Loss of Gi G-protein-coupled receptor signaling in osteoblasts accelerates bone fracture healing

Journal of Bone and Mineral Research

Volumn 30, Issue 10, 2015, Pages 1896-1904

  Wang, Liping ^a   Hsiao, Edward C ^b   Lieu, Shirley ^b   Scott, Mark ^b   O'Carroll, Dylan ^a   Urrutia, Ashley ^b   Conklin, Bruce R ^b,c   Colnot, Celine ^b,d,e   Nissenson, Robert A ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^d INSERM   (France)

^e IMAGINE INSTITUTE   (France)

Author keywords

fracture repair; G protein coupled receptor signaling; osteoblastic cells

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; DICKKOPF 1 PROTEIN; G PROTEIN COUPLED RECEPTOR; LYMPHOID ENHANCER FACTOR 1; MESSENGER RNA; OSTEOCALCIN; PERTUSSIS TOXIN; RETINOSCHISIN; SOMATOMEDIN C; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9; CYCLIC AMP; DKK1 PROTEIN, MOUSE; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; LEF1 PROTEIN, MOUSE; SIGNAL PEPTIDE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BONE DEVELOPMENT; CALLUS; CONTROLLED STUDY; CORTICAL BONE; ENCHONDRAL OSSIFICATION; FEMALE; FRACTURE HEALING; GENE EXPRESSION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MORPHOMETRICS; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; PROTEIN EXPRESSION; SURFACE PROPERTY; TIBIA FRACTURE; TRABECULAR BONE; WNT SIGNALING PATHWAY; YOUNG ADULT; ANIMAL; FRACTURE; GENETICS; METABOLISM; PATHOLOGY; SECOND MESSENGER; TRANSGENIC MOUSE;

ANIMALS; CYCLIC AMP; FEMALE; FRACTURE HEALING; FRACTURES, BONE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOID ENHANCER-BINDING FACTOR 1; MICE; MICE, TRANSGENIC; OSTEOBLASTS; RECEPTORS, G-PROTEIN-COUPLED; SECOND MESSENGER SYSTEMS;

EID: 84942194888     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.2540     Document Type: Article

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