-1 in murine melanoma: Increased proliferation and viability of tumor cells, decreased survival of mice
    • H. Was, T. Cichon, R. Smolarczyk, D. Rudnicka, M. Stopa, C. Chevalier et al., Overexpression of heme oxygenase-1 in murine melanoma: Increased proliferation and viability of tumor cells, decreased survival of mice. Am. J. Pathol. 169, 2181-2198 (2006)
    • (2006) Am. J. Pathol. , vol.169 , pp. 2181-2198
    • Was, H.1    Cichon, T.2    Smolarczyk, R.3    Rudnicka, D.4    Stopa, M.5    Chevalier, C.6
  • 23
    • 0033606105 scopus 로고    scopus 로고
    • Heme oxygenase-1 expression in oral squamous cell carcinoma as involved in lymph node metastasis
    • M.H. Tsuji, T. Yanagawa, S. Iwasa, K. Tabuchi, K. Onizawa, S. Bannai et al., Heme oxygenase-1 expression in oral squamous cell carcinoma as involved in lymph node metastasis. Cancer Lett. 138, 53-59 (1999)
    • (1999) Cancer Lett. , vol.138 , pp. 53-59
    • Tsuji, M.H.1    Yanagawa, T.2    Iwasa, S.3    Tabuchi, K.4    Onizawa, K.5    Bannai, S.6
  • 25
    • 38649140658 scopus 로고    scopus 로고
    • Decreased heme-oxygenase (HO)-1 in the macrophages of non-small cell lung cancer
    • P. Boschetto, E. Zeni, L. Mazzetti, D. Miotto, N.L. Cascio, P. Maestrelli et al., Decreased heme-oxygenase (HO)-1 in the macrophages of non-small cell lung cancer. Lung Cancer 59, 192-197 (2008)
    • (2008) Lung Cancer , vol.59 , pp. 192-197
    • Boschetto, P.1    Zeni, E.2    Mazzetti, L.3    Miotto, D.4    Cascio, N.L.5    Maestrelli, P.6
  • 26
    • 33644838918 scopus 로고    scopus 로고
    • Involvement of Nrf2, p38, B-Raf, and nuclear factor-kappaB, but not phosphatidylinositol 3-kinase, in induction of hemeoxygenase-1 by dietary polyphenols
    • C.K. Andreadi, L.M. Howells, P.A. Atherfold, M.M. Manson, Involvement of Nrf2, p38, B-Raf, and nuclear factor-kappaB, but not phosphatidylinositol 3-kinase, in induction of hemeoxygenase-1 by dietary polyphenols. Mol. Pharmacol. 69, 1033-1040 (2006)
    • (2006) Mol. Pharmacol. , vol.69 , pp. 1033-1040
    • Andreadi, C.K.1    Howells, L.M.2    Atherfold, P.A.3    Manson, M.M.4
  • 27
    • 33947144570 scopus 로고    scopus 로고
    • Induction of heme-oxygenase 1 requires the p38MAPK and PI3K pathways and suppresses apoptotic cell death following hypericin-mediated photodynamic therapy
    • S. Kocanova, E. Buytaert, J.Y. Matroule, J. Piette, J. Golab, P. de Witte et al., Induction of heme-oxygenase 1 requires the p38MAPK and PI3K pathways and suppresses apoptotic cell death following hypericin-mediated photodynamic therapy. Apoptosis 12, 731-741 (2007)
    • (2007) Apoptosis , vol.12 , pp. 731-741
    • Kocanova, S.1    Buytaert, E.2    Matroule, J.Y.3    Piette, J.4    Golab, J.5    De Witte, P.6
  • 28
    • 35848954977 scopus 로고    scopus 로고
    • Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H:quinone oxidoreductase as a potential target
    • E.J. Joung, M.H. Li, H.G. Lee, N. Somparn, Y.S. Jung, H.K. Na et al., Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H:quinone oxidoreductase as a potential target. Antioxid. Redox. Signal. 9, 2087-2098 (2007)
    • (2007) Antioxid. Redox. Signal. , vol.9 , pp. 2087-2098
    • Joung, E.J.1    Li, M.H.2    Lee, H.G.3    Somparn, N.4    Jung, Y.S.5    Na, H.K.6
  • 29
    • 0030912190 scopus 로고    scopus 로고
    • Revisions in the international system for staging lung cancer
    • C.F. Mountain, Revisions in the International System for Staging Lung Cancer. Chest 111, 1710-1717 (1997)
    • (1997) Chest , vol.111 , pp. 1710-1717
    • Mountain, C.F.1
  • 30
  • 31
    • 0037158896 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in pulmonary adenocarcinoma by using cDNA array
    • H. Wikman, E. Kettunen, J.K. Seppanen, A. Karjalainen, J. Hollmen, S. Anttila et al., Identification of differentially expressed genes in pulmonary adenocarcinoma by using cDNA array. Oncogene 21, 5804-5813 (2002)
    • (2002) Oncogene , vol.21 , pp. 5804-5813
    • Wikman, H.1    Kettunen, E.2    Seppanen, J.K.3    Karjalainen, A.4    Hollmen, J.5    Anttila, S.6
  • 32
    • 35348943298 scopus 로고    scopus 로고
    • Carvedilol, a pharmacological antioxidant, inhibits neointimal matrix metalloproteinase-2 and 9 in experimental atherosclerosis
    • T.C. Wu, Y.H. Chen, H.B. Leu, Y.L. Chen, F.Y. Lin, S.J. Lin et al., Carvedilol, a pharmacological antioxidant, inhibits neointimal matrix metalloproteinase-2 and 9 in experimental atherosclerosis. Free Radic. Biol. Med. 43, 1508-1522 (2007)
    • (2007) Free Radic. Biol. Med. , vol.43 , pp. 1508-1522
    • Wu, T.C.1    Chen, Y.H.2    Leu, H.B.3    Chen, Y.L.4    Lin, F.Y.5    Lin, S.J.6
  • 33
    • 33846443173 scopus 로고    scopus 로고
    • Salvianolic acid B attenuates MMP-2 and MMP-9 expression in vivo in apolipoprotein-E-deficient mouse aorta and in vitro in LPStreated human aortic smooth muscle cells
    • S.J. Lin, I.T. Lee, Y.H. Chen, F.Y. Lin, L.M. Sheu, H.H. Ku et al., Salvianolic acid B attenuates MMP-2 and MMP-9 expression in vivo in apolipoprotein-E-deficient mouse aorta and in vitro in LPStreated human aortic smooth muscle cells. J. Cell. Biochem. 100, 372-384 (2007)
    • (2007) J. Cell. Biochem. , vol.100 , pp. 372-384
    • Lin, S.J.1    Lee, I.T.2    Chen, Y.H.3    Lin, F.Y.4    Sheu, L.M.5    Ku, H.H.6
  • 34
    • 79961159843 scopus 로고    scopus 로고
    • Subamolide E from Cinnamomum subavenium induces sub-G1 cell-cycle arrest and caspase-dependent apoptosis and reduces the migration ability of human melanoma cells
    • H.M. Wang, C.C. Chiu, P.F. Wu, C.Y. Chen, Subamolide E from Cinnamomum subavenium induces sub-G1 cell-cycle arrest and caspase-dependent apoptosis and reduces the migration ability of human melanoma cells. J. Agric. Food Chem. 59, 8187-8192 (2011)
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 8187-8192
    • Wang, H.M.1    Chiu, C.C.2    Wu, P.F.3    Chen, C.Y.4
  • 36
    • 34347234200 scopus 로고    scopus 로고
    • The chemoinvasion assay: A method to assess tumor and endothelial cell invasion and its modulation
    • 504-11
    • A. Albini, R. Benelli, The chemoinvasion assay: A method to assess tumor and endothelial cell invasion and its modulation. Nat. Protoc. 2(504-11) (2007)
    • (2007) Nat. Protoc. , vol.2
    • Albini, A.1    Benelli, R.2
  • 37
    • 0030689728 scopus 로고    scopus 로고
    • Requirement for protein kinase C theta for cell cycle progression and formation of actin stress fibers and filopodia in vascular endothelial cells
    • S. Tang, K.G. Morgan, C. Parker, J.A. Ware, Requirement for protein kinase C theta for cell cycle progression and formation of actin stress fibers and filopodia in vascular endothelial cells. J. Biol. Chem. 272, 28704-28711 (1997)
    • (1997) J. Biol. Chem. , vol.272 , pp. 28704-28711
    • Tang, S.1    Morgan, K.G.2    Parker, C.3    Ware, J.A.4
  • 38
    • 16544374489 scopus 로고    scopus 로고
    • Molecular basis of cellular response to cisplatin chemotherapy in non-small cell lung cancer (Review
    • G. Wang, E. Reed, Q.Q. Li, Molecular basis of cellular response to cisplatin chemotherapy in non-small cell lung cancer (Review). Oncol. Rep. 12, 955-965 (2004)
    • (2004) Oncol. Rep. , vol.12 , pp. 955-965
    • Wang, G.1    Reed, E.2    Li, Q.Q.3
  • 39
    • 80053239972 scopus 로고    scopus 로고
    • Distinct functional roles of akt isoforms for proliferation survival migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells
    • N. Grabinski, K. Bartkowiak, K. Grupp, B. Brandt, K. Pantel, M. Jucker, Distinct functional roles of Akt isoforms for proliferation, survival, migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells. Cell. Signal. 23, 1952-1960 (2011)
    • (2011) Cell. Signal. , vol.23 , pp. 1952-1960
    • Grabinski, N.1    Bartkowiak, K.2    Grupp, K.3    Brandt, B.4    Pantel, K.5    Jucker, M.6
  • 41
    • 0014348401 scopus 로고
    • The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase
    • R. Tenhunen, H.S. Marver, R. Schmid, The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc. Natl. Acad. Sci. U. S. A. 61, 748-755 (1968)
    • (1968) Proc. Natl. Acad. Sci. U. S. A. , vol.61 , pp. 748-755
    • Tenhunen, R.1    Marver, H.S.2    Schmid, R.3
  • 42
    • 0032778341 scopus 로고    scopus 로고
    • Induction of haem oxygenase-1 nitric oxide and ischaemia in experimental solid tumours and implications for tumour growth
    • K. Doi, T. Akaike, S. Fujii, S. Tanaka, N. Ikebe, T. Beppu et al., Induction of haem oxygenase-1 nitric oxide and ischaemia in experimental solid tumours and implications for tumour growth. Br. J. Cancer 80, 1945-1954 (1999)
    • (1999) Br. J. Cancer , vol.80 , pp. 1945-1954
    • Doi, K.1    Akaike, T.2    Fujii, S.3    Tanaka, S.4    Ikebe, N.5    Beppu, T.6
  • 44
    • 58849110718 scopus 로고    scopus 로고
    • Haem oxygenase-1 plays a central role in NNK-mediated lung carcinogenesis
    • M.Y. Li, J. Yip, M.K. Hsin, T.S. Mok, Y. Wu, M.J. Underwood et al., Haem oxygenase-1 plays a central role in NNK-mediated lung carcinogenesis. Eur. Respir. J. 32, 911-923 (2008)
    • (2008) Eur. Respir. J. , vol.32 , pp. 911-923
    • Li, M.Y.1    Yip, J.2    Hsin, M.K.3    Mok, T.S.4    Wu, Y.5    Underwood, M.J.6
  • 45
    • 71549142886 scopus 로고    scopus 로고
    • Inhibition of heme oxygenase-1 with an epidermal growth factor receptor inhibitor and cisplatin decreases proliferation of lung cancer A549 cells
    • H. Kuroda, M. Takeno, S. Murakami, N. Miyazawa, T. Kaneko, Y. Ishigatsubo, Inhibition of heme oxygenase-1 with an epidermal growth factor receptor inhibitor and cisplatin decreases proliferation of lung cancer A549 cells. Lung Cancer 67, 31-36 (2010)
    • (2010) Lung Cancer , vol.67 , pp. 31-36
    • Kuroda, H.1    Takeno, M.2    Murakami, S.3    Miyazawa, N.4    Kaneko, T.5    Ishigatsubo, Y.6
  • 46
    • 77957590701 scopus 로고    scopus 로고
    • Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factorkappaB pathway and subsequently downregulating expression of matrix metalloproteinases
    • P.L. Liu, J.R. Tsai, A.L. Charles, J.J. Hwang, S.H. Chou, Y.H. Ping et al., Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factorkappaB pathway and subsequently downregulating expression of matrix metalloproteinases. Mol. Nutr. Food Res. 54(2), S196-S204 (2010)
    • (2010) Mol. Nutr. Food Res. , vol.54 , Issue.2
    • Liu, P.L.1    Tsai, J.R.2    Charles, A.L.3    Hwang, J.J.4    Chou, S.H.5    Ping, Y.H.6
  • 47
    • 0344234407 scopus 로고    scopus 로고
    • Heme oxygenase-1 expression predicts cervical lymph node metastasis of tongue squamous cell carcinomas
    • T. Yanagawa, K. Omura, H. Harada, K. Nakaso, S. Iwasa, Y. Koyama et al., Heme oxygenase-1 expression predicts cervical lymph node metastasis of tongue squamous cell carcinomas. Oral oncology. 40, 21-27 (2004)
    • (2004) Oral oncology. , vol.40 , pp. 21-27
    • Yanagawa, T.1    Omura, K.2    Harada, H.3    Nakaso, K.4    Iwasa, S.5    Koyama, Y.6
  • 48
    • 84861747904 scopus 로고    scopus 로고
    • Expression levels of some antioxidant and epidermal growth factor receptor genes in patients with early-stage non-small cell lung cancer
    • G. De Palma, P. Mozzoni, O. Acampa, E. Internullo, P. Carbognani, M. Rusca et al., Expression levels of some antioxidant and epidermal growth factor receptor genes in patients with early-stage non-small cell lung cancer. Journal of nucleic acids (2010).
    • (2010) Journal of nucleic acids
    • De Palma, G.1    Mozzoni, P.2    Acampa, O.3    Internullo, E.4    Carbognani, P.5    Rusca, M.6
  • 49
    • 33846329139 scopus 로고    scopus 로고
    • Tumour-associated host cells participating at invasion and metastasis: Targets for therapy?
    • M. Mareel, I. Madani, Tumour-associated host cells participating at invasion and metastasis: Targets for therapy? Acta. chirurgica. Belgica. 106, 635-640 (2006)
    • (2006) Acta. Chirurgica. Belgica. , vol.106 , pp. 635-640
    • Mareel, M.1    Madani, I.2
  • 50
    • 28844446987 scopus 로고    scopus 로고
    • Molecular basis of heme oxygenase-1 induction: Implications for chemoprevention and chemoprotection
    • A. Prawan, J.K. Kundu, Y.J. Surh, Molecular basis of heme oxygenase-1 induction: Implications for chemoprevention and chemoprotection. Antioxid. Redox. Signal. 7, 1688-1703 (2005)
    • (2005) Antioxid. Redox. Signal. , vol.7 , pp. 1688-1703
    • Prawan, A.1    Kundu, J.K.2    Surh, Y.J.3
  • 51
    • 0034623211 scopus 로고    scopus 로고
    • Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor
    • J. Alam, C. Wicks, D. Stewart, P. Gong, C. Touchard, S. Otterbein et al., Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor. J. Biol. Chem. 275, 27694-27702 (2000)
    • (2000) J. Biol. Chem. , vol.275 , pp. 27694-27702
    • Alam, J.1    Wicks, C.2    Stewart, D.3    Gong, P.4    Touchard, C.5    Otterbein, S.6
  • 52
    • 15044345354 scopus 로고    scopus 로고
    • Effects of cyclopentenone prostaglandins on the expression of heme oxygenase-1 in MCF-7 cells
    • E.H. Kim, D.H. Kim, H.K. Na, Y.J. Surh, Effects of cyclopentenone prostaglandins on the expression of heme oxygenase-1 in MCF-7 cells. Ann. N. Y. Acad. Sci. 1030, 493-500 (2004)
    • (2004) Ann. N. Y. Acad. Sci. , vol.1030 , pp. 493-500
    • Kim, E.H.1    Kim, D.H.2    Na, H.K.3    Surh, Y.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.